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  • fatty
  • They also serve as carriers for molecules of low water solubility this way isolating their hydrophobic nature, including lipid-soluble hormones, bile salts, unconjugated bilirubin, free fatty acids (apoprotein), calcium, ions (transferrin), and some drugs like warfarin, phenobutazone, clofibrate & phenytoin. (wikipedia.org)
  • liver disease
  • The results of this study suggested that clofibrate might increase the patient's risk of cancer, liver disease, and pancreatitis (inflammation of the pancreas), although it might also decrease the risk of heart attack. (mayoclinic.org)
  • increase
  • Although mRNA of mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase (mHMGCS) was increased, the β-hydroxybutyrate concentration measured in kidneys did not increase in pigs treated with clofibrate. (mdpi.com)
  • effects
  • Although there is no specific information comparing use of clofibrate in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults. (mayoclinic.org)
  • vehicle
  • Seven days post-MI, animals were further divided to receive vehicle (V) or clofibrate (100 mg/kg, C) for 7 days. (mdpi.com)
  • body
  • In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations. (wikipedia.org)
  • patients
  • Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of clofibrate in children with use in other age groups. (mayoclinic.org)