Clinical pneumonia pneumococcal. Medical search. Frequent questions

Pneumococcal infections are globally the most frequent vaccine-preventable cause of death [ 1 ], and community-acquired pneumonia (CAP) caused by Streptococcus pneumoniae is the main burden of pneumococcal disease in the elderly [ 2 ]. (ersjournals.com)
Community-acquired pneumonia (CAP) refers to pneumonia (any of several lung diseases) contracted by a person outside of the healthcare system. (wikipedia.org)
Occupational exposure to gases, fumes, or chemicals and risk of community-acquired pneumonia. (cdc.gov)
Prevention of community-acquired pneumonia among a cohort of hospitalized elderly: Benefit due to influenza and pneumococcal vaccination not demonstrated. (edu.au)
Childhood community-acquired pneumonia is most often attributed to Streptococcus pneumoniae , and the greatest incidence of invasive pneumococcal infection (IPD) is observed in children younger than age 2 [ 4 ]. (biomedcentral.com)
In addition, growing prevalence of community-acquired pneumonia, especially in younger individuals, is also a key factor contributing to market growth. (grandviewresearch.com)
Community-acquired pneumonia (CAP) in the elderly has increased as a consequence of an overall increase of the elderly population. (ersjournals.com)
The results of this study may aid in the management of empiric antibiotic treatment in elderly patients with community-acquired pneumonia and the patients who have a greater probability of bad evolution may be identified based on the risk factors. (ersjournals.com)
Community-acquired pneumonia (CAP) is a relatively frequent infectious disease with an incidence that ranges from 3-6 cases per 1,000 inhabitants per year 1 . (ersjournals.com)
Two isolates of streptococcus pneumoniae having different optochin susceptibilities were recovered from a blood sample of a 2-year-old boy with community-acquired pneumonia. (lookfordiagnosis.com)
Some studies have shown a beneficial effect of corticosteroids in patients with community-acquired pneumonia (CAP), possibly by diminishing local and systemic antiinflammatory host response. (atsjournals.org)
Disease severity was scored using CURB-65 (a severity index for community-acquired pneumonia evaluating Confusion, blood Urea nitrogen, Respiratory rate, Blood pressure, and age 65 or older) and Pneumonia Severity Index. (atsjournals.org)
The use of corticosteroids along with antibiotics in patients with community-acquired pneumonia (CAP) may lead to a diminished local and systemic antiinflammatory response. (atsjournals.org)
Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide ( 1 ). (atsjournals.org)
We used laboratory data for invasive pneumococcal disease (IPD) and coded hospitalizations for noninvasive pneumococcal community-acquired pneumonia (PnCAP) to evaluate long-term impact. (edu.au)
Fifteen years after pneumococcal conjugate vaccine (PCV) introduction and 5 years post-PCV13, direct and indirect impact on invasive pneumococcal disease and pneumococcal community-acquired pneumonia differed by age and between Indigenous and non-Indigenous people, with potential implications for long-term PCV impact in comparable settings. (edu.au)
Age younger than 65 years, hypoalbuminemia, a need for intensive respiratory or vasopressor support (IRVS), and high serum C-reactive protein (CRP) levels are independent risk factors for the development of bacteremia in patients with pneumococcal community-acquired pneumonia (CAP), according to an article published in BMC Pulmonary Medicine . (infectiousdiseaseadvisor.com)
Community-acquired pneumonia (CAP) is a serious disease, most frequently caused by Streptococcus pneumonia [ 1 ]. (biomedcentral.com)
Pneumonia is classified into community-acquired pneumonia (CAP), hospital-acquired pneumonia (HAP) and pneumonia in the immunocompromised. (bvsalud.org)

