• orofacial clefts
  • Germline mutations in this gene have been described in families presenting syndromic diffuse gastric cancer and orofacial clefts. (springer.com)
  • This result, together with previous observations of co-occurrence of orofacial clefts and a variety of cancer types, suggests the need for replication studies testing rs1801552 in NSCL/P cohorts with a known cancer history. (springer.com)