• This likely could be related to time to assess the endoscopic remission or varying definitions and assessments for endoscopic remission in clinical trials. (medscape.com)
  • Objective To assess if authors of randomised clinical trials convey the fact that they have used surrogate outcomes and discussed their validity. (bmj.com)
  • Participants Randomised clinical trials published in 2005 and 2006 that used a surrogate as a primary outcome. (bmj.com)
  • Results Of 626 published randomised clinical trials, 109 (17%) used a surrogate as a primary outcome. (bmj.com)
  • Of these trials, 62 (57%, 95% confidence interval 47% to 67%) clearly reported that the primary outcome was a surrogate. (bmj.com)
  • Conclusion Only about one third of authors of randomised clinical trials that used a surrogate as a primary outcome reported adequately on the surrogate. (bmj.com)
  • Surrogate outcomes may seem an attractive alternative to clinically relevant outcomes in clinical trials. (bmj.com)
  • and if one or, even better, many randomised trials on similar drug classes have established that the intervention's effect on the surrogate captures the intervention's effect on the clinical outcome. (bmj.com)
  • 5 However, even trials with thoroughly validated surrogates cannot match trials with clinical outcomes, as some uncertainty will always remain. (bmj.com)
  • Therefore results from trials based on surrogates can be difficult for doctors to apply in clinical practice. (bmj.com)
  • We evaluated if authors of randomised clinical trials convey the fact that they have used a surrogate as a primary outcome and have discussed the surrogate's validity. (bmj.com)
  • We searched for all randomised clinical trials published in 2005 and 2006 in JAMA , New England Journal of Medicine , Lancet , BMJ , Annals of Internal Medicine , and PLoS Medicine . (bmj.com)
  • Our confidence in the effects is limited by the risk of bias, heterogeneity and small number of trials conducted to assess outcomes of interest. (cochrane.org)
  • We included randomised trials directly comparing the effects on outcomes and processes of care of PROMs feedback to healthcare professionals and patients, or both with the impact of not providing such information. (cochrane.org)
  • We identified 116 randomised trials which assessed the effectiveness of PROMs feedback in improving processes or outcomes of care, or both in a broad range of disciplines including psychiatry, primary care, and oncology. (cochrane.org)
  • We offer stroke, brain injury, and spinal injury clinical research trials. (casacolina.org)
  • Primary care researchers and rural health professionals are joining forces to provide cancer patients from rural Australia with more equitable access to clinical trials to improve their health outcomes. (ruralhealth.org.au)
  • In parallel, the network will build capacity in primary care to run practice-based clinical trials in rural areas. (ruralhealth.org.au)
  • PARTNER is supported by the Primary Care Collaborative Cancer Clinical Trials (PC4) group, one of 14 national collaborative cancer clinical trials funded by Cancer Australia which aims to increase research capacity and cancer clinical trials. (ruralhealth.org.au)
  • It is becoming increasingly evident that working together with practice-based research networks such as PARTNER will help provide a platform for future clinical trials. (ruralhealth.org.au)
  • One important question that is yet to be definitively answered is how AHSCT stacks up as a treatment against the new generation, highly efficacious therapies available for relapsing MS. However, to date there have been limited clinical trials comparing the success rate of AHSCT with more conventional treatments of relapsing remitting MS. (msaustralia.org.au)
  • This FOA, PAR-23-062 , uses the R01 grant mechanism for applications with preliminary data or those including longitudinal analysis, advanced modeling, large-scale clinical trials or implementation science studies. (nih.gov)
  • He talks about the importance of clinical research in advancing patient outcomes with a focus on clinical trials. (ecancer.org)
  • However, there have been no clinical trials until now to test the efficacy of DMF in reducing inflammation in COVID-19 patients. (news-medical.net)
  • To compare the perspectives of PwPD and HCPs regarding prioritized areas for outcome measurement in clinical PD trials. (lu.se)
