AcuteSTEMIIschemiaElevationIncident myocardial infarctionMortalityPatientsBiomarkersDiagnosis2001ArteryInfarct sizeIncidenceCardiac FunctionHeart FailureArrhythmiaSignificantlyMarkersRatsPreventionStudyCardiovascular Quality and OutcomesOccur2020AntioxidantAbnormalitiesIncreasesRuptureFindingsAbstract
Acute41
- In particular, acute myocardial infarction in the distribution of the circumflex artery is likely to produce a nondiagnostic ECG. (wikipedia.org)
- A normal ECG does not rule out acute myocardial infarction. (wikipedia.org)
- [ 2 ] In 1958, streptokinase was first used in patients with acute myocardial infarction (AMI), and this changed the focus of treatment. (medscape.com)
- Objective To assess the association between off-hour (weekends and nights) presentation, door to balloon times, and mortality in patients with acute myocardial infarction. (bmj.com)
- Study selection Any study that evaluated the association between time of presentation to a healthcare facility and mortality or door to balloon times among patients with acute myocardial infarction was included. (bmj.com)
- 36 studies reported mortality outcomes for 1 892 424 patients with acute myocardial infarction, and 30 studies reported door to balloon times for 70 534 patients with ST elevation myocardial infarction (STEMI). (bmj.com)
- Off-hour presentation for patients with acute myocardial infarction was associated with higher short term mortality (odds ratio 1.06, 95% confidence interval 1.04 to 1.09). (bmj.com)
- Conclusion This systematic review suggests that patients with acute myocardial infarction presenting during off-hours have higher mortality, and patients with STEMI have longer door to balloon times. (bmj.com)
- Acute myocardial infarction remains a leading cause of death worldwide. (bmj.com)
- 1 Every year, approximately one million people in the United States have an acute myocardial infarction and 400 000 die from coronary heart disease. (bmj.com)
- 2 Previous studies have suggested that patients with acute myocardial infarction who present to the hospital during off-hours (weekends and nights) may have higher mortality. (bmj.com)
- 4 8 9 Because of the high incidence and case fatality of acute myocardial infarction, small increases in the relative risk of mortality during off-hours can translate to important effects in the population. (bmj.com)
- Acute mitral regurgitation classically occurs with a spontaneous chordae tendineae or papillary muscle rupture secondary to myocardial infarction. (medscape.com)
- Studies evaluating intracoronary administration of adenosine for prevention of microvascular dysfunction and ischemic-reperfusion injury in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PCI) have yielded mixed results. (nih.gov)
- There is relatively little information available on recent population-based trends in the outcomes of patients who have had an acute myocardial infarction (AMI). (cmaj.ca)
- Despite multiple therapeutic advances in the treatment of acute myocardial infarction (AMI) over the past 2 decades (e.g., thrombolytics, β-blockers, aspirin, angiotensin-converting-enzyme inhibitors) AMI continues to be a leading cause of death throughout the industrialized world. (cmaj.ca)
- Background Men with gout have been found to have an increased risk of acute myocardial infarction (AMI), but no corresponding data are available among women. (bmj.com)
- Thus, we investigated the association between gout and risk of acute myocardial infarction (AMI) among elderly women (≥65 years) in British Columbia (BC), Canada. (bmj.com)
- Rapid, complete, and sustained reperfusion of the infarct-related coronary artery is a cornerstone in the treatment of acute ST-elevation myocardial infarction (STEMI). (dovepress.com)
- The present study was undertaken to evaluate the cardioprotective potential of HupA in myocardial ischemic damage using a rat model of acute myocardial infarction. (spandidos-publications.com)
- These findings suggest that the cardioprotective potential of HupA is associated with its antioxidant, anti-apoptotic and anti-inflammatory properties in acute myocardial infarction in rats. (spandidos-publications.com)
- Guo J, Li HZ, Wang LC, et al: Increased expression of calcium-sensing receptors in atherosclerosis confers hypersensitivity to acute myocardial infarction in rats. (spandidos-publications.com)
- β-blockers have been widely utilized as a part of acute myocardial infarction (AMI) treatment for the past 40 years. (benthamscience.com)
- β-blockers in hypertension, diabetes, heart failure and acute myocardial infarction: A review of the literature. (benthamscience.com)
- Harari R, Bangalore S. Beta-blockers after acute myocardial infarction: An old drug in urgent need of new evidence! (benthamscience.com)
