• Types include: clear-cell adenocarcinoma of the vagina ovarian clear-cell carcinoma uterine clear-cell carcinoma clear-cell adenocarcinoma of the lung (which is a type of clear-cell carcinoma of the lung). (wikipedia.org)
  • Clear cell adenocarcinoma of the vagina and cervix were previously shown to be tumors occurring in female offspring exposed prenatally to diethylstilbestrol. (medscape.com)
  • Cancers from distant sites that metastasize to the vagina through the blood or lymphatic system also occur, including colon cancer, renal cell carcinoma, melanoma, and breast cancer. (medscape.com)
  • Cervical cancer happens when cells in the cervix, the lower part of the uterus that connects to the vagina, start to become abnormal. (mayoclinic.org)
  • Vaginal cancer is a disease in which malignant (cancer) cells form in the vagina. (vicc.org)
  • Cancer that forms in the thin, flat cells lining the inside of the vagina. (vicc.org)
  • Squamous cell vaginal cancer spreads slowly and usually stays near the vagina, but may spread to the lungs , liver , or bone. (vicc.org)
  • Glandular cells in the lining of the vagina make and release fluids such as mucus . (vicc.org)
  • Squamous cell carcinoma (SCC) of the vagina is linked to HPV infection and has many of the same risk factors as SCC of the cervix. (vicc.org)
  • A procedure to collect cells from the surface of the cervix and vagina. (vicc.org)
  • A piece of cotton, a brush, or a small wooden stick is used to gently scrape cells from the cervix and vagina. (vicc.org)
  • Then, a brush is inserted into the vagina to collect cells from the cervix. (vicc.org)
  • Having a human papilloma virus (HPV) infection, which can be linked to squamous cell carcinoma of the vagina. (mottchildren.org)
  • Women whose mothers took DES while pregnant have an increased risk of cervical cell abnormalities and of clear cell adenocarcinoma of the vagina and cervix. (oncolink.org)
  • People whose mothers took this drug during their pregnancy between the late 1940s and 1971 have an increased risk of clear cell adenocarcinoma of the vagina. (cancer.net)
  • The incidence of adenocarcinoma of the cervix is increasing within the US, but this diagnostic category is not typically associated with teenaged patients. (umn.edu)
  • And during these screenings, a provider collects cells from the cervix to be tested in the lab. (mayoclinic.org)
  • Cervical cancer is a disease in which cancer cells develop in the tissues of the cervix. (healthywomen.org)
  • Clear cell adenocarcinoma of the cervix with a concurrent polymerase-Ɛ (POLE) somatic mutation. (aarp.org)
  • In 1971, an epidemiologic study reported that the risk of development of a rare form of malignant vaginal and cervical cancer, clear cell adenocarcinoma (CCA), was related to intrauterine exposure to DES. (nih.gov)
  • Malignant glandular cells were detected on both conventional and Thin Prep™ gynecologic tests with histologic confirmation. (umn.edu)
  • A rare malignant, epithelial ovarian neoplasm, composed of clear, eosinophilic and hobnail cells displaying variable degrees of tubulocystic, papillary and solid histological patterns, macroscopically appearing as a typically unilateral mass in the ovary which ranges from solid to cystic. (cdc.gov)
  • Adenocarcinoma of the appendix accounts for 58% of malignant appendiceal tumors [ 2 ]. (gastrores.org)
  • According to WHO, adenocarcinoma of the appendix is defined as a malignant epithelial neoplasm of the appendix with invasion beyond the muscularis mucosa [ 2 ]. (gastrores.org)
  • Rosai-Dorfman Disease of the Breast with Variable IgG4+ Plasma Cells: A Diagnostic Mimicker of Other Malignant and Reactive Entities. (wustl.edu)
  • Patients with the following histologic epithelial ovarian cancer cell types are eligible: Serous adenocarcinoma, endometrioid adenocarcinoma, mucinous adenocarcinoma, undifferentiated carcinoma, clear cell adenocarcinoma, mixed epithelial carcinoma, transitional cell carcinoma, malignant Brenner's Tumor, or adenocarcinoma not otherwise specified (NOS). (astrazenecaclinicaltrials.com)