The decline in the proportion of pneumococcal conjugate vaccine (PCV)-covered serotypes among adult invasive adults, it is a public health concern, particularly in pneumococcal disease (IPD) patients might change the countries with aging populations, such as Japan ( 3 , 4 ). (cdc.gov)
Two types of pneumococcal vaccines are cur- polysaccharide vaccine (PPSV23) because its effective- rently available for adults: the 23-valent pneumo- ness differs according to serotype. (cdc.gov)
13-valent pneumococcal conjugate vaccine (PCV13). (cdc.gov)
Pneumococcal Polysaccharide Vaccine, Japan decline might have changed the effectiveness of microbiologic testing results were available were in- PPSV23 against PPSV23-serotype IPD. (cdc.gov)
In June 2022, the Food and Drug Administration approved an expanded usage of 15-valent pneumococcal conjugate vaccine (PCV15 [Merck Sharp & Dohme LLC]) to include children. (cdc.gov)
For Germany, we have described earlier the distribution of vaccine serotypes covered by the first but no longer available 7-valent pneumococcal conjugate vaccine (PCV7) and the 13-valent conjugate vaccine (PCV13) between 2002 and 2016 in adult patients with CAP enrolled into the prospective multicentre study CAPNETZ [ 8 , 9 ]. (ersjournals.com)
In adults, the German Standing Committee on Immunization (STIKO) recommends the 23-valent pneumococcal polysaccharide vaccine (PPV23) as routine pneumococcal vaccination for all adults of 60 years and above and for all patients with defined chronic comorbidities predisposing to pneumococcal disease, regardless of age. (ersjournals.com)
This report updates the last recommendations by the Advisory Committee on Immunization Practices (ACIP) concerning pneumococcal polysaccharide vaccine (MMWR 1989;38:64-8,73-6). (cdc.gov)
This report contains updated information regarding a) antimicrobial resistance among pneumococci, b) vaccine effectiveness and cost-effectiveness, c) indications for vaccination, d) guidelines for revaccination, e) strategies for improving delivery of vaccine, and f) development of pneumococcal conjugate vaccine. (cdc.gov)
The focus of this report is the prevention of invasive pneumococcal disease (i.e., bacteremia, meningitis, or infection of other normally sterile sites) through the use of pneumococcal polysaccharide vaccine. (cdc.gov)
This vaccine protects against invasive bacteremic disease, although existing data suggest that it is less effective in protecting against other types of pneumococcal infections. (cdc.gov)
Pneumonia pre-vaccine and pre-antibiotics was famously called the "Captain of the Men of Death" after consumption. (medscape.com)
Before 2021, ACIP recommended 23-valent pneumococcal polysaccharide vaccine (PPSV23) alone (up to 2 doses), or both a single dose of 13-valent pneumococcal conjugate vaccine (PCV13) in combination with 1-3 doses of PPSV23 in series (PCV13 followed by PPSV23), for use in U.S. adults depending on age and underlying risk for pneumococcal disease. (cdc.gov)
In addition, ACIP recommends use of either a single dose of PCV20 or ≥1 dose of PPSV23 for adults who have started their pneumococcal vaccine series with PCV13 but have not received all recommended PPSV23 doses. (cdc.gov)
Shared clinical decision-making is recommended regarding use of a supplemental PCV20 dose for adults aged ≥65 years who have completed their recommended vaccine series with both PCV13 and PPSV23. (cdc.gov)
During 2018-2019, approximately 60%-75% of all IPD in adults was caused by the 24 pneumococcal serotypes that were included in the formulations of commercially available polysaccharide conjugate vaccine (PCV) or pneumococcal polysaccharide vaccine (PPSV) vaccines (i.e. (cdc.gov)
Since 2007, the World Health Organization (WHO) has recommended using pneumococcal conjugate vaccine (PCV) in childhood immunization programs. (cdc.gov)
Clinical observations support the epidemiological and experimental studies, in that workers with occupational lung disease often present with pneumonia and because of this it has been routine practice for years to provide pneumococcal and influenza vaccine to workers with occupational lung diseases. (cdc.gov)
Pneumococcal Polysaccharide Vaccine May Not Prevent Hospitalization for Pneumonia in Elderly Individuals. (edu.au)
Pneumococcal conjugate vaccine (PCV) reduces both invasive pneumococcal disease (IPD) and other pneumococcal infections worldwide. (biomedcentral.com)
Serotype 19A was the major serotype for all vaccine types in patients with pneumococcal pneumonia and severity of acute inflammatory response was reduced in vaccinated patients. (biomedcentral.com)
Pfizer Inc. (NYSE:PFE) today announced that the U.S. Food and Drug Administration (FDA) accepted for priority review a Biologics License Application (BLA) for its 20-valent pneumococcal conjugate vaccine (20vPnC) candidate, as submitted for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae serotypes in the vaccine in adults ages 18 years and older. (pfizer.com)
The FDA's acceptance of our application for 20vPnC is yet another significant milestone in Pfizer's continuing efforts to help protect adults against pneumococcal disease," said Kathrin U. Jansen, Ph.D., Senior Vice President and Head of Vaccine Research and Development, Pfizer. (pfizer.com)
If approved, 20vPnC will cover more serotypes responsible for the majority of pneumococcal disease than any other pneumococcal conjugate vaccine currently licensed or currently in late-stage clinical development. (pfizer.com)
Pneumococcal Vaccine clinical trials, like those at CNS Healthcare, can help you explore new vaccine options. (cnshealthcare.com)
Interested in trying a new pneumococcal vaccine at no cost? (cnshealthcare.com)
Find out more about enrolling pneumococcal vaccine clinical trials available by selecting one of the below locations near you. (cnshealthcare.com)
Use the form on the page to schedule a free, in-office consultation to find out if a pneumococcal vaccine trial is right for you. (cnshealthcare.com)
with risk conditions who have not previously received a pneumococcal conjugate vaccine or whose previous vaccination history is unknown. (pharmashots.com)
Children with complete immunization coverage received at least three doses of pneumococcal and anti Haemophilus influenzae vaccine and two doses of measles vaccine. (scirp.org)
Background Universal pneumococcal conjugate vaccine (PCV) programs began in Indigenous Australian children in 2001 and all children in 2005, changing to 13-valent PCV (PCV13) in 2011. (edu.au)
Researchers plan to see if a higher dose of a pneumococcal vaccine will create a stronger immune response in older adults who received an earlier generation vaccine against pneumonia and other pneumococcal diseases. (nih.gov)
The study supported by the National Institutes of Health will compare two dosages of a pneumococcal vaccine approved for children ages 6 weeks to 5 years, and adults 50 and older. (nih.gov)
For the past 30 years, the PPSV23 vaccine (23-valent pneumococcal polysaccharide vaccine), known by the brand name Pneumovax 23, has been the standard protection from invasive pneumococcal disease in adults over 65 years of age. (nih.gov)
While this vaccine protects against pneumococcal meningitis and bloodstream infections, it is unclear how well it protects against bacterial pneumococcal pneumonia. (nih.gov)
The newer PCV13 vaccine (13-valent pneumococcal conjugate vaccine), known by the brand name Prevnar 13, protects against bacterial pneumonia and other invasive pneumococcal illnesses in children, but the efficacy and most effective dosage in adults is unknown. (nih.gov)
One of the most promising candidates is the Whole-Cell Pneumococcal Vaccine (WCV). (mdpi.com)
Clinical presentations and serotypes causing invasive pneumococcal disease in adults vaccinated with the 23-valent polysaccharide pneumococcal vaccine (PPV23) in Spain. (ers-education.org)
Impaired response to 13-valent pneumococcal conjugate vaccine (PCV13) in children with recurrent respiratory infections and chronic cough. (ers-education.org)
KENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of VAXNEUVANCE™ (Pneumococcal 15-valent Conjugate Vaccine) for active immunization for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae in individuals 18 years of age and older. (merck.com)
The 23-valent pneumococcal polysaccharide vaccine (PPV23) has been recommended to risk-groups and adults aged ≥65 years since 1996. (biomedcentral.com)
The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in the childhood immunization program in July 2006, and was replaced by the 13-valent vaccine (PCV13) in 2011. (biomedcentral.com)
Objective: To estimate the increase in the costs of the National Immunization Program due to the introduction of the pneumococcal vaccine candidate. (bvsalud.org)
Vaccination with a 23-valent pneumococcal polysaccharide vaccine (23vPPV) induces antibody production against the external polysaccharide capsule of the pneumococcus [ 3 ]. (biomedcentral.com)
Results from a Phase 2 clinical study of a pentavalent meningococcal meningitis vaccine designed for use in the African meningitis belt demonstrate the vaccine candidate to be safe, well-tolerated, and capable of producing strong immune responses to all five serogroups. (path.org)
PATH and its partners have been conducting clinical trials to evaluate a pneumococcal vaccine designed to meet needs in low-resource countries. (path.org)
On October 19, 2022, the U.S. Advisory Committee on Immunization Practices (ACIP) recommended the use of either a dose of 20-valent pneumococcal conjugate vaccine (PCV20) or 23-valent pneumococcal polysaccharide vaccine (PPSV23) as previously recommended for adults who have received 13-valent pneumococca. (bvsalud.org)
GRADE was used to evaluate 13-valent Pneumococcal Conjugate Vaccine (PCV13) for routine use among immunocompromised children aged 6 through 18 years. (bvsalud.org)
GRADE was used to evaluate 13-valent Pneumococcal Conjugate Vaccine (PCV13) and 23-valent pneumococcal polysaccharide vaccine (PPSV23) for routine use among immunocompromised adults. (bvsalud.org)
The 13-va- lent pneumococcal conjugate vaccine (PCV) was introduced to the Moroccan National Immunization Programme in 2010. (who.int)