- ST-elevation myocardial infarction (STEMI) following successful primary percutaneous coronary intervention (pPCI) is the leading cause of mortality and morbidity worldwide in major adverse coronary events (MACEs) due to mechanical complications, acute heart failure and cardiac shock after successful procedure. (bmj.com)
- Pre-race aspirin usage is prudent to reduce these events mediated by atherothrombosis based on conclusive evidence for prevention of first acute myocardial infarctions in same-aged healthy male physicians. (scirp.org)
- Rapid and correct diagnosis of acute myocardial infarction (AMI) plays a crucial role in saving patients' life. (hindawi.com)
- Acute myocardial infarction (AMI) is one of the leading causes for death worldwide, and it is the single largest cause of death in the United States, responsible for 1 out of every 6 deaths [ 1 , 2 ]. (hindawi.com)
- On the other hand, the number of circulating hEPC is increased in hypoxia or acute myocardial infarction (AMI). (intechopen.com)
- The current study quantitatively examined the reduction in risk of acute myocardial infarction (MI) occurrence following the legislations and the relationship with the corresponding smoking prevalence decrease. (biomedcentral.com)
- A growing body of evidence has suggested that the rate of acute myocardial infarction significantly decreased after the introduction of the smoking ban regulations, usually within a short time period. (biomedcentral.com)
- However, no single study has comprehensively evaluated the efficacy of TMZ in acute myocardial infarction (AMI) patients undergoing percutaneous coronary intervention (PCI). (hindawi.com)
- Acute myocardial infarction (AMI) may be accompanied by hyperglycemia, hepatic insufficiency, and renal failure [ 1 - 4 ]. (hindawi.com)
- Because of changes in human life rhythm and diet, the incidence of hyperglycemia and acute myocardial infarction is increasing. (hindawi.com)
- In addition, hyperglycemia has a significant negative impact on restenosis for acute ST-segment elevation myocardial infarction (STEMI) that underwent primary percutaneous coronary intervention (PPCI) [ 13 ]. (hindawi.com)
- Through this mechanism, TMZ is thought to correct disturbances in myocardial cellular homeostasis that result from acute ischemic damage and to protect against cardiomyocyte injury [ 14 , 15 ]. (hindawi.com)
- It's a new idea about how to look at the diagnosis of acute myocardial infarction," he says. (sentara.com)
- Sex Differences in Symptom Phenotypes Among Patients with Acute Myocardial Infarction is an analysis of the Variation in Recovery: Role of Gender on Outcomes of Young Acute MI Patients (VIRGO) multicenter registry. (sentara.com)
- Acute myocardial infarction is myocardial necrosis resulting from acute obstruction of a coronary artery. (msdmanuals.com)
- Acute MI includes both non-ST-segment-elevation myocardial infarction (NSTEMI) and ST-segment-elevation myocardial infarction (STEMI). (msdmanuals.com)
STEMI3
- Only patients with ST-segment elevation myocardial infarction (STEMI) receiving successful primary percutaneous coronary intervention (pPCI) and defined Δapelin-12 with apelin-12 elevation per cent 72 hours after pPCI compared with apelin-12 level immediately prior to pPCI were enrolled. (bmj.com)
- Several factors have been associated with an increased risk of developing ST elevation myocardial infarction (STEMI). (wikidoc.org)
- ST-segment elevation myocardial infarction (STEMI) is one of the highest-risk and highest-profile conditions we care for in the emergency department. (medscape.com)
Ischemia3
- Papillary muscle dysfunction usually is caused by myocardial ischemia or infarction. (medscape.com)
- 65 years of age with symptoms of depression but without evidence of myocardial ischemia. (medhelp.org)
- Myocardial stimulation produced by hydrALAZINE can cause anginal attacks and ECG changes of myocardial ischemia. (nih.gov)
Elevation6
- Prehospital ECG-based cardiac catheterization laboratory (CCL) activation for ST-segment-elevation myocardial infarction reduces door-to-balloon times, but CCL cancellations (CCL X ) remain a challenging problem. (ahajournals.org)
- We examined the reasons for CCL X , clinical characteristics, and outcomes of patients presenting as ST-segment-elevation myocardial infarction activations who receive emergent coronary angiography (EA) compared with CCL X . (ahajournals.org)
- The endpoints extracted were post-procedure residual stent thrombosis (ST) segment elevation and ST segment resolutions (STRes), difference in peak creatine kinase (CK-MB) concentration, thrombolysis in myocardial infarction (TIMI) grade III flow (TIMI 3 flow), myocardial blush grade (MBG) 3, mean difference in post-PCI ejection fraction (EF), all-cause mortality, cardiovascular mortality, heart failure (HF) and major adverse cardiovascular event (MACE). (nih.gov)
