Clinical tetracycline resistance. Medical search. Frequent questions

All human isolates were sensitive to several common antibiotics used in clinical practice, such as ciprofloxacin, gentamicin, and trimethoprim-sulfamethoxazole. (cdc.gov)
This phenotype of bacteria are resistant to the macrolide-lincosamide-streptogramin B group of antibiotics, however, the resistance mechanism is only induced by the presence of 14-membered ring macrolides, such as erythromycin. (wikipedia.org)
Tetracycline antibiotics should not be used for streptococcal diseases unless the organism has been demonstrated to be susceptible. (nih.gov)
The data suggest that the mucoid phenotype could be associated with extrachromsomal element(s) carrying resistance genes to antibiotics and that these extrachromosomal elements may not harbour resistance determinants to chloramphenicol. (scirp.org)
Oxytetracycline is a product of the metabolism of Streptomyces rimosus and is one of the family of tetracycline antibiotics. (globalrph.com)
Many commensals and pathogenic organisms have developed resistance to well established and newer antibiotics. (jidc.org)
8- Neisseria Gonorrhea has developed a resistance to all but one class of antibiotics used to treat Syphilis in the USA. (amhe.org)
Tetracyclines are antimicrobial antibiotics that inhibit bacterial ribosomes which are the organelles that make proteins. (osmosis.org)
Tetracyclines are a class of antibiotics that inhibit bacterial protein synthesis by binding to the 30s subunit of their ribosomes and preventing tRNA from binding. (osmosis.org)
Tetracyclines are broad-spectrum antibiotics, effective against many common gram-positive and gram-negative bacteria, as well as certain types of anaerobic and atypical bacteria. (osmosis.org)
Tetracyclines are antibiotics made up of a four-ring system. (goldbio.com)
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. (goldbio.com)
Susceptibility of N. gonorrhoeae to five antibiotics (ciprofloxacin, ceftriaxone, spectinomycin, penicillin G and tetracycline) was tested systematically. (medicaljournals.se)
Sequencing of DNA from the pipe samples revealed a diverse reservoir of antibiotic-resistance genes (ARGs), and the most ARGs observed were those encoding resistant to commonly used antibiotics, including tetracyclines, fluoroquinolones, beta-lactams, and macrolides. (umn.edu)
3 All of these general precautions, as well as discontinuing of antibiotics when deemed unnecessary, will aid to reduce the rate of antibiotic resistance. (skintherapyletter.com)
5 The American Academy of Dermatology (AAD) guidelines recommend coadministration of benzoyl peroxide, a topical bactericidal agent not reported to cause resistance, together with both topical and oral antibiotics. (skintherapyletter.com)
6,7 Added to topical antibiotics, benzoyl peroxide may prevent the formation of resistance and increase treatment efficacy. (skintherapyletter.com)
Monitoring resistance to antibiotics in wild animals may assist in evaluating tendencies in the evolution of this major public health problem. (mdpi.com)
Regulatory controls and prudent‐use practices are the primary strategies used to control resistance, and these are probably very important to limit the emergence of resistance to new antibiotics. (beefresearch.org)
While methicillin is no longer used in clinical practice, the term MRSA is used to encompass resistance to commercially available antibiotics such as β-lactams 3 . (randox.com)
While methicillin has lost its clinical utility due to the emergent resistance, MRSA is used to describe S. aureus which displays resistance to penicillin-like antibiotics such as amoxicillin and oxacillin, as well as other forms of commercially available antibiotics like macrolides, tetracyclines, and fluroquinolones 4 . (randox.com)
Since current antibiotics are rapidly becoming ineffective, novel strategies to combat resistance are needed. (hal.science)
In recent years, because of overuse of antibiotics and transition of resistance genes, frequency of resistant staphylococcal infections, are increasing. (alliedacademies.org)
In Staphylococcus resistance to these antibiotics is create by methylation of target site on ribosome that mostly related to methylase gene erm (rRNA) [ 12 ]. (alliedacademies.org)
The 16.9% the strains presented multiple resistance (3 or more antibiotics) with 37 different phenotypes. (bvsalud.org)
The emergence of antimicrobial drug resistance following the introduction of antibiotics is a commonly reported global phenomenon. (who.int)
Vibrio cholerae remained susceptible to many antibiotics for a sustained period, with only 3% of the isolates demonstrating resistance in the worldwide survey conducted in 1976. (who.int)
7 However, during the past two decades, reports from several cholera-endemic countries of strains resistant to antibiotics including tetracycline, ampicillin, kanamycin, streptomycin, sulphonamides, trimethoprim and gentamicin have appeared. (who.int)
Susceptibility to different antibiotics was tested by disk diffusion technique 11 following the Clinical and Laboratory Standards Institute (CLSI) guidelines 12 using a commercially available disk (Oxoid Ltd, England) of eight antimicrobial agents: amoxycillin (10 μg/disc), chloramphenicol (30 μg/disc), ciprofloxacin (5 μg/disc), erythromycin (15 μg/disc), nalidixic acid (30 μg/disc), norfloxacin (10 μg/disc), co-trimoxazole (25 μg/disc) and tetracycline (30 μg/disc). (who.int)