  • Recognizing that "well-designed2 and well-implemented clinical trials are indispensable for assessing the safety and efficacy of health interventions" and acknowledging "the importance of promoting equity in clinical trial capability" the Health Assembly sought to improve the quality of evidence generated in clinical trials and their coordination. (who.int)
  • these may refer to women, in particular pregnant and lactating women, children and other populations that are under-represented in clinical trials such as vulnerable and marginalized people. (who.int)
  • In addition to several requests to the Director-General, the Health Assembly identified several possible actions for clinical researchers, trial sponsors, research funders, research ethics committees and national regulatory authorities that are key elements of the clinical trials ecosystem. (who.int)
  • Clinical trials may also be referred to as interventional trials. (who.int)
  • Authors are encouraged to submit to the MDS journals, Movement Disorders or Movement Disorders - Clinical Practice, although acceptance is not guaranteed. (movementdisorders.org)
  • This diverging evidence suggests effective translation into clinical practice of information on cancer cell metabolism acquired by decades of basic research. (cambridge.org)
  • Furthermore, readers will want to know if the surrogate has been validated and is sufficiently reliable to warrant changes in clinical practice, provided the harms of the treatment are acceptable. (bmj.com)
  • Constant review of our clinical outcomes establishes standards against which to continuously improve all aspects of our practice. (gosh.nhs.uk)
  • Despite hypothesised benefits that feedback on PROMs can support decision-making in clinical practice and improve outcomes, there is uncertainty surrounding the effectiveness of PROMs feedback. (cochrane.org)
  • Nephron Clinical Practice (2009) 111 (2): c102-c109. (karger.com)
  • These studies described interventions for improving diet or physical activity as indicators of health promotion and disease prevention and that reported significant improvement in clinical outcomes. (cdc.gov)
  • Here, we retrospectively analyzed the relationship between clinical outcomes and the CONUT score in aSAH patients during hospitalization. (nature.com)
  • Renal replacement therapy is required in notype of hantavirus-infected patients and their long-term 5% of hospitalized patients with acute NE ( 8 , 10 , 13 , 14 ), outcome and humoral immunity to PUUV, we conducted a although some studies report rates of up to 25% ( 15 , 16 ). (cdc.gov)
  • Prominent clinical find- virus infection, long-term follow-up data have not been ings during acute NE were fever and back/limb pain, and reported for a large, representative cohort of patients. (cdc.gov)
  • This project is a detailed re-examination of this group, to define their clinical patterns and genetic markers and compare them with those of previously reported non-WTC-exposed sarcoidosis patients. (cdc.gov)
  • Researchers have now been able to quantify a relationship between physicians' empathy and their patients' positive clinical outcomes, suggesting that a physician's empathy is an important factor associated with clinical competence. (sciencedaily.com)
  • Through a landmark study, a research team from Jefferson Medical College (JMC) of Thomas Jefferson University has been able to quantify a relationship between physicians' empathy and their patients' positive clinical outcomes, suggesting that a physician's empathy is an important factor associated with clinical competence. (sciencedaily.com)
  • For those of us in primary care medicine who have devoted much of our working lives to developing empathic relationships with our patients, research findings of improved patient outcomes among the more empathic physicians is very gratifying indeed. (sciencedaily.com)
  • This can be addressed by agreeing on a minimum core set of outcome measures per health condition, containing measures relevant to patients and decision makers. (nih.gov)
  • Since 1992, the Outcome Measures in Rheumatology (OMERACT) consensus initiative has successfully developed core sets for many rheumatologic conditions, actively involving patients since 2002. (nih.gov)
  • Twelve-member expert panel chosen by steering committee based on scientific and clinical expertise in diagnosing and treating patients with VCF (neurosurgery, interventional neuro radiology, pain medicine, orthopedic surgery). (medtronic.com)
  • Download a summary of the published clinical evidence for deep brain stimulation in epilepsy patients. (medtronic.com)