- We aimed to summarize the evidence from randomized clinical trials studies examining the efficacy of ischemic postconditioning (IPost) in ST-elevation myocardial infarction. (dovepress.com)
- TIMI 11B and ESSENCE were Phase III trials designed to test the efficacy of enoxaparin versus unfractionated heparin in patients with unstable angina/non-ST elevation myocardial infarction (MI). (acc.org)
- For non-ST-segment-elevation myocardial infarction, reperfusion is via percutaneous intervention or coronary artery bypass graft surgery. (msdmanuals.com)
Incident myocardial infarction2
- Our primary CVD outcome was defined by a combined end point that included either incident myocardial infarction, stroke, or heart failure. (lu.se)
- Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography. (cdc.gov)
Mortality3
- To evaluate the impact of the regionalised Integrated Cardiovascular Clinical Network (ICCNet) on 30-day mortality among patients with myocardial infarction (MI) in an Australian rural setting. (mja.com.au)
- As part of the Ontario Myocardial Infarction Database project the linked administrative data pertaining to these patients were used to examine cohort characteristics, cardiac procedures used and mortality rates for each of the 5 cohorts over time. (cmaj.ca)
- Five-year risk of cardiac mortality in relation to initial severity and one-year changes in depression symptoms after myocardial infarction. (medhelp.org)
Patients8
- Interestingly, post-infarction coronary angiography and coronary artery bypass grafting rates were consistently lower in the older and the female patients throughout the study period. (cmaj.ca)
- Low dose dobutamine echocardiography and myocardial contrast echocardiography were used to study patients before hospital discharge who had suffered a recent myocardial infarction and had a patent infarct-related artery (TIMI flow grade 3). (nih.gov)
- In patients with post-infarct dysfunctioning myocardium but a patent infarct-related artery, microvascular integrity, as assessed by myocardial contrast echocardiography, is an indicator of myocardial viability in terms of preserved contractile reserve, as demonstrated by dobutamine infusion and functional recovery at follow-up. (nih.gov)
- Patients receiving β-adrenergic blockers for an extended period following myocardial infarction have a higher chance of surviving. (benthamscience.com)
- Although many patients benefited from β-blockers, many do not, including those with myocardial infarction, left ventricle dysfunction, chronic pulmonary disease, and elderly people. (benthamscience.com)
- Beta-blockers in patients without heart failure after myocardial infarction. (benthamscience.com)
- For AMI patients undergoing PCI, TMZ reduced circulating biomarkers of myocardial infarction, reduced values of ALT, AST, and glucose, and improved cardiac function compared with the control group. (hindawi.com)
- John Brush Jr, MD, Sentara Cardiology Specialists, says his findings, published in the journal Circulation: Cardiovascular Quality and Outcomes , might explain why heart attacks are missed more often in women than in men and should encourage physicians to expand their thinking when it comes to diagnosing female patients. (sentara.com)
Biomarkers2
- Imaging tests such as stress radionuclide myocardial perfusion imaging or stress echocardiography can confirm a diagnosis when a person's history, physical exam, ECG and cardiac biomarkers suggest the likelihood of a problem. (wikipedia.org)
- For the end point infarct size, estimated by biomarkers of myocardial necrosis, an overall pooled effect was SMD =−0.58, 95% CI: −0.96 to −0.19. (dovepress.com)
Diagnosis2
- A diagnosis of myocardial infarction is created by integrating the history of the presenting illness and physical examination with electrocardiogram findings and cardiac markers (blood tests for heart muscle cell damage). (wikipedia.org)
- It should be determined if a person is at high risk for myocardial infarction before conducting imaging tests to make a diagnosis. (wikipedia.org)
20011
- Circulation, 2001. (medhelp.org)
Artery2
- In this manuscript, we focus on the broad aviation medicine considerations that are required to optimally manage aircrew with established coronary artery disease in those without myocardial infarction or revascularisation (both pilots and non-pilot aviation professionals). (bmj.com)
- 3 This is known as atherothrombosis and can lead to restricted blood flow through the artery, potentially causing myocardial infarction. (thrombosisadviser.com)
Infarct size1
- HupA significantly diminished the infarct size and inhibited the activities of myocardial enzymes, including creatine kinase (CK), the MB isoenzyme of creatine kinase (CK-MB), lactate dehydrogenase (LDH) and cardiac troponin T (cTnT). (spandidos-publications.com)
