• A chyle fistula occurs when defect(s) of lymphatic vessel(s) result in leakage of lymphatic fluid, typically accumulating in the thoracic (pleural) or abdominal (peritoneal) cavities, leading to a chylous pleural effusion (chylothorax) or chylous ascites, respectively. (wikipedia.org)
  • Le chylothorax est une complication pr coce (de la premi re semaine, m me si on a pu en d crire d'authentiques apr s un mois, voire cent jours de d lai). (heartandcoeur.com)
  • Chylothorax, the presence of chyle in the pleural cavity resulting from the leakage of chyle from a damaged thoracic duct or from transdiaphragmatic passage of chylous ascites. (heartandcoeur.com)
  • En 1875, H. Quinke a d crit le premier chylothorax traumatique. (heartandcoeur.com)
  • Localization of chyle leakage site in postoperative chylothorax by oral administration of I-123 BMIPP. (semanticscholar.org)
  • Lymphoscintigraphy by oral administration of I-123 BMIPP is thought to be a useful method for localization of chyle leakage in patients with chylothorax induced by thoracic surgery. (semanticscholar.org)
  • When chyle can't get into the blood as it should, it can collect around one or both lungs and form a chylothorax. (kidshealth.org)
  • Chylothorax, the accumulation of chyle in the pleural space, is a relatively rare cause of pleural effusion in children. (aappublications.org)
  • Chylothorax, the accumulation of chyle in the pleural space, occurs after disruption of the thoracic duct. (aappublications.org)
  • who was diagnosed with CHYLOTHORAX (chyle leakage into the chest cavity) in May and must be on a low-fat diet (less than 10%, but preferably around 6 or 7). (dogfoodadvisor.com)
  • Chyle is transported via the intestinal lymphatics to the cisterna chyli (which is located in the retrocrural space at approximately the level of the L1/L2 vertebral body) and then ascends in the thoracic duct. (heartandcoeur.com)
  • Alternatively, sudden compression of the lipemic and engorged mesenteric lymphatics, adjacent nodes, and lower thoracic duct aggravated by deformations associated with stretching and tearing motions may also directly disrupt chyle containing lymphatics (6). (freethesaurus.com)
  • The thoracic duct is the largest lymphatic vessel in the body, draining lymph and chyle from the subdiaphragmatic body, left arm and chest (except for the lower lobe of the left lung) into the left brachiocephalic vein. (freethesaurus.com)
  • Possible explanations for the port incision chyle leakage are obstruction of the thoracic duct, which induced retrograde drainage of the lymphoid fluid, or an aberrant collateral branch of the thoracic duct in the chest wall. (biomedcentral.com)
  • Background: Thoracic chyle leakage is a major complication of esophagectomy. (uu.nl)
  • Scintigraphic finding was well correlated with the subsequent thoracoscopic observation, showing chyle leakage from a lymphatic tributary near its confluence to the thoracic duct at the level of the azygos continuation. (semanticscholar.org)
  • 1 The thoracic duct transports between 1.5 and 2.5 L of chyle daily (maximum 4 L/day in a healthy adult). (aappublications.org)
  • Damage to the thoracic duct causes the pleural space to accumulate chyle - lymphatic fluid enriched with fat (chylomicrons) absorbed by the intestinal cells and transported into the circulation via the thoracic duct. (mja.com.au)
  • Selective en masse ligation of the thoracic duct to prevent chyle leak after esophagectomy. (springer.com)
  • Chyle (from the Greek word χυλός chylos, "juice") is a milky bodily fluid consisting of lymph and emulsified fats, or free fatty acids (FFAs). (wikipedia.org)
  • Diagnosis of a chyle fistula may be accomplished by analysis of pleural/peritoneal fluid. (wikipedia.org)
  • Therefore, treatment of chyle fistulae relies upon either decreased production of lymphatic fluid to allow for healing of lymphatic defect(s) or permanent diversion of lymphatic fluid away from lymphatic defect(s). (wikipedia.org)
  • Identification of chyle is based on gross appearance, cytology Peritoneal fluid: cytology and presence of lipids. (vetstream.com)
