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  • relapse
  • Research indicated that MBCT reduced risk of relapse or recurrence among patients who completed treatment with medications for depression. (medscape.com)
  • As per the latest literature, the interventions using Yoga and meditation including the mindfulness based cognitive therapy (MBCT) have been useful in treatment of depression and relapse prevention. (hindawi.com)
  • Relapse is the return of a depressive episode following a response but before recovery, whereas the term recurrence is used to describe the return of a depressive episode at some point after recovery. (cmeinstitute.com)
  • 8 Compared with patients whose depression is fully remitted, patients with incomplete remission have increased risk of relapse, 9 increased chronicity of depressive episodes with shorter durations between episodes, 9 impairments in workplace performance and social function, 10 and an increased risk of suicide. (cmeinstitute.com)
  • Efficacy
  • What is the efficacy of mindfulness based cognitive therapy (MBCT) in the treatment of major depressive disorder (clinical depression)? (medscape.com)
  • Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis. (mdedge.com)
  • ECT efficacy and treatment course: a systematic review and meta-analysis of twice vs thrice weekly schedules. (mdedge.com)
  • PURPOSE OF REVIEW The aim of this systematic review was to examine the efficacy and safety of second-generation antipsychotics (SGAs) in nonpsychotic major depressive disorder (MDD). (semanticscholar.org)
  • These statements may include statements regarding among other things the efficacy, safety and intended utilization of these investigational agents, our clinical and non-clinical plans, our plans to present or report additional data, the anticipated conduct and the source of future clinical trials, regulatory plans, future research and development and possible intended use of cash and investments. (seekingalpha.com)
  • Objective 1: To evaluate the efficacy of MST as a treatment for suicidal ideation and TRD in BPD. (clinicaltrials.gov)
  • approaches
  • Apart from limitations in terms of treatment, an important challenge in the research involving TRD is the limited knowledge and lack of clear and universally acceptable definitions which pose significant difficulties in operationalization, standardization, and generalization of the various treatment approaches for this important public health burden [ 5 ]. (hindawi.com)
  • alterations
  • Sacher J, Neumann J, Fünfstück T, Soliman A, Villringer A, Schroeter ML. Mapping the depressed brain: A meta-analysis of structural and functional alterations in major depressive disorder. (medscape.com)
  • medication
  • 12-17 Measurement-based care requires regularly monitoring symptom improvements, side effects, and medication adherence and using a treatment algorithm such as the one developed for the Texas Medication Algorithms Project (TMAP) to guide clinical decisions based on the results of the assessments. (cmeinstitute.com)
  • placebo
  • [ 165 ] There was a significant difference in depression rating scale score between, on one hand, the combined treatment group and, on the other, the sertraline-only (mean difference, 8.5 points), tDCS only (5.9 points), and placebo groups (11.5 points). (medscape.com)
  • After 8 weeks of treatment, mean HAM-D scores dropped by 10.9 points in the placebo-treated controls, 16.3 points in the low-dose PH10 group, and 17.8 points in the high-dose arm, said Dr. Liebowitz, also managing director and founder of the Medical Research Network . (mdedge.com)
  • hypothesis
  • Hypothesis 3: On neuroimaging tasks assessing emotion processing and cognitive functioning, patients receiving DBT+MST will show increased activity in bilateral DLPFC after treatment relative to pre-treatment baseline activation, and more activation in this region than patients in DBT without concurrent MST (DBT-only). (clinicaltrials.gov)
  • trials
  • 2 Although similar analyses of clinical trials of longer duration (12 weeks) have provided evidence that 6 weeks may be too short a duration to declare an antidepressant trial ineffective, 3 it is important to remember that spontaneous remission can occur over time. (psychiatrictimes.com)
  • The group has generated countless clinical reports and conducted numerous pilot studies and large controlled trials since its inception. (massgeneral.org)
  • Cedric will speak in detail about all of our ongoing clinical trials with these candidates shortly. (seekingalpha.com)
  • We have unveiled new internally generated product candidates and launched clinical trials in new indications. (seekingalpha.com)
  • It works closely with the MGH clinical and research programs, with the Clinical Trials Network and Institute (CTNI), and with translational programs such as the Psychiatric and Neurodevelopmental Genetics Unit (PNGU) and the Center for Genomic Medicine. (massgeneral.org)
  • Developments
  • Dr. Tabuteau will first provide a review of significant corporate and clinical developments and upcoming milestones, following that Dr. O'Gorman will provide an update on our ongoing late stage clinical programs and then Mr. Pizzie will review our financial results. (seekingalpha.com)
  • psychosocial
  • Evidence-based psychosocial treatments for child and adolescent depression. (medscape.com)
  • Often TRD is confused with some rather ill-defined terminologies like "difficult to treat depression'' (this generally refers to depression which because of its underlying psychopathology or psychosocial issues or due to nonadherence to treatment is not amenable to treatment) and "pseudoresistance'' (this generally refers to treatment failures due to inadequate dosages or inadequate duration of pharmacotherapy or nonadherence to treatment) [ 6 ]. (hindawi.com)
  • typically
  • Patients do not require anesthesia or sedation and remain awake and alert during treatment, a 40-minute outpatient procedure typically administered daily for four to six weeks. (ucsd.edu)
  • vagus
  • In this review article, we discuss various functions of the vagus nerve which make it an attractive target in treating psychiatric and gastrointestinal disorders. (frontiersin.org)
  • Treatments that target the vagus nerve increase the vagal tone and inhibit cytokine production. (frontiersin.org)
  • Vagus nerve stimulation for treatment of partial seizures: 1. (mdedge.com)