Incidence2
- The age-standardized myocardial infarction incidence rate was 73.3 per 100 000 in the whole country (95% CI: 72.3%-74.3%) and varied significantly from 24.5 to 152.5 per 100 000 across the 31 provinces. (who.int)
- Among cardiovascular diseases (CVDs), myocardial infarction (MI) accounts for majority of death and disability and has high incidence rate in both developed and developing countries as seen over the past quarter century (Agrawal et al . (scialert.net)
Cardiac Function1
- Heart failure (see the images below) may be caused by myocardial failure but may also occur in the presence of near-normal cardiac function under conditions of high demand. (medscape.com)
Heart Failure2
- In separate meta-analyses for each of the 3 CVD outcomes, 49 proteins were related to myocardial infarction, 34 to ischemic stroke, and 109 to heart failure. (lu.se)
- CONCLUSIONS: Protein profiling in multiple samples disclosed several new proteins to be associated with subsequent myocardial infarction, stroke, and heart failure, suggesting common pathophysiological pathways for these diseases. (lu.se)
Arrhythmia1
- Approximately 9 weeks later, a letter to the funeral director by the Chief's personal physician, stated "death was from plaque rupture in the coronary circulation leading to coronary thrombosis, myocardial infarction, and fatal arrhythmia. (cdc.gov)
Significantly1
- The results showed that a total of 278 proteins with significant changes were identified by quantitative proteomic analysis, of which 118 proteins were significantly upregulated and 160 proteins were significantly downregulated in myocardial tissue. (frontiersin.org)
Markers4
- Cardiac markers or cardiac enzymes are proteins that leak out of injured myocardial cells through their damaged cell membranes into the bloodstream. (wikipedia.org)
- Now, the markers most widely used in detection of MI are MB subtype of the enzyme creatine kinase and cardiac troponins T and I as they are more specific for myocardial injury. (wikipedia.org)
- In addition, a significant decrease in the activities of myocardial injury markers i.e., creatine phosphokinase-MB (CK-MB isoenzyme) and lactate dehydrogenase (LDH) was also observed in the heart of ISP control group as compared to sham control. (scialert.net)
- Of those, urokinase plasminogen activator surface receptor, adrenomedullin, and KIM-1 (kidney injury molecule 1) were also related to several markers of subclinical CVD in Prospective Investigation of Obesity, Energy production and Metabolism, reflecting myocardial or arterial pathologies. (lu.se)
Rats2
- Priscilla DH and Prince PS: Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats. (spandidos-publications.com)
- Isoproterenol was administered in rats to induce myocardial infarction. (scialert.net)
Prevention1
- 2006). Reduction of death incidences and prevention of myocardial infarction are of utmost importance. (scialert.net)
Study1
- In a cross-sectional study, data were collected on 20 750 new cases of myocardial infarction (ICD10 codes I21-22) admitted to hospitals and registered by the Iranian Myocardial Infarction Registry in 2012. (who.int)
Cardiovascular Quality and Outcomes1
- Originally published 17 Aug 2018 https://doi.org/10.1161/CIRCOUTCOMES.117.004464 Circulation: Cardiovascular Quality and Outcomes. (ahajournals.org)
Occur1
- In the US, about 1.0 million myocardial infarctions occur annually. (msdmanuals.com)
20202
- 2018. https://www.who.int/en/news-room/fact-sheets/detail/the-top-10-causes-of-death [accessed 26 Jun 2020]. (thrombosisadviser.com)
- Circulation 2012;126:2020-2035. (thrombosisadviser.com)
Antioxidant1
- The possible underlying mechanism of the cardioprotective effect of T. terrestris could be due to restoration of endogenous myocardial antioxidant status or free radical scavenging activity along with correction of the altered hemodynamic parameters and preservation of histoarchitectural and ultrastructural alterations. (scialert.net)
Abnormalities1
- New regional wall motion abnormalities on an echocardiogram are also suggestive of a myocardial infarction. (wikipedia.org)
Increases1
- Improved circulation increases blood flow to your muscles, which can shorten your recovery time and reduce muscle soreness (also known as delayed onset muscle soreness or DOMS). (healthline.com)
Rupture1
- Tendineae rupture can be due to endocarditis, myocardial infarction, or trauma. (medscape.com)
Findings1
- At autopsy, a pathologist can diagnose a myocardial infarction based on anatomopathological findings. (wikipedia.org)
Abstract1
- ABSTRACT Population-based data on myocardial infarction rates in the Islamic Republic of Iran have not been reported on a national or provincial scale. (who.int)