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Adenocarcinoma, MucinousAdenocarcinomaAppendiceal NeoplasmsCarcinoma, Signet Ring CellProstatePseudomyxoma PeritoneiRectal FistulaCecal NeoplasmsCystadenoma, MucinousUrachal CystCalymmatobacteriumPerineumCystadenocarcinoma, MucinousMucin-2MucinsColorectal NeoplasmsNeoplasm StagingStomach NeoplasmsTumor Markers, BiologicalOvarian NeoplasmsImmunohistochemistryColonic NeoplasmsPrognosisRectal NeoplasmsMicrosatellite InstabilityProstatic NeoplasmsProstate-Specific AntigenKaplan-Meier EstimateLung NeoplasmsPancreatic NeoplasmsEsophageal NeoplasmsCell Line, TumorAdenocarcinoma, PapillaryBarrett EsophagusProstatic HyperplasiaCarcinoma, Pancreatic DuctalAdenocarcinoma, Bronchiolo-AlveolarGene Expression Regulation, NeoplasticAndrogensReceptors, AndrogenProstatectomyOsteitis DeformansPaget's Disease, MammaryPaget Disease, ExtramammaryMyositis, Inclusion BodyCarcinoma, Intraductal, NoninfiltratingMohs SurgeryNipples

PancreaticOvarian mucinousTumorsSerousSituCancerMalignancyDiagnosticRarePatientsPrimaryProstatic adenocarcinomaSerum prostate specifiCarcinomaDuctal adenocarcinomaCancersPrognosisAntigenAcinarColorectal adenocarcinomaNeoplasmsClinicopathologicalGrading of prostate cancerNeoplasiaBRCA1RetrospectivePathologyOvarianInvasiveCytoplasmMorphologicalUrinary bladderLesionsRectumBenignTypicalIncidenceDiagnosisDefinitiveClinicalDataRelevantRare

Pancreatic3

• Rare pancreatic tumors including acinar cell carcinoma, mucinous cystadenocarcinoma or serous cystadenocarcinoma. (sncrf.org)
• Pancreatic adenocarcinoma is not eligible (closed to accrual) 9. (sncrf.org)
• Aruj Chawla, DO discusses a study that brings about a novel method to analyze vascular involvement in pancreatic ductal adenocarcinomas. (arrs.org)

Ovarian mucinous2

• Conclusion: right-sided pelvic lesion consistent with ovarian mucinous cystadenomatous-type lesion. (amsj.org)
• Collins K , Segura S, Hwang M. Endocrine cell micronests in an ovarian mucinous borderline tumor: a potential diagnostic pitfall for microinvasion. (iu.edu)

Tumors2

• Epithelial tumors of nasal cavity, sinuses, nasopharynx: A) Squamous cell carcinoma with variants of nasal cavity, sinuses, and nasopharynx and trachea (excluding laryngeal, nasopharyngeal cancer [NPC], and squamous cell carcinoma of the head and neck [SCCHN]) B) Adenocarcinoma and variants of nasal cavity, sinuses, and nasopharynx (closed to accrual 07/27/2018) 2. (sncrf.org)
• Epithelial tumors of penis - squamous adenocarcinoma cell carcinoma with variants of penis (closed to accrual) 18. (sncrf.org)

Serous1

• Epithelial ovarian cancer is the major ovarian malignancy and comprises five histological subtypes: serous, mucinous, endometrioid, transitional and clear cell [ 3 , 4 ]. (jcancer.org)

Situ4

• This condition is now also referred to as adenocarcinoma in situ, minimally invasive adenocarcinoma, lepidic predominant adenocarcinoma, or invasive mucinous adenocarcinoma 13. (sncrf.org)
• Hello everyone, I am 56-year old former smoker (quit 7 years ago) and was just diagnosed with Adenocarcinoma In Situ based on needle biopsy done on a 1.3cm nodule in my right middle robe. (cancer.org)
• Only adenocarcinoma in situ is identified in the histologic sections examined. (cancer.org)
• Adenocarcinoma in situ was previously known as bronchioloalveolar carcinoma. (cancer.org)