  • Chyle is tissue fluid (lymph) that contains fat after it has been absorbed from the small bowel (intestine). (cancerresearchuk.org)
  • When this happens, lymph fluid or chyle can collect under the skin. (cancerresearchuk.org)
  • Chyle consists of lymph of intestinal origin, which is a milky and opalescent fluid rich in lymphocytes, protein, triglycerides and chylomicrons. (freethesaurus.com)
  • Chyle is a mixture of lymph from interstitial fluid and emulsified fat from intestinal lacteals. (journalcra.com)
  • A chlylothorax is when chyle (lymphatic fluid) collects in the space around a lung. (kidshealth.org)
  • If there is fluid, they'll test it to be sure it is chyle. (kidshealth.org)
  • 8 Chyle appears as a milky, opalescent fluid that separates into 3 layers upon standing: a creamy uppermost layer containing chylomicrons, a milky intermediate layer, and a dependent layer containing cellular elements, most of which are small lymphocytes. (aappublications.org)
  • Lymphatic fluid that contains fats is called chyle. (nationwidechildrens.org)
  • Chyle is a milky fluid made in the bowels (intestines) during digestion. (kidshealth.org)
  • If the fluid has chyle, they'll do other tests to find out how it's getting into the belly, such as an X-ray, ultrasound, CT scan, or MRI. (kidshealth.org)
  • It is made up of white blood cells which target bacteria, and chyle which is a fluid containing fats and proteins. (empowher.com)
  • Lymph fluid leakage - chyle leak. (royalmarsden.nhs.uk)
  • Less commonly, the vesicles are filled with milky fluid called chyle (KYE-ul). (kidshealth.org)
  • The fluid contains chyle, a milky fluid consisting of fat droplets. (clinicaltrials.gov)
  • Chyle leakage is a serious complication, with mortality ranging from 0 to 50%, due to significant loss of fluid, plasma protein, and immunoregulatory lymphocytes. (ctsnet.org)
  • A case of chyle fistula developing after nephrectomy for non-functioning kidney is reported, along with various management modalities. (springer.com)
  • The combination of the two therapies targets absorption and production of chyle , and has proven to be effective at our center, as we describe, with the management of one particularly high-output chylous fistula. (freethesaurus.com)
  • Recurrent high output chyle fistula post neck dissection resolution with conservative management. (semanticscholar.org)
  • Medicines and a low-fat diet can help the body make less chyle and make a leak more likely to heal. (kidshealth.org)
  • Chyle leak was the rarest complication in our ex- perience. (freethesaurus.com)
  • Chyle leakages treated by TPN first were significantly more severe compared with those treated first by low-fat diet, and were significantly associated with electrolyte deficiencies, increased complication severity, and length of stay, but not with 90-day mortality. (uu.nl)
  • Chyle leakage is a rare complication after laparoscopic cholecystectomy, with only one such case being previously reported in the English literature. (elsevier.com)
  • Chyle leakage can occur in 1 to 3 people in 100 when performing neck dissection, with the majority of these requiring resections of lymph nodes low in the neck on the left side. (royalmarsden.nhs.uk)
  • Incidence and management of chyle leakage after esophagectomy. (ctsnet.org)
  • From the lacteals, the chyle is transported to the cisterna chyli, which overlies the anterior surface of the second lumbar vertebra. (aappublications.org)
  • 4. The great trunks of the lacteals emerging from the mesenteric glands, and pouring their contents into (5) the receptacle of the chyle. (google.co.uk)
  • A 26-year-old Asian male was found to have chyle leakage from the port incision after video-assisted thoracoscopic surgery (VATS) for excision of pulmonary bullae. (biomedcentral.com)
  • The disruption site was ligated by video-assisted-thoracoscopic-surgery procedure with successful termination of the chyle leakage. (semanticscholar.org)
  • Using video-assisted thoracoscopic surgery (VATS), chyle leaking above the level of the right diaphragm was detected. (mja.com.au)
