AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth CareGeographicals
Schistosomiasis mansoniSchistosomiasisSchistosoma mansoniSchistosomicidesLiver Diseases, ParasiticSchistosomiasis japonicaOxamniquinePraziquantelParasite Egg CountSchistosomiasis haematobiaSplenic DiseasesAntigens, HelminthAntibodies, HelminthSchistosoma japonicumBiomphalariaNiridazoleAnthelminticsSchistosomaSchistosoma haematobiumSnailsDisease VectorsNeuroschistosomiasisGranulomaChronic DiseaseBurundiHepatomegalyEndemic DiseasesBrazilFecesHelminth ProteinsLung Diseases, ParasiticOvumMolluscacidesBulinusVenezuelaLiver CirrhosisEgyptPrevalenceHelminthiasisHypertension, PortalFresh WaterNeglected DiseasesMice, Inbred CBAEsophageal and Gastric VaricesNiclosamidePopulation DensityDNA, HelminthAntiplatyhelmintic AgentsSudanImmunoglobulin IsotypesCercariaSplenomegalyHelminthsTopography, MedicalParasitologyUrineSplenectomyEnzyme-Linked Immunosorbent AssayHost-Parasite InteractionsAcute DiseaseHookworm InfectionsImmunoglobulin GChinaEosinophilsSensitivity and SpecificitySkin Diseases, ParasiticLiverVaccinesCote d'IvoireBuffaloesTrichlorfonPest ControlTanzaniaParasitic DiseasesMaliGeographic Information SystemsSpleenZimbabweHycanthone
HaematobiumInfectionHuman schistosomiasisIntestinalContracted Schistosoma mansoniJaponicumControl of schistosomiasisPatients with acute schistosomiasisInfectionsPrevalenceBlood flukesParasiteAcute and chronicFlukesCases of schistosomiasisBilharziasisAfricaHepaticSpeciesPraziquantelSchistosomeBilharziaABSTRACT2017MalariaEndemic for schistosomiasisManagement of schistosomiasisEggsTropical and subtropicalMiracidiaMekongiMorbidityGranulomaClinicalUrinaryPuerto RicansLiverAsymptomaticSnailsTrematodePopulationsParasitic wormsKato-KatzEndemicityHepatosplenicTransmission dynamicsFibrosisSevereDiseaseSchistosomesExperimentalDiseasesManifestationsTreatment
Haematobium28
  • Most human schistosomiasis is caused by S haematobium, S mansoni , and S japonicum . (medscape.com)
  • Described from 2008 and published in a case report in 2019, a 14-year-old schoolboy from a Paris suburb visiting the Ivory Coast, his parents' native country, was found with hematuria and S haematobium-S mansoni hybrid infection. (medscape.com)
  • The spinal cord is more frequently affected in Schistosoma mansoni or S. haematobium infections. (who.int)
  • Ce sont les infections à Schistosoma mansoni ou à S. haematobium qui s'accompagnent le plus d'une atteinte de la moelle épinière. (who.int)
  • S. haematobium egg deposition has also been associated with damage to the female genital tract, causing female genital schistosomiasis that can affect the cervix, Fallopian tubes, and vagina and lead to increased susceptibility to other infections. (cdc.gov)
  • Disease is the result of ectopic deposition of eggs in the spinal cord ( S. mansoni or S. haematobium ) or brain ( S. japonicum ) and inflammatory reactions, typically the formation of granulomas that act as space occupying lesions. (cdc.gov)
  • Chronic symptoms vary with species but include bloody diarrhea (eg, with S. mansoni , S. mekongi , S. intercalatum , and S. japonicum ) or hematuria (eg, with S. haematobium ). (merckmanuals.com)
  • Adult Schistosoma worms live and copulate within venules of the mesentery (typically S. mekongi , S. intercalatum , S. japonicum and S. mansoni ) or bladder (typically S. haematobium ). (merckmanuals.com)
  • Among 100 Somali Bantu, 73% and 23% tested seropositive for schistosomiasis (primarily due to Schistosoma haematobium) and strongyloidiasis, respectively. (qxmd.com)
  • In the second case, a 15 year old male presented with LUTS for a 1 year duration and was diagnosed to have schistosomiasis after eggs of Schistosoma haematobium were found in his urine. (biomedcentral.com)
  • At least five known species infect humans, the three most common being Schistosoma haematobium , S japonicum , and S mansoni . (appliedradiology.com)
  • For example, S haematobium usually infects the urinary system, while S japonicum and S mansoni migrate and infect areas in the gastrointestinal tract. (appliedradiology.com)
  • 1 At this point, S haematobium migrates to the venous plexus of the bladder, while S japonicum and mansoni migrate to the venules in the small and large intestine. (appliedradiology.com)
  • Patients with a chronic infection caused by S haematobium most commonly present with hematuria, dysuria, urinary frequency, and suprapubic discomfort. (appliedradiology.com)
