• One-year cumulative incidence (CI) in the matched ICI vs. targeted and ICI vs. cytotoxic chemotherapy were 6.3% vs. 5.7% (p=0.07) and 4.95% vs. 4.08% (p=0.90) respectively ( table 1 ). (bmj.com)
  • Cumulative incidence of stroke was significantly higher in patients on anti-CTLA-4 monotherapy and anti-CTLA-4 plus anti-PD-1 combination therapy in comparison to anti-PD-1/PD-L1 monotherapy. (bmj.com)
  • At five years, the cumulative incidence of dyskinesia (excluding the three patients who had dyskinesia at base line), regardless of levodopa supplementation, was 20 percent (36 of 177 patients) in the ropinirole group and 45 percent (40 of 88 patients) in the levodopa group. (nih.gov)
  • We will estimate cause-specific mortality rates for people with systemic sclerosis and matched controls and using the cumulative incidence function. (cprd.com)
  • The findings, published today in JAMA , challenge the use of claims data for sepsis surveillance and suggest that clinical surveillance using electronic health record data provides more objective estimates of sepsis incidence and outcomes. (sciencedaily.com)
  • The research team, led by Chanu Rhee, MD, MPH, a critical care and infectious disease physician at BWH, developed a new strategy to track sepsis incidence and outcomes using electronic clinical data instead of insurance claims. (sciencedaily.com)
  • In addition, the researchers assessed whether sepsis incidence and outcomes have been changing over time. (sciencedaily.com)
  • Dr. Rhee and colleagues recommend that sepsis surveillance efforts shift from claims data to the clinical method they used in their study in order to help health professionals, hospitals, and policy makers gain a better understanding of sepsis incidence, outcomes, and trends. (sciencedaily.com)
  • Main outcomes and measures: Hospital and population incidences of sepsis, case fatality, antimicrobial resistance, and temporal dynamics due to COVID-19 were assessed, as well as validity of ICD-10 case identification methods compared with the reference standard of clinical medical record review. (lu.se)
  • Protective perioperative ventilation has been shown to improve outcomes and reduce the incidence of postoperative pulmonary complications. (frontiersin.org)
  • A scoping review of real-time automated clinical deterioration alerts and evidence of impacts on hospitalised patient outcomes. (ahrq.gov)
  • Our objectives were to estimate the incidence of prescribing errors in inpatients in this hospital, to describe the stages of the inpatient stay in which they happen, to explore where in the prescribing process they occur, and to evaluate their clinical significance. (bmj.com)
  • To estimate the incidence of diabetic retinopathy in relation to retinopathy grade at first examination and other prognostic characteristics. (diabetesjournals.org)
  • i) To estimate the incidence, prevalence, mortality ii) Describe health service usage before and after diagnosis and iii) Describe leading causes of death in systemic sclerosis in the UK using the CPRD and linked HES and ONS mortality data. (cprd.com)
  • The objective of this comparative study was to determine the incidence and sites of occurrence of perforations on anatomical sterile gloves used by students of dentistry during the Periodontics and Oral Surgery clinical procedures. (bvsalud.org)
  • The aim of this prospective study was to determine the incidence of LOPI in high risk women with a normal UA RI and assess which clinical variables are associated with this. (sun.ac.za)
  • Aim: the purpose of this study was to characterise postmenopausal women attending osteoporosis centres in Italy, to evaluate physician management, and to determine the incidence of first osteoporotic fracture. (unito.it)
  • Baseline prevalence and incidence of all three infections was calculated by sex and age group. (bmj.com)
  • There is a paucity of data on incidence, prevalence and mortality associated with non-cystic fibrosis bronchiectasis. (ersjournals.com)
  • Using the Clinical Practice Research Datalink for participants registered between January 1, 2004 and December 31, 2013, we determined incidence, prevalence and mortality associated with bronchiectasis in the UK and investigated changes over time. (ersjournals.com)
  • The incidence and point prevalence of bronchiectasis increased yearly during the study period. (ersjournals.com)
  • Bronchiectasis is surprisingly common and is increasing in incidence and prevalence in the UK, particularly in older age groups. (ersjournals.com)
  • Using primary care data (Clinical Practice Research Datalink (CPRD)), we aimed to establish the incidence and prevalence of non-cystic fibrosis bronchiectasis in UK adults from 2004 to 2013. (ersjournals.com)
