Therefore antibodies are produced in rabbit serum by injecting the antigen (antiforssman antibodies). (wikipedia.org)
In 1932, Paul and Bunnell discovered that serum from symptomatic patients had antibodies that agglutinate the red blood cells (RBCs) of unrelated species, the "heterophile antibodies. (medscape.com)
or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity. (lookformedical.com)
Forssman3
A new histo-blood group system was discovered, based on the identification of Forssman glycolipid antigen on human red blood cells. (ashpublications.org)
In analogy with histo-blood group A antigen, Forssman (Fs) antigen terminates with α3- N -acetylgalactosamine and can be used by pathogens as a host receptor in many mammals. (ashpublications.org)
Serological tests2
Other heterophile antigens are responsible for some diagnostic serological tests such as: Weil-Felix reaction for typhus fever Paul Bunnell test for infectious mononucleosis Cold agglutinin test in primary atypical pneumonia Chemically, heterophile antigens are composed of lipoprotein-polysaccharide complexes. (wikipedia.org)
Heterophile antigens are antigens of similar nature, if not identical, that are present in different tissues in different biological species, classes, or kingdoms. (wikipedia.org)
Usually different species have different antigen sets, but the hetereophile antigen is shared by different species. (wikipedia.org)
Antigens that exist in alternative (allelic) forms in a single species. (lookformedical.com)
Transplantation between genetically identical individuals, i.e., members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains. (lookformedical.com)
Gene3
In this experiment, we observed cytokine gene expression changes in Gallus gallus embryo after challenge with Delta SARS-CoV-2 RBD spike protein antigen, from a concentration of 10 µg/mL to a series of highly diluted forms in ethanol, along with controls. (openaccesspub.org)
Attogram and zeptogram level concentrations of the antigen showed consistently remarkable up-regulation of INF-α among different cytokine gene expressions. (openaccesspub.org)
INF-β gene expressions at the zeptogram level of the antigen showed consistent changes, although not so outstanding. (openaccesspub.org)
Studies1
The unexpected Fs antigen was confirmed in structural, serologic, and flow-cytometric studies. (ashpublications.org)
Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (lookformedical.com)
Sets1
We have also studied pre-and post- experimental combined sets of higher (10 µg/mL) and significantly lower antigen concentrations (attogram level). (openaccesspub.org)
Forms1
Some evidence confirms the paradoxical beneficial role of harmful antigens when used in highly diluted forms. (openaccesspub.org)
Antibody5
Antigen is a substances usually protein in nature and sometimes polysaccharide, that generates a specific immune response and induces the formation of a specific antibody or specially sensitized T cells or both. (microbiologyinfo.com)
A measure of the binding strength between antibody and a simple hapten or antigen determinant. (lookformedical.com)
It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. (lookformedical.com)
It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes. (lookformedical.com)
the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. (lookformedical.com)
Other heterophile antigens are responsible for some diagnostic serological tests such as: Weil-Felix reaction for typhus fever Paul Bunnell test for infectious mononucleosis Cold agglutinin test in primary atypical pneumonia Chemically, heterophile antigens are composed of lipoprotein-polysaccharide complexes. (wikipedia.org)
Similar1
Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS). (lookformedical.com)
Specific1
That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. (lookformedical.com)