  • The main species causing schistosomiasis are Schistosoma mansoni , Schistosoma haematobium , and Schistosoma japonicum . (who.int)
  • Previously, it was generally assumed that in ancient populations schistosomiasis was primarily caused by S. haematobium, and that S. mansoni didn\'t become prevalent until Europeans appeared on the scene and introduced intensive irrigation schemes,\" Campbell Hibbs says. (world.edu)
  • Chronic lesions due to S. haematobium: hematuria, hydronephrosis, renal insufficiency, genital lesions, right heart decompensation due to pulmonary hypertension secondary to lung fibrosis. (wikitropica.org)
  • Schistosoma haematobium , S. mansoni and S. japonicum . (wikitropica.org)
  • Most human infections are caused by Schistosoma mansoni, S. haematobium, or S. japonicum. (farinelliandthekingbroadway.com)
  • Urogenital schistosomiasis is caused by Schistosoma haematobium and intestinal schistosomiasis by any of the organisms S. guineensis, S. intercalatum, S. mansoni, S. japonicum , and S. mekongi . (infontd.org)
  • In epidemiological studies, many data are conflicting with some reporting protective effects against malaria for Ascaris lumbricoides and Schistosoma haematobium while infection with hookworm or S. mansoni may increase the incidence of malaria and worsen pathology. (biomedcentral.com)
  • to obtain a better understanding of the possible influence of swamp rice farming on the patterns of schistosoma mansoni and schistosoma haematobium infections, the populations of two communities in rural liberia were studied. (liverpool.ac.uk)
  • during a study in kenya of the relationships between schistosoma haematobium infection and anemia and growth, evidence was found to suggest that this infection was associated with splenomegaly in children, and that both splenomegaly and hepatomegaly regressed in children treated for urinary schistosomiasis, compared with a placebo group. (liverpool.ac.uk)
  • attempts to induce resistance to schistosoma mansoni and s. haematobium in kenyan baboons (papio anubis) using non-specific immunostimulants. (liverpool.ac.uk)
  • We have now developed loop-mediated isothermal amplification (LAMP) assays for identifying Schistosoma mansoni and S. haematobium to facilitate large-scale evaluation of post-intervention transmission potential. (huji.ac.il)
  • Human schistosomiasis is caused by any of six species of blood flukes, namely Schistosoma mansoni , S. japonicum , S. haematobium , S. mekongi , S. intercalatum and S. guineensis [ 1 ]. (biomedcentral.com)
  • Urinary schistosomiasis caused by Schistosoma haematobium constitutes a major public health problem in many tropical and sub-tropical countries and is reportedly endemic in 53 counties in the Middle East and most of the African continent [ 10 11 ]. (ispub.com)
  • Urine samples were subjected to a point-of-care circulating cathodic antigen (POC-CCA) cassette test and a centrifugation method to check for both S. mansoni and S. haematobium infection, respectively. (researchsquare.com)
Infection40
  • The choice of sample to diagnose schistosomiasis depends on the species of parasite likely causing the infection. (cdc.gov)
  • however, many people are asymptomatic and have subclinical disease during both acute and chronic stages of infection. (cdc.gov)
  • In endemic areas, most infected people have the asymptomatic intestinal form detected during the chronic phase of infection [ 2 ]. (hindawi.com)
  • The infection induces both cellular and humoral responses that correlate with the acute and chronic form of the disease. (hindawi.com)
  • 8 ] speculated that IL-10 is important in regulating the human immune response to Schistosoma mansoni infection and that it is the main cytokine that plays part in the control of morbidity. (hindawi.com)
  • In the chronic phase of infection, forming phase 3, the Th2 response is moderated and granulomas, which form around newly deposited eggs, become smaller than they were earlier during the infection [ 3 ]. (hindawi.com)
  • Consequently, Th2-mediated responses are thought to be selectively advantageous to the human host in S. mansoni infection and perhaps other helminth infections [ 13 ]. (hindawi.com)
  • Objectives: The overall aim was therefore, to elucidate the impact of S. mansoni infection on protective T helper immune responses on P. falciparum and S. mansoni co-infection. (scirp.org)