When a suspension of pneumococcal colonies are treated with a loop of serum containing anitbodies to capsular polysaccharide and observed under microscope, the capsule appears swollen. (microrao.com)
Dot-enzyme-linked immunosorbent assay (Dot-ELISA) for detection of pneumococcal polysaccharide antigens in pleural fluid effusion samples. (scielo.br)
Comparison with bacterial culture, counterimmunoelectrophoresis and latex agglutination Dot-enzyme-linked immunosorbent assay (Dot-ELISA) for detection of pneumococcal polysaccharide antigens in pleural fluid effusion samples. (scielo.br)
Patients with recurrent respiratory tract infections and an impaired response to pneumococcal polysaccharide vaccination are diagnosed with a specific antibody deficiency. (biomedcentral.com)
It is unknown whether these patients are unable to produce an adequate anti-polysaccharide antibody response to pneumococcal vaccination after recovery. (biomedcentral.com)
After pneumococcal polysaccharide vaccination 3 months after recovery, she responded adequately to most other pneumococcal serotypes, but still had no response to the infecting serotype 9V. (biomedcentral.com)
An impaired response to pneumococcal polysaccharide vaccination can be a risk factor for recurrent respiratory tract infections [ 4 ]. (biomedcentral.com)
After recovery, an assessment of the humoral immune status was made, including analysis of the antibody response to pneumococcal polysaccharide vaccination. (biomedcentral.com)

In many whereas invasive pneumococcal disease (IPD), in- countries, the proportion of PCV-covered serotypes cluding meningitis and bacteremia, has severe clinical among adult IPD patients has been decreasing since manifestations with a high case-fatality ratio ( 2 ). (cdc.gov)
9.3% with pneumococcal AOM had PCV13+6C type and 8.2% had 2 additional serotypes included in PCV15 (3). (cdc.gov)
At least 100 pneumococcal serotypes were documented as of 2020 ( 5 - 7 ). (cdc.gov)
We investigated the impact of stepwise implementation of childhood PCV programs on the prevalence of pneumococcal pneumonia, severity of acute inflammation, and associations between breakthrough pneumonia and pneumococcal serotypes in Taiwan. (biomedcentral.com)
However, neutrophils of older pneumonia patients produced high levels of ROS to all three serotypes but had impaired NET release. (bham.ac.uk)

Each year in the United States, pneumococcal disease accounts for an estimated 3,000 cases of meningitis, 50,000 cases of bacteremia, 500,000 cases of pneumonia, and 7 million cases of otitis media (1-4). (cdc.gov)
examples of noninvasive disease include pneumonia without bacteremia, sinusitis, or otitis media. (cdc.gov)
Pneumococcal bacteremia is a blood infection. (cnshealthcare.com)
Using logistic regression models, Yasuyoshi Washio of the department of respiratory medicine at Saiseikai Fukuoka General Hospital, Fukuoka, Japan, and colleagues retrospectively analyzed data from 389 patients hospitalized with pneumococcal CAP between April 2007 and August 2015 at Kurashiki Central Hospital, Okayama, Japan, to determine risk factors for pneumococcal bacteremia . (infectiousdiseaseadvisor.com)
20 mg/dL as independent risk factors for the development of pneumococcal bacteremia. (infectiousdiseaseadvisor.com)
Washio Y, Ito A, Kumagai S, Ishida T, Yamazaki A. A model for predicting bacteremia in patients with community-acquired pneumococcal pneumonia: a retrospective observational study . (infectiousdiseaseadvisor.com)
Pneumococci may cause many clinical syndromes depending on the site of infection (e.g. otitis media, pneumonia, bacteremia, or meningitis). (cdc.gov)
For the purposes of national surveillance, "invasive" pneumococcal disease refers only to bacteremia and/or meningitis. (cdc.gov)

