Class core binding factor alpha 1 subunit. Medical search. Frequent questions

26S proteasome non-ATPase regulatory subunit 10 or gankyrin is an enzyme that in humans is encoded by the PSMD10 gene. (wikipedia.org)

Together, these proteins form one version of a complex known as core binding factor (CBF). (medlineplus.gov)
All of the proteins bind ATP and, consequently, all of them carry the classical Walker A (phosphate-binding loop or P-loop) and Walker B (Mg2+-binding aspartic acid) motifs. (embl.de)
The prototype of DEAD-box proteins is the translation initiation factor eIF4A. (embl.de)
Click on the protein counts, or double click on taxonomic names to display all proteins containing DEXDc domain in the selected taxonomic class. (embl.de)
The involvement of viral DNA-binding proteins in the regulation of virulence genes, transcription, DNA replication, and repair make them significant targets. (mdpi.com)
Like all other GTPases, Rho proteins act as molecular switches, with an active GTP-bound form and an inactive GDP-bound form. (embl-heidelberg.de)
The active conformation is promoted by guanine-nucleotide exchange factors, and the inactive state by GTPase-activating proteins (GAPs) which stimulate the intrinsic GTPase activity of small G proteins. (embl-heidelberg.de)
In particular, we propose that Arg 85 and Asn 194 are involved in binding G proteins and enhancing GTPase activity. (embl-heidelberg.de)
While mRNA of alfa subunits (HIFs- α) are not altered by exposure to hypoxia, alfa, but not beta, proteins are stabilized by hypoxia. (biomedcentral.com)
Mammalian Ric-8 proteins act as chaperones to regulate the cellular abundance of heterotrimeric G protein alpha subunits. (stanford.edu)
TA binding stabilizes breaks in the middle of transmembrane helices 6 and 7 that facilitate aGPCR coupling and activation of heterotrimeric G proteins. (stanford.edu)
These helix-turn-helix structure found in many proteins(transcription factors). (vigyansarovar.com)
Unlike HTH proteins, the actual DNA-binding motif of the HLH proteins is a stretch of about 13 "basic" amino acids adjacent to the HLH whose main role is in protein dimerization. (vigyansarovar.com)
Levels of proteins, including Cyt C, Bcl-2/BAX, and Nrf2 /HO-1-associated proteins, were determined by western blotting and immunofluorescence. (sdbonline.org)
Furthermore, GSOs protected cells against GLU-induced apoptosis by reducing the expression of the mitochondrial apoptosis-associated Bcl-2 family effector proteins and protected cells from GLU-induced oxidative damage by increasing the nuclear translocation of Nrf2 and HO-1 expression. (sdbonline.org)
This highly complex 'protein biogenesis' process is assisted by a diverse network of folding catalysts and protein-modifying enzymes and is scrutinized by molecular chaperones and other 'quality control' factors which ensure that only correctly folded and assembled proteins exit the ER and proceed to distal compartments of the secretory pathway. (stanford.edu)
Proteins which bind to DNA. (lookformedical.com)
The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases. (lookformedical.com)
This family of proteins includes a wide variety of classes, including CYCLIN-DEPENDENT KINASES, mitogen-activated kinases, CYCLINS, and PHOSPHOPROTEIN PHOSPHATASES as well as their putative substrates such as chromatin-associated proteins, CYTOSKELETAL PROTEINS, and TRANSCRIPTION FACTORS. (lookformedical.com)
We show here that PLASTID REDOX INSENSITIVE 2 (PRIN2) and CHLOROPLAST STEM-LOOP BINDING PROTEIN 41 kDa (CSP41b), two proteins identified in plastid nucleoid preparations, are essential for proper plant embryo development. (frontiersin.org)
Each RNA polymerase requires the assistance of several other proteins or protein complexes, called general (or basal) transcription factors, which must assemble into a complex on the promoter in order for RNA polymerase to bind and start transcription. (stemcelldaily.com)
In this report, we conducted mass spectrometric analysis of the N-glycosylation profiles of recombinant spike proteins derived from four common SARS-CoV-2 variants classified as Variant of Concern, including Alpha, Beta, Gamma, and Delta along with D614G variant spike as a control. (cdc.gov)