  • Methodology: This study evaluated the T helper immune responses in individuals with independent S. mansoni infection, independent P. falciparum infection, co-infection and non-infection in school attending children in a co-endemic area along Lake Victoria shores, Uganda. (scirp.org)
  • S. mansoni infection is a major contributor of a reduced effective T helper immune response against P. falciparum in P. falciparum and S. mansoni co-infection. (scirp.org)
  • Schistosomiasis is infection with blood flukes of the genus Schistosoma , which are acquired transcutaneously by swimming or wading in contaminated freshwater. (merckmanuals.com)
  • Schistosomiasis is by far the most important trematode infection. (merckmanuals.com)
  • Forty-six percent reported chronic abdominal pain, which was not associated with either infection. (qxmd.com)
  • Occurrence of infection of a single host with multiple S. mansoni strains and inter- and intra-host genetic variations was observed. (ifremer.fr)
  • Substantial genetic diversity and gene flow across the S. mansoni population occurred at each site and non-human primates likely play a role in local transmission and maintenance of infection. (ifremer.fr)
  • Understanding S. mansoni genetic diversity and population structure of isolates from human and non-human primate hosts living in close proximity showed the occurrence of infection of a single host with multiple S. mansoni strains and inter- and intra-host genetic variations. (ifremer.fr)
  • It is estimated that 230 to 250 million people contract schistosomiasis annually, with infection ultimately resulting in 280,000 deaths per year. (appliedradiology.com)
  • Chronic infection can lead to various symptoms depending on the species of worm. (who.int)
  • Infection can cause anemia and chronic illness that impairs growth and cognitive development, damages organs, and increases the risk for other diseases. (world.edu)
  • The standing water collected by irrigation canals is particularly favorable to the type of snail that spreads the S. mansoni infection. (world.edu)
  • Acute schistosomiasis syndrome or "Katayama syndrome" a few weeks to months after primary infection (beginning of egg production). (wikitropica.org)
  • There are currently over 200 million people around the world living with schistosomiasis and an additional 780 million at risk of for infection. (experiment.com)
  • The fibrotic mechanism of S. mansoni infection tightly acorrelates with high IL-13 and low IFN-IL-10 [8]. (bet-bromodomain.com)
  • Nonetheless, it was surprisingly located that mice with targeted deletion with the P-selectin gene (PsKO mice) created unpolarized sort 1type two cytokine reactions and vigorously enhanced liver pathology following infection together with the kind 2-promoting S. mansoni [10]. (bet-bromodomain.com)
  • Omar, H.H., Impact of Chronic Schistosomiasis and HBV/HCV Co-infection on the Liver: Current Perspectives, Hepatic Medicine: Evidence and Research, 11, pp. 131-136, 2019. (itb.ac.id)
  • Chronic helminth infection causes immune hyporesponsiveness and stimulates anti-inflammatory cytokine production, which in turn modulates the host immune response to malaria. (biomedcentral.com)
  • we evaluated praziquantel for therapy of active schistosoma mansoni infection in 15 rural egyptian males with hepatosplenic schistosomiasis. (liverpool.ac.uk)
  • The present investigation explored the pathogenesis of the pulmonary changes that occur during the early phases of experimental Schistosoma mansoni infection, by taking advantage of the existence of a good mouse model for acute schistosomiasis 2 . (rsbmt.org.br)
  • Given the restricted distribution of Schistosoma mekongi in one province in Lao People's Democratic Republic (Lao PDR) and two provinces in Cambodia, together with progress of the national control programmes aimed at reducing morbidity and infection prevalence, the elimination of schistosomiasis mekongi seems feasible. (biomedcentral.com)
  • The present study was designed to investigate the potential complementary schistosomicidal and hepatoprotective activities of the methanol extract of Capparis spinosa L. (C. spinosa) with or without praziquantel (PZQ) and compare results with silymarin (Milk thistle), a known hepatoprotective and antifi brotic agent, on induced liver fi brosis by experimental Schistosoma mansoni (S. mansoni) infection. (cu.edu.eg)