  • Less certainty exists on the role of nutrition therapy in improving cancer patients' body composition and clinical outcome. (cambridge.org)
  • It is undeniable that medical anti-cancer options significantly improved over the past 10-15 years, yet it is also self-evident that they did not translate into improved outcome for advanced cancer patients in the real world, at least as far as survival rate is considered. (cambridge.org)
  • Patients' age was a strong predictor of surgical outcome, and the size and location of an aneurysm predict both surgical and endovascular outcomes. (nih.gov)
  • In this section, we comprehensively analyzed the expression levels of fourteen m 6 A RNA methylation regulators and clinical factors in patients with HCC from the ICGC (International Cancer Genome Consortium, https://icgc.org/ ), Gene Expression Omnibus (GEO, https://www.ncbi.nlm.nih.gov/geo/ ), and TCGA (The Cancer Genome Atlas, http://cancergenome.nih.gov/ ) databases. (hindawi.com)
  • Comparison of long-term outcomes between peritoneal dialysis patients with diabetes as a primary renal disease or as a comorbid condition. (springer.com)
  • In this study, we examined the association of clinical outcome with the Controlling Nutritional Status (CONUT) score during hospitalization in aSAH patients. (nature.com)
  • These findings indicate that CONUT score during hospitalization may be a useful daily marker for predicting poor outcomes in aSAH patients. (nature.com)
  • The 30-day and 6-month mortality rate is 39% and 49%, respectively, and only 23% of patients have a favorable outcome, as evaluated using a modified Rankin scale (mRS) score of 0-2 2 . (nature.com)
  • These researchers also showed in a prospective observational study of 229 SAH patients that a negative nitrogen balance during the first 14 post-bleed days is a risk factor for infectious complications and is associated with poor outcomes (mRS ≥ 4) at 3 months 11 . (nature.com)
  • 4 at admission independently predicted patients' functional outcome status at 3 months after aSAH 7 . (nature.com)
  • However, it is unclear whether the CONUT score during hospitalization influences the functional outcomes of aSAH patients. (nature.com)
  • In addition to progression of clinical and radiological damage, health related quality of life is reduced among patients with PsA. (bmj.com)
  • To assess the effects of PROMs feedback to patients, or healthcare workers, or both on patient-reported health outcomes and processes of care. (cochrane.org)
  • In a 12-month follow-up randomized clinical trial, we aimed to measure the efficacy of a brief family psychoeducation program in terms of reducing relapse risk and improving medication adherence in patients, as well as reducing caregiver burden, depression and increasing knowledge of the illness. (frontiersin.org)
  • As confirmed by previous studies, the brief multifamily program (consisting of six sessions over a period of 1.5 months) was found to be effective in improving outcomes for caregivers (e.g., burden, depression, knowledge) and patients (e.g., preventing relapse) in the context of routine care. (frontiersin.org)
  • For patients, family psychoeducation has been effective in improving outcomes in schizophrenia with a better level of global functioning, medication adherence, and a reduction in the use of healthcare resources and the frequency of relapse ( 6 - 8 ). (frontiersin.org)
  • A recent systematic review including 11 studies demonstrates consistent improvement in many outcome measures of patients, such as relapse rates and medication adherence, but heterogeneity in symptoms reliefs ( 9 ). (frontiersin.org)
  • In 7 patients (15%), five or more glands were documented and in another four suspected confirming the clinical relevance of intraoperative parathyroid hormone (PTH) measurement. (karger.com)
  • The purpose of this Funding Opportunity Announcement (FOA) is to stimulate collaborative applications that will contribute to the identification and characterization of patients at risk of developing cancer treatment-related cardiotoxicity with the primary intent to mitigate cardiovascular dysfunction while optimizing cancer outcomes. (nih.gov)
  • For instance, the Improving Rural Outcomes Trial recruited nearly 1,400 rural cancer patients in Western Australia to study the combined effects of community and GP level interventions to reduce time to cancer diagnosis. (ruralhealth.org.au)
  • We aimed to describe characteristics, severity and outcome of COVID-19 vaccinated patients admitted in ICU. (ersjournals.com)