The RUNX1 gene provides instructions for making a protein called runt-related transcription factor 1 (RUNX1). (medlineplus.gov)
Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells. (medlineplus.gov)
Eukaryotic TFIIH basal transcription factor complex helicase XPB subunit. (embl.de)
An ATP-dependent 3'-5' DNA helicase which is a component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. (embl.de)
40535) Transcription factor TFIIB cyclin-related protein CP001857 CDS Arcpr_0047 complement(40887. (go.jp)
This entry represents a zinc finger motif found in transcription factor IIs (TFIIS). (embl.de)
We show that radiation-induced migration/invasion occurs through the stabilization and nuclear accumulation of the transcription factor hypoxia-inducible factor 1 alpha (HIF1α), which drives the transcription of Junction-mediating and regulatory protein (JMY) 27 that stimulates GSC migration through its actin nucleation-promoting activity. (nature.com)
This gene encodes the GA-binding protein transcription factor, beta subunit. (nih.gov)
The TATA box is recognized by a transcription factor called TATA-binding protein (TBP), which is part of a larger complex called TFIID. (stemcelldaily.com)
Most promoters for RNA polymerase II also have a conserved sequence called the TATA box, which is recognized by a subunit of the transcription factor TFIID. (stemcelldaily.com)

A retinoblastoma-binding protein that is involved in CHROMATIN REMODELING, histone deacetylation, and repression of GENETIC TRANSCRIPTION. (lookformedical.com)
It is found as a subunit of protein complexes that are in involved in the enzymatic modification of histones including the Mi2 and Sin3 histone deacetylase complexes and the polycomb repressive complex 2. (lookformedical.com)
The chromo-domain binds histone H3 tails methylated on lysine 9. (cipsm.de)

18874) imidazoleglycerol phosphate synthase%2C cyclase subunit CP001857 CDS Arcpr_0021 19046. (go.jp)

Structurally, it contains a 33-amino acid ankyrin repeat that forms a series of alpha helices. (wikipedia.org)
The structural homology with the RecA recombination protein covers the five contiguous parallel beta strands and the tandem alpha helices. (embl.de)
The domain is composed of seven alpha helices. (embl-heidelberg.de)
The structure is an unusual arrangement of nine alpha-helices, the core of which includes a four-helix bundle. (embl-heidelberg.de)
The two amphipathic helices, particularly the highly conserved hydrophobic amino acids, are thought to mediate dimerization, which is a prerequisite to DNA binding. (vigyansarovar.com)
Finally, a number of side chains form a hydrophobic core between the α helices and thus must be hydrophobic. (vigyansarovar.com)

Mutations in pre-mRNA splicing factors including PRPF31 have been identified as cause for RP, raising the question how mutations in general factors lead to tissue specific defects. (uni-wuerzburg.de)
evm.model.tig00001501.4","tig00001501_g9219.t1","Cyanophora paradoxa","Pre-mRNA-processing factor 19 OS=Oryza sativa subsp. (ntu.edu.sg)
protein_coding" "Cz03g40300.t1","No alias","Chromochloris zofingiensis","Pre-mRNA processing factor 4 (PRP4)-like [Interproscan]. (ntu.edu.sg)
protein_coding" "Cz05g30030.t1","No alias","Chromochloris zofingiensis","mRNA splicing factor Cwf21 domain [Interproscan]. (ntu.edu.sg)
negative ATP by a common MAPK mRNA initiation 1. (evakoch.com)
A cleavage and polyadenylation specificity factor (CPSF) recognizes a polyadenylation signal (AAUAAA) on the pre-mRNA and cleaves it downstream of this signal. (stemcelldaily.com)

This study provides evidence that a switch-protein kinase regulatory network controls availability of σ 66 , the main sigma subunit for transcription in Chlamydia . (plos.org)
We show that ionizing radiation specifically enhances the motility and invasiveness of human GSCs through the stabilization and nuclear accumulation of the hypoxia-inducible factor 1α (HIF1α), which in turn transcriptionally activates the Junction-mediating and regulatory protein (JMY). (nature.com)
LysR substrate binding domain, Bacterial regulatory helix-turn-helix protein [Interproscan]. (ntu.edu.sg)
Protein conformation is critically linked to function and often controlled by interactions with regulatory factors. (cipsm.de)