All four (100%) isolates tested were resistant to ampicillin and tetracycline. (cdc.gov)
Agreement between ceftiofur resistance and coresistance to ampicillin, chloramphenicol, streptomycin, sulfisoxazole, and tetracycline was almost perfect (κ 0.97). (avma.org)
Five P. multocida isolates (3.6%), all obtained from NSW in 2019, exhibited dual resistance to macrolides and tetracycline, and a further two Queensland isolates from 2019 (1.4%) exhibited a multidrug-resistant phenotype to ampicillin/penicillin, tetracycline, and tilmicosin. (edu.au)
Illumina whole genome sequencing identified the genes msr(E) and mph(E)encoding macrolide resistance, tet(R)-tet(H) or tet(Y) encoding tetracycline resistance, and blaROB-1 encoding ampicillin/penicillin resistance in all isolates exhibiting a corresponding resistant phenotype. (edu.au)
Nalidixic, Ampicillin and Nitrofurantoin, to a lesser degree resistance to cephalosporins (C3ªG) and ciprofloxacin was evidenced. (bvsalud.org)

Whilst these data do not enable us to determine if resistance genes were transferred from patient to the wastewater system or indeed vice versa, they do allow us to confirm crossover in the resistome of clinically-relevant pathogens and the microbiome of the wastewater environment," the study authors wrote. (umn.edu)
The aims of this research work were to determine the patterns of antibiotic resistance in Escherichia coli isolates from the meat of wild or domestically reared pigeons from Spain, to detect the presence of virulence and antibiotic resistance genes, and to carry out a phylogenetic classification of the isolates. (mdpi.com)
The aim of this study was to characterize the erythromycin and tetracycline resistance genes of S. gallolyticus subsp. (clin-lab-publications.com)
The erythromycin and tetracycline susceptibilities were determined by disk diffusion and agar dilution methods, while the resistance genes were identified by nucleotide sequence analysis. (clin-lab-publications.com)
For tetracycline resistance genes, tet(L) and tet(M) were detected at 13.9% and 11.1%, respectively. (clin-lab-publications.com)
Conclusions: A number of erythromycin and tetracycline resistance genes were detected in S. gallolyticus subsp. (clin-lab-publications.com)
Tigecycline is a new-generation of tetracycline (glycylcyclines) and is active in vitro against bacteria that possess any of the classical genes that confer tetracycline resistance through ribosomal protection or efflux pumps. (druglib.com)
We show that this method activates the resistance genes while not having any antibacterial activity against susceptible bacteria. (beefresearch.org)
Subsequently, we harvested RNA from the bacteria and used a molecular assay (real‐time PCR) to quantify changes in expression of two tetracycline efflux pump genes. (beefresearch.org)
We also found β-lactamase, tetracycline and multiple antibiotic resistance genes, as well as adherence, iron acquisition, toxins (aerolysin family, haemolysins) and diverse protease genes. (int-res.com)
Resistance to nafcillin by mecA gene which is located on chromosome, resistance to vancomycin (vancomycin and nafcillin resistance genes exist in these strains) and plasmid resistance to tetracycline, erythromycin and aminoglycosides are the types of resistance mechanisms [ 5 , 6 ]. (alliedacademies.org)
Antimicrobial susceptibility testing was done using the Clinical and Laboratory Standards Institute guidelines (2017) and genes encoding resistance to beta-lactams, fluoroquinolones and aminoglycosides were identified by polymerase chain reaction and sequencing. (bvsalud.org)

