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  • upper lip
  • A cleft lip contains an opening in the upper lip that may extend into the nose. (wikipedia.org)
  • The use of botulinum toxin injection to reduce the facial scar is logical because this could reduce the tensile distracting force of the upper lip caused by the orbicularis oris muscle pull. (clinicaltrials.gov)
  • For revision lip surgery, immediately after revision lip surgery 3 injection of 2.5U of botulinum toxin with a distance of 0.5 cm from each injection and operative wound are injected over both sides of upper lip in a adult on the operation room. (clinicaltrials.gov)
  • Study group II: For revision lip surgery, immediately after revision lip surgery 3 injection of 2.5U of botulinum toxin with a distance of 0.5 cm from each injection and operative wound are injected over both sides of upper lip in a adult on the operation room just after surgery. (clinicaltrials.gov)
  • orofacial clefts
  • Germline mutations in this gene have been described in families presenting syndromic diffuse gastric cancer and orofacial clefts. (springer.com)
  • This result, together with previous observations of co-occurrence of orofacial clefts and a variety of cancer types, suggests the need for replication studies testing rs1801552 in NSCL/P cohorts with a known cancer history. (springer.com)
  • surgery
  • A cleft lip or palate can be successfully treated with surgery. (wikipedia.org)
  • In some cases muscle tissue in the lip underneath the scar is affected and might require reconstructive surgery. (wikipedia.org)
  • Tollefson has demonstrate that botulinum toxin injection has decrease lip tension after primary lip repair in 3 children at 3-6 months of age The main aim of this randomized trial is to compare whether post-operative peri-surgical-injection of botulinum toxin into bilateral orbicularis oris muscles can improve scar formation for both primary and secondary cleft lip surgery. (clinicaltrials.gov)
  • Similar amount as group I (in C.C.) of normal saline will be injected after primary lip surgery at 3 months of age. (clinicaltrials.gov)
  • Similar amount (in C.C.) as Study Group II of normal saline will be injected after revision lip surgery (secondary cleft lip repair). (clinicaltrials.gov)