  • article{739fcc6b-cfa0-4f02-b948-9661e0451cb2, abstract = {The ability of chyle chylomicrons to bind prothrombin has been studied. (lu.se)
  • Chyle leaks: consensus on management? (freethesaurus.com)
  • Low-fat diet and TPN successfully treated 87% of chyle leaks. (uu.nl)
  • Conclusions: A step-up treatment strategy, starting with dietary modifications, solved nearly 90% of chyle leaks conservatively. (uu.nl)
  • A minority of chyle leaks required surgery. (uu.nl)
  • The chyle can't get into the blood, and instead leaks into other places. (kidshealth.org)
  • Sometimes chyle leaks into the space between the lungs and chest wall during surgery of the esophagus. (medlineplus.gov)
  • After visualization of the stomach and intestine, abnormal accumulation of the radiotracer was found initially around the right pulmonary hilum and then spread laterally in the upper pleural cavity, indicating chyle leakage in the region of the right pulmonary hilum. (semanticscholar.org)
  • Binding of prothrombin to chyle chylomicrons: effects of temperatuure and calcium ions, and role of surface phospholipids. (lu.se)
  • The ability of chyle chylomicrons to bind prothrombin has been studied. (lu.se)
  • Rat chyle chylomicrons were incubated with human 125I-prothrombin and binding was examined by separating the chylomicrons from free 125-I-prothrombin by density-gradient ultracentrifugation, and by gel filtration on Sepharose CL-2B. (lu.se)
  • A significant binding of prothrombin to chyle chylomicrons occurred. (lu.se)
  • Bound prothrombin could not be removed from chyle chylomicrons by treatment with EDTA, suggesting that this binding is not a simple Ca2+ dependent association between prothrombin and chyle chylomicrons. (lu.se)
  • It is suggested that the binding of prothrombin to chyle chylomicrons is in part mediated by negatively charged phospholipids of the chylomicron surface, although a specific role of the PE could not be demonstrated. (lu.se)
  • Chyle is principally derived from the lymphatic drainage of the gastrointestinal tract and contains a high concentration of triglycerides in the form of chylomicrons which give it a milky appearance. (heartandcoeur.com)
  • When accumulation of chyle causes a patient significant problems, such as shortness of breath and lung collapse, drainage through a thoracostomy tube or paracentesis may be necessary despite the obvious adverse effects that this form of therapy may produce. (medscape.com)
  • Il s'agit d'un panchement de chyle dans la pl vre la suite de la rupture du canal thoracique ( accumulation de liquide), appel chyle, autour d'un ou des 2 poumons. (heartandcoeur.com)
  • Differential cell count not always useful in recognizing chyle since lymphocytes are not always the predominant cell and some chylous effusions are dominated by neutophils and/or macrophages. (vetstream.com)
  • Chyle leakage can be confirmed by qualitative testing for the presence of chyle, the Sudan black test, and by dynamic lymphoscintigraphy. (biomedcentral.com)
  • Both the severity of the chyle leak and lymphoscintigraphy helped to predict the outcome of conservative treatment. (elsevier.com)
  • According to reported studies, postoperative chyle leakage generally has a more favorable outcome than that of chyle leakage from other causes. (elsevier.com)
  • To investigate the treatment of postoperative chyle leak after surgery for digestive malignancies . (bvsalud.org)
  • Nineteen cases of chyle leak were all identified between the second and the fourth postoperative day and were all initially managed with conservative treatment including early fasting , parenteral nutrition (PN), 24-hour continuous infusion of somatostatin , and low pressure suction drainage . (bvsalud.org)
  • Surgical closure of chyle leak was performed on the 11th postoperative day, abdominal cavity drainage tube was removed on the 4th postoperative day. (bvsalud.org)
  • Most postoperative chyle leak after surgery for digestive malignancies can be successfully managed with conservative treatment . (bvsalud.org)