When penicillin is contraindicated, tetracyclines are alternative drugs in the treatment of infections caused by the cited microorganisms. (nih.gov)
10- In Massachusetts, the Department of health issued in January 2023 a clinical advisory announcing a novel strain of multidrug-non-susceptible Neisseria Gonorrhea decrease sensibility to a resistance to drugs like ciprofloxacin, penicillin, cefixime, azithromycin. (amhe.org)
The MICs of all cephalosporins, tetracycline, trimethoprim-sulfamethoxazole, and chloramphenicol increased along with the MICs of penicillin G. However, erythromycin resistance and clindamycin resistance were observed more frequently among the intermediately penicillin-resistant strains. (inspq.qc.ca)
Multiple resistance was observed for 32 strains, of which 25 were highly resistant to penicillin G and belong to SGT 23F. (inspq.qc.ca)
Overall, the resistance levels to tetracycline, ciprofloxacin and penicillin G were relatively stable. (biomedcentral.com)
During 2010-2013, the N. gonorrhoeae population in Belarus displayed high and relatively stable resistance levels to tetracycline, ciprofloxacin, and penicillin G, while the resistance to azithromycin declined. (biomedcentral.com)
A global phylogeny of CC230 (n=389) revealed that tet(S/M)-positive isolates formed a sublineage predicted to exhibit resistance to penicillin, co-trimoxazole, erythromycin and tetracycline. (ox.ac.uk)

CDC's National Antimicrobial Resistance Monitoring System (NARMS) laboratory conducted antibiotic resistance testing on clinical isolates collected from four ill people infected with the outbreak strains. (cdc.gov)
Because many strains of the following gram-positive microorganisms have been shown to be resistant to tetracyclines, culture and susceptibility testing are especially recommended. (nih.gov)
The Multiple Antibiotic Resistance (MAR) index shows the themucoid strains with a high MAR index range of 0.7 - 1.0 with a median MAR index of 0.8, while the non-mucoid strains had a MAR index of 0.2 - 0.8 with a median MAR index of 0.35. (scirp.org)
Furthermore, the extrachromosomal elements bearing the mucoid phenotype and the resistance elements in the mucoid strains do not significantly impact on the fitness of the cognate strain. (scirp.org)
Up to 44 percent of strains of Streptococcus pyogenes and 74 percent of Streptococcus faecalis have been found to be resistant to tetracycline drugs. (globalrph.com)
The MIC values for enrofloxacin against these isolates are presented in Table I. Most strains of these organisms were found to be susceptible to enrofloxacin in vitro but the clinical significance has not been determined for some of the isolates. (drugs.com)
The serogroup/serotypes (SGTs) and antimicrobial susceptibilities to 10 antimicrobial agents of 110 clinical strains of Streptococcus pneumoniae were determined. (inspq.qc.ca)
This report describes the first isolation of VISA from a patient in the United States, which may be an early warning that S. aureus strains with full resistance to vancomycin will emerge. (cdc.gov)
Epidemiologic and laboratory investigations are under way to assess the risk for person-to-person transmission of VISA and to determine the mechanism(s) by which these strains develop resistance. (cdc.gov)
This report documents the emergence of VISA in the United States and may signal the eventual emergence of S. aureus strains with full resistance to vancomycin. (cdc.gov)
We present our study on the efficacy and phenotypic impact of compensatory evolution in Escherichia coli strains carrying multiple resistance mutations. (elifesciences.org)
In the context of our continuing studies, the effective approach of antibiotic-adjuvant was investigated against a large panel of P. aeruginosa Tunisian clinical strains collected from the Military Hospital of Tunis. (hal.science)
Increasing of MLS (Macrolide-Lincosamide-Streptogramin) resistant strains in clinical specimens, indicates increasing of clindamycin utilization [ 11 ]. (alliedacademies.org)
In total, 114 217 test results were included for the clinical isolates, and 3582 test results for control strains. (lu.se)
However, resistance zole-resistant strains of H. pylori . (who.int)
A total of 668 Salmonella strains isolated in the years 2017, 2018 and 2019 were analyzed from human and food clinical samples, at the Central Public Health Laboratory and / or sent by Laboratories of the Enteropathogens Network. (bvsalud.org)