The ACIP Pneumococcal Vaccines Work Group employed the Evidence to Recommendation (EtR) framework, using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach, to guide its deliberations regarding use of PCV15 in U.S. children as an option for pneumococcal conjugate vaccination. (cdc.gov)
Pneumococcal conjugate vaccines (PCVs), which were primarily developed for vaccination of infants under 2 years of age, have significantly decreased invasive pneumococcal diseases worldwide in all age groups by herd protection effects [ 5 , 6 ]. (ersjournals.com)
Validity of self-reported influenza and pneumococcal vaccination status among a cohort of hospitalized elderly inpatients. (edu.au)
Systematic childhood pneumococcal vaccination reduced the prevalence of community-acquired pneumococcal pneumonia, especially in 2-5 year group. (biomedcentral.com)
Universal vaccination with PCV7 also resulted in a 77% reduction in pneumococcal disease in children aged 1-5 and a 39% reduction in hospitalization of children age under age 2 [ 3 ]. (biomedcentral.com)
Should PCV20 without PPSV23 be recommended as an option for pneumococcal vaccination for U.S. children aged 2-18 years with underlying medical conditions that increase the risk of pneumococcal disease? (cdc.gov)
The present data contribute to pneumococcal vaccination public health policies for vulnerable patients, mainly those with comorbidity and the elderly. (bvsalud.org)
The authors suggest that this may be because of poorer pneumococcal vaccination rates among younger patients in Japan. (infectiousdiseaseadvisor.com)
The study is limited by the inability to determine pneumococcal serotype or vaccination status and by its small size and retrospective design. (infectiousdiseaseadvisor.com)
However, after 9 years (and prior to pneumococcal-conjugate vaccination) normal antibody levels against 9V were found. (biomedcentral.com)
These antibody levels further increased after pneumococcal-conjugate vaccination. (biomedcentral.com)
HAART), Pneumocystis carinii pneumonia (PCP) prophylaxis, Mycobacterium avium complex (MAC) prophylaxis, and pneumococcal vaccination. (cdc.gov)

rates for meningitis and bacteremic pneumonia are eightfold to tenfold higher for Alaskan Natives of all ages than for other U.S. population groups (13). (cdc.gov)
Meningitis and pneumonia are leading causes of morbidity and mortality in children globally. (cdc.gov)
Pneumococcal vaccines can prevent some cases of pneumonia, meningitis, and sepsis. (cnshealthcare.com)
Pneumococcal meningitis is an infection of the tissue covering the brain and spinal cord. (cnshealthcare.com)
Streptococcus pneumoniae is a human pathogen that is responsible for causing pneumonia, otitis media, meningitis, and other infectious diseases. (mdpi.com)
IPD) such as meningitis, bacteremic pneumonia and sepsis, patients with IPD. (bvsalud.org)
and meningitis (infection of the coverings of the brain and spinal cord), as well as non-invasive pneumonia (when pneumococcal disease is confined to the lungs). (merck.com)

Use of PCVs (PCV7, PCV13) significantly decreased the incidence of pneumococcal disease in U.S. children. (cdc.gov)

It is a case of acute lower respiratory tract infection, probably lobar pneumonia. (microrao.com)
A common cause of sepsis is bacterial pneumonia, frequently the result of infection with streptococcus pneumoniae. (wikipedia.org)
Pneumonia is an infection in one or both of your lungs. (medlineplus.gov)
Overview of Pneumonia Pneumonia is acute inflammation of the lungs caused by infection. (msdmanuals.com)
Pneumococcal disease is an infection caused by the bacteria Streptococcus pneumoniae , or pneumococcus. (cnshealthcare.com)
Pneumococcal pneumonia (lung infection) is the most common serious form of pneumococcal disease. (cnshealthcare.com)
Increase in number of resistant strains and high rate of mortality & morbidity associated with pneumococcal infection have led to increased preference for prevention therapy. (grandviewresearch.com)
We describe the rare complication of necrotizing pneumonia and invasive pneumococcal infection in 3 previously healthy pediatric patients . (lookfordiagnosis.com)
The effect of age on neutrophil and monocyte responses to \(S.\) \(pneumoniae\) and on CD4+ T cell polarisation during health, pneumococcal carriage and clinical pneumonia infection were determined. (bham.ac.uk)
In conclusion, failure of pneumococcal carriage to generate immune memory, together with altered neutrophil responses to \(S.\) \(pneumoniae\) and high frequencies of inflammatory Th subsets in older adults who succumb to infection, could contribute to their increased susceptibility to pneumococcal infection. (bham.ac.uk)
As the most common health care-associated infection in the United States, hospital-acquired pneumonia is associated with high morbidity, mortality, and health care use. (pharmacytimes.com)
The global prevalence of pneumococcal disease, an infection caused by bacteria called Streptococcus pneumoniae , is evolving. (merck.com)
While healthy adults can suffer from pneumococcal disease, patient populations particularly vulnerable to infection include older adults such as those 65 years of age and older, people with HIV, and those with certain chronic health conditions. (merck.com)
This report describes case notification data for measles, pertussis, rubella, Haemophilus influenzae type b invasive infection, invasive meningococcal disease (IMD), mumps, tetanus and invasive pneumococcal disease (IPD) in NSW, Australia, in 2012 and provides comparison with recent trends. (who.int)

