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  • treatments
  • Fetal tissue is also being used to understand and to develop potential treatments for global public health problems such as Zika virus and HIV/AIDS. (scienceinpublic.com.au)
  • The results of the study were mixed some patients showed vast improvement while others showed little and Freed speculates about why this was and what it means for future treatments and research. (sirsi.net)
  • Researchers from The University of Texas Medical Branch at Galveston, led by prostate cancer treatment pioneer Dr. Eric Walser, have shown that selectively destroying cancerous prostate tissue is as effective as complete prostate removal or radiation therapy while preserving more sexual and urinary function than the other treatments. (news-medical.net)
  • Along with more than 100 patient and research groups opposing the bill, we believe it will put patients at risk and undermine the effective FDA Expanded Access Program already in place to give seriously ill patients access to experimental treatments. (isscr.org)
  • donor
  • The NIH Revitalization Act of 1993 imposed additional restrictions on fetal tissue research, including mandated written informed consent from the donor as well as a signed statement from the attending physician affirming that the decision to abort and the decision to donate tissue for research are not related. (statnews.com)
  • Nevertheless, there is still no consensus on some fundamental questions regarding optimal donor age, amount of tissue required, optimal site of implantation, patient selection, and the use of immunosuppression. (ucdavis.edu)
  • scientists
  • Scientists can also reprogram adult cells to act like embryonic stem cells, but these reprogrammed cells, while useful for research, have not been shown to be therapeutically safe . (slate.com)
  • researchers
  • Fact #3: Non-fetal tissue sources are available to researchers and saving lives today . (lozierinstitute.org)
  • One of the many discoveries researchers made in preparing for the first trial was that fetal stem cells seemed to be the best stem cells for ALS treatment. (slate.com)
  • For their trial, researchers used stem cells that were beginning to develop into nerve cells. (slate.com)
  • Using fetal brain tissue, researchers have discovered that the production of new brain cells, which normally continues throughout fetal development, is impaired by premature birth. (isscr.org)
  • If passed, the bill would effectively halt valuable work in scores of laboratories at the UW-Madison, the Medical College of Wisconsin and beyond, shut down long-standing research projects and essentially chase many researchers and emerging companies out of the state. (wisconsintechnologycouncil.com)
  • Early results from an innovative new clinical trial led by researchers from Queen's University Belfast have shown that men with prostate cancer could benefit from radical radiotherapy that delivers treatment in just five visits instead of the usual 37. (news-medical.net)
  • New research from a Swedish and Danish team of researchers led from Karolinska Institutet lend additional support to a link between treatment with fluoroquinolone antibiotics and an increased risk of acute aortic disease. (news-medical.net)
  • Several researchers have proposed ways to enhance graft survival (5) and increase the availability of the procedure by replacing fetal tissue with alternative tissue sources such as xenograft (6). (ucdavis.edu)
  • important gene associated
  • An important gene associated with Fetal Akinesia Deformation Sequence is RAPSN (Receptor Associated Protein Of The Synapse), and among its related pathways/superpathways are Agrin Interactions at Neuromuscular Junction and Succinylcholine Pathway, Pharmacokinetics/Pharmacodynamics . (malacards.org)
  • An important gene associated with Fetal Hemoglobin Quantitative Trait Locus 1 is HBG1 (Hemoglobin Subunit Gamma 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Glucose / Energy Metabolism . (malacards.org)
  • CIRM
  • CIRM has funded early-stage awards whose research has progressed into clinical trials. (ca.gov)
  • Below is a list of clinical trials that are a result of these early-stage CIRM-funded awards. (ca.gov)
  • For a list of CIRM-funded trials, visit our Funding Clinical Trials page. (ca.gov)
  • The professor of ophthalmology, biomedical engineering, and cell and neurobiology at USC is being funded by CIRM to carry out an FDA-approved clinical trial . (ca.gov)
  • This gene correction approach for severe combined immunodeficiency (SCID) has already transformed the lives of dozens of children treated in early trials and CIRM is pleased to be a partner on the confirmatory trial for this transformative treatment for patients born with this fatal immune disorder," says Sohel Talib, CIRM's Associate Director Therapeutics and Industry Alliance. (ca.gov)
  • Dr. Kohn, now a member of Orchard's scientific advisory board, said: "CIRM funding has been essential to the overall success of my work, supporting me in navigating the complex regulatory steps of drug development, including interactions with FDA and toxicology studies that enhanced and helped drive the ADA-SCID clinical trial. (ca.gov)
  • Since CIRM was created by the voters of California the Agency has been able to use its support for research to leverage an additional $1.9 billion in funds for California. (ca.gov)