  • Population-based prevalence and incidence studies are essential for understanding the burden of frontotemporal dementia (FTD). (cambridge.org)
  • The MEDLINE and EMBASE databases were searched to identify population-based publications from 1985 to 2012, addressing the incidence and/or prevalence of FTD. (cambridge.org)
  • Krampe, S. , de Andrade, N. , da Silveira, L. and Brenol, C. (2020) Prevalence and Incidence of Metabolic Syndrome in a Cohort of Patients with Rheumatoid Arthritis: A Correlation between Body Mass Index and Disease Activity. (scirp.org)
  • i) We will identify all cases of systemic sclerosis in the CPRD 1995-2014, and estimate incidence and prevalence using the whole CPRD as the denominator population. (cprd.com)
  • We will investigate the effects of the a priori confounders age, sex and socio-economic status on incidence using multi-variable Poisson regression, and on prevalence using logistic regression. (cprd.com)
  • However, reliably measuring sepsis incidence and trends is challenging because clinical diagnoses of sepsis are often subjective and claims data, the traditional method of surveillance, can be affected by changing diagnosis and coding practices over time. (sciencedaily.com)
  • In contrast to prior claims-based estimates, they found no significant changes in adult sepsis incidence or in the combined outcome of hospital death or discharge to hospice between 2009 and 2014. (sciencedaily.com)
  • No significant increase in sepsis during the COVID-19 pandemic nor a decrease in sepsis incidence when excluding COVID-19 sepsis was observed. (lu.se)
  • Supplying administrative data with information from clinical medical records can help to generate reliable data on sepsis epidemiology. (lu.se)
  • Cancer incidence data from CDC's National Program of Cancer Registries and the National Cancer Institute's Surveillance, Epidemiology, and End Results program were used to calculate average annual age-adjusted incidence rates for 2009-2013 and trends in annual age-adjusted incidence rates for 2004-2013. (cdc.gov)
  • We report on the incidence, genetic diversity, and molecular epidemiology of sapoviruses detected in domestic pigs in a comprehensive study conducted in six European countries (Denmark, Finland, Hungary, Italy, Slovenia, and Spain) between 2004 and 2007. (lu.se)
  • Therefore, improving the recognition of the clinical features of recurrent NPC is of great significance to improving early diagnosis, early treatment, and the long-term survival rate for patients with recurrent NPC. (hindawi.com)
  • The criteria for diagnosis of recurrence without biopsy proof were based on progression of clinical symptoms and/or signs that are compatible of new image findings. (hindawi.com)
  • Ten of them developed malignancy after the diagnosis of IgG4-RD, given a standard incidence ratio (SIR) of 2.78 (95%CI 1.33-5.12). (nature.com)
  • From this database, clinical medical records were also selected for review within 6 strata defined by ICD discharge diagnosis (both with and without sepsis diagnosis). (lu.se)
  • Diagnosis and clinical management remain a challenge and all efforts are focused on vector control with active community involvement. (who.int)
  • Differences between nonmetropolitan and metropolitan counties in cancer incidence might reflect differences in risk factors such as cigarette smoking, obesity, and physical inactivity, whereas differences in cancer death rates might reflect disparities in access to health care and timely diagnosis and treatment. (cdc.gov)
  • Asbestosis has no unique pathognomonic signs or symptoms, but diagnosis is made by the constellation of clinical, functional, and radiographic findings as outlined by the American Thoracic Society [American Thoracic Society 2004]. (cdc.gov)
  • This is a monthly journal (10 issues) that publishes scientific articles of all areas within its specialty: clinical anesthesia, resuscitation-intensive medicine and critical care, diagnosis and treatment of acute and chronic pain, urgent care and emergencies and studies on basic science and related fields. (elsevier.es)
  • To describe the clinical characteristics of the patients who suffered from relapse after conventional irradiation for nasopharyngeal carcinoma (NPC). (hindawi.com)
  • We sought to describe the incidence and clinical characteristics of malignancies in patients with IgG4-RD. Based on these results, significant factors were evaluated to determine whether they were related to malignancy. (nature.com)
