Clinical injury. Medical search. Frequent questions

We intend to use this information to develop neurocomputational predictive AI based algorithms that reliably prediction clinical outcomes following CNS injury. (nih.gov)
Prediction of clinical outcomes after CNS injury using cognitive neuroscience and computational linguistics / Dr. Nadia Biassou. (nih.gov)
We studied patients with fluoroquinolone-induced hepatotoxicity from the Drug-Induced Liver Injury Network (DILIN) to characterize injury patterns, outcomes, and associated features. (nih.gov)
This background will inevitably modulate the impact of acute injury on clinical outcomes to an extent that will depend on the precise anatomical pattern of damage. (frontiersin.org)
Optimal prediction of clinical outcomes in stroke then depends on understanding the relation between the patterns of injury and the underlying functional anatomy. (frontiersin.org)
Topical nonsteroidal anti-inflammatory drugs (NSAIDs) were the only treatment option that improved all outcomes in patients with acute pain associated with non-low back, musculoskeletal injuries. (clinicaladvisor.com)
Background Over the past decade, acute kidney injury (AKI) has become a global priority for improving patient safety and health outcomes. (bmj.com)
Not really understanding the methodology ie sentence:but those who visited the ED 48 h after injury, with unknown clinical outcomes. (peerj.com)
BACKGROUND:Individuals with traumatic brain injury (TBI) in Latin America experience high levels of disability and extremely poor functional outcomes, and their informal caregivers play a key role in their rehabilitation and care. (iospress.com)
Patients sustaining a head injury from an assault or from being struck with a falling object have a markedly greater likelihood of poorer vocational outcomes than patients sustaining the more common acceleration/deceleration injuries, presumably because the former injury types entail greater axonal damage. (medscape.com)
The presence of prior head injuries, particularly prior concussive episodes in sports, can indicate the potential for more severe long-term outcomes. (medscape.com)
Both initial and worst GCS postresuscitation scores have correlated significantly with 1-year outcomes following severe head injury. (medscape.com)
Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St. (medscimonit.com)
Our research strategies, which include monitoring and advanced imaging of patients and clinical trials, have made a major contribution to the management and health outcomes of patients with TBI, and also resulted in changes in policy, clinical practice/training and public understanding. (cam.ac.uk)
Given the potential degenerative changes and poor radiographic and clinical outcomes with inadequate repair of the syndesmosis, it is imperative to evaluate existing and emerging methods of fixation for patients with acute ankle fractures with syndesmosis injuries. (ucsd.edu)

Families, soccer players and coaches should be aware of the most common types of injuries -- from sprains and fractures to concussions - so that we can work together to prevent them,' said Andrew Watson, MD, MS, FAAP, a lead author of the report, generated by the AAP Council on Sports Medicine and Fitness. (healthychildren.org)
In the event of traumatic dislocation, soft-tissue lesions of the knee are commonly associated with intra-articular fractures and chondral injuries. (medscape.com)
In a penetrating head injury, an object such as a bullet fractures the skull and enters brain tissue. (encyclopedia.com)
10% of pelvic fractures are associated with bladder injury. (unboundmedicine.com)

More athletes are suffering concussions and anterior cruciate ligament (ACL) injuries, particularly female players. (healthychildren.org)
Other dysfunctions with similar presentations and mechanism of injury are meniscal and ligamentous injuries, particularly injuries of the anterior cruciate ligament . (medscape.com)

Dr. Biassou is a board-certified radiologist at the NIH Clinical Center for the last 15years and holds a joint appointment as staff clinician in the Radiology and Imaging Sciences Department at the NIH Clinical Center and Chief of the Integrative Neuroscience of Communication Research Unit at NIDCD. (nih.gov)
Two studies conducted by the Rehabilitation Medicine Department at the NIH Clinical Center, demonstrated that a blood test of neurofilament light chain can accurately identify all stages - mild, moderate, and severe - of a traumatic brain injury. (nih.gov)