In Japan, PCV7 was licensed in November 2010, ens Serum Institute, https://en.ssi.dk) after culturing included in the routine immunization program for overnight. (cdc.gov)
This report compiles and summarizes all published recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of pneumococcal vaccines in adults aged ≥19 years in the United States. (cdc.gov)
81% of the sample reported not smoking at the time of the exam, only 38.2% reported ever having had a pneumococcal immunization, and 28.2% reported getting the recommended level of physical activity. (diabetesjournals.org)
This compendium of immunization recommendations for adults (≥18 years) with HIV was compiled by the New York State Department of Health AIDS Institute (NYSDOH AI) to assist clinical practitioners in New York State who provide primary care to adults with HIV. (hivguidelines.org)
In addition, in 2009, pneumococcal and haemophilus B vaccines were added in the Expanded Program on Immunization. (scirp.org)

In 2021, two new pneumococcal conjugate vaccines (PCVs), a 15-valent and a 20-valent PCV (PCV15 and PCV20), were licensed for use in U.S. adults aged ≥18 years by the Food and Drug Administration. (cdc.gov)
Although Pneumococcal Conjugate Vaccines (PCVs) are available and have significantly reduced the rate of invasive pneumococcal diseases, there is still a need for new vaccines with unlimited serotype coverage, long-lasting protection, and lower cost to be developed. (mdpi.com)

There is no pathognomonic feature of M. catarrhalis otitis media, acute or chronic sinusitis, or pneumonia. (msdmanuals.com)

CASE SUMMARY: A 34-year-old African-American man was admitted to the hospital for pneumococcal pneumonia and sepsis . (lookfordiagnosis.com)
Corticosteroids are used in patients with sepsis or septic shock, of which a large part is due to pneumonia. (atsjournals.org)
Invasive pneumococcal disease (IPD) and sepsis are responsible for substantial morbidity and mortality worldwide with about 2 million deaths each year [ 4 ]. (biomedcentral.com)

There are many types of pneumococcal disease. (cnshealthcare.com)

Updated and new clinical guidance for implementation from CDC includes the recommendation for use of PCV15 or PCV20 for adults who have received PPSV23 but have not received any PCV dose. (cdc.gov)

In a retrospective case companion study published in the American Journal of the Medical Sciences , the researchers reviewed data from 51 adults with LD and 55 with bacteremic S. pneumoniae pneumonia (SP) who were hospitalized at a single center between 2013 and 2018. (medscape.com)
Pneumonia can be caused by bacteria such as Streptococcus pneumoniae (pneumococcus), Hemophilus influenzae, Klebsiella pneumoniae, Staphylococcus aureus. (microrao.com)
Mycoplasma pneumoniae is known to cause primary atypical pneumonia. (microrao.com)
Although children older than one month tend to be at risk for the same microorganisms as adults, children under five years of age are much less likely to have pneumonia caused by Mycoplasma pneumoniae, Chlamydophila pneumoniae or Legionella pneumophila than older children. (wikipedia.org)
ABSTRACT Susceptibility of 88 clinical Streptococcus pneumoniae isolates, 116 Haemophilus influenzae isolates and 80 Moraxella catarrhalis isolates to 6 fluoroquinolones--ciprofloxacin, ofloxacin, levofloxacin, trovafloxacin, grepafloxacin and gemifloxacin--were determined. (who.int)
Pneumococcal infections are caused by Streptococcus pneumoniae (pneumococcus), a gram-positive, facultative anaerobic bacterium. (cdc.gov)
The bacterium Streptococcus pneumoniae can cause a type of pneumonia called pneumococcal pneumonia. (nih.gov)
The authors describe a case of invasive pneumonia caused by Streptococcus pneumoniae serotype 9V in a previously healthy 35-year-old female. (biomedcentral.com)
ALRI is caused by a number of infective agents, have also shown a reduction in invasive pneumococcal with Streptococcus pneumoniae being the most frequently diseases after introduction of PCV ( 7 , 8 ). (who.int)

This paper describes the value in diagnosis and the clinical implications of the detection of pneumococcal antigen in patients with lobar pneumonia. (bmj.com)
Pneumococcal omniserum proved to be an optimal polyvalent antiserum for the detection of pneumococcal antigen by Dot-ELISA. (scielo.br)

Se trabajó con 132 pacientes hospitalizados en el Hospital Pediátrico de Cienfuegos entre septiembre de 2019 y febrero de 2020 con gastroenteritis y test rápido de rotavirus positivo. (bvsalud.org)

Pneumococcal antigen in lobar pneumonia. (bmj.com)
Ninety-eight patients with lobar pneumonia were investigated. (bmj.com)
He experienced a lobar pneumonia and developed an acute and persistent cerebellar deterioration which was most likely due to lithium toxicity, while the serum lithium level was within the therapeutic range. (lookfordiagnosis.com)
Managing the nonsurgical candidate with an empyema related to community-acquired lobar pneumonia. (lookfordiagnosis.com)

As the PUAT does not allow serotype discrimination, data on serotype distribution in adult non-bacteraemic pneumococcal CAP patients are sparse [ 4 ]. (ersjournals.com)
Current pneumococcal vaccines use the pneumococcal capsular polysaccharides as antigens to generate serotype-specific antibodies, which facilitate serotype-specific clearance of pneumococci through opsonophagocytosis ( 4 ). (cdc.gov)
In adult patients with pneumococcal pneumonia an impaired antibody response to the infecting pneumococcal serotype can sometimes be found. (biomedcentral.com)
The authors believe that this case is the first description of a temporary deficient response to the infecting pneumococcal serotype in adults, while other reports with similar observations all involved children. (biomedcentral.com)
This case report describes a patient with pneumococcal pneumonia in whom the infecting serotype was identified. (biomedcentral.com)

CAP, the most common type of pneumonia, is a leading cause of illness and death worldwide[citation needed]. (wikipedia.org)