  • This study documents for the first time the clinical and epidemiological characteristics of lung cancer cases in Qatar from 1998 to 2005. (who.int)
  • The aim of the present study was to document the clinical and epidemiological characteristics of lung cancer cases in Qatar. (who.int)
  • High incidence of group C streptococci isolated from throat swabs. (bmj.com)
  • Among Indian HIV-infected women, we found a high incidence of postpartum TB and associated postpartum maternal and infant death. (nih.gov)
  • It is therefore of the utmost importance to develop surveillance strategies and management protocols to reduce the incidence of FGR or, failing that, improving their outcome. (sun.ac.za)
  • Clinical VSP was defined as neurological deficits unexplained by another etiology . (bvsalud.org)
  • Conclusions Root canal instrumentation following the manufacturer's instructions can be performed with Reciproc instruments with a very low incidence of instrument fracture and deformation. (scivee.tv)
  • Conclusions This study, the largest ever reported on the age and sex specific incidence of any one of these three curable infections, has identified extremely high rates of new infection in young people. (bmj.com)
  • Conclusions Incidence estimates and incidence rate ratios derived using methods that rely on the changing antibody level over the course of HIV infection may be vulnerable to bias when applied to populations who choose the time of their own testing. (bmj.com)
  • This report provides a comprehensive assessment of cancer incidence and deaths by cancer type in nonmetropolitan and metropolitan counties. (cdc.gov)
  • During the most recent 5-year period for which data were available, nonmetropolitan rural areas had lower average annual age-adjusted cancer incidence rates for all anatomic cancer sites combined but higher death rates than metropolitan areas. (cdc.gov)
  • This study found that the overall incidence of inguinal hernia diagnoses between 2010 and 2019 among U.S. active component service members was 34.3 per 10,000 person-years. (health.mil)
  • Researchers determined that the overall incidence of infection was 9.2 per 10,000 injections. (thehorse.com)
  • The age-standardised incidence of conjunctival melanoma increased significantly in men (n = 89) from 0.10 cases/million to 0.74 cases/million (p = 0.001) and in women (n = 81) from 0.06 cases/million to 0.45 cases/million (p = 0.007). (bmj.com)
  • Our research shows that wide-spread sepsis surveillance using clinical data is feasible and correlates well with expert physicians' diagnoses. (sciencedaily.com)
  • Although the incidence of inguinal hernia diagnoses among active component service members decreased modestly during the surveil ace period, the rate of hernia repair peaked in 2013, and the frequency of diagnoses of pain following hernia repair increased between 2010 and 2019. (health.mil)
  • To address this issue, it is important to identify the incidence of the problem, the diagnoses, presentation and symptoms. (vestibular.org)
  • Incidence and prevention of iatrogenic urethral injuries. (ahrq.gov)
  • Data regarding demographics, clinical features, treatment and prognosis of IgG4-RD patients complicating malignancies were collected and compared to those of age- and sex-matched controls. (nature.com)
  • This content provides clinicians and public health professionals with key information and evidence for clinical considerations when diagnosing and managing pediatric patients infected with SARS-CoV-2, the virus that causes COVID-19. (cdc.gov)
  • Of the patients with clinical sepsis, 232 (51%) were female, and 357 (78%) had at least 1 comorbidity. (lu.se)
  • The incidence of sepsis in hospitalized patients according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) criteria in 2019 was 4.1% (95% CI, 3.6-4.5) by medical record review. (lu.se)
  • Clinical VSP was found in 26% of EC and 40% of SC patients (P (bvsalud.org)
  • Most patients with CMV infection exhibit few clinical findings on physical examination. (medscape.com)
  • The aim of this study was to evaluate the components of MS in patients with RA during a long-term follow-up, as well as to correlate the variation with clinical and laboratory parameters of the disease. (scirp.org)
  • This Health Alert Network (HAN) Health Advisory serves to alert clinicians and public health officials throughout the country to consider melioidosis in patients whose clinical presentation is compatible with signs and symptoms of the disease, regardless of travel history to international disease-endemic regions, as melioidosis is now considered to be locally endemic in areas of the Gulf Coast region of Mississippi. (cdc.gov)