National survey of spinal injuries in hockey players. (medscape.com)

Thus, 10-50% of blunt injuries (and an even greater percentage in penetrating trauma) are diagnosed late. (medscape.com)

The goal of the workshop was to assess the current state of clinical research in acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS), identify research needs, and develop recommendations for clinical research in the near future. (nih.gov)
These studies will also permit continued exploration of biomarkers and genetic factors, to identify subpopulations, predict outcome, facilitate diagnosis, describe pharmacogenomic effects that influence response to therapy, and provide insight into mechanisms of lung injury. (nih.gov)
EGFR-TKI-related adverse events (AEs) are usually tolerable and manageable, although serious AEs, including lung injury (specifically, interstitial lung disease (ILD), causing 58% of EGFR-TKI treatment-related deaths), occur infrequently. (nih.gov)
Methods We designed a case-control study to assess the vaccine effectiveness (VE) against lung injury and referral to hospital. (medrxiv.org)
We estimated the VE against referral for hospital admission, COVID-19-related lung injury assessed with LDCT, and decline in oxygen saturation. (medrxiv.org)
Vaccine protective effect increased with increasing lung injury categories, from 54% (95% CI: 48-60) against any sign of lung injury to 76% (95% CI: 59-86) against more than 50% lung involvement. (medrxiv.org)
This protection is probably mediated through VE against lung injury associated with COVID-19. (medrxiv.org)
However, understanding of the complex pathophysiology of ischaemia-reperfusion-induced lung injury remains incomplete. (ersjournals.com)
Since the late 1990s, scientists have recognised that the different processes following ischaemia-reperfusion, although closely related, cause lung injury by activation of different inflammatory pathways 2 , 4 , 6 . (ersjournals.com)

Torg J. Epidemiology, pathomechanics, and prevention of athletic injuries to the cervical spine. (medscape.com)
In addition to interventions delivered by healthcare providers and systems, this initiative encourages research in community settings, and that integrates individual, family, interpersonal, community, and structural or system (e.g., justice-involved persons or youth in detention, youth involved in child welfare, substance abuse courts) approaches to firearm injury and mortality prevention. (nih.gov)
Click on a disease/condition below to learn more about a range of clinical trials that NIAMS supported and how they contributed to generating new knowledge about prevention and treatment of arthritis, musculoskeletal and skin diseases. (nih.gov)

2020. https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/1688640/all/Bladder_Injury. (unboundmedicine.com)

Presentation at ANZCoS 2019 in Melbourne by Dr Joanne Glinksy "Development of physiotherapy clinical practice guidelines for people with SCI. (burwood.org.nz)
Developingspinal cord injury physiotherapy clinical practice guidelines: a qualitative study to determine how physiotherapists and people living with spinal cord injury use evidence. (burwood.org.nz)

Various obstacles might jeopardize these translational research efforts, however, including the concurrent use of methylprednisolone, a lack of sensitive outcome measures, inconsistencies in clinical management, and the low incidence of SCI within the general population. (medscape.com)
Incidence of nonfatal traumatic brain injury-related hospitalizations - United States, 2018. (medscape.com)
Since the incidence of associated injuries is high, physical findings typically are dictated by these other injuries. (medscape.com)
Incidence of ocular injuries in motor vehicle crash victims with concomitant air bag deployment. (aliem.com)

We have to put into consideration many other factors that may affect the results as other systemic injuries, timing of trauma, timing of arrival at ER, timing of intervention, vital signs and post-operative complications. (scirp.org)
Also consider coexistent cervical spine and other systemic injuries. (medscape.com)

While majority of all traumatic brain injuries are classified as mild (also known as a concussion), it is difficult to diagnose this condition. (nih.gov)

One retrospective study of 25 years of emergency department visits showed the annual number of soccer-related injuries among 7 to 17-year-olds per 10,000 soccer participants increased by 111 % from 1990 to 2014. (healthychildren.org)