  • The main objective of this study was to assess the prevalence and risk factors associated with Schistosoma (S.) mansoni infection among PSAC from Panamasso village, western Burkina Faso. (researchsquare.com)
  • Potential risk factors for S. mansoni infection were explored using multivariable logistic regression. (researchsquare.com)
  • The prevalence of S. mansoni infection as determined by Kato-Katz, formol-ether concentration, and POC-CCA was 42.1%, 39.5% and 80.7%, respectively. (researchsquare.com)
  • The geometric mean intensity of S. mansoni infection was 107.2 eggs per gram of faeces with 54.2%, 33.3%, and 12.5% of the children having light, moderate, and heavy infections, respectively. (researchsquare.com)
  • Girls (AOR = 2.9, 95% CI: 1.3-6.1), a household located within 500 m from the pond (AOR = 3.0, 95% CI: 1.0-8.6), or between 500 and 1000 m from the pond (AOR = 3.0, 95% CI: 1.2-7.2), and child's history of going to the pond (AOR = 5.0, 95% CI: 1.7-14.3) were the variables significantly associated with S. mansoni infection. (researchsquare.com)
  • The main morbidities due to S. mansoni infection in preschool-aged children (PSAC) i.e. under 6 years, are anemia, hepatosplenomegaly, and hepatic fibrosis with a higher risk in PSAC of age group 37-60 months (6). (researchsquare.com)
  • PSAC have been considered as a low risk group for S. mansoni infection (7,8), and are therefore so far excluded from various schistosomiasis control programs in Africa, resulting in a health inequity in affected people (9). (researchsquare.com)
  • Although several studies have reported prevalences of S. mansoni infection ranging from 0.9 to 86% in PSAC (6,10-19), the risk factors associated with this parasite infection remain poorly studied (11,12,14,16,20). (researchsquare.com)
  • In Burkina Faso, S. mansoni infection was endemic in the western and southern areas of the country with a focal distribution before the implementation of the national schistosomiasis control program (NSCP) in 2004 (21). (researchsquare.com)
  • In 2010, the prevalence of S. mansoni infection among SAC ranged from 3.3 to 39.1% with the highest prevalence (39.1%) recorded in Panamasso village (23). (researchsquare.com)
Human schistosomiasis3
Intestinal12
  • Hepatic schistosomiasis, or intestinal schistosomiasis. (wikipedia.org)
  • After malaria and intestinal helminthiasis, schistosomiasis is the third most devastating tropical disease in the world, being a major source of morbidity and mortality for developing countries in Africa, South America, the Caribbean, the Middle East, and Asia. (medscape.com)
  • Schistosoma mansoni is one of the causative agents of intestinal schistosomiasis and Plasmodium falciparum is the major causative agent of malaria. (scirp.org)
  • Infections with Schistosoma mansoni, S. japonicum, S. mekongi, and S. intercalatum are associated with intestinal lesions and chronic hepatic fibrosis. (wikitropica.org)
  • This parasite causes schistosomiasis mansoni and intestinal bilharziasis. (lookformedical.com)
  • Polyparasitism with intestinal parasites and schistosomiasis constitutes a major pubic health challenge in Nigeria especially among school age children. (ispub.com)
  • Using standard parasitological techniques, intestinal parasitic infections and urinary schistosomiasis were assessed among school age children in Edda a semi-urban area of south-eastern Nigeria. (ispub.com)
  • Polyparasitism with intestinal parasites and schistosomiasis is now globally recognized be the norm for many residents of parasite endemic regions and particularly among children of school age [ 1 2 3 4 ]. (ispub.com)
  • Intestinal parasitic infections and urinary schistosomiasis have been described as diseases of poverty and underdevelopment because they have been linked to lack of sanitation, lack of access to safe water and improper hygiene [ 12 ]. (ispub.com)
  • School age children in developing countries are the most severely affected by polyparasitism with intestinal parasites and schistosomiasis and continue to bear the greatest health burden due to the infections [ 4 14 ]. (ispub.com)
  • In Nigeria intestinal parasitic infections and urinary schistosomiasis continue to constitute a major pubic health and developmental challenge especially among school age children. (ispub.com)
  • Schistosomiasis is a major public health concern in sub-Saharan Africa (SSA) with around a third of the annual 192 million cases of schistosomiasis caused by S. mansoni , the causative agent of intestinal schistosomiasis (1). (researchsquare.com)