  • That money comes in the form of co-funding from companies to support their own projects, partnerships between outside investors or industry groups with CIRM-funded companies to help advance research, and additional funding that companies are able to attract to a project because of CIRM funding. (ca.gov)
  • hemoglobin
  • Delta-beta thalassemia is a hemoglobin disorder characterized by decreased or absent synthesis of the delta- and beta-globin chains with a compensatory increase in expression of fetal gamma-chain synthesis from the affected chromosome. (malacards.org)
  • Fetal Hemoglobin Quantitative Trait Locus 1, also known as delta-beta thalassemia , is related to hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome and hereditary persistence of fetal hemoglobin-sickle cell disease syndrome . (malacards.org)
  • Malik's innovation flows from the observation that some adults never stop producing fetal hemoglobin (HbF), which prevents red blood cell sickling when present in the body in sufficient quantity. (cincinnatichildrens.org)
  • Normally, the fetal hemoglobin gene switches off shortly after birth. (cincinnatichildrens.org)
  • Secondly
  • Secondly, I will utilise an in vitro culture system to identify the transcriptional networks responsible for the maturation of the foetal intestinal epithelium. (europa.eu)
  • implantation
  • We report the case of a 52-year-old man, who, 23 months earlier, received both intrastriatal implantation and intraventricular infusion of tissues derived from fetuses of 15 to 16 weeks and 5 to 6 weeks gestational age. (hematopoiesis.info)
  • Phase
  • The experimental treatment slowed or reversed the progression of the disease in several patients in a small Phase I clinical trial. (slate.com)
  • congenital
  • 76 Fetal akinesia deformation sequence: A clinically and genetically heterogeneous group of disorders with congenital malformations related to impaired fetal movement. (malacards.org)
  • Ongoing
  • A joint Veterans Administration -NIH clinical trial confirmed the benefits of DBS for advanced PD, and efforts to improve DBS are ongoing. (nih.gov)
  • Findings
  • I'll try to summarize only some histological findings of individuals who underwent clinical neurotransplantation and eventually died from different reasons. (hematopoiesis.info)
  • ethical
  • Focuses on ethical and public policy issues in health care and biomedical research. (georgetown.edu)
  • Provides references to resources on ethical and public policy issues in medicine and biomedical research. (georgetown.edu)
  • A proportionate approach to assessing the ethical acceptability of the research, at either level of review, involves consideration of the foreseeable risks, the potential benefits, and the ethical implications of the research. (sfu.ca)
  • including lung
  • 58 The fetal akinesia deformation sequence (FADS) refers to a clinically and genetically heterogeneous constellation of features including fetal akinesia, intrauterine growth retardation, arthrogryposis, and developmental anomalies, including lung hypoplasia, cleft palate, and cryptorchidism (Vogt et al. (malacards.org)
  • vaccines
  • It is currently being used to develop and test vaccines for potential treatment of influenza, dengue fever, HIV/AIDS, and hepatitis B and C. It is vital for research in other areas as well. (statnews.com)
  • biomedical
  • Federal law was adjusted in 1975 to add language clarifying that this research be "conducted only in accordance with any applicable State or local laws regarding such activities," and only for "the development of important biomedical knowledge which cannot be obtained by other means. (statnews.com)
  • The ISSCR is opposed to recent efforts to inappropriately limit or prohibit biomedical research using fetal tissue. (isscr.org)
  • Finally, we made an overview about current biomedical research using differentiated hPSCs. (frontiersin.org)
  • One major challenge in biomedical research is to recapitulate in vitro the biological events occurring in vivo in normal or diseased organs. (frontiersin.org)
  • Many persons who are interested in medical ethics and biomedical research have asked for a guide to the literature. (georgetown.edu)
  • The ISSCR writes in support of the National Association for Biomedical Research (NABR) complaint requesting relief from discriminatory airline carriage policies that impede the transportation of animals for biomedical research. (isscr.org)
  • 2018
  • Men who have been newly diagnosed with prostate cancer say they would trade some improvement in their odds of survival for improvements in side effects and quality of life, according to research presented at the 2018 NCRI Cancer Conference. (news-medical.net)
  • decades
  • The tissue used in this research would otherwise be discarded, and safeguards have been in place for decades to ensure that the tissue is obtained and used ethically. (statnews.com)
  • Though it may take years or decades before this procedure becomes common clinical practice, it gives millions of Americans with PD (and their families) a good reason to hope. (ucdavis.edu)
  • valuable consideration
  • This effort, to separate tissue donation from any incentive, is accompanied by laws that apply significant criminal and civil penalties for the purchase or sale of fetal tissue, or for soliciting or acquiring fetal tissue after providing "valuable consideration" for the costs associated with the abortion itself. (statnews.com)
  • involves
  • it involves supporting the research at every stage and creating partnerships to help it fulfill its potential," says Dr. Millan. (ca.gov)