In this study, we used Proparacaine (a local anesthetic), in a similar manner, for the outpatient emergency department management of traumatic corneal injuries. (druglib.com)

Traumatic brain injury & concussion: TBI data. (medscape.com)
Among high school athletes with head injuries, on-field "dizziness," but not objective balance impairments, at the time of concussion significantly correlated with prolonged return to play compared to athletes with head injuries who did not experience this symptom. (medscape.com)
The least severe and most common type of TBI is termed a concussion, which is technically defined as a brief loss of consciousness after a head injury without any physical evidence of damage on an imaging study such as a CT or MRI scan. (encyclopedia.com)
In common parlance, concussion may refer to any minor injury to the head or brain. (encyclopedia.com)

200 patients suffering from acute traumatic brain injury causing DCL resulted from different pathologies causing increased ICP. (scirp.org)
The purpose of this study was to evaluate the efficacy of decompressive craniectomy in decreasing ICP by reviewing 200 patients with acute traumatic brain injury with different underlying brain pathologies. (scirp.org)
The study was done prospectively in the Neurosurgery Department, Trauma Causality Unit, Cairo University on patient admitted in the period from June 2014 to June 2016, suffering from acute traumatic brain injury causing DCL resulting from different pathologies causing increased ICP. (scirp.org)

These patients often have associated thoracic and/or abdominal injuries or may have concomitant head or extremity trauma. (medscape.com)
These concomitant injuries contribute to the patient's acute pain. (medscape.com)

The clinical consequences of focal brain injury therefore depend not merely on the volume of damaged tissue but also on its anatomical location ( 1 , 2 ). (frontiersin.org)
Usually, TBI causes focal brain injury involving a single area of the brain where the head is struck or where an object such as a bullet enters the brain. (encyclopedia.com)

If we are able to establish that your child's injuries have been negligently caused, we will undertake a detailed assessment of your child's injuries along with their rehabilitation needs for the rest of their life. (stewartslaw.com)
Because the difficulties caused by mild traumatic brain injury can have wide-ranging neurological, psychological, and psychosocial consequences, both patients and caregivers can benefit from an assessment that identifies and quantifies deficits. (bcmj.org)
The Glasgow Coma Scale (GCS) is the mainstay for rapid neurologic assessment in acute head injury. (medscape.com)
After subsequent assessment of in vivo efficacy, toxicity, pharmacokinetics, and cardiovascular and respiratory safety, SUL-138 emerged as a lead compound that prevented kidney injury after ischemia/reperfusion and demonstrated a favorable pharmacokinetic profile unaffected by renal ischemia. (rug.nl)
From Teasdale G, Jennett B: Assessment and prognosis of coma after head injury, Acta Neurochir (Wien) 34(1-4):45-55, 1976. (clinicalgate.com)

This research Network is focused on Traumatic Brain Injury (TBI), and is designed to evaluate the relationship between acute care practice and rehabilitation strategies, to the long-term functional outcome of TBI patients. (nih.gov)
According to Dr. Leighton Chan, chief of the Rehabilitation Medicine Department at the Clinical Center, "These studies are significant because there is no validated blood test that can reliably detect a traumatic brain injury. (nih.gov)
When cognitive complaints are reported or persist following mild traumatic brain injury in adults, neuropsychological testing can assist with diagnostic issues as well as with treatment and rehabilitation planning. (bcmj.org)
The University at Buffalo (UB) Department of Rehabilitation Sciences is looking for adult volunteers with and without spinal cord injuries to participate in an exercise study. (buffalo.edu)
While reconstruction and subsequent rehabilitation allow these athletes to return to sports, they have a 15-fold increased risk of secondary ACL injuries, a tear of the ACL graft or the contralateral ACL. (nih.gov)