  • Previous large observational studies have reported that patients with asthma have a higher incidence of cardiovascular diseases (such as acute myocardial infarction and stroke) through chronic activation of inflammatory cytokines followed by systemic and vascular inflammation. (aaaai.org)
  • The benefits of the protective mechanical ventilation with low tidal volume (V T ) resulting in improved outcome have been convincingly proved in patients with acute respiratory distress syndrome (ARDS) in large clinical studies and meta-analyses ( 2 , 3 ). (frontiersin.org)
  • Glatopa (glatiramer acetate injection) is an immunomodulator used to treat patients with relapsing forms of multiple sclerosis (MS), including those who have experienced a first clinical episode and have magnetic resonance imaging (MRI) features consistent with MS. Glatopa is generic version of Copaxone . (rxlist.com)
  • Women without prevalent fracture were eligible to enter the 1-year follow-up phase: the clinical approach to patients according to their fracture risk profile and the incidence of fracture were recorded. (unito.it)
  • Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. (rxlist.com)
  • Studies have found that compared with adults, children may have similar or higher incidence rates of SARS-CoV-2 infection but more frequently experience asymptomatic infection or less severe symptoms 3 , 4 , 5 . (cdc.gov)
  • Objectives The serologic testing algorithm for recent HIV seroconversion (STARHS) calculates incidence using the proportion of testers who produce a level of HIV antibody high enough to be detected by ELISA but low enough to suggest recent infection. (bmj.com)
  • New research led by investigators at Brigham and Women's Hospital estimates the current U.S. burden of sepsis and trends using clinical data from the electronic health record systems of a large number of diverse hospitals. (sciencedaily.com)
  • This pilot study sought to investigate their incidence in one UK hospital. (bmj.com)
  • This paper describes a pilot study of the incidence, types, and clinical significance of prescribing errors in a UK hospital. (bmj.com)
  • The HVT group had significantly higher incidence of atelectases ( n = 6), despite lower incidence of smoking compared with the LVT ( n = 1) group ( p = 0.017) and demonstrated longer length of hospital stay. (frontiersin.org)
  • In major pancreatoduodenal interventions, preventively protective V T improves postoperative oxygenation, reduces the incidence of atelectases, and shortens length of hospital stay. (frontiersin.org)
  • Complicaciones de la analgesia continua invasiva para el control del dolor agudo postoperatorio en un hospital de tercer nivel. (elsevier.es)
  • The incidence of POH at our hospital was comparable to the global incidence. (anesthesiaexperts.com)
  • This prospective cohort study aims to investigate the incidence, related factors and prognosis of IgG4-related disease (IgG4-RD) with malignancies in the Chinese cohort. (nature.com)
  • We conclude that an increased incidence of malignancy was found in Chinese IgG4-RD cohort. (nature.com)
  • Methods A cohort-based incidence estimator and two STARHS methods were applied to identical populations (n=3821) tested for HIV antibody at publicly funded sites in Seattle. (bmj.com)
  • In the analysis of 4,607 adults hospitalized for acute asthma who had a first episode of acute myocardial infarction or ischemic stroke, the researchers found that acute asthma was associated with a 5-fold higher incidence of acute myocardial infarction and ischemic stroke, particularly in the first 1-week period after acute asthma. (aaaai.org)
  • Older service members, males, non-Hispanic whites, and those in combat-specific occupations had comparatively higher incidence rates. (health.mil)
  • Nonmetropolitan rural counties had higher incidence of and deaths from several cancers related to tobacco use and cancers that can be prevented by screening. (cdc.gov)
  • The age-specific incidence was higher in men and women ⩾65 years (1.48 and 1.39 cases/million, respectively) than in younger men and women (0.3 and 0.2 cases/million, respectively). (bmj.com)
  • The 50 mg market tablet was equivalent, with respect to AUC, to the tablet used in the dose ranging clinical trials, while the C max was approximately 30% higher. (nih.gov)
  • Deformation and fracture incidence of Reciproc instruments: a clinical evaluation. (scivee.tv)
  • Aim To investigate the incidence of fracture and deformation observed on Reciproc instruments after clinical use. (scivee.tv)
  • Overall seroincidence estimates, demographically stratified estimates and incidence rate ratios were compared across methods. (bmj.com)