Cancer7

• Her clinical experience is focused on male and female pelvic MRI, including the prostate, uterus, cervix and rectum, liver imaging, functional MRI including dynamic contrast enhanced (DCE) - MRI, DWI and spectroscopy (MRS). She has extensive clinical experience on prostate MRI parallels with building up a highly successful prostate imaging program at MD Anderson Cancer Center. (mdanderson.org)
• Adenocarcinoma with variants of GU system (excluding prostate cancer) (closed to accrual 07/27/2018) 21. (sncrf.org)
• Her family history included bowel, prostate, and breast cancer. (amsj.org)
• Ovarian mesonephric-like adenocarcinoma (MLA) is a rare cancer subtype. (bvsalud.org)
• With not only insidious early symptoms but also limited treatment strategies, approximately 60% of ovarian cancer patients present with distant metastasis upon initial diagnosis, and their overall 5-year relative survival rate is a miserable 46% due to clinically occult dissemination and metastasis [ 5 ]. (jcancer.org)
• Assessing extra-prostatic extension for surgical guidance in prostate cancer: Comparing two PSMA-PET tracers with the standard-of-care. (iu.edu)
• Collins K , Cheng L. Morphologic spectrum of treatment-related changes in prostate tissue and prostate cancer: an updated review. (iu.edu)

Malignancy1

• Toklu A , Mesa H, Collins K . Incidental adrenal hemangioma clinically suspicious for malignancy: diagnostic considerations and review of the literature. (iu.edu)

Diagnostic1

• Dr. Wang's research interests primarily focus on identification of novel imaging techniques and their development into practical and clinically useful diagnostic tools. (ucsf.edu)

Rare1

• Pseudomyxoma peritonei (PMP) is a rare, slow growing mucinous ascites, typically associated with primary appendiceal or ovarian neoplasm [1]. (amsj.org)

Patients2

• Mismatch repair deficiency occurs in 5% to 10% of patients with rectal adenocarcinomas. (cancer.gov)
• 7 , 8 The aim of this review is to explore the molecular pathology research that has been carried out on CRC from Saudi patients, with a view to understanding the prevalence and clinicopathological correlates of clinically and biologically relevant genetic mutations in Saudi CRC patients. (org.sa)

Primary2

• The patient had a past medical history of primary hypothyroidism and depression, both of which were clinically stable. (amsj.org)
• My adenocarcinoma (fast growing, high grade) was diagnosed when my primary was 14cm (almost 6 inches). (cancer.org)

Prostatic adenocarcinoma12

• This case first appeared as Performance Improvement Program in Surgical Pathology (PIP) 2020, Case 29, and is metastatic prostatic adenocarcinoma found in a pre-sacral mass. (cap.org)
• This is most consistent with a diagnosis of metastatic prostatic adenocarcinoma . (cap.org)
• Prostatic adenocarcinoma is the second most common cause of cancer-related death in men. (cap.org)
• The most common histologic type of prostatic adenocarcinoma is acinar adenocarcinoma. (cap.org)
• Acinar prostatic adenocarcinoma cells are cuboidal, with amphophilic to clear cytoplasm and prominent nucleoli. (cap.org)
• These findings are highly suggestive of prostatic adenocarcinoma, but not diagnostic. (cap.org)
• Prostatic adenocarcinoma is graded using the Gleason system, which was developed by Dr. Donald Gleason in 1966. (cap.org)
• The Gleason system uses histoarchitectural patterns to separate prostatic adenocarcinoma into five grades. (cap.org)
• Gleason grades 1 and 2 are no longer used in practice to grade prostatic adenocarcinoma. (cap.org)
• In general, it is not recommended to grade metastatic prostatic adenocarcinoma. (cap.org)
• 13. Mucinous adenocarcinoma of prostate and prostatic adenocarcinoma with mucinous components: a clinicopathological analysis of 143 cases. (nih.gov)
• [ 17 ] Malignant lesions that have to be distinguished from HGPIN include cribriform acinar and cribriform ductal prostatic adenocarcinoma and transitional cell carcinoma that involve prostate ducts and acini. (medscape.com)

Serum prostate specifi3

• The patient's laboratory workup reveals elevated serum prostate specific antigen (PSA) levels. (cap.org)
• Furthermore, the serum prostate-specific antigen (PSA) levels and the ratio of free PSA to unbound PSA can be helpful in avoiding a clinical misdiagnosis [ 15 ]. (biomedcentral.com)
• Annual serum prostate-specific antigen and digital rectal exam screening should begin at age 45. (nih.gov)