Cheng A, Wan D, Ghatak A, Wang C , Feng D, Fondell JD, Ebright RH , Fan H. Identification and Structural Modeling of the RNA Polymerase Omega Subunits in Chlamydiae and Other Obligate Intracellular Bacteria. (academictree.org)
RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding. (academictree.org)
In eukaryotes the initiation of transcription of protein encoding genes by polymerase II (Pol II) is modulated by general and specific transcription factors. (embl.de)
Other transcription factors and RNA polymerase then assemble on the promoter to form a pre-initiation complex (PIC). (stemcelldaily.com)
RNA synthesis occurs in the 5' → 3' direction with the RNA polymerase catalyzing a nucleophilic attack by the 3-OH of the growing RNA chain on the alpha-phosphorus atom on an incoming ribonucleoside 5-triphosphate. (stemcelldaily.com)

The most commonly used assays are for the beta subunit of human chorionic gonadotropin (hCG). (medscape.com)

Like other transcription factors, the RUNX1 protein attaches (binds) to specific regions of DNA and helps control the activity of particular genes. (medlineplus.gov)
This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. (nih.gov)
Under hypoxic conditions activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. (abcam.cn)
Most PWD F4-positive ETEC are of the serogroup O149, whereas F18-positive ETEC belong to many serogroups, including O138, O139, O141, O147, and O157, because the F4 or F18 fimbriae gene cluster and enterotoxin genes are encoded on conjugative plasmids that result in their spread ( 1 ). (cdc.gov)

The structures, along with results from Ric-8 protein thermal stability assays and cell-based Galphaolf folding assays, support a requirement for the Galpha C-terminal region for binding specificity, and highlight that multiple structural elements impart specificity for Ric-8/G protein binding. (stanford.edu)
Cleavage/polyadenylation specificity factor, A subunit, C-terminal [Interproscan]. (ntu.edu.sg)

The ESCRT portion tends typically human for receptor-ligand transport that is fulfilment metabolized unidirectional binds. (erik-mill.de)
Using this approach, we obtained structures of neurotensin 1 receptor bound to antagonist SR48692, mu-opioid receptor bound to alvimopan, apo somatostatin receptor 2 and histamine receptor 2 bound to famotidine. (stanford.edu)
This study demonstrated that the Receptor for Activated C-Kinase 1 (RACK1) is important in SC function. (sdbonline.org)
These dimers collectively are that the TRAF6- and TRAF3-dependent chickens refer additional to happen at IPS-1, but to build later at Respiratory in receptor to not lead inward damage of nucleus I IFNs during RLH enhancing. (erik-mill.de)
C5b-8 defines as a binding receptor for C9. (erik-mill.de)
APOE associated to the LVP allows the initial virus attachment to cell surface receptors such as the heparan sulfate proteoglycans (HSPGs), syndecan-1 (SDC1), syndecan-1 (SDC2), the low-density lipoprotein receptor (LDLR) and scavenger receptor class B type I (SCARB1) (PubMed:12970454, PubMed:12356718, PubMed:12913001, PubMed:28404852, PubMed:22767607). (proteopedia.org)
E1/E2 heterodimer binding on CD81 activates the epithelial growth factor receptor (EGFR) signaling pathway (PubMed:22855500). (proteopedia.org)

This gene encodes a non-ATPase subunit of the 19S regulator. (wikipedia.org)
Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation. (embl-heidelberg.de)
This gene is highly expressed in fetal brain and encodes a protein of relative molecular mass 91K, named oligophrenin-1, which contains a domain typical of a Rho-GTPase-activating protein (rhoGAP). (embl-heidelberg.de)

The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling. (lookformedical.com)
In the GO, types of protein complexes are defined in terms of constituent macromolecule classes and the function(s) that the complexes carry out. (biomedcentral.com)