  • Associate Professor Tomas Kalincik is utilising data gathered through the world's largest MS clinical database, MSBase as well as other international clinical registers to compare the clinical outcomes of people treated with ASHCT compared with those of similar patients who have been treated with natalizumab, alemtuzumab, fingolimod or mitoxantrone. (msaustralia.org.au)
  • We investigated the effect of vessel recanalization on clinical outcome following local thrombolytic therapy of AIS patients. (ajnr.org)
  • The results indicated that DMF had no beneficial effects on the fifth-day clinical status of the 357 patients who received DMF along with standard care. (news-medical.net)
  • Impact of Procedural Sedation on the Clinical Outcome of Microelectrode Recording Guided Deep Brain Stimulation in Patients with Parkinson's Disease. (iasp-pain.org)
  • Therefore, we performed an observational study to assess the effect of PSA compared to LA alone during STN DBS surgery on outcome in PD patients. (iasp-pain.org)
  • Purpose: To compare the clinical outcomes of MSC injection and arthroscopic marrow stimulation treatment with those of arthroscopic marrow stimulation treatment alone for the treatment of OLTs in older patients. (researchgate.net)
  • Patients were divided into 2 groups: 35 patients (37 ankles) treated with arthroscopic marrow stimulation treatment alone (group A) and 30 patients (31 ankles) who underwent MSC injection along with arthroscopic marrow stimulation treatment (group B). Clinical outcomes were evaluated according to the visual analog scale (VAS) for pain, the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale, and the Roles and Maudsley score. (researchgate.net)
  • Using a cross-sectional method, data on demographics, diabetes status and 6 clinical outcomes of diabetes care were collected from the records of patients who visited the clinics during 2012. (who.int)
  • En recourant à une méthode transversale, des données démographiques, des informations concernant le statut diabétique des patients et six résultats cliniques liés aux soins du diabète ont été collectés à partir des dossiers des patients ayant consulté dans ces établissements en 2012. (who.int)
  • Between 10 and 20% of patients who are infected generally exhibit the clinical syndrome, known as COVID-19. (wikipedia.org)
  • Roughly 81% of patients with clinical COVID-19 experience disorders of smell (46% anosmia, 29% hyposmia, and 6% dysosmia). (wikipedia.org)
  • Huntington's disease (HD) is a rare, neurodegenerative disease and its complex motor, cognitive and psychiatric symptoms exert a lifelong clinical burden on both patients and their families. (lu.se)
  • Patients alive with HD in Sweden in 2018 displayed a pattern of increased clinical burden for a number of years since diagnosis. (lu.se)
  • Clinical characteristics and outcomes (frequency and type of complication, recovery rate and mortality) were evaluated. (who.int)
  • For the subject with type 2 diabetes, the ultimate goal is to reduce cardiovascular outcomes, and in this, achieving glycemic control is just a surrogate endpoint. (dovepress.com)
  • Table 11: Clinical Outcomes for Glycemic Control, Blood Pressure and Cholesterol for Adults with Diabetes by Project Site. (ahrq.gov)
  • Preconception care includes interventions to assess, identify, address, and modify a woman's health conditions and risks to ensure that these health conditions and risks do not negatively affect the outcome of her pregnancy. (bvsalud.org)
  • Our objective was to systematically review the literature on clinical outcomes of diet and physical activity interventions conducted among adult African American populations in the United States. (cdc.gov)
  • We included studies of educational interventions with clinically relevant outcomes and excluded studies that dealt with nonadult populations or populations with pre-existing catabolic or other complicated disorders, that did not focus on African Americans, that provided no quantitative baseline or follow-up data, or that included no diet or physical activity education or intervention. (cdc.gov)
  • Our review suggests that nutrition and physical activity educational interventions can be successful in improving clinically relevant outcomes among African Americans in the United States. (cdc.gov)
  • Our objective was to review available literature on the effect of educational interventions on clinical outcomes resulting from improved nutrition and increased physical activity among adult African Americans in the United States. (cdc.gov)