The Glasgow Coma Scale (GCS), first introduced by Teasdale and Jennett in 1974, has been the standard for objectively assessing individuals with traumatic head injuries (Table 2). (medscape.com)
Approximately 75% of head injuries are categorized as mild to moderate in nature. (medscape.com)
An estimated two million head injuries occur in the United States each year. (nih.gov)
Hearing loss is also frequent with sensory neural loss occurring in 20-30% of patients with head injuries. (medscape.com)
These lobes house major brain centers involved in speech and language, so problems with communication skills often follow closed head injuries of this type. (encyclopedia.com)

These are injuries which may be responsible for the long-term symptoms experienced by a significant number of athletes with acute concussions, and patients with more severe brain injuries. (nih.gov)
We are one of the leading firms in England and Wales, with lawyers recognised as leaders in their field for investigating claims for children who have suffered the most severe brain injuries and supporting their families throughout the litigation process. (stewartslaw.com)
We have experience investigating complex claims for children with the most severe brain injuries, including injuries sustained around the time of birth and later in childhood, to establish whether the injuries have been caused by negligent treatment or care. (stewartslaw.com)
Bruising or bleeding on the head and scalp and blood in the ear canal or behind the tympanic membranes may be clues to occult brain injuries. (medscape.com)

Physical examination is limited in its utility in diagnosing this injury, but diaphragmatic injury may be identified by auscultation of bowel sounds in the chest or dullness on percussion of the chest. (medscape.com)
The physical examination in cases of suspected patellar injury and dislocation begins with inspection. (medscape.com)

Symptoms of diaphragmatic injuries frequently are masked by associated injuries. (medscape.com)
Obtaining a thorough history of the patient's symptoms is important when establishing a diagnosis of patellar injury or dislocation. (medscape.com)
There are a wide range of variable behavioral and observational tests to help determine a patient's injuries but most of these tests rely on the patient to self-report signs and symptoms. (nih.gov)
NSAIDs, with or without menthol gel, should be considered a first-line treatment strategy to reduce or relieve pain symptoms associated with the injury. (clinicaladvisor.com)
What are the symptoms of wrist injuries and disorders? (medlineplus.gov)
Symptoms, complaints, and neurological or behavioral changes following TBI depend on the location (s) of the brain injury and on the total volume of injured brain. (encyclopedia.com)

What are the types of wrist injuries and disorders? (medlineplus.gov)
Who is at risk for wrist injuries and disorders? (medlineplus.gov)
How are wrist injuries and disorders diagnosed? (medlineplus.gov)
Can wrist injuries and disorders be prevented? (medlineplus.gov)

Cervical cord neuropraxia (CCN) is a transient neurologic syndrome occurring in athletes with cervical spine injury. (medscape.com)
CCN is especially common in cervical spine injuries resulting from contact sports. (medscape.com)
Trauma to this area, referred to as upper cervical spine trauma, can disrupt the stability of the upper cervical spine and result in a wide spectrum of injury. (lww.com)

Athletes with symptomatic cervical disc injuries commonly present with segmental neck pain, muscle spasm, loss of ROM, and referred pain in both radicular and nonradicular distribution. (medscape.com)
Although the diagnosis may be missed regardless of mechanism, seemingly innocent penetrating injuries may be long forgotten by the patient and are the most commonly missed diaphragmatic injury. (medscape.com)
Bladder injury is often associated with other traumatic injuries, most commonly pelvic fracture. (unboundmedicine.com)

Chondromalacia may be evident by the presence of crepitus, which is a palpable grinding that occurs with knee flexion and extension and occurs secondary to chondral injuries of the patella undersurface and/or the distal femur. (medscape.com)
Isolated internuclear ophthalmoplegia secondary to traumatic brainstem injuries has been described and has a relatively benign prognosis. (medscape.com)
Clinically, DIC can manifest as acute bland (pure) cholestasis, acute cholestatic hepatitis, secondary sclerosing cholangitis (involving bile duct injury), or vanishing bile duct syndrome (loss of intrahepatic bile ducts). (wikipedia.org)

