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  • Clocks
  • Despite predictions that circadian clocks would not be expressed by cells that are doubling faster than once per 24 hours, the cyanobacterial rhythms continue in cultures that are growing with doubling times as rapid as one division every 5-6 hours. (wikipedia.org)
  • In fact, everything you can measure in an organism follows a daily rhythm - a 24-hour cycle generated by internal clocks present in each and every cell in our bodies. (jewishindependent.ca)
  • While Amir's initial research interest was in circadian rhythm, over the last 10 years, he has expanded his focus to other clocks in the brain - those that control different types of behaviours and pathological conditions, such as depression, anxiety, drug addiction and diseases like Parkinson's. (jewishindependent.ca)
  • Mice
  • Mice with mutated versions of the gene are unable to maintain normal daily rhythms of sleep and wakefulness. (medicalnewstoday.com)
  • The mice also were engineered to contain a bioluminescent molecule that allowed the researchers to detect the circadian clock in pancreatic cells as a fluctuating glow. (redorbit.com)
  • Young mice lacking the BMAL1 gene only in their pancreas, however, had normal body weight and composition, and their behavior followed normal circadian patterns, although their blood sugar levels were abnormally high, the researchers found. (redorbit.com)
  • gene expression
  • We tested the hypothesis that circadian cycling is intrinsic to a unique class of SCN neurons by measuring firing rate or Period2 gene expression in single neurons. (pnas.org)
  • Here we demonstrate circadian rhythms in gene expression and firing rate from isolated SCN neurons and their subsequent identification by immunocytochemistry. (pnas.org)
  • Organization
  • This circadian clock is responsible for the temporal organization of a wide variety of functions, ranging from sleep and food intake, to physiological measures such as body temperature, heart rate and hormone release. (springer.com)
  • physiological
  • Circadian rhythms are daily observations in behavioural, physiological and metabolic processes," explained Dr. Shimon Amir, professor of psychology, Concordia University in Montreal, and director of the university's Centre for Studies in Behavioural Neurobiology. (jewishindependent.ca)
  • Physiological rhythms of patients with AD and FTD were then compared with a group of normal, elderly men (n = 8) from the community. (genomenewsnetwork.org)
  • Methods
  • METHODS: We studied the activity and core-body temperature rhythms in a cohort of 38 male patients with a clinical diagnosis of probable Alzheimer disease (AD) approximately 2 years before death. (genomenewsnetwork.org)
  • METHODS: We studied the response of the circadian system of 24 older men and women and 23 young men to scheduled exposure to ocular bright light stimuli. (genomenewsnetwork.org)
  • Vivo
  • Subsequent in vivo ( 13 ) and in vitro ( 8 , 14 ) results continue to support the idea that neurons from the dorsal and ventral SCN maintain daily rhythms. (pnas.org)
  • 19. Rhythms of inhibitory and excitatory output from the circadian timing system as revealed by in vivo microdialysis (A. Kalsbeek, R.M. Buijs). (elsevier.com)
  • brain
  • A 24-hour circadian rhythm controls nearly all brain and body processes, such as the sleep /wake cycle, metabolism, alertness and cognition, explained senior investigator Colleen McClung, Ph.D., associate professor of psychiatry, Pitt School of Medicine. (psychcentral.com)
  • Your circadian rhythm is basically a 24-hour internal clock that is running in the background of your brain and cycles between sleepiness and alertness at regular intervals. (sleepfoundation.org)
  • Chapter
  • ALG Online's Health & Performance chapter describes the impact of light on human health-including implications for the circadian system-and outlines the ways in which lighting design can address those influences. (constantcontact.com)