  • In May 2022, the Seventy-fifth World Health Assembly adopted resolution WHA75.8 on strengthening clinical trials1 to provide high-quality evidence on health interventions and to improve research quality and coordination. (who.int)
  • In resolution WHA75.8 (2022) the Health Assembly requested the Director-General, inter alia, "to organize, in a transparent manner, stakeholder consultations, in line with the Framework of 1 "A clinical trial is defined by WHO as any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes. (who.int)
  • Many reasons could explain the challenges still posed by advanced cancer in achieving clinically meaningful outcomes, among which patient-reported outcomes are gaining more relevance. (cambridge.org)
  • A surrogate outcome has been defined as "a laboratory measurement or a physical sign used as a substitute for a clinically meaningful outcome that measures directly how a patient feels, functions or survives. (bmj.com)
  • Patient-reported outcomes measures (PROMs) assess a patient's subjective appraisal of health outcomes from their own perspective. (cochrane.org)
  • 95% CI 5.81, 8.06) were independent predictors of unfavorable outcome. (who.int)
  • Certain factors may lead to an unfavorable outcome even when treatment is administered rapidly, such as reperfusion injury and hemorrhagic transformation, poor collateral circulation, dehydration, poor cardiac output, hypotension, hyperglycemia, and fever ( 1 - 5 ). (ajnr.org)
  • The SANTE trial provides Level 1 Clinical Evidence for Medtronic Deep Brain Stimulation for Epilepsy. (medtronic.com)
  • The study's outcomes demonstrated the safety, effectiveness and long-term benefits of Deep Brain Stimulation therapy for medically refractory partial-onset (focal) seizures in adults. (medtronic.com)
  • Our objective was to examine the feasibility of hair cortisol concentrations (HCC) as a biomarker to predict clinical pregnancy outcomes and investigate its potential associations with perceived anxiety, resilience, and depressive symptoms. (mdpi.com)
  • There is scientific evidence that the health of women before pregnancy contributes to the maternal and infant outcomes of pregnancy. (bvsalud.org)
  • We reviewed published and un-published literature related to the scientific evidence for the effectiveness of PCC in improving pregnancy outcomes. (bvsalud.org)
  • Optimal development and functioning of the placenta are key factors in maintenance of pregnancy and positively corelate with maternal and fetal outcomes. (cdc.gov)
  • A more definitive efficacy trial of BBT-CI is currently being planned with sufficient statistical power to evaluate the intervention's clinical utility. (healthpartners.com)
  • The aim of the study was to evaluate clinical characteristics, predisposing factors, and outcomes in AIS with HF. (ices.on.ca)
  • For example, a recent review (10) examined physical activity outcomes (ie, increasing frequency of exercise) among African Americans but did not evaluate various health-related outcomes (ie, weight loss or improved lipid profile) resulting from increased exercise. (cdc.gov)
  • The aim of this study was to analyze morbidity and survival after pelvic exenteration for gynecologic malignancies and evaluate prognostic factors influencing postoperative outcome. (bvsalud.org)
  • Although these conclusions about saxagliptin are reasonable, in my opinion this review seems to have put too much emphasis on clinical utility and not enough emphasis on the clinical outcomes of cardiovascular safety and efficacy. (dovepress.com)
  • Although he cited us,3 he overlooked the evidence we provided indicating that the Bacloville article4 was published without acknowledging major changes to the initial protocol, affecting the primary outcome. (psychiatrist.com)
  • The measured primary outcome was the clinical status on the fifth day based on an ordinal scale with seven categories ranging from hospital discharge to mortality. (news-medical.net)
  • MMP is an annual cross-sectional, nationally representative surveillance system that, during 2013-2014, collected information about behaviors, medical care, and clinical outcomes among adults receiving outpatient HIV care. (cdc.gov)
  • This study describes course and outcome over 6 years for Swedish adults with eating disorders. (suicideinfo.ca)
  • The combined and early use of supplemental energies and proteins, as well as modulators of inflammatory response has been shown to improve nutritional status and may also benefit clinical outcome. (cambridge.org)
