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  • 1999
  • 1999-06-09T12:00:00Keystats is a Data Analytics download Genomics and Clinical Medicine 2008 polarization opting in consulting tumors improved vehicles to areas across available movements. (intervista-institute.com)
  • Serum
  • The parent camptothecin molecule is compromised in its clinical utility by several factors: it is poorly water soluble ( 2 ), and it undergoes conversion at physiologic pH to the inactive carboxylate form ( 3 ) of the drug, which binds avidly to human serum albumin ( 3 - 5 ). (aacrjournals.org)
  • cups
  • A programme to gamma-crosslink pre-manufactured polyethylene cups was undertaken under the expert guidance of the third author. (scielo.org.za)
  • Bjerkholt H, Høvik O, Reikerås O (2010) Direct comparison of polyethylene wear in cemented and uncemented acetabular cups. (springer.com)
  • Digas G, Kärrholm J, Thanner J (2006) Different loss of BMD using uncemented press-fit and whole polyethylene cups fixed with cement repeated DXA studies in 96 hips randomized to 3 types of fixation. (springer.com)
  • anhydride
  • Mice were immunized with OVA, poly(anhydride) NPs, and OVA plus NP and 8 days after immunization sacrificed. (asm.org)
  • The mechanisms that underlie the potent Th1-adjuvant capacity of poly(methyl vinyl ether-co-maleic anhydride) nanoparticles (NPs) were investigated. (asm.org)
  • Poly(anhydride) NPs made by the copolymer of methyl vinyl ether and maleic anhydride have demonstrated their efficacy as adjuvants in inducing Th1 immune responses ( 16 , 17 , 47 - 49 ). (asm.org)
  • Poly(anhydride) NPs are actually licensed in the United Kingdom for oral drug delivery ( 46 ) and have proven adjuvant capacities in mentioned and other routes. (asm.org)
  • efficacy
  • Dr. S.F. Khuri of Harvard Medical School presented the results of a blinded, randomized, placebo-controlled clinical trial to evaluate the efficacy of the SyvekPatch in improving hemostasis in patients undergoing cardiac catheterization. (cathlabdigest.com)
  • disease
  • Materials and Methods In this cross-sectional study, clinical aspects of disease, history of arthritis and autoantibody profiles were obtained from 106 consecutive patients with definite diagnosis of IIM. (bmj.com)
  • patients
  • Performance of the hepatic encephalopathy scoring algorithm in a clinical trial of patients with cirrhosis and severe hepatic encephalopathy. (jamanetwork.com)
  • Background and Objectives Arthritis in idiopathic inflammatory myopathies (IIM) is frequently observed in clinical practise, but, to our knowledge, there is lack of systemic reports of prevalence and/or characteristics of arthritis in myositis patients. (bmj.com)
  • 52 patients presented arthritis at clinical examination (25 poly-, 17 oligo-, and 10 with monoarthritis). (bmj.com)
  • PARP
  • All PARP family members are characterized by the ability to poly(ADP-ribosyl)ate protein substrates and all share a catalytic PARP homology domain ( 1 ). (aacrjournals.org)
  • The functions of other PARP family members remain to be elucidated, but poly(ADP-ribosyl)ation has been implicated in many cellular processes, including differentiation, gene regulation, protein degradation, spindle maintenance, as well as replication and transcription ( 6 ). (aacrjournals.org)
  • survival
  • Secondary aims include the gathering of clinical data regarding survival and dislocation rates at two years post surgery, as well as the assessment of pain, physical function, radiographic and clinical outcome at the two year interval. (clinicaltrials.gov)
  • proteins
  • Poly(lactic-co-glycolic acid) (PLGA) microspheres have been used as a controlled delivery system of many proteins, drugs, and others factors, such as cytokines, hormones, enzymes, vaccines, and chemotherapeutic agents (14-19) . (aacrjournals.org)
  • years
  • BIOLOX ® delta is the only ceramic with 14 years of successful clinical experience and with more than seven million sold components. (ceramtec.com)
  • Barrack RL, Folgueras A, Munn B, Tvetden D, Sharkey P (1997) Pelvic lysis and polyethylene wear at 5-8 years in a uncemented total hip. (springer.com)
  • Study
  • Names inside the bars of positive controls represent the specific agonist for each TLR used in the study: PAM2 (100 ng/ml) for TLR2, poly(I:C) (100 ng/ml) for TLR3, E. coli K12 LPS (1 μg/ml) for TLR4, flagellin (1 μg/ml) for TLR5, R848 (10 μg/ml) for TLR7 and TLR8, and ODN 2006 (10 μg) for TLR9. (asm.org)
  • despite
  • 1 In spite of the worthiness of the goal, however, no product is currently approved for clinical use despite a large amount of research and development by both industry and academia. (asahq.org)
  • effect
  • In addition, poly- l -glutamate is postulated to increase tumor delivery of the active compound through enhanced permeability and retention effect in tumor. (aacrjournals.org)
  • CT-2106, a poly- l -glutamic acid-glycine-camptothecin conjugate, has the potential to deliver higher active camptothecin doses to tumor tissue compared with normal tissues, thereby reducing toxicity due to the enhanced permeability and retention effect of the poly-glutamate backbone. (aacrjournals.org)
  • year
  • It was concluded that there was an almost seven to eight times improvement in the polyethylene cup wear, from the international figure of ± 0.1mm per year down to 0.015 mm per year. (scielo.org.za)
  • made
  • Polymeric microspheres made of poly(lactic-co-glycolic acid) (PLGA) were loaded with very low amounts of PEX and PF-4/CTF. (aacrjournals.org)