While tetracyclines, macrolides, lincosamides, and quinolones have historically been used for treatment of infections due to these organisms, acquired resistance is now well documented and varies according to drug, organism, and patient population. (medscape.com)
The Staphylococcus which are resistant to erythromycin show cross-resistance with macrolides (spiramycin, azithromycin and clarithromycin), lincosamides (clindamycin and lincomycin) and type B streptogramin. (alliedacademies.org)

Commonly used antimicrobial regimens consisted of streptomycin plus tetracycline or rifampicin plus doxycycline given for 6 weeks. (qxmd.com)
Philip K. Russell, MD ment and prophylaxis with streptomycin or gentamicin or the tetracycline or fluoro- quinolone classes of antimicrobials would be advised. (cdc.gov)

Susceptibility testing should be performed with tetracycline since it predicts susceptibility to minocycline. (nih.gov)
In vitro susceptibility testing and molecular resistance testing may be useful to guide therapy, especially for disseminated infections if available. (medscape.com)
Here, the susceptibility of Mannheimia haemolytica and Pasteurella multicoda isolates obtained from BRD clinical cases (deep lung swabs at post-mortem) among feedlots in four Australian states (2014-2019) was determined for 19 antimicrobial agents. (edu.au)
Results The method, called normalized interpretation of antimicrobial resistance, was tested on results from the KS and VX clinical microbiology laboratories, using the disk diffusion method for antimicrobial susceptibility tests, and for two bacterial species, Staphylococcus aureus and Escherichia coli. (lu.se)
Tetracycline susceptibility testing results were available for 121 tet(S/M)-positive isolates and all were resistant. (ox.ac.uk)
12,13 Since there is no Vibrio cholerae -specific CLSI interpretive criteria for several of the drugs for which resistance is described, we considered a zone of inhibition of 21mm for ciprofloxacin, 23mm for erythromycin, 19mm for nalidixic acid and 17mm for norfloxacin as the cut-off values to determine susceptibility ( Table 1 ). (who.int)

Comparison with the results of the 1998 epidemic suggests a worrying increase in the resistance of V. cholerae to erythromycin, doxycycline and ciprofloxacin. (who.int)

Results -Resistance to 1 or more antimicrobials was detected in 986 of 1,441 (68.4%) isolates recovered. (avma.org)
The containment of the phenomenon of resistance towards antimicrobials is a priority, especially in preserving molecules acting against Gram-negative pathogens, which represent the isolates more frequently found in the fragile population of patients admitted to Intensive Care Units. (mdpi.com)
CONCLUSIONS: Raw sewage has been considered a valuable tool to evaluate epidemiological population patterns and this study supports the view that NTS with pathogenic potential and resistance to antimicrobials are circulating in the studied region. (bvsalud.org)
4 Indiscriminate use of antimicrobials is one of the commonest reasons for emergence of resistance. (who.int)

2 Department of Clinical Microbiology, Abubakar Tafawa Balewa University Teaching Hospital, Bauchi, Nigeria . (scirp.org)

According to Shomron 7 (2010), this field of the clinical pharmacology studies the contribution of genomes, transcriptomes and proteomes in determining drug-response phenotypes (safety and efficacy). (bvsalud.org)