  • 28. Concordant clear cell "mesonephric" carcinoma of the bladder and lung adenocarcinoma with clear cell features - multiple primaries versus metastatic neoplasms: a case report. (nih.gov)
  • This case first appeared as Performance Improvement Program in Surgical Pathology (PIP) 2020, Case 29, and is metastatic prostatic adenocarcinoma found in a pre-sacral mass. (cap.org)
  • This is most consistent with a diagnosis of metastatic prostatic adenocarcinoma . (cap.org)
  • In general, it is not recommended to grade metastatic prostatic adenocarcinoma. (cap.org)
  • 25. Immunohistochemical profile of the penile urethra and differential expression of GATA3 in urothelial versus squamous cell carcinomas of the penile urethra. (nih.gov)
  • Most of the remainder are transitional cell carcinomas of the renal pelvis. (cancer.gov)
  • The purpose of this study is to understand the metabolism of cancers involving the kidney, including renal cell carcinomas and urothelial cell carcinomas, and how kidney cancers use different types of fuel to support tumor growth. (centerwatch.com)
  • Most (95%) vaginal malignancies are squamous cell carcinomas. (health.am)
  • Epithelial ovarian carcinomas can be broken down into many subtypes based on their cells' features. (moffitt.org)
  • others include primary and secondary adenocarcinomas, secondary squamous cell carcinomas (in older women), clear cell adenocarcinomas (in young women), and melanomas. (msdmanuals.com)
  • The appendiceal carcinomas are classified into adenocarcinoma, mucinous adenocarcinoma, singet-ring cell carcinoma, small cell carcinoma, and undifferentiated carcinoma [ 2 ]. (gastrores.org)
  • For the dose-escalation cohort: cancer relapsed or refractory to at least 1 prior standard care systemic regimen standard therapy with previous histological confirmation of diagnosis of fallopian tube, primary peritoneal, endometrial, cervical, prostate, non-small cell lung, esophageal, gastric, bladder, and renal cell carcinomas or melanoma. (astrazenecaclinicaltrials.com)
  • Background: Clear cell adenocarcinoma of the urethra (CCAU) is extremely rare and a number of clinicians may be unfamiliar with its diagnosis and biological behaviour. (netkumar1.co.in)
  • There has been scarce information about clear cell adenocarcinoma of the urethra (CCAU), an extremely rare type of cancer. (jocmr.org)
  • Clear cell adenocarcinoma of the urethra (CCAU), an extremely rare type of cancer, has been reported to occur more commonly in the female than in male [ 1 ]. (jocmr.org)
  • 22. Clear cell adenocarcinoma of the male urethra. (nih.gov)
  • 26. Clear cell adenocarcinoma of the male urethra in association with so-called nephrogenic metaplasia. (nih.gov)
  • 30. Clear cell adenocarcinoma of the urethra with inguinal lymph node metastases: A rare case report and review of literature. (nih.gov)
  • 32. Clear cell adenocarcinoma of the female urethra: magnetic resonance imaging. (nih.gov)
  • She underwent surgery and staging that revealed clear cell adenocarcinoma confined to the left ovary. (medscape.com)
  • Cite this: Clear Cell Adenocarcinoma of the Ovary Associated With In Utero Diethylstilbestrol Exposure: Case Report and Clinical Overview - Medscape - Jan 07, 2009. (medscape.com)
  • 40. Napsin A and WT 1 are useful immunohistochemical markers for differentiating clear cell carcinoma ovary from high-grade serous carcinoma. (nih.gov)
  • 1. Exploratory study of effective chemotherapy to clear cell carcinoma of the ovary. (nih.gov)
  • 2. Adjuvant chemotherapy with irinotecan hydrochloride and cisplatin for clear cell carcinoma of the ovary. (nih.gov)
  • 3. Pure-type clear cell carcinoma of the ovary as a distinct histological type and improved survival in patients treated with paclitaxel-platinum-based chemotherapy in pure-type advanced disease. (nih.gov)