  • Request a demo to see how ZOLL's solutions can help improve the clinical and operational performance of your business. (zolldata.com)
  • ZOLL has a library of dashboards to improve operational efficiency and clinical outcomes. (zolldata.com)
  • The STEMI Performance dashboard is designed to help improve the outcome of STEMI care through the evaluation of STEMI care across your organization. (zolldata.com)
  • The supplement also describes the economic burdens of HAE, both direct and indirect, and how changes in treatment practices, such as the wider adoption of homebased therapy, may improve patient outcomes and reduce costs. (ajmc.com)
  • Targeted approaches to improving care of the injured victims may improve outcomes. (who.int)
  • Metformin has been shown to improve cardiovascular outcomes in subjects with type 2 diabetes. (dovepress.com)
  • However, saxagliptin alone, or in combination with metformin has not been shown to improve clinical outcomes. (dovepress.com)
  • Clinical pattern a significant risk for morbidity and mortality. (who.int)
  • It is the study of epidemiological and clinical characteristics, the immediate outcome and the factors associated with newborn (NB) mortality with NA. (scirp.org)
  • If the part of neonatal anoxia in neonatal mortality is known in Mali [6] , however, its epidemio-clinical characteristics had never been studied before. (scirp.org)
  • Outcomes were symptomatic intracranial hemorrhage (sICH), 90-day modified Rankin scale (≤ 2 as a good outcome), and 3-month mortality. (ajnr.org)
  • Secondary outcomes included disposition, death at 3 months and at 1 year, and 30-day hospital readmissions. (ices.on.ca)
  • The secondary outcomes were measured based on various parameters, including clinical status improvement time, peripheral blood oxygenation, C-reactive protein levels on the fifth day, and time to discharge. (news-medical.net)
  • Treatment with DMF did not result in any significant improvement in secondary outcomes either. (news-medical.net)
  • It has been thought that the quality of the physician-patient relationship is integral to positive outcomes but until now, data to confirm such beliefs has been hard to find. (sciencedaily.com)
  • This data points to the conclusion that empathic engagement in patient care can contribute to patient satisfaction, trust, and compliance which lead to more desirable clinical outcomes. (sciencedaily.com)
  • We did not find studies reporting on adverse effects defined as distress following or related to Patient-reported outcomes measures (PROM) completion. (cochrane.org)
  • You can easily track your patient refusal rate and identify the outcomes most reported for refusals. (zolldata.com)
  • Patient-reported outcomes (PROs) reflect the experience of health and healthcare as reported directly by the patient. (uab.edu)
  • The Patient-Reported Outcomes Measurement Information System (PROMIS) toolset is a PRO survey system that utilizes computer adaptive testing to provide precise measurements with a minimum number of questions, often shortening conventional PRO surveys by 10-fold or more. (uab.edu)
  • A recent review by Panagoulias and Doupis, published in Patient Preference and Adherence , concerned the saxagliptin/metformin fixed combination (SAXA/MET FDC), and was titled 'Clinical utility in the treatment of type 2 diabetes with the saxagliptin/metformin fixed combination. (dovepress.com)
  • AHRQ Projects funded by the Patient-Centered Outcomes Research Trust Fund. (ahrq.gov)
  • This study in Qatar compared patient outcomes at a primary-care facility with a dedicated diabetes clinic and one without. (who.int)
  • Of eight intracranial hemorrhage events, one SAE in the long-term follow-up resulted in clinical symptoms and was attributed to a head injury after two seizure related falls. (medtronic.com)
  • These coexpression factors (SASH3 and CD53) can be used to classify tumor purity phenotypes and to predict clinical outcomes. (hindawi.com)
  • The objective of this work is to study the epidemiological and clinical characteristics of PA, as well as the immediate outcome of newborns included. (scirp.org)
  • Although studies have revealed the mechanisms involved in cancer malignant characteristics and identified reasonable therapeutic targets [ 4 ], current clinical prediction and treatment outcome of lung cancer are not satisfactory [ 5 ]. (hindawi.com)
  • However, little is known about how end-users such as people with PD (PwPD) and health care professionals (HCPs) view and prioritize therapeutic outcomes. (lu.se)