  • Incidence ratios derived using STARHS between demographic strata were not consistent across methods. (bmj.com)
  • Cardiopulmonary parameters and the incidence of complications were registered during surgery and postoperatively. (frontiersin.org)
  • In an article recently published in The Journal of Allergy and Clinical Immunology: In Practice , Raita and colleagues investigated the effect of acute asthma on cardiovascular diseases. (aaaai.org)
  • The Journal of Allergy and Clinical Immunology: In Practice is an official journal of the AAAAI, focusing on practical information for the practicing clinician. (aaaai.org)
  • Rebound congestion and rhinitis medicamentosa: Nasal decongestants in clinical practice. (wikipedia.org)
  • Impact of ruptured cerebral aneurysm coiling and clipping on the incidence of cerebral vasospasm and clinical outcome. (bvsalud.org)
  • The study population consisted of all women referred by the clinical (nursing or medical) staff to the Fetal Evaluation Clinic (FEC) or ultrasound unit at TBH for UA RI assessment according the current Western Cape Ultrasound policy. (sun.ac.za)
  • Objectives: To generate reliable epidemiological estimates by linking data from a population-based database to a reference standard of clinical medical record review. (lu.se)
  • Twenty-four of 715 HIV-infected women who were followed up for 480 postpartum person-years developed TB, yielding a TB incidence of 5.0 cases per 100 person-years (95% confidence interval [CI], 3.2-7.4 cases per 100 person-years). (nih.gov)
  • The annual relative change in age-standardised incidence was 16.9% (95% confidence interval (CI) 12.2 to 21.6) in men and 19.5% (95% CI 9.3 to 29.7) in women. (bmj.com)
  • This analysis was conducted to ascertain whether estimates of incidence derived using STARHS were consistent with estimates derived using a method more robust against motivated testing. (bmj.com)
  • In settings where pregnancy dating is far less accurate than in developed countries and where customised growth charts are not available, it may not be appropriate to base management algorithms on the expected fetal weight (EFW) centile as inaccurate clinical or relatively late ultrasound dating (after 20 weeks) may not have allowed the EFW to drop below the 10th centile for the assumed (and perhaps underestimated) gestation. (sun.ac.za)
  • This report establishes new CDC guidance that includes recommendations for a testing algorithm and clinical management for HCP with potential occupational exposure to hepatitis C virus (HCV). (cdc.gov)
  • Health care providers can use this guidance to update their procedures for postexposure testing and clinical management of HCP potentially exposed to hepatitis C virus. (cdc.gov)
  • Multivariate analysis showed that SC doubled the risk of clinical VSP (P risk of composite VSP (P (bvsalud.org)
  • Objectives To undertake the first comprehensive analysis of the incidence of three curable sexually transmissible infections (STIs) within remote Australian Aboriginal populations and provide a basis for developing new control initiatives. (bmj.com)
  • No statistically significant change was seen in states that offered only religious exemptions or that had medium and difficult exemption processes. However, the researchers also found that easier granting of exemptions was associated with a 53 percent increased incidence of pertussis, and the availability of personal belief exemptions was associated with a 48 percent increased incidence. (infectioncontroltoday.com)
  • Domestic and foreign studies have indicated that the clinical features of recurrent NPC may be different from primary NPC. (hindawi.com)
  • The incidence of CMV seropositivity rises with age and in a US-based study was reported to increase from 36% in children aged 6-11 years to 91% in individuals older than 80 years. (medscape.com)
  • In one of the first investigations of its kind, the study of more than 3000 fifth-grade students in Nova Scotia, Canada, showed that those who met at least seven of nine healthy lifestyle recommendations had a substantially lower incidence of ADHD compared to their counterparts who only met between one and three of the criteria. (medscape.com)
  • TV incidence in this age group for women was also high, at 19.8 per 100 person-years but was much lower in men at 3.6 per 100 person-years. (bmj.com)
  • The results show that the gloves may lose a limb during clinical use and should therefore be given greater emphasis to care when the instruments and materials handling sharps. (bvsalud.org)
  • Journal of Investigational Allergology and Clinical Immunology. (wikipedia.org)