Carcinoma4

• Pathognomonic features of carcinoma include circumferential perineural invasion, glomerulations, mucinous fibroplasia, and glands infiltrating adipose tissue. (cap.org)
• 6. Factors affecting recurrence rates after prostatectomy or radiotherapy in localized prostate carcinoma patients with biopsy Gleason score 8 or above. (nih.gov)
• Adenocarcinoma appearing in the rectal wall is not always rectal carcinoma. (biomedcentral.com)
• Pancreatic ductal adenocarcinoma (PDAC) comprises 2% of all cancer diagnoses and is a highly malignant carcinoma, making it the forth leading cause of cancer-related death [ 14 ]. (biomedcentral.com)

Ductal adenocarcinoma2

• Furthermore, it is abundant in almost all examples of conventional ductal adenocarcinoma. (bmj.com)
• The majority of PaCa cases (over 85%) are attributed to pancreatic ductal adenocarcinoma (PDAC) [ 3 ]. (biomedcentral.com)

Cancers5

• This type accounts for greater than 95% of prostate cancers. (cap.org)
• As an alternative to the proteasome itself, recent research has focused on methods to modulate the regulation of deubiquitinating enzymes (DUBs) upstream of the proteasome, identifying DUBs as novel therapeutic targets in breast, endometrial, and prostate cancers, along with multiple myeloma. (oncotarget.com)
• 2 ] Therefore, high-grade serous adenocarcinomas arising from the fallopian tube and elsewhere in the peritoneal cavity, together with most ovarian epithelial cancers, represent extrauterine adenocarcinomas of Müllerian epithelial origin and are staged and treated similarly to ovarian cancer. (gvortho.com)
• Clear cell and endometrioid ovarian cancers that are linked to endometriosis have different gene-expression signatures, as do mucinous subtypes. (gvortho.com)
• BRCA1- and BRCA2- associated hereditary breast and ovarian cancer (HBOC) is characterized by an increased risk for female and male breast cancer, ovarian cancer (including fallopian tube and primary peritoneal cancers), and to a lesser extent other cancers such as prostate cancer, pancreatic cancer, and melanoma primarily in individuals with a BRCA2 pathogenic variant . (nih.gov)

Prognosis2

• 3. Prognosis of mucinous adenocarcinoma of the prostate treated by radical prostatectomy: a study of 47 cases. (nih.gov)
• Villoglandular Pattern in HPV-associated Endocervical Adenocarcinoma is Associated With Excellent Prognosis: A Reappraisal of 31 Cases Using IECC and Silva Pattern Classification. (patologia.ro)

Antigen1

• 15. The results of radical prostatectomy at a community hospital during the prostate specific antigen era. (nih.gov)

Acinar2

• Acinar adenocarcinoma occurs predominantly in the posterolateral aspects (peripheral zone) of the prostate. (cap.org)
• 4. Acinar with ductal and mucinous adenocarcinoma of prostate cancer complicated with lung metastasis: a case report and literature review. (nih.gov)

Colorectal adenocarcinoma2

• Association of HPV with genetic and epigenetic alterations in colorectal adenocarcinoma from Indian population. (cdc.gov)
• The purpose of this study was to count the number of lymphatic channels present in colorectal adenocarcinoma and correlate it with site, size, and stage of tumor, lymph node metastasis. (ijpmonline.org)

Neoplasms2

• In contrast, MUC2 is rarely detectable in aggressive pancreatic tumours, but is commonly expressed in intraductal papillary mucinous neoplasms (IPMNs), which are rare, indolent tumours, in intestinal IPMNs, and in indolent colloid carcinomas. (bmj.com)
• These are intraductal papillary mucinous neoplasms (IPMNs), characterised by clinically detectable papillary tumours that grow within and lead to pronounced cystic dilatation of the ducts (mass forming preinvasive neoplasia). (bmj.com)

Clinicopathological1

• In the present study, we retrospectively analyzed 9504 cases diagnosed as rectal cancer in our hospital from 2003 to 2015, and report the clinicopathological characteristics of 9 cases of prostate cancer with rectal wall invasion misdiagnosed as rectal cancer. (biomedcentral.com)