  • Presence or absence of chyle in the urine helps to determine whether a disorder is hot or cold and this method of diagnosis is also extendable to the third-stage when the urine has undergone total transformation. (freethesaurus.com)
  • A diagnosis of chyle leakage from the incision was thus made. (biomedcentral.com)
  • more than 1,000 mL per day, with TPN, and 500 to 1,000 mL per day, with a low-fat diet or TPN depending on whether the chyle leakage was increasing or decreasing at diagnosis and the clinical condition. (uu.nl)
  • A substantial drainage of chyle can result in severe nutritional, metabolic, hemodynamic and immunologic derangement. (journalcra.com)
  • Ten patients had enteral nutrition (EN) and their drain tubes were repeatedly washed with 30 ml of compound meglumine diatrizoate injection every day until the drainage volume decreased to 200 ml/day. (bvsalud.org)
  • The dietitians' questionnaire examined knowledge and experience of chyle leakage, types of patients treated, dietary therapies employed, responsibilities for prescriptions and outcomes. (ovid.com)
  • The chyle leak resolved gradually with dietary manipulation. (elsevier.com)
  • 1] Because of the noninflammatory nature of chyle , patients do not experience pleuritic chest pain but present with dyspnea. (freethesaurus.com)
  • Contraindications to surgical correction of chyle fistulas are based on the patient's comorbidities and his or her ability to tolerate surgery. (medscape.com)
  • When chyle leak is not resolved with conservative treatment , surgical treatment should be considered to prevent serious complications . (bvsalud.org)
  • The initial signs included anorexia, colic, kicking at belly, paddling of limbs in recumbency, frequent getting up and lying down which subsided after 2 days which might be attributed to stimulation of autonomic nervous system distended cranial loops of obstruction with chyle and fluids (Papadopoulos et al. (freethesaurus.com)
  • This is usually managed conservatively with a low fat diet until leakage of the chyle has resolved. (royalmarsden.nhs.uk)
  • The lymphatic system normally brings chyle to a vein in the chest, where it enters the bloodstream. (kidshealth.org)
  • Lymph vessels take chyle to the bloodstream. (kidshealth.org)
  • This fatty lymph, called chyle, travels in lymph vessels to the bloodstream. (nccn.org)
  • and (3) Management of the chyle leakage to prevent the possible complications. (journalcra.com)
  • Chyle leakage incidence was 21%, consisting of 51% grade A and 49% grade B leakage. (uu.nl)
  • Dietitians at the Oxford Radcliffe Hospital encountering the problem of chyle leakage found a lack of information regarding its dietetic management. (ovid.com)
  • A link between the origin of chyle leakage and the effectiveness of conservative management became apparent from the literature review. (ovid.com)
  • Conservative management appears to be most effective in chyle leakage associated with head and neck surgery, and least effective when chyle leakage is associated with malignancy. (ovid.com)
  • More than 70% of respondents to the medical survey considered there to be a role for conservative management in the treatment of chyle leakage. (ovid.com)
  • The literature suggests that TPN may be the most effective treatment for reducing chyle flow. (ovid.com)
  • In this study our treatment strategy for chyle leakage was evaluated and its risk factors were identified. (uu.nl)
  • En bloc removal of the whole thymus, perithymic fatty tissue, both epiphrenic fat pads, and the sheets of right and left anterior mediastinal pleura is important for a radical resection of the tumor. (ctsnet.org)
  • From December 2008 to February 2012, in the Sun Yat-sen Memorial Hospital of Sun Yat-sen University , clinical data of 19 patients with chyle leak after digestive system cancer surgery were retrospective analyzed. (bvsalud.org)
  • The time to resolution of chyle leak in these ten patients ranged from 12 to 24 days. (bvsalud.org)
  • Four patients developed chyle leak. (urotoday.com)