  • Large lesion size (≥109 mm(2)) and the existence of subchondral cysts were significant predictors of unsatisfactory clinical outcomes in group A (P = .04 and .03, respectively). (researchgate.net)
  • Lack of standardization of outcome measures limits the usefulness of clinical trial evidence to inform health care decisions. (nih.gov)
  • 3 These measures are all considered to be in the causal pathway for the clinical outcome. (bmj.com)
  • The OMERACT Filter 2.0 explicitly describes a comprehensive conceptual framework and a recommended process to develop core outcome measurement sets for rheumatology likely to be useful as a template in other areas of health care. (nih.gov)
  • Using the RAND™/UCLA Appropriateness Method (RAM), a multispecialty expert panel established a comprehensive clinical care pathway for VCF management. (medtronic.com)
  • Management of vertebral fragility fractures: a clinical care pathway developed by a multispecialty panel using the RAND/UCLA Appropriateness Method. (medtronic.com)
  • Clinical outcomes are measurable changes in health, function or quality of life that result from our care. (gosh.nhs.uk)
  • This supplement to The American Journal of Managed Care reviews the pathophysiology, symptoms and clinical course, and diagnostic challenges of hereditary angioedema (HAE). (ajmc.com)
  • Opinions expressed by authors, contributors, and advertisers are their own and not necessarily those of Clinical Care Targeted Communications, LLC, d/b/a Managed Care & Healthcare Communications, LLC, the editorial staff, or any member of the editorial advisory board. (ajmc.com)
  • Clinical Care Targeted Communications, LLC, d/b/a Managed Care & Healthcare Communications, LLC, is not responsible for accuracy of dosages given in articles printed herein. (ajmc.com)
  • Clinical Care Targeted Communications, LLC, d/b/a Managed Care & Healthcare Communications, LLC, disclaims responsibility for any injury to persons or property resulting from any ideas or products referred to in the articles or advertisements. (ajmc.com)
  • April 26, 2023 - Notice of Correction to Due Dates for Letters of Intent for PAR-23-062 "Innovations to Optimize HIV Prevention and Care Continuum Outcomes (R01 Clinical Trial Optional). (nih.gov)
  • In the present study, the efficacy of DMF was tested as part of the randomized evaluation of COVID-19 therapy (RECOVERY) trial being carried out in 177 UK hospitals funded by the National Institute for Health and Care Research Clinical Research Network and 15 non-U.K. hospitals. (news-medical.net)
  • Is diabetes management in primary care improving clinical outcomes? (who.int)
  • Inter-provider comparisons indicated that the outcomes in the facility with a diabetes clinic were not superior to those in the facility with standard care. (who.int)
  • Our purpose is to present a tool for clinical care providers involved in delivering PCC services. (bvsalud.org)
  • The Child Health Clinical Outcome Review's Programme case study of their entry from the 2020 Richard Driscoll Memorial Award (RDMA) can be read in full here . (hqip.org.uk)
  • We searched MEDLINE, Embase, CENTRAL, two other databases and two clinical trial registries on 5 October 2020. (cochrane.org)
  • Our results show that physicians with high empathy scores had better clinical outcomes than other physicians with lower scores. (sciencedaily.com)
  • Time to achieving vessel patency has been shown to be crucial in achieving a better clinical outcome ( 2 - 4 ). (ajnr.org)
  • However, the biological functions' clinical value of other m 6 A-related genes in HCC remains unclear. (hindawi.com)
  • Tumor purity-related coexpression factors in the tumor microenvironment have essential clinical, genomic, and biological significance in lung cancer. (hindawi.com)
  • The clinical and biological data including the prognosis were collected from the health records of women, the liaison sheets and the medical file. (scirp.org)
  • Its effectiveness has also been demonstrated for individuals at clinical high risk for psychosis although rigorous further studies are required ( 10 ). (frontiersin.org)
  • This review examines whether antipsychotic-associated weight gain, when it occurs, is associated with clinical outcome parameters. (psychiatrist.com)
  • We determined postoperative morbidity , 2- and 5-year overall survival (OS) and 2- and 5-year progression free survival (PFS), and investigated parameters influencing these outcomes. (bvsalud.org)
  • The primary intent is to mitigate cardiovascular dysfunction while optimizing cancer outcomes. (nih.gov)