  • 4. Clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy in stage III disease. (nih.gov)
  • 8. [Efficacy of chemotherapy for clear cell adenocarcinoma of the ovary]. (nih.gov)
  • 9. Progression-free survival and overall survival of patients with clear cell carcinoma of the ovary treated with paclitaxel-carboplatin or irinotecan-cisplatin: retrospective analysis. (nih.gov)
  • 10. Long-term survival in patients with clear cell adenocarcinoma of ovary treated with irinotecan hydrochloride plus cisplatin therapy as first-line chemotherapy. (nih.gov)
  • 11. Clinical characteristics of clear cell carcinoma of the ovary. (nih.gov)
  • 13. Less impact of adjuvant chemotherapy for stage I clear cell carcinoma of the ovary: a retrospective Japan Clear Cell Carcinoma Study. (nih.gov)
  • 14. Lack of effective systemic therapy for recurrent clear cell carcinoma of the ovary. (nih.gov)
  • Small changes in the cell DNA tells them to multiply out-of-control, and cells accumulate in growths called tumors. (mayoclinic.org)
  • Renal cell cancer is one of the few tumors in which well-documented cases of spontaneous tumor regression in the absence of therapy exist, but this regression occurs rarely and may not lead to long-term survival. (cancer.gov)
  • however, the two cell types may occur together in some tumors. (cancer.gov)
  • Some investigators have found that granular cell tumors have a worse prognosis, but this finding is not universal. (cancer.gov)
  • One of the rarest forms of ovarian cancer, this subtype is characterized by tumors with abnormal mucus-secreting cells. (moffitt.org)
  • Clear cell tumors of the lung are rare benign pulmonary neoplasms that contain an abundant amount of glycogen. (radiopaedia.org)
  • It is often classified under the spectrum of p erivascular epithelioid cell tumors (PEComas) . (radiopaedia.org)
  • 2. Liebow AA, Castleman B. Benign clear cell ("sugar") tumors of the lung. (radiopaedia.org)
  • A high-grade endometrial adenocarcinoma characterized by the presence of large neoplastic cells that display at least focal cytoplasmic clearing. (beds.ac.uk)
  • Clear cell adenocarcinoma present exclusively within endometrial polyp: report of two cases. (beds.ac.uk)
  • Late recurrence of a uterine clear cell adenocarcinoma confined to an endometrial polyp: case report. (beds.ac.uk)
  • Endometrial clear cell adenocarcinoma diagnosed by endometrial cytological examination: two cases report. (beds.ac.uk)
  • Endometrial cancer (also referred to as corpus uterine cancer or corpus cancer) is the most common female genital cancer in the developed world, with adenocarcinoma of the endometrium the most common type. (medscape.com)
  • 29. Female urethral adenocarcinoma: evidence for more than one tissue of origin? (nih.gov)
  • Biopsy specimens showed urethral adenocarcinoma that was positive for prostate-specific antigen. (biomedcentral.com)
  • We report a significantly rare case of a female patient with urethral adenocarcinoma arising from the Skene duct who presented with serum prostate-specific antigen (PSA) elevation. (biomedcentral.com)
  • The specimens revealed urethral adenocarcinoma with immunohistochemically positive staining for PSA. (biomedcentral.com)
  • Approximately 85% of renal cell cancers are adenocarcinomas, mostly of proximal tubular origin. (cancer.gov)
  • Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer. (nih.gov)
  • 7. Advanced stage clear-cell epithelial ovarian cancer: the Hellenic Cooperative Oncology Group experience. (nih.gov)
  • Ovarian clear cell carcinoma (OCCC) is one of the rare subtypes of ovarian cancer, yet its prognosis is extremely poor. (centerwatch.com)
  • In either case, ovarian cancer most commonly develops in the epithelial cells, which are in the outer surface tissue of the ovaries or fallopian tubes. (moffitt.org)