During a D-test, bacteria of the iMLSB phenotype demonstrate in vitro erythromycin-induced in vitro resistance to clindamycin. (wikipedia.org)
Whether these phenotype and resistances that had no fitness cost to the bacterium could significantly affect the virulence of the bacteria in vivo remains to be investigated. (scirp.org)
and Dr. Louise Francois Watkins, a Medical Officer, all with CDC's National Antimicrobial Resistance Monitoring System for Enteric Bacteria Team within the National Center for Emerging and Zoonotic Infectious Diseases. (cdc.gov)
ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections. (goldbio.com)
They also analyzed clinical isolates from patients who had been on the ward prior to refurbishment and were known to be colonized with antibiotic-resistant bacteria. (umn.edu)
In theory, the extent of fitness costs determines the long-term stability of resistance, and consequently, the rate by which the frequency of resistant bacteria decreases in an antibiotic-free environment. (elifesciences.org)
Antimicrobial resistance is a global challenge and food animal production, including cattle production, is increasingly singled‐out as a significant contributor to emergence, amplification, persistence and dissemination of antimicrobial‐resistant bacteria. (beefresearch.org)
This is likely to happen eventually, but the rate of decline is a function of the fitness cost that is incurred by the bacteria for carrying resistance traits. (beefresearch.org)
The fitness cost will make the bacteria less competitive so that the bacteria will rapidly diminish in prevalence, or they will shed the resistance trait. (beefresearch.org)

Since these organisms require highly specialized conditions for culture in vitro and because molecular-based detection is not widely available (except for M genitalium), clinicians must be aware of the clinical syndromes with which these organisms have been associated and have a high level of suspicion prompting them to order the appropriate diagnostic tests from reference laboratories. (medscape.com)
This study compared the in vitro efficacy of furazolidone with metronidazole, clarithromycin, amoxicillin and tetracycline in 70 H. pylori isolates from dyspeptic patients. (who.int)

One isolate was resistant to cefixime, but no resistance to ceftriaxone or spectinomycin was found. (biomedcentral.com)

Different types of antibiotic resistance mechanisms have been found in S. aureus that beta-lactamase producing is the most common which associated gene with enzyme production is located on the plasmid. (alliedacademies.org)

RESULTS: Resistance to ß-lactams, fluoroquinolones, tetracyclines and aminoglycosides was frequent. (bvsalud.org)

Umar, U. , Anagor, S. , Aliyu, A. and Suleiman, A. (2016) Hypermucoviscosity in Clinical Isolates of Klebsiella pneumoniae Correlates with High Multiple Antibiotic Resistance (MAR) Index. (scirp.org)

Resistance is conferred through active efflux, protection of ribosomes, or tetracycline inactivation. (goldbio.com)
Tetracycline efflux pumps are of particular interest because of their broad global distribution and because they are regulated so that their expression only occurs in the presence of tetracycline or a tetracycline analogue. (beefresearch.org)
For the current proposal we developed a means to induce expression of tetracycline efflux pumps. (beefresearch.org)
Presence of Efflux Pump may not be associated with resistance. (cdc.gov)

The aim of current study is detection of clindamycin inductive resistance S. aureus isolates among patients admitted to Tehran hospitals by multiplex PCR. (alliedacademies.org)
Nowadays, antibiotic resistance of S. aureus is a major problem in society [ 4 ]. (alliedacademies.org)
There were difficulties with E. coli and mecillinam, and S. aureus and tetracycline and rifampicin. (lu.se)

However, in other cases, such deleterious side effects of resistance mutations are undetectable, and resistance can even confer benefits in specific, antibiotic-free environmental settings ( Maharjan and Ferenci, 2017 ). (elifesciences.org)
El objetivo de este trabajo fue generar información sobre los serotipos circulantes, resistencia a los antibióticos y presencia de resistencia simultánea a múltiples fármacos en Salmonella provenientes de muestras clínicas humanas y muestras de alimentos en el periodo desde 2017 a 2019. (bvsalud.org)
Fueron analizadas un total de 668 cepas de Salmonella aisladas en los años 2017, 2018 y 2019 a partir de muestras clínicas humanas y de alimentos, en el Laboratorio Central de Salud Pública y/o remitidas por Laboratorios de la Red de Enteropatógenos. (bvsalud.org)
The target of this work was to generate information on circulating serotypes, antibiotic resistance and the presence of simultaneous resistance to multiple drugs in Salmonella from human clinical samples and food samples in the period from 2017 to 2019. (bvsalud.org)