Even in the past 3 years with the COVID-19 pandemic, where most of the pneumonia we saw was really viral driven and then with the respiratory syncytial virus (RSV) surge that we experienced just a few months ago, we saw some really bad cases of pneumonia. (medscape.com)
We saw some very severe cases of pneumonia with kids being in the intensive care unit and needing a lot of respiratory support and lot of other things to care for them. (medscape.com)

Pneumonia is the most might vary on the basis of the distribution of sero- common form of pneumococcal disease in adults, types among the vaccinated population. (cdc.gov)

however, at this point, the law had little to do with quarantine other than providing for patient isolation for communicable diseases in the context of clinical care. (nih.gov)
Vaccines, passive immunotherapy, and specific antimicrobial therapy would be developed, and clinical diagnosis, the epidemiology of communicable diseases, and other public health activities, such as quarantine, would be placed upon a solid biological basis. (nih.gov)
NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. (nih.gov)
These vaccines have been extensively studied, are currently in human trial phase 1/2, and seem to be the best treatment choice for pneumococcal diseases, especially for developing countries. (mdpi.com)
Background: Chronic conditions increase the risk of invasive pneumococcal diseases (IPD). (bvsalud.org)

Pyogenic lung infections: factors for predicting clinical outcome of lung abscess and thoracic empyema. (medscape.com)
At present, there are only a few reports samples from patients with clinical indi- globally on resistance of common respira- cations of respiratory tract infections. (who.int)
Severe pneumococcal infections result from dissemination of bacteria to the bloodstream and the central nervous system. (cdc.gov)
Bacterial , viral , and fungal infections can cause pneumonia. (medlineplus.gov)
Pneumococcal disease is contagious, meaning it spreads from person to person and causes thousands of infections every year in the United States. (cnshealthcare.com)
The term ALRI included: acute broncho-pneumonia for bacterial infections, bronchiolitis for viral infections, pneumonia and pleuro-pneumonia. (scirp.org)
If a person is diagnosed with coal worker's pneumoconiosis treatment is typically supportive with timely treatment of respiratory infections, surveillance for mycobacterial infections such as tuberculosis, immunizations for influenza and pneumococcal pneumonia, supplemental oxygen at rest and/or with exertion if needed, smoking cessation, and regular exercise to maintain overall health and good respiratory muscle strength. (nationaljewish.org)

The proportion of pneumococcal pneumonia decreased each year in age-stratified groups, especially in 2-5 year group. (biomedcentral.com)

In contrast, hospital-acquired pneumonia (HAP) is seen in patients who have recently visited a hospital or who live in long-term care facilities. (wikipedia.org)
It has potent in vitro activity and exhibits a high potential to be used in the treatment of ventilator-associated and hospital-acquired pneumonia. (grandviewresearch.com)
Non-ventilator-associated hospital-acquired pneumonia (NV-HAP) is a common and deadly complication of hospitalization that could account for up to 1 in 14 hospital deaths, according to a study published in JAMA Network Open . (pharmacytimes.com)
Despite most cases of hospital-acquired pneumonia occurring in nonventilated patients, there is often only surveillance and prevention programs for ventilator-associated pneumonia and not NV-HAP at most hospitals. (pharmacytimes.com)

Alcohol in the treatment of pneumonia and enteric fever. (jameslindlibrary.org)
Also, various government initiatives aimed at prevention and treatment of pneumonia are responsible for creating a positive impact across North America. (grandviewresearch.com)

A total of 442 pleural fluid effusion samples (PFES) from children with clinical and laboratory diagnoses of acute bacterial pneumonia, plus 38 control PFES from tuberculosis patients and 20 negative control serum samples from healthy children were evaluated by Dot-ELISA. (scielo.br)
Since the number of elderly persons in Spain represents an important population, ∼15% of the overall population 16 , a prospective, multicentre study was undertaken by the current authors' group (Area de Tuberculosis e Infecciones Respiratorias) in elderly patients admitted to hospital for CAP, with the aim of determining the clinical characteristics, aetiology, evolution and prognostic factors of this disease in Spain. (ersjournals.com)

Cite this: Pneumococcal Pneumonia Outcomes Worse Than Legionnaires Disease - Medscape - Mar 30, 2022. (medscape.com)
Rates of invasive pneumococcal disease are exceptionally high among Alaskan Natives and American Indians. (cdc.gov)
Specific to pediatric pneumonia, potential uses of biomarkers include helping to determine etiology to predict disease course, to target therapy, and to determine response to therapy. (medscape.com)
Certain persons with pneumococcal colonization might develop invasive pneumococcal disease (IPD) ( 2 ). (cdc.gov)
In adults, pneumococcal pneumonia is the most common type of pneumococcal disease, and pneumococcus is the most common bacterial cause of pneumonia that results in hospitalization ( 3 ). (cdc.gov)
Pneumococcal disease is the primary cause of childhood morbidity and mortality worldwide, resulting in 0.7 to 1.0 million deaths each year in children younger than age 5 years [ 3 ]. (biomedcentral.com)
The good news is that pneumococcal vaccines can help prevent the disease. (cnshealthcare.com)
Risk of disease remains high in children with underlying conditions that increase the risk of pneumococcal disease. (cdc.gov)
Is pneumococcal disease of public health importance in U.S. children? (cdc.gov)
Increasing incidence of pneumococcal disease is a high impact rendering driver. (grandviewresearch.com)
For instance, Bill & Melinda Gates Foundation is one of the funding bodies that aims at addressing the problem of neonatal pneumococcal disease and promotes development of new vaccines. (grandviewresearch.com)
In addition, the high clinical urgency to adopt systems for efficient management, vital in reducing complications, consequentially drives the demand for oxygen therapy to counter pneumococcal disease. (grandviewresearch.com)
On June 8- 2021- the US FDA has approved Prevnar 20 for the prevention of invasive disease and pneumonia in adults aged ≥18yrs. (pharmashots.com)
More than 300,000 people in the United States are hospitalized annually for pneumonia, according to the Centers for Disease Control and Prevention. (nih.gov)
Ludwig E., Bonanni P., Rohde G., Sayiner A., Torres A.. The remaining challenges of pneumococcal disease in adults. (ers-education.org)
Invasive pneumococcal disease (IPD) is responsible for significant mortality and morbidity worldwide. (biomedcentral.com)
We carried out a prospective observational study of patients with IPD in Nord Trøndelag county in Norway from 1993 to 2011 to study the clinical variables and disease outcome. (biomedcentral.com)
Invasive and non-invasive pneumococcal disease has a high mortality risk, especially in the elderly patient with comorbidities [ 2 ]. (biomedcentral.com)