This protein interacts with another protein called core binding factor beta or CBFβ (produced from the CBFB gene), which helps RUNX1 bind to DNA and prevents it from being broken down. (medlineplus.gov)
The carboxy-terminal alpha-beta domain is structurally very similar to the proximal one even though it is bereft of an ATP-binding site, suggesting that it may have originally arisen through gene duplication of the first one. (embl.de)
Fragile X syndrome (FXS) is mostly caused by a CGG triplet expansion in the fragile X mental retardation 1 gene (FMR1). (uni-wuerzburg.de)
The primary data for 1-step growth, 2-step growth and gene expression summarized in Figs 4 and 5 are available in the S1 Dataset in the supplementary information. (plos.org)
Association of single nucleotide polymorphisms in the nuclear respiratory factor-2 beta subunit-encoding the GABPB1 gene within the occupational environment. (nih.gov)
Leucine zipper motifs are usually found as part of a DNA-binding domain in many transcription factors , and are therefore these motifs are involved in regulating gene expression . (vigyansarovar.com)

Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit (By similarity). (proteopedia.org)
Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by blocking the formation of phosphorylated STAT1 and promoting ubiquitin-mediated proteasome-dependent degradation of STAT1 (PubMed:23799612) (By similarity). (proteopedia.org)
Represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell cycle regulation (By similarity). (proteopedia.org)
Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NF-kappa-B activation, and activates AP-1 (By similarity). (proteopedia.org)
Diffusion of the complex E1/E2-EGFR-SCARB1-CD81 to the cell lateral membrane allows further interaction with Claudin 1 (CLDN1) and occludin (OCLN) to finally trigger HCV entry (PubMed:12970454, PubMed:24038151, PubMed:12913001, PubMed:20375010, PubMed:19182773) (By similarity). (proteopedia.org)

Chromatin assembly factor 1. (lookformedical.com)
Although initially discovered as a retinoblastoma binding protein it has an affinity for core HISTONES and is a subunit of chromatin assembly factor-1 and polycomb repressive complex 2. (lookformedical.com)
The repeating structural units of chromatin, each consisting of approximately 200 base pairs of DNA wound around a protein core. (lookformedical.com)

The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. (wikipedia.org)
ATPase, AAA-type, core [Interproscan]. (ntu.edu.sg)

Nucleic-acid-binding motif in transcriptional elongation factor TFIIS and RNA polymerases. (embl.de)
Elongation factor TS [Interproscan]. (ntu.edu.sg)

As of January 1, 2022, Oncotarget has shifted to a continuous publishing model. (oncotarget.com)

An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. (wikipedia.org)
High-resolution structures of GPR56 and LPHN3 in their active, G-protein-coupled states, reveal that after dissociation of the extracellular region, the decrypted TA peptides engage the seven-transmembrane domain core with a notable conservation of interactions that also involve extracellular loop 2. (stanford.edu)

The RUNX1: root injury strongly facilitates extent of the transcriptional value, forming process reaction cleavage 1( CD35)( Kim et al. (erik-mill.de)
recognition of CR1 on the mechanism of reviewed factor VOCs underpins to cleavage of Tregs( Torok et al. (erik-mill.de)

Low-resolution maps of the receptors in their N-terminal fragment-bound state indicate that the GAIN domain projects flexibly towards the extracellular space, keeping the encrypted TA peptide away from the seven-transmembrane domain. (stanford.edu)

The MutS requirements suppress with conformational enzymes binding other MLH and MutL, the later bind aromatic release family favour and catalytic cytokine to the MLH Canadians, widely eventually as RPA, EXO1, RFC, well long, and D-fructose less intrinsic lipids. (erik-mill.de)
Free beta subunits are degraded by macrophage enzymes in the kidney to make a beta subunit core fragment, which is primarily detected in urine samples. (medscape.com)

Molecular pathogenesis of core binding factor leukemia: current knowledge and future prospects. (medlineplus.gov)
A model is proposed where the relative levels of active antagonist (RsbV1) and switch-protein anti-sigma factor (RsbW) control the availability of σ 66 and subsequently act as a molecular 'throttle' for Chlamydia growth and development. (plos.org)
It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. (lookformedical.com)

The beta-hCG subunit is present in the syncytial layer of the blastomere. (medscape.com)
Beta-hCG and alpha-fetoprotein have proved to be useful markers for ovarian germ cell tumors. (medscape.com)

Recombinant fragment corresponding to Human HIF-1 alpha aa 300-550. (abcam.cn)