Onyango D, Machioni F, Kakai R, Waindi EN (2008) Multidrug resistance of Salmonella enterica serovars Typhi and Typhimurium isolated from clinical samples at two rural hospitals in Western Kenya. (jidc.org)
Conclusions and Clinical Relevance -The prevalence of multidrug resistance was comparable for virulent and avirulent E coli isolated from diarrheic neonatal calves. (avma.org)
and (2) Conduct a clinical trial to determine if feeding calves the tetracycline inducer will reduce the proportion of tetracycline and multidrug resistant E . coli in cattle feces. (beefresearch.org)

Antimicrobial resistance profiles in Escherichia coli O157 isolates from northern Colorado dairies. (cdc.gov)

Resistance was tentatively set at below 3 SD from the calculated, ideal mean zone diameter of the susceptible population. (lu.se)

Vibramycin I.V. ( doxycycline hyclate) is a tetracycline antibiotic used to treat many different bacterial infections such as urinary tract infections acne gonorrhea and chlamydia periodontitis (gum disease) and others. (rxlist.com)
In this paper, we demonstrated that the combination of a farnesyl spermine compound 3 used at concentrations ranging from 2.5 to 10 µM, in the presence of doxycycline or minocycline leads to a significant decrease of P. aeruginosa antibiotic resistance. (hal.science)

Conclusions and Clinical Relevance -Results suggest that estimates of E coli O157 prevalence derived from sampling of 1 location/pat are likely underestimates of the true prevalence of this pathogen in fecal pats (and by extension, cattle). (avma.org)

Tetracyclines are not the drugs of choice in the treatment of any type of staphylococcal infections. (rxlist.com)
Antimicrobial resistance (AMR) is a complex phenomenon that complicates the treatment of serious bacterial infections and is of increasing concern. (cdc.gov)

the highest prevalence of resistance was recorded for the macrolide-lincosides, followed by the tetracyclines and penicillins. (avma.org)
Tetracyclines may interfere with the bactericidal action of penicillins. (medscape.com)
Monitor for decreased therapeutic effects of penicillins if concomitantly used with a tetracycline. (medscape.com)

Clindamycin inductive resistance causes failure in treatment. (alliedacademies.org)
The identification of clindamycin inductive resistance isolates was performed by D-zone test. (alliedacademies.org)
In current experiment, among 80 isolates, resistance rate to erythromycin and clindamycin were 70% and 45% respectively. (alliedacademies.org)

Oxytetracycline has been used to study its resistance gene, otrA and in fluorescence analysis of liver cells. (goldbio.com)
Methods: The clinical isolates of Streptococcus gallolyticus were identified by using conventional biochemical tests, PCR, and sodA gene sequence analysis. (clin-lab-publications.com)
This analysis does not include mutations that may result in antibiotic resistance or resistance determinants added to newer versions of used database or other antimicrobial resistance gene databases. (cdc.gov)
A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa. (ox.ac.uk)

Resistance to furazolidone, trimethoprim-sulfamethoxazole and erythromycin was 100%, 98% and 62% respectively. (who.int)

Results of animal studies indicate that tetracyclines cross the placenta and are found in fetal tissues. (nih.gov)

Klebsiella spp and Citrobacter spp showed resistance to mint and lemongrass oil respectively. (scielo.br)

The tetracyclines are primarily bacteriostatic and are thought to exert their antimicrobial effect by the inhibition of protein synthesis. (nih.gov)

1 Therefore, it is crucial for dermatologists to understand strategies to combat bacterial resistance and reduce its global burden. (skintherapyletter.com)
When using CILOXAN eye drops one should take into account the risk of rhinopharyngeal passage which can contribute to the occurrence and the diffusion of bacterial resistance. (medicines.org.uk)
The increase in bacterial resistance constitutes a threat to public health. (bvsalud.org)

General methods for diminishing risk of antibiotic resistance include detailed history and physical, diagnostic laboratory and culture studies, close monitoring of clinical response, appropriate directed-therapy when the causative organism is identified, relevant empiric treatment based on local antimicrobial susceptibilities within the community, and continuing therapy for the appropriate duration. (skintherapyletter.com)