Grading of prostate cancer1

• In November, 2014, 65 prostate cancer pathology experts, along with 17 clinicians including urologists, radiation oncologists, and medical oncologists from 19 different countries gathered in a consensus conference to update the grading of prostate cancer, last revised in 2005. (nih.gov)

Neoplasia2

• Morphological spectrum for normal prostate to high-grade prostatic intraepithelial neoplasia. (medscape.com)
• Cite this: High-Grade Prostatic Intraepithelial Neoplasia and Other Proposed Preneoplastic Lesions in the Prostate - Medscape - Mar 22, 2007. (medscape.com)

BRCA11

• Mucinous Histology, BRCA1/2 Mutations, and Elevated Tumor Mutational Burden in Colorectal Cancer. (cdc.gov)

Retrospective2

• The first two reference sets (A and B) are retrospective where select clinically annotated samples currently stored in freezers are provided by six institutions around the country. (nih.gov)
• Horizontal tumor extent (HZTE) has limited prognostic significance in 2018 FIGO stage I endocervical adenocarcinoma (ECA): a retrospective study of 416 cases. (patologia.ro)

Pathology1

• The surgical pathology database at the Department of Pathology (2003-2015) was searched for cases of prostate cancer with rectal wall involvement. (biomedcentral.com)

Ovarian1

• Ovarian mesonephric-like adenocarcinoma (MLA) is a rare cancer subtype. (bvsalud.org)

Invasive1

• Clear Cell Adenocarcinoma In Situ as a Potential Precursor Lesion for Sporadic Invasive Endocervical Clear Cell Adenocarcinoma. (patologia.ro)

Cytoplasm1

• Similarly to adenocarcinoma, the cytoplasm of cells in most HGPIN cases stains positively for an antibody to α-methylacyl-CoA racemase (AMACR). (medscape.com)

Morphological1

• A definitive diagnosis of prostate cancer invading the rectum can be made based on the patients' history, the morphological features of the cancer, and immunohistochemical (IHC) analyses. (biomedcentral.com)

Urinary bladder1

• The prostate is located in the pelvis, under the urinary bladder and in front of the rectum. (biomedcentral.com)

Lesions1

• Aim 1: Collect premalignant lesions (PML) and their associated microenvironment via LCM from FFPE tissue across four organ sites (breast, lung, pancreas & prostate). (nih.gov)

Rectum1

• Because of its proximity to the rectum, prostate cancer can be misdiagnosed as rectal cancer. (biomedcentral.com)

Benign1

• [13] first described bone formation within a benign tubulovillous adenoma without signs of necrosis or mucinous accumulation. (advbiores.net)

Typical2

• Appendiceal adenocarcinomas and appendiceal typical carcinoid tumors are similar to those derived in the colon. (gobletcellcarcinoid.org.uk)
• Typical features of adenocarcinomas on cytology (Pap stain). (patholines.org)

Incidence2

• In China, the incidence rate of prostate cancer was 1.6/100 000 individuals. (biomedcentral.com)
• With more comprehensive screening techniques being increasingly used in China, the incidence of prostate cancer may rapidly increase in the future [ 2 ]. (biomedcentral.com)

Diagnosis2

• All patients underwent standard therapy for prostate cancer after the definitive pathological diagnosis. (biomedcentral.com)
• It is necessary to perform a differential diagnosis for prostate cancer in cases of rectal malignant tumors in elderly male patients. (biomedcentral.com)

Definitive1

• 8. Improvement in relapse-free survival throughout the PSA era in patients with localized prostate cancer treated with definitive radiotherapy: year of treatment an independent predictor of outcome. (nih.gov)

Clinical1

• Clinical outcomes would support a resection as a recommended clinically valid option. (biomedcentral.com)

Data1

• 4 It has also hindered the sharing of clinically meaningful data among multiple institutions. (bapath.org)

Relevant1

• Using an in vitro model consisting of dissociated primary cultured mouse neurons we demonstrate abnormal pre- and post-synaptic marker expression after a clinically relevant isoflurane anesthesia exposure conducted during neuron development. (preprints.org)

Rare1

• In sharp contrast to MUC1, MUC2 is almost never detectable in PanINs or conventional adenocarcinomas, but instead, it is commonly expressed in a rare but distinctive set of tumours that appear to form a distinct and indolent pathway of carcinogenesis. (bmj.com)