Translation initiation factor 1A / IF-1 [Interproscan]. (ntu.edu.sg)

hCG is present in the maternal circulation as either an intact dimer, alpha or beta subunit, and degraded form, or beta core fragment. (medscape.com)
Intact and free beta subunit are initially the predominant forms of hCG, with the beta core fragment emerging as the predominant form in the fifth week after conception. (medscape.com)
[ 3 ] Optimally, tests used for early pregnancy detection should be able to recognize all forms of intact hCG, including the free beta subunit and the beta core fragment. (medscape.com)
We show that Zld facilitates binding of the activator Bicoid and the gap repressors to this fragment, consistent with its proposed role as a pioneer protein. (bvsalud.org)

It also binds closely to the E3 ubiquitin ligase MDM2, which is a regulator of the degradation of p53 and retinoblastoma protein, both transcription factors involved in tumor suppression and found mutated in many cancers. (wikipedia.org)
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. (wikipedia.org)
protein_coding" "AAC74319","hns","Escherichia coli","global DNA-binding transcriptional dual regulator H-NS [Ensembl]. (ntu.edu.sg)

ATP binds to the amino proximal alpha-beta domain, where the Walker A (motif I) and Walker B (motif II) are found. (embl.de)
Therefore, entire motif comprising the DNA-binding basic region and the HLH is termed bHLH . (vigyansarovar.com)

Their binding properties depend on the amino acid sequence of the finger domains and of the linker between fingers, as well as on the higher-order structures and the number of fingers. (embl.de)
The free beta subunit of hCG differs from the others in that it has a 30-amino acid tailpiece at the COOH terminus. (medscape.com)
In general, transcription factors including this domain are dimeric, each with one helix that contains basic amino acid residues facilitate DNA binding. (vigyansarovar.com)

39504) translation initiation factor 2%2C alpha subunit CP001857 CDS Arcpr_0045 complement(39546. (go.jp)
54053) translation initiation factor eIF-1A CP001857 CDS Arcpr_0064 complement(54088. (go.jp)
Translation initiation factor SUI1 [Interproscan]. (ntu.edu.sg)

They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. (embl.de)
Zinc-binding motifs are stable structures, and they rarely undergo conformational changes upon binding their target. (embl.de)
Moreover, wogonoside promoted the expression of anabolic factors Sox-9, type two collagen and aggrecan while inhibiting the expression of catabolic factors such as matrix metalloproteinases (MMPs) and thrombospondin motifs 5 (ADAMTS-5) in mouse chondrocytes. (oncotarget.com)

Hypoxia-inducible factors (HIFs) are responsible for the transcriptional responses to hypoxic stress. (biomedcentral.com)

Moreover, PRIN2 and CSP41b form a distinct protein complex in vitro that binds DNA. (frontiersin.org)
In vitro , wogonoside decreased the production of pro-inflammatory cytokines like Nitric oxide (NO), prostaglandin E2 (PGE 2 ), tumor necrosis factor alpha (TNF-α), and interleukin-6 (IL-6). (oncotarget.com)

The toxin kinetics were predominantly triphasic with an early rise (phase-1), a plateau/decline (phase-2), and a final rapid rise (phase-3). (cdc.gov)

Transcription initiation at a consensus bacterial promoter proceeds via a 'bind-unwind-load-and-lock' mechanism. (academictree.org)
The consensus core of HRE sequence is 5′-RCGTG-3′ (where R is A or G). (biomedcentral.com)

Telomerase works the RNA -domain to dependent association of epidermal core lipids to the 3' G-rich heterotrimeric acid membrane. (erik-mill.de)

Mechanistically, we found that wogonoside inhibited nuclear factor kappa B/ hypoxia-inducible factor two alpha (NF-κB/HIF-2α) activation via the phosphatidylinositol 3 kinase (PI3K) /AKT pathway. (oncotarget.com)

The most-extensively studied core promoter element in eukaryotes is a short DNA sequence known as a TATA box, found 25-30 base pairs upstream from the start site of transcription. (stemcelldaily.com)

This is because cancer cells maintain high basal level of ROS, thus they are vulnerable to any further increase in ROS (Fig. 1 ). (degruyter.com)

Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication (PubMed:18033802). (proteopedia.org)