The panel was charged to examine whether novel investigational strategies might allow studies enrolling smaller numbers of patients, and to consider other types of clinical research that would advance the science and treatment of ALI/ARDS. (nih.gov)
The group included pulmonary critical care and cardiovascular clinician scientists experienced in the design and conduct of clinical research as well as statistical and genetic experts. (nih.gov)
RESEARCH OBJECTIVES Background Traumatic Brain Injury (TBI) is a leading cause of death and disability in children and adults. (nih.gov)
This FOA issued by the National Institute on Aging encourages Clinical Trial Planning Grant (R34) applications to develop research protocols for Phase III and IV clinical trials related to critical illness and injury in aging. (nih.gov)
The planning grant mechanism is intended to permit early peer review of the rationale and design of the proposed Phase III or IV clinical trial, and to support development of a research team, tools for data management and research oversight, recruitment strategies, detailed protocol and Manual of Procedures (MOP), and other essential components necessary for a competitive clinical trial application. (nih.gov)
This FOA will utilize the Clinical Trial Planning Grant (R34) mechanism and runs in parallel with PA-10-042 , that encourages applications under the R01 Research Project grant mechanism, PA-10-043 , that encourages applications under the R03 Small Research Grant mechanism, and PA-10-044 , that encourages applications under the R21 Exploratory/Developmental grant mechanism. (nih.gov)
The clinical report also examines research concerning other safety gear, footwear, playing field turf or grass, and environmental conditions. (healthychildren.org)
The identification of patients with AKI recovery who are at high risk for later CKD development remains an important clinical and research goal. (karger.com)
The content of a guideline is based on a systematic review of research literature and clinical evidence - the main source for evidence-based care. (physio-pedia.com)
The aim of clinical guidelines is to improve the quality of care by translating new research findings into practice. (physio-pedia.com)
Research and resulting evidence-based recommendation in the acquired brain injury field impose great difficulties on best practice and clinical guideline development. (physio-pedia.com)
According to Dr. Pashtun Shahim, the first author of both studies, one of the most unexpected learnings from this research is that a blood test with neurofilament light chain could detect the ongoing brain damage that can occur from days to as long as five years after one mild traumatic brain injury event. (nih.gov)
Michelle was part of a published research project with Purdue (Family Dynamics and Self-Injury Behaviors: A Correlation Analysis) and is currently working on developing a state-wide protocol for severe atypical self-injury in congregate care. (selfinjury.com)
This research study explores an area that is relevant to a cross-disciplinary readership and is of considerable relevance to clinical practice. (peerj.com)
The current review highlights the latest research findings in apoptosis after acute lung ischaemia-reperfusion injury. (ersjournals.com)

Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have an acute ankle syndesmosis injury requiring surgery. (ucsd.edu)
Center Tyler Linderbaum was out with an ankle injury. (yahoo.com)

Clinical presentation varies depending on the mechanism of injury (ie, blunt vs penetrating) and the presence of associated injuries. (medscape.com)
We have demonstrated that machine learning models capable of capturing the high-dimensional features of chronic injuries are able to stratify patients-at the time of presentation-by pre-admission and discharge mRS scores. (frontiersin.org)

This report summarizes results of the 1989 survey and compares them with 1988 for risk factors associated with cardiovascular disease, motor-vehicle-related injury, and use of clinical preventive services. (cdc.gov)
Risk factors, such as tobacco exposure, pre-existing lung fibrosis, chronic obstructive pulmonary disease, and poor performance status, indicate that lung inflammatory circumstances may worsen with EGFR-TKI treatment because of impaired epithelial healing of lung injuries. (nih.gov)

Consequences of TBI can be relatively subtle or completely devastating, related to the severity and mechanism of injury. (encyclopedia.com)
The mechanism of traumatic injury is characterized as blunt or penetrating. (unboundmedicine.com)