  • Because it develops in the tissue lining of the ovaries or fallopian tubes, epithelial ovarian cancer is also classified as a carcinoma, as opposed to cancer that develops in the blood, lymphatic cells, or other parts of the body. (moffitt.org)
  • Low-grade serous carcinoma, the fourth most common type of ovarian cancer, typically has slower-growing cancer cells than high-grade serous ovarian cancer. (moffitt.org)
  • Also called "clear cell adenocarcinoma," this is a rare type of epithelial ovarian cancer in which the cells look clear when viewed under a microscope. (moffitt.org)
  • Cancer that begins in glandular cells. (vicc.org)
  • Different cells called columnar (or glandular) cells line the cervical canal. (healthywomen.org)
  • The remainder include primary and secondary adenocarcinomas, secondary squamous cell carcinoma (in older women), clear cell adenocarcinomas (in young women), and melanoma. (health.am)
  • A report on a case of a 19-year-old woman, with no history of diethylbestrol exposure in uteri, diagnosed with clear-cell endocervical adenocarcinoma is made. (umn.edu)
  • International Endocervical Adenocarcinoma Criteria and Classification (IECC): A New Pathogenetic Classification for Invasive Adenocarcinomas of the Endocervix. (beds.ac.uk)
  • This could include a punch biopsy that collects tiny samples of cells, or an endocervical curettage that uses a narrow instrument to take an internal tissue sample. (mayoclinic.org)
  • Strikingly, our analysis highlight similarities between stem cell and cancer proteostasis, and diametrically opposed chaperome deregulation between cancers and neurodegenerative diseases. (biorxiv.org)
  • Specific tumour suppressor genes with promoter methylation in ovarian clear cell adenocarcinoma (OCCA) can be one important epigenetic mark distinguishing OCCA from ovarian serous adenocarcinoma (OSA), benign endometriotic cysts and normal ovarian epitheliums. (nih.gov)
  • Its name includes "serous" because, in this type of cancer, the malignancy develops in the serous membrane of the epithelial layer of cells lining the patient's abdominopelvic cavity. (moffitt.org)
  • The histological diagnosis was Skene adenocarcinoma based on the results of immunohistochemical staining showing positivity for PSA, P504S, and cancer antigen 125. (biomedcentral.com)
  • My sister is 51 yrs old and just diagnosed with Stage IV Uterine Adenocarcinoma that has spread to both pelvic, vertebra & the shoulder. (cancer.org)
  • Patients with small cell carcinoma should have received a platinum-based combination regimen either as neoadjuvant, adjuvant or first-line treatment. (nih.gov)
  • Histologic examination shows glands with loss of surrounding basal cells. (cap.org)
  • This RFA, Follow-Up of Patients with DES-Associated Clear Cell Adenocarcinoma, is related to the priority area of cancer. (nih.gov)
  • Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. (uci.edu)
  • To assess changes in the number of circulating endothelial cells (CECs) following three days of treatment with olaparib, combination olaparib/cediranib, or standard platinum-based chemotherapy in women with recurrent platinum-sensitive ovarian, primary peritoneal, or fallopian tube cancer. (ucbraid.org)
  • HPV DNA tests examine the cell specifically for HPV that can lead to pre-cancer. (mayoclinic.org)
  • For more advanced cervical cancer, there's also chemotherapy, a drug that runs the body killing cancer cells in its path. (mayoclinic.org)
  • Radiation therapy uses high-powered beams with energy focused on the cancer cells. (mayoclinic.org)
  • There's also targeted drug therapy that blocks specific weaknesses present within the cancer cells. (mayoclinic.org)
  • And immune therapy, a drug treatment that helps your immune system recognize cancer cells and attack them. (mayoclinic.org)
  • Renal cell cancer, also called renal adenocarcinoma or hypernephroma, can often be cured if it is diagnosed and treated when still localized to the kidney and the immediately surrounding tissue. (cancer.gov)
