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  • Murmurs
  • Babies with murmurs at neonatal or 6 week examinations should be referred for early paediatric cardiological evaluation which will result either in a definitive diagnosis of congenital heart disease or in authoritative reassurance of normal cardiac anatomy and function. (bmj.com)
  • lesions
  • In the present study, data recorded in the National Register for Congenital Heart Defects with respect to the prevalence of specific lesions and sex distribution are compared with that recorded in a published German prevalence study (Prevalence Study) and with the meta-analysis by van der Linde et al. (cambridge.org)
  • interventional cardiac
  • The primary implanting physician has performed ≥ 25 interventional cardiac procedures involving a trans-septal puncture (TSP) in their total experience, with at least 10 TSP procedures performed over the past 12 month period. (cms.gov)
  • precordial
  • Multiple precordial and subcostal echocardiographic planes were scanned in each patient in an attempt to identify the defects. (bmj.com)
  • Cardiac exam reveals mildly increased right precordial activity, regular rhythm, and normal first and second heart sounds. (ipmsstockholm.org)
  • valvular
  • Valvular defects - Normal blood flow depends upon fully functioning heart valves. (medstargeorgetown.org)
  • Guidelines for the use of surgery in patients with valvular disease have been developed by a joint task force of the American College of Cardiology and the American Heart Association. (aafp.org)
  • infants
  • 1 Examination before first discharge from hospital and of infants at 6 weeks of age for signs of congenital heart disease is recommended in Health for All Children . (bmj.com)
  • shunt
  • Lung perfusion scintillation on the eighth postoperative day showed partial defects in the bilateral lower-lung regions, and no intrapulmonary shunt. (asahq.org)
  • venous
  • During Inspiration the Pressure in the Thorax (Intra-thoracic Pressure) reduces in order to facilitate the entry of air into the lungs, as the pressure decreases, the venous return to the Right side of the Heart Increases. (epomedicine.com)
  • The venous return to the right ventricle (RV) increases during inspiration due to negative intrathoracic pressure and P2 is even more delayed, so it is normal for the split of the second heart sound to widen during inspiration and to narrow during expiration. (50r.in)
  • a) RV volume overload, such as atrial septal defect (ASD) and anomalous pulmonary venous connection. (50r.in)
  • children
  • It was shown that the mean body surface area-standardized AV septal length (AVSL) was significantly shorter in the NSAVSD parents and siblings than in parents and siblings of syndromic AVSD case and control children. (uiowa.edu)
  • Sinus arrhythmia in children with atrial septal defect: an analysis of heart rate variability before and after surgical repair. (explainmedicine.com)
  • abnormal
  • At a cellular level, ion-channel defects, such as LQTS, allow abnormal cellular automaticity to trigger potentially fatal polymorphic VT, also known as torsade de pointes. (medscape.com)
  • blood
  • A murmur is a sound generated by abnormally turbulent flow of blood through the heart. (medicinenet.com)
  • These defects can affect heart function and blood flow. (medstargeorgetown.org)
  • It functions as a barrier that prevents blood from passing from one side of your heart to the other. (medstargeorgetown.org)
  • Defects in these critical arteries and veins can prevent oxygen-rich blood from reaching the rest of the body. (medstargeorgetown.org)
  • Major blood vessel defects can seriously affect heart function and overall health. (medstargeorgetown.org)
  • Also during Inspiration the lung increase in volume and there occurs pooling of blood in the Pulmonary Vasculature leading to reduced filling of the Left Side of the Heart compared to the Right Side. (epomedicine.com)
  • Because rVSD is often considered to be hemodynamically benign, meaning that blood flow appears normal, it is assumed that whole heart function is a reflection of conditions at the cellular and molecular levels. (scienceblog.com)
  • Disease
  • A VSD, therefore, is a type of congenital heart disease (CHD). (medicinenet.com)
  • Congenital heart disease (CHD) has a complex genetic etiology, and recent studies suggest that high penetrance de novo mutations may account for only a small fraction of disease. (plos.org)
  • Congenital heart disease (CHD) is a leading cause of childhood morbidity in the developed world. (plos.org)
  • There are few prevalent clinical risk factors and though it is possible that up to 90% of risk for CHD may be genetic, the number of genes clinically associated with disease is small. (plos.org)
  • Some structural heart disease is congenital (present at birth), while other cases develop later in life, due to injury, infection, or aging. (medstargeorgetown.org)
  • AIM To investigate the performance of routine neonatal and 6 week examinations for detecting congenital heart disease. (bmj.com)
  • A normal examination does not exclude heart disease. (bmj.com)
  • Unrecognised neonatal heart disease carries a serious risk of avoidable mortality, morbidity, and handicap. (bmj.com)
  • We have now examined the performance of these two routine examinations in detecting all congenital heart disease within a large, geographically defined, population over a period of eight years. (bmj.com)
  • We undertook a retrospective study of all cases of structural congenital heart disease diagnosed by the age of 12 months in babies live born in the northern health region of the UK between 1987 and 1994. (bmj.com)
  • Methods and Results Clinical evaluations and genetic linkage analyses were performed in five additional kindreds with Holt-Oram syndrome and also in one kindred with heart-hand syndrome type III and one kindred with familial atrial septal defect and conduction disease. (ahajournals.org)
  • Conditions that clinically appear to be partial phenocopies of Holt-Oram syndrome arise from distinct disease genes. (ahajournals.org)
  • What are the two main causes of acyanotic congenital heart disease? (brainscape.com)
  • Angled views in cineangiocardiography of congenital heart disease. (ahajournals.org)
  • birth
  • Risk factors associated with NSAVSD were examined using the 1997-2005 National Birth Defects Prevention Study database. (uiowa.edu)
  • Vitamin k independent warfarin resistance after birth in women with previous heart transplant recipients. (roanokechowan.edu)
  • Cardiology
  • The recently published study appears in the Journal of Molecular and Cellular Cardiology , the official journal of the International Society for Heart Research. (scienceblog.com)