The overall score generally refers to the best response/examination obtained within the first 6-8 hours after injury and following resuscitation and is considered to be a predictor of the patient's overall outcome. (medscape.com)

The review authors suggested that when one diagnosis is evident, the clinician should further investigate the possibility of the other associated injury. (medscape.com)

Hematoxylin and eosin staining was used to determine liver injury. (medscimonit.com)
Reza and Rabih tackle a case of acute liver injury. (clinicalproblemsolving.com)
Drug-induced cholestasis (DIC) falls under drug-induced liver injury (DILI), specifically the cholestatic or mixed type. (wikipedia.org)

This FOA is NOT designed for collecting preliminary data or conducting pilot studies in support of the scientific rationale for a clinical trial. (nih.gov)
We know from prior studies that stem cell treatment can be effective in aiding with regeneration after spinal cord injury, but many questions remain unanswered," Dr. Bydon says. (mayoclinic.org)
There is limited evidence from preclinical and clinical studies of the mechanisms underlying EGFR-TKI-induced ILD in the available literature. (nih.gov)
The studies also confirmed that neurofilament light chain was more sensitive when compared to 3 other blood biomarkers and imaging at detecting brain damage after a traumatic brain injury. (nih.gov)
Our fully automated chronic stroke lesion segmentation routine simplifies this process, and utilizes routinely collected CT head scans, thereby facilitating future large-scale studies to develop supportive clinical decision tools. (frontiersin.org)
This new ACP/AAFP guideline was based on a network meta-analysis of studies comparing the efficacy and safety of pharmacologic and nonpharmacologic treatments for acute musculoskeletal injuries as well as a systematic review and meta-analysis of predictors of prolonged opioid use following an initial prescription for acute musculoskeletal injuries. (clinicaladvisor.com)
2,3 In the first meta-analysis on pharmacologic and nonpharmacologic treatments, there were a total of 207 studies including 45 therapies administered across 32,959 patients with acute musculoskeletal injuries. (clinicaladvisor.com)
Based on the limited number of studies available, the ACP/AAFP made a conditional recommendation in the guideline for the use of specific acupressure to reduce pain and improve physical function in patients with acute pain from non-low back, musculoskeletal injuries. (clinicaladvisor.com)
Collectively, our phenotype-based screening approach led to the identification of 3 candidates for pre-clinical studies (5%, 3/64). (rug.nl)

Methods: We performed a clinical trial on a sample of adult patients presenting with traumatic corneal injuries to two university affiliated emergency departments in London, Canada. (druglib.com)
Remember to check the corneal pH as alkali-related ocular injuries are potentially blinding and represent a true ophthalmologic emergency. (aliem.com)

Data on mortality attributable to ALI are conflicting, but both longitudinal observations at single institutions and the experience of the NHLBI ARDS Clinical Trials Network suggest a substantial decline over the past two decades. (nih.gov)

NIMHD invites applications that focus on populations that experience health disparities (who are often disproportionately impacted by firearm injury and mortality): specifically, Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities. (nih.gov)

