AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesHealth Care
RetrognathiaCleft PalatePalateMicrognathismPierre Robin SyndromeCleft LipPalate, HardPalate, SoftFacial PainMandibleCephalometryTemporomandibular Joint DisordersArthralgiaPhotographyVelopharyngeal InsufficiencyPalatal MusclesAbnormalities, MultipleMouth AbnormalitiesLingual FrenumTransforming Growth Factor beta3LipCraniofacial AbnormalitiesTeratogensMSX1 Transcription Factor
MicrognathiaGlossoptosisBifid uvulaHypertelorismCraniosynostosisVelopharyngeal insufficiencyCraniofacialPolydactylyMandibular retrognathiaAirway obstructionTongueHypoplasiaRoof of thSevereCongenitalUnilateralOccursSequenceSyndromesMultifactorialLateralInfantMalesMouthSurgeryLive birthsDevelopmentalHighChildrenInvolveFrequencyGeneticHardSymptomsSoftConditionPatientsPrimary
Micrognathia6
  • Micrognathia and retrognathia, cleft lip/palate, a poorly formed nose, posteriorly rotated ears and deep-set eyes are the main craniofacial dysmorphic features observed in HLS. (orpha.net)
  • Pierre Robin Sequence or Complex (pronounced "Roban") is the name given to a birth condition that involves the lower jaw being either small in size (micrognathia) or set back from the upper jaw (retrognathia). (ibis-birthdefects.org)
  • This syndrome resembles Pierre Robin sequence where there is a combination of cleft palate, retrognathia and micrognathia and presents with neonatal respiratory problems. (jpgo.org)
  • Pierre Robin syndrome is a developmental disorder characterized by micrognathia, glossoptosis and cleft palate. (symptoma.com)
  • Lenny is internationally renowned for his work in the treatment of children with craniofacial abnormalities, jaw deformities, jaw tumors, TMJ deformities, salivary gland disease, secondary cleft lip/palate deformities, obstructive sleep apnea, micrognathia and facial trauma. (issuu.com)
  • Congenital malformation characterized by micrognathia, glossoptosis and CLEFT PALATE. (wakehealth.edu)
Glossoptosis2
  • A rare congenital head and neck malformation characterized by the association of retrognathia and glossoptosis with or without cleft palate and respiratory obstruction. (globalgenes.org)
  • This rare syndrome presents the symptoms alliance to classical traid, U or V shaped cleft palate, microganathia/retroganathia, glossoptosis and associated anomalies of syndromes mainly with regard to respiratory and feeding problems .there are various advancement in the area of perinatal diagnosis of PRS, which help us to early identification and effective management .On the other hand physical diagnosis and cephalometric radiographs helps to manage postnatally. (ajner.com)
Bifid uvula2
  • Some children have cleft palate, bifid uvula and high arched palate. (jpgo.org)
  • Other characteristic features include widely spaced eyes (hypertelorism), eyes that do not point in the same direction (strabismus), a split in the soft flap of tissue that hangs from the back of the mouth (bifid uvula), and an opening in the roof of the mouth (cleft palate). (nih.gov)
Hypertelorism1
  • Other applications include corrections to birth defects (such as hypertelorism), maxillofacial surgery, craniosynostosis, rare craniofacial clefts, or removal of tumors. (wikipedia.org)
Craniosynostosis2
  • This can occur during surgery, where doctors fracture the face of a patient in order to correct craniofacial abnormalities such as cleft lip, Apert syndrome, Treacher Collins syndrome, Oligodontia, Cherubism, Crouzon syndrome, Pfeiffer Syndrome, Craniosynostosis, or Goldenhar Syndrome. (wikipedia.org)
  • A rare genetic multiple congenital anomalies/dysmorphic syndrome with characteristics of developmental delay, moderate to severe intellectual disability, dysmorphic features including craniosynostosis, micro/retrognathia, cleft palate, brachydactyly and short stature. (nictiz.nl)
Velopharyngeal insufficiency1
Craniofacial5
  • Craniofacial findings can include facial asymmetry, notched alae nasi, cleft lip and palate, and pointed chin. (nih.gov)
  • To compare the craniofacial features of Brazilian children who had received surgery for unilateral complete cleft lip and palate compared with non-cleft group. (bvsalud.org)
  • Although there are previous studies on craniofacial development and morphology in children with clefts, these studies lacked elucidation about the effect of primary surgery on craniofacial development in unilateral complete cleft lip and palate. (bvsalud.org)
  • A recent study concluded that operated unilateral complete cleft lip and palate children showed serious craniofacial deformities and the craniofacial growth was influenced especially in maxilla 8 , but no true consensus has been reached at this time about the influence of surgery on facial growth. (bvsalud.org)
  • Also, special thanks are extended to my stalwart collaborator, John F. Teichgraeber, MD, FACS, professor and director of the division of plastic and reconstructive surgery in the department of pediatric surgery at UTHealth McGovern Medical School, with whom I have been privileged to serve as co-director of the Texas Cleft-Craniofacial Clinic. (issuu.com)
Polydactyly2
  • Cleft lip/palate, polydactyly, especially double big-toe with club-feet, and the heart defect may also be visible. (orpha.net)
  • GLI3-related Pallister-Hall syndrome (GLI3-PHS) is characterized by a spectrum of anomalies ranging from polydactyly, asymptomatic bifid epiglottis, and hypothalamic hamartoma at the mild end to laryngotracheal cleft with neonatal lethality at the severe end. (nih.gov)