Establishing reliable clinical and laboratory parameters embedded in a simple diagnostic score that can accurately identify patients with LD may be helpful in aiding physicians' early diagnosis in distinguishing LD from SP but will need to be defined," they concluded. (medscape.com)
Initial diagnosis is usually based on chest x-ray and clinical findings. (msdmanuals.com)
In some immunocompromised patients, who shed the virus for long periods, the diagnosis can be of little clinical significance. (medscape.com)
Dot-ELISA proved to be a practical alternative technique for the diagnosis of pneumococcal pneumonia. (scielo.br)
Classically, the clinical presentation of CAP in the elderly has been described as quite subtle 5 , 6 , thereby leading to a delay in diagnosis and treatment. (ersjournals.com)
Clinical diagnosis and treatment of vaginal or cervical inflammation, abnormal discharge or STI should be a priority. (nzdl.org)
The diagnosis of pneumonia was made by physical and laboratory examination. (biomedcentral.com)
Surveillance case definitions are not intended to be used by healthcare providers for making a clinical diagnosis or determining how to meet an individual patient's health needs. (cdc.gov)

Pneumococcal antigen was detected by counter-current immunoelectrophoresis in the sputum of 79% of patients with purulent sputum, in the serum of 29% of the patients, and in the urine of 54% of the patients. (bmj.com)
A dot-enzyme-linked immunosorbent assay (Dot-ELISA) for pneumococcal antigen detection was standardized in view of the need for a rapid and accurate immunodiagnosis of acute pneumococcal pneumonia. (scielo.br)
Pneumococcal omniserum diluted at 1:200 was employed in this assay for antigen detection. (scielo.br)

Pneumonia can range from mild to severe, depending on what caused it, your age, and your overall health. (medlineplus.gov)
Subanalysis of patients with severe pneumonia did not show differences in clinical outcome. (atsjournals.org)
According and a reduction in hospital mortality from severe to recent estimates, every year about 120-156 million cas- pneumonia ( 4 ). (who.int)

Noteworthy is that LD represented almost as many cases as documented bacteremic pneumococcal pneumonia," the researchers wrote in their discussion. (medscape.com)
Antibiotic combination therapy has been reported to improve outcomes for patients with bacteremic pneumococcal CAP. (infectiousdiseaseadvisor.com)

In addition, data were collected on clinical features including body mass index, systolic and diastolic blood pressure, pulse, respiratory rate, and temperature. (medscape.com)
Viruses that infect the respiratory tract may cause pneumonia. (medlineplus.gov)
Pneumococcus can colonize the upper respiratory tract, most commonly in young children, and is transmitted to others through contact with respiratory droplets from a person with pneumococcal colonization in the upper respiratory tract ( 1 ). (cdc.gov)

With the advent of pneumococcal vaccines, we've seen this decrease in mortality due to a bacterial cause of pneumonia. (medscape.com)

For most children under 5, it really is a viral cause of pneumonia that needs to be treated. (medscape.com)
Viral pneumonia is often mild and goes away on its own within a few weeks. (medlineplus.gov)
If you have viral pneumonia, you are at risk of also getting bacterial pneumonia. (medlineplus.gov)
Because of the difficulty in distinguishing between the various etiologic agents, both viral and bacterial, causing pneumonia, the workup for symptomatic patients with an infiltrate on chest radiograph should include laboratory studies. (medscape.com)
Viral pneumonia can be diagnosed by isolation and identification of the pathogen through viral culture. (medscape.com)

The report also includes clinical guidance for adults who have received 7-valent PCV (PCV7) only and adults who are hematopoietic stem cell transplant recipients. (cdc.gov)

Although occupational exposure to gases, fumes (especially metal fumes), and chemicals is known to be associated with increased risk of pneumonia-related morbidity and mortality, this study is unique in that occupational risk for CAP was assessed in elderly subjects who retired from work and who were simultaneously investigated for environmental air-pollution exposure. (cdc.gov)
In order to contribute to the reduction of the morbidity and the mortality relative to the ALRIs of children in Brazzaville, this study set itself the objective of determining their epidemiological, clinical and evolutionary profiles and to identify the favoring factors and those associated with the risk of death. (scirp.org)
To estimate the incidence, variability, outcomes, and population attributable mortality of NV-HAP, researchers conducted a retrospective cohort analysis of 284 hospitals using an electronic surveillance definition applied to detailed clinical data. (pharmacytimes.com)

He established the Clinical Epidemiology and Biostatistics Unit at the Royal Children's Hospital in 1989, was promoted to Professor in 1999 and became Deputy Head of Paediatrics within the School of Medicine. (edu.au)

Fungal pneumonia is more common in people who have chronic health problems or weakened immune systems . (medlineplus.gov)
His research has been in clinical paediatrics in adjustment to chronic illness and in incontinence, and in immunisation and clinical trials of new vaccines. (edu.au)