Contracted Schistosoma mansoni1
Japonicum2
  • S. mansoni and S. japonicum eggs most commonly lodge in the blood vessels of the liver or intestine and can cause diarrhea, constipation, and blood in the stool. (cdc.gov)
  • Schistosoma mansoni and S. japonicum primarily affect the intestine and liver, causing abdominal pain, diarrhea, and liver damage. (who.int)
Control of schistosomiasis1
  • This study provides insights into the epidemiology, genetic diversity and population structure of S. mansoni in human and non-human primates in Ethiopia, all of which are crucial for the control of schistosomiasis. (ifremer.fr)
Patients with acute schistosomiasis2
  • Of the 42 (37.2%) patients with acute schistosomiasis, measured from the last exposure to the onset of symptoms. (cdc.gov)
  • Dry cough, dyspnea and manifestations of bronchial asthma have recently been observed in patients with acute schistosomiasis. (rsbmt.org.br)
Infections10
  • Chronic inflammation can lead to bowel wall ulceration, hyperplasia, and polyposis and, with heavy infections, to liver fibrosis and portal hypertension. (cdc.gov)
  • Chronic infections may increase the risk of bladder cancer. (cdc.gov)
  • Suboptimal T helper immune responses were detected in independent S. mansoni infections characterized by significantly down regulated Th1 (Z = -1.425, p = 0.0313) response in comparison to the non-infected group. (scirp.org)
  • P. falciparum and S. mansoni infections initiate a T helper immune response [4] [5] , which links the innate and adaptive immune responses against the parasites. (scirp.org)
  • Finally, whatever the transmission site no genetic structure was observed between human and non-human primates, however, there appears to be little barriers, if any, host specificity of the S. mansoni populations with cross-host infections. (ifremer.fr)
  • RÉSUMÉ Une étude réalisée en Égypte a déterminé la prévalence des infections par les virus de l'hépatite B (VHB) et de l'hépatite C (VHC) chez les coiffeurs pour hommes ( n = 308) et leurs clients ( n = 308) dans le gouvernorat de Gharbia, et évalué les connaissances, les attitudes et les pratiques pendant la coupe de cheveux et le rasage. (who.int)
  • mansoni contamination does not skimp establishment regarding specialized medical health following a number of malaria infections, together with nonclassical monocytes seeming to experience a role. (jak-signaling.com)
  • Schistosoma mansoni, nematode infections, and progression to active tuberculosis among HIV-1-infected Ugandans. (farinelliandthekingbroadway.com)
  • Consequently, this study aimed to assess the possible expression of particular lymphocytes and platelets activation molecules in chronic HCV andor schistosomiasis mansoni infections and their possible roles in progression of CLD.patients with concomitant hepatic schistosomiasis mansoni and chronic HCV infections devoid of cirrhosis (17 males and 6 females). (bet-bromodomain.com)
  • In school-aged children (SAC) (i.e. 6-15 years), chronic infections with S. mansoni cause anemia, growth retardation and cognitive impairment (5). (researchsquare.com)
Prevalence3
Blood flukes2
Parasite7
  • This is caused by the parasite Schistosoma mansoni. (wikipedia.org)
  • Although many health measures have been carried out to limit parasite transmission, significant numbers of non-human primates such as Chlorocebus aethiops (Ch. aethiops) (vervet) and Papio anubis (baboon) are infected with S. mansoni, notably in Ethiopia, where they are expected to have potentially significant implications for transmission and control efforts. (ifremer.fr)
  • This thesis describes the synthesis of several glycans of these glycans present on the S. mansoni parasite, focusing mainly on the Circulating Anodic Antigen (CAA) and glycans bearing the unique α-(1-2)-L-Fucose-α-(1-2)-L-Fucose motifs. (universiteitleiden.nl)
  • After my PhD I carried out multi-locus genotyping on S. mansoni miracidia from Uganda, to analyse parasite diversity, heterozygosity and population structure and how they alter over time with PZQ exposure. (imperial.ac.uk)
  • Schistosomiasis is transmitted through contact with freshwater contaminated with the larvae of the parasite, released by freshwater snails. (who.int)
