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  • moiety
  • OTA is composed of a 7-carboxy-5-chloro-8-hydroxy-3,4-dihydro-3- R -methylisocoumarin (ochratoxin α) moiety and a L- β -phenylalanine molecule, which are linked through the 7‑carboxy group by an amide bond. (mdpi.com)
  • The A ring is similar to a resorcinol moiety while the B ring is similar to a catechol moiety. (wikipedia.org)
  • The ability to quench singlet oxygen seems to be in relation with the chemical structure of catechin, with the presence of the catechol moiety on ring B and the presence of a hydroxyl group activating the double bond on ring C. Electrochemical experiments show that (+)-catechin oxidation mechanism proceeds in sequential steps, related with the catechol and resorcinol groups and the oxidation is pH-dependent. (wikipedia.org)
  • Arthropod cuticle consists of chitin linked by a catechol moiety to protein. (wikipedia.org)
  • strain
  • The 16S rDNA analysis revealed 99% nucleotide similarity to that of the type strain of R.rhodochrous (Fig. 2) ( 10 ). (kenyon.edu)
  • strain K‑804 [ 2 , 3 ] isolated from sorghum grain, and proved to be acutely toxic to Pekin ducklings, mice and rats [ 4 ]. (mdpi.com)
  • The Sphingomonas macrogolitabida strain TFA is a gram-negative bacterium that is able to grow on tetralin (1,2,3,4-tetrahydronaphthalene) as the only carbon and energy source ( 14 ). (pubmedcentralcanada.ca)
  • ligands
  • Extradiol members utilize ferrous iron as the active redox state, and this center is commonly coordinated octahedrally through a 2-His-1-Glu motif with labile water ligands occupying empty positions. (wikipedia.org)
  • cleave
  • 1,2-CTD uses Fe3+ as a cofactor to cleave the carbon-carbon bond between the phenolic hydroxyl groups of catechol, thus yielding muconic acid as its product. (wikipedia.org)
  • In contrast, 2,3-CTD utilizes Fe2+ as a cofactor to cleave the carbon-carbon bond adjacent to the phenolic hydroxyl groups of catechol, thus yielding 2-hydroxymuconaldehye as its product. (wikipedia.org)
  • species
  • Six species of free-living nitrogen fixing bacteria, Azomonas agilis, Azospirillum brasilense, Azospirillum lipoferum, Azotobacter chroococcum, Azotobacter vinelandii , and Beijerinckia mobilis , were surveyed for their ability to grow and fix N 2 using aromatic compounds as sole carbon and energy source. (springer.com)
  • catalytic
  • The catalytic mechanism of catechol 1,2-dioxygenase was elucidated using a combination of O18 labeling experiments and crystallography. (wikipedia.org)
  • 6-9 In particular, the manganese-dependent dioxygenase (MndD) is a system that has attracted much attention since its catalytic mechanism is still under discussion. (rsc.org)
  • degradative
  • in the degradative pathways of 2-aminobenzenesulphonic, benzenesulphonic and 4-toluenesulphonic acids in Alcaligenes sp. (wikipedia.org)
  • cyclic
  • Cyclic esters are formed upon treatment with phosphorus trichloride and phosphorus oxychloride, carbonyl chloride, and sulphuryl chloride: C6H4(OH)2 + XCl2 → C6H4(O2X) + 2 HCl where X = CO, SO2, PCl, P(O)Cl Catechols produce quinones with the addition of ceric ammonium nitrate (CAN). (wikipedia.org)
  • activity
  • However, the enzyme preparations from Brevibacterium and Arthrobacter have only the intradiol cleavage activity. (wikipedia.org)
  • iii) Lignin is a complex organic biopolymer mainly present in plants in close association with carbohydrates like cellulose and hemicellulose, its main activity is to provide plants with structural stability, impermeability and resistance towards microbial attack [ 3 ]. (ijbs.com)
  • Complex 1 displays the intradiol-cleaving dioxygenase activity, and the coordinate ethoxyl arm of the ligand is capable of accepting the proton from catechol, which mimics the function of Tyr447 in the. (diva-portal.org)
  • The spectrop h oto metric titration experiment indicates the relatively low demand of the external base (0.8 equiv based on Fe3+) for attaining the highest dioxygenase activity of complex 1. (diva-portal.org)