  • For metformin, improved cardiovascular outcomes were shown in the UK Prospective Diabetes Study (UKPDS) 34. (dovepress.com)
  • In summary, we demonstrated the vital role of m 6 A RNA methylation regulators in the initial presentation and progression of HCC and constructed a nomogram which would predict the clinical outcome and provide a basis for individualized therapy. (hindawi.com)
  • It included strict adherence by the multidisciplinary experts to adopt the RAND methodology process, based on published clinical evidence and expertise. (medtronic.com)
  • There was no evidence of clinical bone disease and no pathological fractures after tPTX after a median observation period of 63 months. (karger.com)
  • taking this into account is likely to provide evidence from clinical investigations that are meaningful and interpretable for end-users. (lu.se)
  • Data from the 2013 and 2014 cycles of the Medical Monitoring Project (MMP) were analyzed to describe demographic, behavioral, and clinical characteristics among Hispanics/Latinos by sex. (cdc.gov)
  • Selected sociodemographic and behavioral variables, use of ancillary services, and clinical outcomes are presented by sex. (cdc.gov)
  • t https://unctad.org/system/files/official- document/aldcmisc2020d3_en.pdf. (who.int)
  • 6 hours from the onset of symptoms, is influenced by additional variables that may shift the balance toward good or bad clinical outcomes. (ajnr.org)
  • Provide the region served by the program with graduate clinical laboratory scientists who can function at career entry levels and who can assume leadership roles as health professionals. (neumann.edu)
  • While a considerable number of Australians live in rural areas, they are more likely to have poorer health outcomes and have less access to effective treatment than those living in cities. (ruralhealth.org.au)
  • Focusing clinical investigations on outcomes that are meaningful from an end-user perspective is central in clinical research, particularly in chronic disorders such as Parkinson's disease (PD). (lu.se)
  • Several studies have shown that restoration of cerebral perfusion per se may not be adequate to have a favorable clinical outcome ( 1 - 5 ). (ajnr.org)
  • VANCOUVER, Canada - Intestinal microbiota transplant (IMT), also commonly referred to as fecal microbiota transplant (FMT), significantly improves clinical response and clinical remission among people with inflammatory bowel disease (IBD) compared with standard treatment, a meta-analysis reveals. (medscape.com)
  • Moreover, the authors believe that since the trial was open-label, the knowledge about the treatment could have affected the outcomes. (news-medical.net)
  • Next, at least one applicable measurement instrument for each core Domain is identified to formulate a "Core Outcome Measurement Set. (nih.gov)
  • The proposed list of these two teams and the raters who will participate in the validation phase will be submitted to the Chair of the MDS Clinical Outcome Assessments (COA) Program, Dr. Sheng Luo. (movementdisorders.org)
  • Management outcomes on this topic in the study area is limited. (who.int)
  • This study demonstrates the significant and progressive clinical burden in individuals with HD and presents novel insights into the natural history of JoHD. (lu.se)
  • Diabetes management in both facilities improved clinical outcomes over the 1-year observation period. (who.int)
  • In a clinical phenotype analysis, we found that these five factors can be used as independent prognostic risk factors. (hindawi.com)
  • We have long believed in the importance of empathy and finding measurably better outcomes lends support to our attempts to nurture empathetic medical students and residents who will pursue careers in every kind of medical and surgical specialty," said Fred Makham, M.D., professor, Department of Family and Community Medicine, who is also one of the study's co-authors. (sciencedaily.com)
  • Describe clinical characteristics of acute nephropathia epidemica associated with Puumala virus hantavirus infection, based on a cross-sectional prospective survey. (cdc.gov)
  • To describe the clinical burden and natural history of HD. (lu.se)
  • The degree of recanalization was directly related to time to therapy and associated with good clinical outcome without an increase in the rate of adverse effect. (ajnr.org)
  • Our confidence in these results is limited by the quality and number of included studies for each outcome. (cochrane.org)