  • S. mansoni is also frequently recovered from wild primates in endemic areas but is considered primarily a human parasite and not a zoonosis. (farinelliandthekingbroadway.com)
  • Acute schistosomiasis is related to the migration of parasite larvae through the lungs and a rise in the host immune response towards parasite larvae, worms and eggs. (rsbmt.org.br)
Acute and chronic3
  • The cellular response pattern is associated with both the acute and chronic phases of the disease, in which cytokines play a critical role. (hindawi.com)
  • Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria. (universiteitleiden.nl)
  • Schistosoma can induce acute and chronic schistosomiasis. (appliedradiology.com)
Flukes2
  • Schistosomiasis is a chronic disease caused by flukes (trematodes). (ifremer.fr)
  • Schistosomiasis or bilharziasis (this terminology should be abandoned) is a disease caused by flatworms (trematodes or flukes). (wikitropica.org)
Cases of schistosomiasis1
Bilharziasis2
  • Sometimes referred to as bilharzias, bilharziasis, or snail fever, schistosomiasis was discovered by Theodore Bilharz, a German surgeon working in Cairo, who first identified the etiological agent Schistosoma hematobium in 1851. (medscape.com)
  • Schistosomiasis (Bilharziasis) is a parasitic infestation associated with a high degree of morbidity and mortality in third world countries, especially in Africa [ 1 ]. (biomedcentral.com)
Africa5
  • More than 140 million people, 90% of who live in Africa, are infected with schistosomiasis. (medscape.com)
  • Schistosoma mansoni and Plasmodium falciparum are co-endemic in Uganda and are the leading parasitic causes of public health problems across sub-Saharan Africa. (scirp.org)
  • Schistosomiasis is a chronic parasitic disease, that affects over 207 million people and causes over 200,000 deaths annually, mainly in sub-Saharan Africa. (ifremer.fr)
  • Schistosomiasis is a Neglected Tropical Disease that affects 200 million people every year, mostly in limited-resource communities in Africa and South Eastern Asia. (experiment.com)
  • Schistosomiasis remains a major public health concern in sub-Saharan Africa. (researchsquare.com)
Hepatic2
  • It can be associated with conditions such as portal hypertension, variceal hemorrhage, chronic hepatic encephalopathy, and hepatocellular carcinoma. (thieme-connect.com)
  • Therefore, treatment targeting hepatic fi brosis associated with schistosomiasis remains a challenging proposition. (cu.edu.eg)
Species4
  • We conclude that acute schistosomi- asis is a major clinical problem among travelers, diagnostic available at the Ministry of Health and uses a soluble egg and therapeutic options for acute schistosomiasis are limit- antigen ELISA (IVD Research Inc., Carlsbad, CA, USA) ed, and asymptomatic travelers returning from schistosomi- that is not species specific. (cdc.gov)
  • the species causing urogenital schistosomiasis [ 4 ]. (biomedcentral.com)
  • About 25 percent of mummies in the study dated to about 1,500 years ago were found to have Schistosoma mansoni, a species of schistosomiasis associated with more modern-day irrigation techniques. (world.edu)
  • S. mansoni was the sole species infecting a high proportion of PSAC in the study area. (researchsquare.com)
Praziquantel7
Schistosome1
Bilharzia3
  • Schistosomiasis, also known as Bilharzia, is a chronic, debilitating disease second only to malaria among human parasites in its socio-economic and public health importance. (imperial.ac.uk)
  • Schistosomiasis, also known as bilharzia, is a disease caused by parasitic flatworms called schistosomes. (who.int)
  • Ahmed, S.H., Schistosomiasis (Bilharzia) Treatment and Management, https://emedicine.medscape.com/article/228392-treatment , 22 December 2020. (itb.ac.id)
ABSTRACT1
20172
  • The World Health Organization (WHO) estimates that about 220.8 million people required preventive treatment for schistosomiasis in 2017. (medscape.com)
  • Geneva: World Health Organisation, https://www.int/schistosomiasis/resources/9789241511995/en/ , 2017. (itb.ac.id)
Malaria4
Endemic for schistosomiasis1
Management of schistosomiasis2
  • This paper describes the clinical manifestations, diagnosis and management of schistosomiasis of the spinal cord in 5 patients attending Shaab and Ibn Khuldoun Hospitals, Khartoum from 1997 to 2007. (who.int)
  • In this article, an overview of the most recent data about the role of interventional radiology in the management of these conditions will be presented, as well as the authors' experience on interventional management of schistosomiasis patients. (thieme-connect.com)