  • This hypothesis was supported by the results from enzyme assays of the crude cell extract of the consortium revealing catechol 1,2-dioxygenase activity which converted catechol and 4-chlorocatechol to cis,cis-muconic acid and 3-chloro-cis,cis-muconic acid respectively. (kent.ac.uk)
  • catechin
  • Catechol was first isolated in 1839 by Edgar Hugo Emil Reinsch (1809 - 1884) by distilling it from the solid tannic preparation catechin, which is the residuum of catechu, the boiled or concentrated juice of Mimosa catechu (Acacia catechu L.f). (wikipedia.org)
  • structural
  • The 3-methylcatechol structural motif is rare in natural products. (wikipedia.org)
  • This widespread structural motif is called the 2-His-1-carboxylate facial triad, and is found in many metalloproteins. (rsc.org)
  • At the center this barrel structure is a metal ion, most commonly ferrous iron, whose coordination environment is frequently provided by residues in two partially conserved structural motifs: G(X)5HXH(X)3-4E(X)6G and G(X)5-7PXG(X)2H(X)3N. (wikipedia.org)
  • further
  • Catechol dioxygenases are further classified as being "extradiol" or "intradiol," and this distinction is based on mechanistic differences in the reactions (figures 1 & 2). (wikipedia.org)
  • Chalcone is then isomerized to naringenin by chalcone isomerase which is oxidized to eriodictyol by flavonoid 3'- hydroxylase and further oxidized to taxifolin by flavanone 3-hydroxylase. (wikipedia.org)
  • reaction with dioxygen
  • 3-9 Although the reaction with dioxygen is thermodynamically favourable, the electronic configuration of the O 2 molecule creates a strong kinetic barrier that requires activation, which is useful to prevent any spontaneous reaction of O 2 with organic molecules. (rsc.org)
  • aromatic
  • Urushiols are naturally existing organic compounds that have the catechol skeleton structure and diphenol functionality but with alkyl groups substituted onto the aromatic ring. (wikipedia.org)
  • tryptophan
  • Purification and properties of tryptophan 2-monooxygenase. (qmul.ac.uk)
  • 5. Emanuele, J.J. and Fitzpatrick, P.F. Mechanistic studies of the flavoprotein tryptophan 2-monooxygenase. (qmul.ac.uk)
  • methyl
  • Its methyl ether derivative, guaiacol, converts to catechol via hydrolysis of the CH3-O bond as promoted by hydriodic acid. (wikipedia.org)
  • selective
  • Examples of recent gene duplication events in signaling as well as dioxygenase clusters are present, indicating selective gene family expansion as a relatively recent event in D. aromatica 's evolutionary history. (biomedcentral.com)
  • Cyclic
  • Cyclic esters are formed upon treatment with phosphorus trichloride and phosphorus oxychloride, carbonyl chloride, and sulphuryl chloride: C6H4(OH)2 + XCl2 → C6H4(O2X) + 2 HCl where X = CO, SO2, PCl, P(O)Cl Catechols produce quinones with the addition of ceric ammonium nitrate (CAN). (wikipedia.org)
  • structural motif
  • This widespread structural motif is called the 2-His-1-carboxylate facial triad, and is found in many metalloproteins. (rsc.org)
  • The 3-methylcatechol structural motif is rare in natural products. (wikipedia.org)
  • sequential
  • Construction of a monoanionic S,N,S-pincer ligand with a pyrrole core by sequential [1,2] phospho-Fries rearrangement. (growkudos.com)
  • iron
  • Dioxygenase Model Studies: Reactionof Oxygen with Iron Catecholates", Lauffer, R. B. (umn.edu)
  • Most mononculear iron dioxygenases are members of the cupin superfamily in which the overall domain structure is described as a six-stranded β-barrel fold (or jelly roll motif). (wikipedia.org)
  • At the center this barrel structure is a metal ion, most commonly ferrous iron, whose coordination environment is frequently provided by residues in two partially conserved structural motifs: G(X)5HXH(X)3-4E(X)6G and G(X)5-7PXG(X)2H(X)3N. (wikipedia.org)
  • In the 2OG-dependent dioxygenases, ferrous iron (Fe(II)) is also coordinated by a (His)2(Glu/Asp)1 "facial triad" motif. (wikipedia.org)
  • The active site of catechol dioxygenases most frequently contains iron, but manganese-containing forms are also known. (wikipedia.org)
  • carbon
  • Collectively these fungi are major inhabitants of forest biomass thus, playing a major role in carbon cycling and recycling of nutrients [ 1 , 2 ]. (ijbs.com)