His expertise relates to immunisation, pandemic planning and response, clinical trials, research investment in clinical and population health research, research quality, injury control and other areas. (edu.au)
CNS has conducted thousands of clinical trials, improved millions of lives, and is proud to have helped in the FDA approval of nearly 100 new treatments. (cnshealthcare.com)
The market is also predominantly driven by increasing number of ongoing clinical trials for development of vaccines and drug molecules. (grandviewresearch.com)
For example, Merck & Co., Inc. has a product MK-1986that is in phase III of clinical trials. (grandviewresearch.com)
Experimental Ebola treatments or vaccines should only be deployed in clinical trials. (bioedge.org)

Evidence-based design and evaluation of a whole genome sequencing clinical report for the reference microbiology laboratory. (cdc.gov)
Patients with positive blood cultures were registered prospectively by the microbiology laboratory and clinical variables were registered retrospectively from patients' hospital records. (biomedcentral.com)

The global pneumonia therapeutics market size was estimated at USD 11.9 billion in 2016 and is anticipated to grow at a CAGR of 8.0% throughout the forecast period. (grandviewresearch.com)

The Plan was launched in April 2013 in parallel with The Lancet series on childhood pneumonia and diarrhoea. (who.int)
Necrotizing pneumococcal pneumonia in childhood. (lookfordiagnosis.com)

Secondary outcomes were clinical cure at Day 30, length of stay, time to clinical stability, defervescence, and C-reactive protein. (atsjournals.org)

In humans, the increased susceptibility to infectious pneumonia from exposure to metal fumes is thought to be reversible following cessation of exposure. (cdc.gov)
The study supports the hypothesis that regular occupational exposure to gases, fumes, or chemicals at work is associated with increased susceptibility to infectious pneumonia such as CAP and that the effect on increased susceptibility is long-lasting following cessation of exposure. (cdc.gov)

Clinical review: Bedside lung ultrasound in critical care practice. (medscape.com)

These patients generally present with conditions that are more acute in nature and are usually treated while they have bacterial pneumonia. (medscape.com)
r\n','title':'Treatment patterns in patients using triptan and prophylactic medication: an analysis of clinical practice prior to the introduction of CGRP antagonists. (helsana.ch)
A prospective, 12-month, multicentre study was carried out to assess the clinical characteristics, aetiology, evolution and prognostic factors of elderly patients (≥65 yrs) admitted to hospital for CAP. (ersjournals.com)
However, in some reports 7 , 8 the clinical picture has been fundamentally acute with few variations with respect to younger patients. (ersjournals.com)
Hospitalized patients, clinically and radiologically diagnosed with CAP using standard clinical and radiological criteria, were randomized to receive 40 mg prednisolone for 7 days or placebo, along with antibiotics. (atsjournals.org)
Fifty-four (25.4%) patients had a CURB-65 score greater than 2, and 93 (43.7%) patients were in Pneumonia Severity Index class IV-V. Clinical cure at Days 7 and 30 was 84/104 (80.8%) and 69/104 (66.3%) in the prednisolone group and 93/109 (85.3%) and 84/109 (77.1%) in the placebo group ( P = 0.38 and P = 0.08). (atsjournals.org)
inquire into patients' and clinicians' experiences of randomization in order to find out what made this study possible to conduct, and thereby contribute to improve randomization in the futureThe background material was a large randomized clinical trial, the Scandinavian Prostatic Cancer Group Study Number 4, or SPCG-4, which was open for inclusion from February 1989 through December 1999. (kb.se)
Pneumonia was also confirmed by reviewers or bedside clinicians in 202 of 250 patients (81%) on medical record review. (pharmacytimes.com)
Those patients with an impaired response to pneumococcal polysaccharides are diagnosed with a specific antibody deficiency [ 5 ]. (biomedcentral.com)

Abscesses, typical of aspiration pneumonia, usually contain a mixture of anaerobic bacteria. (wikipedia.org)

The new integrated global action plan for the prevention and control of pneumonia and diarrhoea2 gives the global community an historic opportunity to end preventable child deaths, by focusing on pneumonia and diarrhoea in particular, which together account for 26% of all under-five deaths. (who.int)
For instance, the Integrated Global Action Plan for Pneumonia and Diarrhea by UNICEF and WHO is aimed at minimizing preventable child deaths due to diarrhea and pneumonia. (grandviewresearch.com)
In 2009, pneumonia ranked eighth among the 15 leading causes of death in the United States, with adults 55 and older accounting for the majority (92 percent) of all pneumonia-related deaths that year. (nih.gov)

Anatomy2

Diseases14

Chemicals and Drugs2

Information Science1

Community-acquired19

Vaccine50

Polysaccharide8

Serotypes5

Bacteremia8

Vaccination12

Meningitis7

PCV131

Infection14

Immunization5

Conjugate vaccines2

Otitis media1

Sepsis3

Types of pneumococcal1

PPSV231

Pneumoniae9

Detection of pneumococcal antigen2

20201

Lobar pneumonia4

Serotype5

Type of pneumonia1

Cases of pneumonia2

Form of pneumococcal disease1

Diseases5

Infections7

Proportion of pneumococcal1

Hospital-acquired4

Treatment of pneumonia2

Tuberculosis2

Disease18

Diagnosis8

Antigen3

Severe3

Bacteremic pneumococcal2

Respiratory3

Bacterial cause of pneumonia1

Viral5

PCV71

Mortality3

Epidemiology1

Chronic2

Trials5

Microbiology2

20161

Childhood2

Outcomes1

Susceptibility2

Lung1

Patients9

Bacteria1

Deaths3