Mandibular retrognathia2
  • In the oropharynx, narrowing may be caused by an enlarged tongue, mandibular retrognathia (i.e., abnormal posterior positioning of mandible), excessive lymphoid tissue, large palantine tonsils, or redundant retroglossal folds. (cdho.org)
  • My ordeal involving my congenital mandibular retrognathia began in early childhood. (sailerclinic.com)
Airway obstruction1
  • Other definitions have been suggested, based on a combination of mandibular deficiency, presence of U-shaped or V-shaped cleft palate, and airway obstruction. (medscape.com)
Tongue5
  • This will allow the tongue to come down from the area between the sides of the palate. (ibis-birthdefects.org)
  • In a child without PRS, the tongue would come down and allow the palate to close fully. (ibis-birthdefects.org)
  • In a child with PRS, the tongue can't come down all the way and therefore the palate can not close. (ibis-birthdefects.org)
  • The secondary palate arises from the 2 palatal shelves, which are initially are in a vertical position because of the interposed tongue. (medscape.com)
  • With extension of the head at 7 weeks' GA and mandibular growth, the tongue is withdrawn, and the palatal shelves can swing into a more horizontal and midline position for fusion and formation of a hard and soft palate (see the following image). (medscape.com)
Hypoplasia1
Roof of th1
  • Common corrective procedures include intracranial surgeries (making room for brain growth through skull expansion), Cleft palate surgeries (repairing a gap in the roof of the mouth), and Cleft lip surgeries (closing a gap in the lips). (wikipedia.org)
Severe1
Congenital3
Unilateral5
Occurs3
  • However, the isolated cleft palate anomaly occurs with the same frequency as that in the general population. (medscape.com)
  • In contrast, cleft lip and/or palate occurs once in every 700 live births … Parents who have had one child with isolated Robin Sequence probably have between a 1 and 5% chance of having another child with this condition. (ibis-birthdefects.org)
  • Cleft palate occurs in 14-90% of the patients and it is usually seen in U-shaped form. (symptoma.com)
Sequence1
Syndromes2
Multifactorial1
Lateral3
  • Illustration depicts fusion of the lateral nasal, medial nasal, and maxillary prominences to form the primary palate. (medscape.com)
  • The overall development of the palate involves the formation of the primary palate followed by the formation of the secondary palate.At approximately 30-37 days' gestational age (GA), the primary palate forms by the growth and fusion of the medial nasal, lateral nasal, and maxillary processes (see the image below). (medscape.com)
  • Retrognathia, lateral view. (jpgo.org)
Infant1
  • The patient was a 18 y.o. white male refered by his orthodontist for evaluation of his residual cleft lip and palate following primary closure as an infant. (srt-psc.com)
Males1
Mouth1
  • A mouth palate measuring more than two standard deviations above the mean. (fdna.health)
Surgery2
  • Trauner's research focused on mandibular dysplasia, pre-prosthetic surgery, orthognathic surgery and cleft palate and lip surgery. (wikipedia.org)
  • The treatment of patients with cleft may begin soon after birth with the use of presurgical orthopedic apparatus, which the main objective is to assist the surgeon in cheiloplasty 4 (lip closure surgery, typically performed at 6 months of age) and palatoplasty 1 (closure of the palate surgery, usually performed after 12 months of age), although there are 171 clinical protocols for treating these patients 5 . (bvsalud.org)
Live births2
  • The mean incidence of cleft lip and palate is 2.1 cases per 1000 live births among Asians, 1 case per 1000 live births among white people, and 0.41 cases per 1000 live births among black people. (medscape.com)
  • The incidence of isolated cleft palate is constant among the 3 racial groups at 0.5 cases per 1000 live births. (medscape.com)
Developmental1
  • The knowledge of developmental dental disorders in cleft lip and palate children can provide valuable information for treatment planning at an early age 6-7 . (bvsalud.org)
High4
  • A high incidence of the cleft lip and palate is seen in North American populations of Asian descent, such as Indians of the southwestern United States and the west coast of Canada. (medscape.com)
  • A high arched palate is often present and clefting has also been noted. (arizona.edu)
  • What is a High Palate? (fdna.health)
  • In some instances a high palate may be one of the features of a rare disease or genetic syndrome. (fdna.health)
Children4
Involve1
  • Two thirds of all cases of clefting involve the lip with or without involvement of the palate, whereas one third of all cases occur as an isolated deformity of the palate. (medscape.com)
Frequency1
  • Most infants, but not all, will also have a cleft palate, but none will have a cleft lip … Frequency estimates range from 1 in 2,000 to 30,000 births, based on how strictly the condition is defined. (ibis-birthdefects.org)
Genetic1
Hard1
Symptoms1
Soft1
  • In the nasopharynx, narrowing may be due to hypertrophic adenoid tonsils, an elongated soft palate, and an elongated and edematous uvula. (cdho.org)
Condition1
Patients1
Primary2
  • The image below depicts embryonic formation of the primary palate. (medscape.com)
  • General opinion holds that mesodermal penetration underlies the formation of the primary palate. (medscape.com)