Both topical and systemic monotherapy may induce resistance among Cutibacterium acnes (C. acnes) and other organisms that comprise the commensal and transient flora. (skintherapyletter.com)

Conclusions The normalized resistance interpretation offers a new approach to comparative surveillance studies whereby the inhibition zone diameter results from disk tests in clinical laboratories can be used for calibration of the test. (lu.se)

OBJECTIVES: We reported tet(S/M) in Streptococcus pneumoniae and investigated its temporal spread in relation to nationwide clinical interventions. (ox.ac.uk)

Brucella bacteraemia: clinical and laboratory observations in 160 patients. (qxmd.com)
Additionally, the influence of covariates, such as body surface area, severity of illness, and clinical laboratory measures, on tigecycline disposition was evaluated. (druglib.com)

The tetracyclines, including minocycline, have similar antimicrobial spectra of activity against a wide range of gram-positive and gram-negative organisms. (nih.gov)
Cross-resistance of these organisms to tetracyclines is common. (nih.gov)
These may include harms to individuals taking Doxy-PEP, such as disruptions to their microbiome and increased antimicrobial resistance (AMR) in STIs and other organisms, and harms to the community through increased population-level AMR. (ashm.org.au)

Oxytetracycline is a tetracycline antibiotic derived from Streptomyces rimosus . (goldbio.com)

ABSTRACT An analytical cross-sectional study determined the serogroups and serotypes of Vibrio cholerae , and their antibiotic resistance rates, in the 2005 cholera epidemic in Hamadan. (who.int)

It also reviews the way drug resistance develops and spreads, methods used to assess the presence and level of drug resistance, and the extent to which chloroquine and sulfadoxine/pyrimethamine (SP)-the two most widely used antimalarial drugs in the world today-have now lost efficacy. (nationalacademies.org)
5 Clinical and PK/PD data demonstrate colistin has limited clinical efficacy, even if an intermediate result is obtained. (cdc.gov)

Resistance to nafcillin, methicillin and oxacillin is independent from betalactamase producing [ 7 , 8 ]. (alliedacademies.org)

Feeding our inducer tetracycline resistance to dairy calves produced mixed results, but this has led to several additional ideas for developing this strategy. (beefresearch.org)

Under this scenario we would target a highly prevalent antibiotic resistance trait and artificially induce a fitness cost on the host bacterium as the "price" for harboring the resistance trait. (beefresearch.org)

Once the prevalence of resistance has increased to a clinically relevant level, however, it is unclear how effective prudent use and regulatory control practices will be in the short‐term. (beefresearch.org)

Recently, we demonstrated that combination of a tetracycline antibiotic with various polyaminoisoprenyl adjuvants can sustain the life span and enhance the activity of these drugs against Pseudomonas aeruginosa reference strain (PA01). (hal.science)
N. gonorrhoeae has developed antimicrobial resistance (AMR) to all drugs previously recommended for treatment of gonorrhoea. (biomedcentral.com)

Anatomy4

Organisms39

Diseases8

Chemicals and Drugs37

Analytical, Diagnostic and Therapeutic Techniques and Equipment18

Phenomena and Processes46

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture3

Information Science4

Health Care1

Geographicals2

Antibiotics29

Ampicillin5

Genes12

Penicillin7

Strains16

Macrolides2

Streptomycin2

Susceptibility6

Ciprofloxacin1

Antimicrobials4

Microbiology1

PHARMACOLOGY1

Bacteria9

Vitro2

Ceftriaxone1

Mechanisms1

Aminoglycosides1

Multiple Antibiotic Resistance1

Efflux4

Aureus3

20174

Multidrug3

Escherichia1

Susceptible1

Doxycycline2

Coli1

Infections2

Penicillins3

Clindamycin3

Gene4

Trimethoprim1

Placenta1

Klebsiella1

Protein1

Bacterial resistance3

Susceptibilities1

Systemic1

Conclusions1

Streptococcus1

Laboratory2

Organisms3

Oxytetracycline1

Abstract1

Efficacy2

Methicillin1

Calves1

Induce1

Prevalence1

Drugs2