Specific protein-binding measures are often used as assays in diagnostic assessments. (lookformedical.com)

Glioblastoma (GBM) is the most common and aggressive type of primary brain tumor 1 . (nature.com)

These toxins bind to specific receptors of the intestinal epithelial cells and cause secretion of water and electrolytes into the intestinal lumen. (cdc.gov)

This entry represents the DNA-binding domain of classical SF1 and SF2 helicases. (embl.de)
Exoribonuclease, phosphorolytic domain 1 [Interproscan]. (ntu.edu.sg)
ARID DNA-binding domain [Interproscan]. (ntu.edu.sg)
FAD/NAD(P)-binding domain [Interproscan]. (ntu.edu.sg)
Oxidoreductase FAD-binding domain, Oxidoreductase NAD-binding domain, 2Fe-2S iron-sulfur cluster binding domain [Interproscan]. (ntu.edu.sg)
Tetratricopeptide repeat, Rubredoxin metal binding domain [Interproscan]. (ntu.edu.sg)

Twenty-four hours after plating on laminin substrate, TG1N and TG16 cells adopted a bipolar and elongated shape (Supplementary Fig. 1 B) and displayed high motility (mean velocities of 26.3 ± 0.6 µm/h and 25.7 ± 1.1 µm/h, respectively) without a predefined direction (Supplementary Fig. S1 C, Supplementary Movies S1 and S2 ), consistently with random motility pattern with high velocity previously reported for other GSC lines 30 . (nature.com)

Because this genetic change affects CBF, the condition is classified as core binding factor AML (CBF-AML). (medlineplus.gov)

Endogenous sex hormones and 111(1):167-177. (who.int)

Fusion with the host cell is most likely mediated by both E1 and E2, through conformational rearrangements of the heterodimer required for fusion rather than a classical class II fusion mechanism (PubMed:16533059, PubMed:29505618, PubMed:24698129). (proteopedia.org)

The proteasome and its subunits are of clinical significance for at least two reasons: (1) a compromised complex assembly or a dysfunctional proteasome can be associated with the underlying pathophysiology of specific diseases, and (2) they can be exploited as drug targets for therapeutic interventions. (wikipedia.org)
Here, we determined cryoelectron microscopy (cryo-EM) structures of Ric-8B in complex with Galphas and Galphaolf, revealing isoform differences in the relative positioning and contacts between the C-terminal alpha5 helix of Galpha within the concave pocket formed by Ric-8 alpha-helical repeat elements. (stanford.edu)
It provides unique identifiers, names and synonyms, list of complex members with their unique identifiers (UniProt, ChEBI, RNAcentral), function, binding and stoichiometry annotations, descriptions of their topology, assembly structure, ligands and associated diseases as well as cross-references to the same complex in other databases (e.g. (stanford.edu)
Taken together, our results suggest that PEP activity and consequently the switch from NEP to PEP activity, is essential during embryo development and that the PRIN2-CSP41b DNA binding protein complex possibly is important for full PEP activity during this process. (frontiersin.org)
Logical and semantic access to related protein forms is critical for advancing bioinformatics approaches to representing, modeling, and reasoning about complex biological systems at the genomic and cellular level [ 1 ]. (biomedcentral.com)

Anatomy4

Diseases4

Chemicals and Drugs18

Phenomena and Processes14

Information Science3

Proteasome non-ATPase regulatory subunit1

Proteins22

Transcription factor10

Histone3

Synthase1

Helices6

MRNA6

Regulatory4

Polymerase5

Human chorionic go1

Genes4

Specificity2

Receptor7

Encodes3

Protein complexes2

Gene6

Similarity5

Chromatin3

ATPase2

Elongation2

20221

Peptides2

Cleavage2

Peptide1

Enzymes2

Molecular3

Beta-hCG2

Recombinant1

Initiation factor 1A1

Fragment4

Regulator3

Motif2

Amino3

Translation initiation factor3

Motifs3

Transcriptional1

Vitro2

Predominantly1

Consensus2

Heterotrimeric1

Nuclear1

Sequence1

Basal1

Replication1

Assays1

Tumor1

Epithelial1

Domain6

Substrate1

Affects1

Endogenous1

Conformational1

Complex5