Eggs9
  • Schistosomiasis is due to immunologic reactions to Schistosoma eggs trapped in tissues. (medscape.com)
  • Herein, we show that i.p. injection of OVA + Al(OH) 3 minutes before i.v. injection of Schistosoma mansoni eggs into OVA tolerant mice blocked the increase of pulmonary granulomas. (hindawi.com)
  • Granulomatous inflammation triggered by S. mansoni eggs and the subsequent fibrosis has been considered a Th2-cytokine-driven inflammation [ 20 ]. (hindawi.com)
  • Schistosoma mansoni eggs injected into the tail vein of mice are transported into the lung tissue via the pulmonary arteries where they become trapped within the lung parenchyma [ 22 , 23 ]. (hindawi.com)
  • Patients not treated then enter the chronic form of the disease where the immune response to the eggs is not as severe. (appliedradiology.com)
  • Schistosoma mansoni eggs are large (114 to 180 µm long by 45-70 µm wide) and have a characteristic shape, with a prominent lateral spine near the posterior end. (farinelliandthekingbroadway.com)
  • criteria for inclusion in this study were two pre-treatment s. mansoni egg counts with a mean of greater than 100 eggs g-1 faeces and an enlarged spleen. (liverpool.ac.uk)
  • Schistosomiasis remains to be the most common fi brotic disease resulting from infl ammation and deposition of scar tissue around trapped parasitic eggs in the liver. (cu.edu.eg)
  • Kato-Katz and formol-ether concentration techniques were used to detect S. mansoni eggs in stool samples. (researchsquare.com)
Tropical and subtropical2
  • Schistosomiasis is a tropical and subtropical disease affecting those who live in areas with poor sanitation. (appliedradiology.com)
  • Schistosomiasis is most prevalent in tropical and subtropical areas, especially in poor communities without access to safe drinking water and adequate sanitation. (who.int)
Miracidia1
  • A total of 2,356 S. mansoni miracidia were directly isolated from fecal specimens of 104 hosts (i.e. 60 human hosts and 44 non-human primates). (ifremer.fr)
Mekongi2
  • Active schistosomiasis mekongi in Lao PDR and Cambodia might thus have been considerably underestimated previously. (biomedcentral.com)
  • The World Health Organization (WHO) roadmap for elimination of neglected tropical diseases (NTDs) [ 6 ] and the Regional Action Plan for NTDs in the Western Pacific Region for 2012-2016 issued by WHO's Western Pacific Region Office (WPRO) [ 7 ] recommend targeting schistosomiasis mekongi for elimination. (biomedcentral.com)
Morbidity2
  • Schistosomiasis and strongyloidiasis cause substantial morbidity and mortality among hundreds of millions of infected persons worldwide. (qxmd.com)
  • Morbidity in schistosomiasis: an update. (thieme-connect.com)
Granuloma2
Clinical5
  • Clinical findings compatible with acute schistosomiasis were recorded for 75 (66.4%) patients and 1993-2005. (cdc.gov)
  • Moreover, because local inhab- toms suggestive of acute schistosomiasis, the evolution to itants of disease-endemic areas are exposed repeatedly, the chronic schistosomiasis (genital, urinary, or gastrointesti- clinical manifestations may differ between residents and nal), or the diagnosis of asymptomatic schistosomiasis visitors. (cdc.gov)
  • These molecules have a history of prior testing in clinical trials unrelated to schistosomiasis. (experiment.com)
  • Clinical studies on these new cases of acute schistosomiasis have been revealing intriguing manifestations related to the immunopathology of the disease. (rsbmt.org.br)
  • Nevertheless further studies on the mechanism of action of C. spinosa L. in chronic liver diseases may shed light on developing therapeutic methods in clinical practice. (cu.edu.eg)
Urinary1
Puerto Ricans1
  • S. mansoni is often seen in Puerto Ricans living in the United States. (lookformedical.com)
Liver7
  • In schistosomiasis mansoni, the chronic egg-induced granulomatous response in the liver and intestines may eventually cause extensive tissue scarring and development of portal hypertension [ 16 ]. (hindawi.com)
  • This can lead to chronic conditions such as kidney failure, liver failure, and bladder cancer. (experiment.com)
  • Nonetheless, the extent to which selectins regulate the movement of leucocytes to visceral organs and the contribution of selectins towards the regulation of chronic sort two cytokine dependent liver disease remain fairly unclear. (bet-bromodomain.com)