  • Because most patients are diagnosed when the tumor is still relatively localized and amenable to surgical removal, approximately 75% of all patients with renal cell cancer survive for 5 years. (cancer.gov)
  • For more information, see Transitional Cell Cancer of the Renal Pelvis and Ureter Treatment . (cancer.gov)
  • The staging system for renal cell cancer is based on the degree of tumor spread beyond the kidney. (cancer.gov)
  • The American Joint Committee on Cancer (AJCC) has designated staging by TNM (tumor, node, metastasis) classification to define renal cell cancer. (cancer.gov)
  • Adenocarcinoma is more likely than squamous cell cancer to spread to the lungs and lymph nodes . (vicc.org)
  • This is linked to a rare form of vaginal cancer called clear cell adenocarcinoma. (vicc.org)
  • Histologically, the tumor consisted of atypical cells with eosinophilic cytoplasm and enlarged nuclei, forming cribriform, solid, or trabecular structures, which was similar to prostatic cancer. (biomedcentral.com)
  • This type of therapy uses drugs to stimulate a patient's immune system to better recognize and destroy cancer cells. (moffitt.org)
  • The Pap test looks for abnormal cell changes that may be mild, moderate or severe precancer or cancer. (healthywomen.org)
  • Screening is meant to find precancer cells and treat them before they progress to invasive cancer. (healthywomen.org)
  • 6. [Prognostic analysis of 88 patients with ovarian clear cell carcinoma]. (nih.gov)
  • The age of the 4 patients with adenocarcinoma was 48, 39, 84 and 86 years, respectively. (gastrores.org)
  • Methods: Patients with colorectal neoplasms who underwent en bloc resection with ESD were included in this study. (bvsalud.org)
  • 39. Renal papillary adenoma--a putative precursor of papillary renal cell carcinoma. (nih.gov)
  • Extraskeletal Ewing sarcoma/Primitive neuroectodermal tumor (PNET) is an aggressive small round blue cell tumor seen primarily in adolescents and young adults. (cap.org)
  • Clear-cell adenocarcinoma is a type of adenocarcinoma that shows clear cells. (wikipedia.org)
  • The line where the two cell types meet-called the squamocolumnar junction (SCJ) is part of the T-zone, and the normal change process of one cell type to another creates metaplastic cells. (healthywomen.org)
  • The cells are checked under a microscope for signs of disease. (vicc.org)
  • Recurrent disease following surgery or radiotherapy is measurable provided that 30 days have elapsed since treatment and that measurable disease exists outside the radiation port, or there is clear progression within the radiation port. (astrazenecaclinicaltrials.com)
  • The recovery of physiological functionality, which is commonly seen in tissue mimetic three-dimensional (3D) cellular aggregates (organoids, spheroids, acini, etc.), has been observed in cells of many origins (primary tissues, embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and immortal cell lines). (mdpi.com)
  • A rare cause of hemoptysis: benign sugar (clear) cell tumor of the lung. (radiopaedia.org)
  • Benign clear (sugar) cell tumor of the lung with CD1a expression. (radiopaedia.org)
  • 6. Jordá aragón C, Froufe sánchez A, Padilla alarcón J. [Benign clear cell tumor of the lung]. (radiopaedia.org)
  • We report a very rare case of Skene duct adenocarcinoma in a female patient with serum prostate-specific antigen elevation. (biomedcentral.com)
  • Acinar adenocarcinoma occurs predominantly in the posterolateral aspects (peripheral zone) of the prostate. (cap.org)
  • 35. Immunohistochemical analysis of clear cell carcinoma of the gynecologic tract. (nih.gov)
  • While it isn't perfectly clear what sparks the cervical cells to change their DNA, it is certain that human papilloma virus, or HPV, plays a role. (mayoclinic.org)
  • When a high-risk HPV infection lasts for years, it can lead to changes in the cervical cells, resulting in a precancerous lesion. (oncolink.org)