Consequently, clinical trials powered to detect differences in mortality may require ever increasing numbers of patients. (nih.gov)
The objective of this program is to facilitate study of these clinical practices by establishing a Network of Clinical Network Sites and a Data Coordinating Center (DCC) that, by rigorous patient evaluation using common protocols, can study the required numbers of patients and can provide answers more rapidly than individual centers acting alone. (nih.gov)
This increase in the rate of survival from severe brain injury means that there will be an increasing number of patients in need of effective treatment to help them attain a satisfactory long-term life adjustment and quality of life following their injury. (nih.gov)
Plicae can be palpated in many patients with patellar injury. (medscape.com)
Acute kidney injury (AKI) occurs in up to 20% of patients admitted to hospital and results in significant morbidity and mortality [ 1 ]. (karger.com)
Mayo Clinic is enrolling patients in a phase 1 clinical trial of adipose stem cell treatment for spinal cord injury caused by trauma. (mayoclinic.org)
To qualify for the trial, patients must have a spinal cord injury of grade A or B on the American Spinal Injury Association (ASIA) Impairment Scale. (mayoclinic.org)
Three patients each present with cognitive complaints following a history of mild traumatic brain injury (mTBI). (bcmj.org)
The second meta-analysis included 14 observational cohorts with 13,263,393 patients who were prescribed opioids for acute musculoskeletal injuries. (clinicaladvisor.com)
Oral NSAIDs are also recommended for patients with acute pain from non-low back, musculoskeletal injuries. (clinicaladvisor.com)
History in most patients with head injury should be self-evident. (medscape.com)

Even a questionable loss of consciousness can be a marker of severe neurological injury. (medscape.com)

The majority of youth soccer injuries result from player-to-player contact, with a significantly higher proportion of injuries occurring during competition rather than practice, according to one study. (healthychildren.org)
The phase IV clinical study analyzes which people take Etodolac and have Head injury. (ehealthme.com)
The goal of the study is to learn more about the brain and bodily responses to exercise in people with and without spinal cord injuries. (buffalo.edu)
The results of this study will hopefully improve the quality of life for adults with spinal cord injuries. (buffalo.edu)
This is a cross-sectional study that will examine the effect size of the cerebrovascular, cardiac autonomic, and cognitive measures in individuals with spinal cord injury and non-injured controls pre- and post-acute exercise. (buffalo.edu)
A propos d'un cas [Air bags and eye injuries: chemical burns and major traumatic ocular lesions-a case study]. (aliem.com)
Unlike any other organ in the human body, the lung possesses two blood supply networks with extensive anastomotic connections and a total of three potential sources of lung tissue oxygenation, thus making lung ischaemia-reperfusion injury more intriguing to study 2 . (ersjournals.com)

Methods of guideline development have progressed both in terms of process and necessary procedures, and the context for guideline development has changed, with the emergence of Guideline Clearinghouses and large scale guideline production organisations e.g National Institute for Health and Clinical Excellence (NICE). (physio-pedia.com)
The American College of Physicians (ACP) and the American Academy of Family Physicians (AAFP) have released a new clinical guideline on the management of acute pain associated with non-low-back, musculoskeletal injuries in adult outpatients. (clinicaladvisor.com)
It is important to note that in cases of severe injury, the guideline suggests topical NSAIDs may not appropriate as a first-line approach. (clinicaladvisor.com)

Thought you might appreciate this item(s) I saw in Clinical Spine Surgery. (lww.com)
He has also served as deputy editor/editor of Clinical Spine Surgery. (lww.com)
Obstetric injuries and gynecologic surgery are the most common causes of iatrogenic bladder injury. (unboundmedicine.com)
The central role of lung ischaemia-reperfusion injury in pulmonary dysfunction after cardiac surgery, particularly thoracic organ transplantation, has been well recognised. (ersjournals.com)
Ischaemia-reperfusion-induced pulmonary dysfunction is a significant clinical problem in cardiac surgery and, particularly, lung transplantation 1 . (ersjournals.com)

Demographic, clinical, and laboratory data were analyzed by descriptive statistical methods. (nih.gov)

The NIH Clinical Center is not responsible for the availability, content or accuracy of this external site. (nih.gov)

Participants in the phase 1 clinical trial must have experienced a trauma-related spinal cord injury from two weeks to one year prior to enrollment. (mayoclinic.org)
In a previous phase 1 clinical trial, with results published in the Nov. 22, 2016, issue of Neurology, Mayo Clinic researchers found that therapy was safe for people with amyotrophic lateral sclerosis (ALS). (mayoclinic.org)
Dr. Windebank is also involved in the new clinical trial for people with traumatic spinal cord injuries. (mayoclinic.org)
In addition to experience, Mayo Clinic brings to this clinical trial the strength of its multidisciplinary focus. (mayoclinic.org)
A multi-site clinical trial showed that brain imaging was able to identify certain people who could benefit from a thrombectomy for up to 16 hours after a stroke. (nih.gov)
In an early phase clinical trial, a combination of two antibodies suppressed blood levels of HIV for months after treatment in some people. (nih.gov)
For healthy older adults, however, a large clinical trial found that a daily low-dose aspirin doesn't prolong life or help prevent heart disease, physical disability, dementia, or stroke. (nih.gov)

The effects of endothelin-1 (ET-1) on mucosal mast cells are of special interest, since they may be an important component of the tissue response that occurs during ischaemic preconditioning or ischaemia/re-oxygenation injuries. (portlandpress.com)
Urethral injury occurs in 15% of cases of bladder rupture ( 1 )[ C ]. (unboundmedicine.com)
17 Bland cholestasis occurs when there is obstruction to bile flow in the absence of inflammation or biliary and hepatic injury, whereas these features are present in cholestatic hepatitis. (wikipedia.org)

Elicit the type and mechanisms of the injury, as these may have prognostic value. (medscape.com)

Approximately 50 thousand of these individuals will have persistent physical, cognitive, behavioral and social deficits that may compromise their quality of life, as a result of their injury. (nih.gov)
This FOA is comprehensive in its consideration of those at risk for victimization and/or persons responsible for firearm injuries across the lifespan and across sexual and gender identities, people with developmental disabilities or cognitive impairments (i.e. (nih.gov)
The process typically begins with a clinical interview and then continues with tests that assess function in various cognitive and emotional domains. (bcmj.org)

Post-operative pulmonary dysfunction following the use of cardiopulmonary bypass is a frequently observed phenomenon that is associated with lung ischaemia-reperfusion injury 2 , 3 . (ersjournals.com)
Since the mid-1980s, the role of neutrophils, free radicals and other inflammatory mediators in ischaemia-reperfusion injury has been extensively investigated 4 . (ersjournals.com)
Nevertheless, these mediators appear to contribute only in part to lung ischaemia-reperfusion injury. (ersjournals.com)
Tissue necrosis after lung ischaemia-reperfusion injury has been recognised to be associated with significantly worsened lung function, related to the high degree of inflammation. (ersjournals.com)

This review examines the evidence linking acute kidney injury (AKI) with the risk of subsequently developing chronic kidney disease (CKD). (karger.com)
Acute kidney injury (AKI) is a global healthcare burden attributable to high mortality and staggering costs of dialysis. (rug.nl)

Clinical expression of neurotoxic injury and diagnostic use of electromyography. (nih.gov)
She obtained her training in clinical general diagnostic radiology from Georgetown University Hospital with subspecialty fellowship training in neuroradiology from the Hospital of the University of Pennsylvania. (nih.gov)
Assessing mild traumatic brain injury is the second most frequent diagnostic activity in clinical neuropsychology. (bcmj.org)

The GCS is often used to categorize the severity of head injury as mild (15-13), moderate (12-9), or severe (≤8). (medscape.com)
In general, mild head injury does not usually involve significant primary brain injury, is not associated with neurologic deficits, and may or may not include loss of consciousness. (medscape.com)

Since older adults are at a greater risk of being inactive due to injury, illness or sedentary behavior, it is thought that anabolic resistance to amino acids may contribute to the development of sarcopenia. (nih.gov)

Anatomy30

Organisms8

Diseases102

Chemicals and Drugs24

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Phenomena and Processes21

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena13

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Named Groups2

Health Care31

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Outcomes15

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Lung injury9

Prevention3

20201

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Concussion4

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Assessment5

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Head injuries5

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Physical Examination2

Symptoms6

Disorders4

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Research15

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