  • Group-IV: 25 individuals with chronic HCV and liver cirrhosis (14males and 11females). (bet-bromodomain.com)
  • Schistosomiasis of the liver. (thieme-connect.com)
  • 9 Monzawa S, Uchiyama G, Ohtomo K, Araki T. Schistosomiasis japonica of the liver: contrast-enhanced CT findings in 113 patients. (thieme-connect.com)
  • This causes the chronic and more severe aspects of the disease such as organ damage, bladder cancer, liver fibrosis, and genital lesions. (infontd.org)
Asymptomatic1
  • Before August 2003, serologic tests were most- tosomiasis, chronic schistosomiasis had developed in 23 ly referred to CDC for fast-ELISA screening with (20.4%), and 48 (42.5%) were asymptomatic. (cdc.gov)
Snails3
  • In 2003, a S mansoni-S rodhaini hybrid was found in snails, the intermediate host, in Kenya. (medscape.com)
  • Schistosomiasis is caused by parasitic worms that live in certain types of freshwater snails. (world.edu)
  • Schistosomiasis is a parasitic disease spread by fresh water snails. (bcm.edu)
Trematode1
Populations2
  • Genetic diversity and population structure studies of S. mansoni have provided insights into the variation of natural populations. (ifremer.fr)
  • This latest study tested desiccated tissue samples from two Nubian populations for S. mansoni. (world.edu)
Parasitic worms2
  • Schistosomiasis is a disease caused by parasitic worms, transmitted through contact with contaminated freshwater. (who.int)
  • Schistosomiasis is a disease caused by small, blood-dwelling parasitic worms, also known as blood fluke. (infontd.org)
Kato-Katz1
  • Kato Katz thick smears and circulating cathodic antigen tests were performed for S. mansoni screening, whereas thick and thin blood smear techniques were performed for P. falciparum screening. (scirp.org)
Endemicity2
Hepatosplenic1
  • 3. Evidence of long-term hepatosplenic involvement by schistosomiasis, via compatible ultrasound findings (peri-portal fibrosis or enlarged left lobe) All patients will necessarily already be receiving at least one specific treatment for PAH, either with phosphodiesterase V inhibitor or with an endothelin receptor antagonist, with a stable dose for at least 12 weeks before inclusion in the study. (who.int)
Transmission dynamics2
  • Over time transmission dynamics of schistosomiasis have changed. (medscape.com)
  • With the World Health Organization (WHO) identifying some vector borne diseases (VBDs) as potentially eliminable / eradicable (e.g., onchocerciasis, lymphatic filariasis, schistosomiasis), it is timely to evaluate whether current transmission dynamics and control models for such diseases will usefully guide intervention programmes towards their projected endpoints. (imperial.ac.uk)
Fibrosis2
  • Granulomatous inflammation is involved in a number of diseases, and chronic granulomatous inflammation can cause damage and fibrosis to surrounding tissue [ 14 , 15 ]. (hindawi.com)
  • About 4.4 million people infected with S. mansoni suffer from bloody diarrhea, while 8.5 million people have hepatomegaly associated with periportal fibrosis, portal hypertension and hematemesis (2,3). (researchsquare.com)
Severe4
  • Schistosomiasis is a chronic severe illness with estimates from the World Health Organization (WHO) showing that at least 290.8 million people required preventive treatment in 2018, in which more than 97.2 million people were reported to have been treated [ 1 ]. (hindawi.com)
  • Parenteral injection of tolerated proteins into orally tolerant mice inhibits the initiation of immunological responses to unrelated proteins and blocks severe chronic inflammatory reactions of immunological origin, such as autoimmune reactions. (hindawi.com)
  • Schistosomiasis is a severe parasitic infestation with debilitating complications and is the third most devastating tropical disease in the world. (biomedcentral.com)
  • Schistosomiasis is a debilitating disease that causes severe pain and discomfort which can prevent those infected from being able to perform the basics tasks needed to keep their families alive. (experiment.com)
Disease7
  • Schistosomiasis is a parasitic disease that affects millions of people in 78 countries globally. (hindawi.com)
  • Children under the age of 14, who have the chronic disease may suffer from anemia and malnutrition that contribute to lost days at school and pervasive learning disabilities. (hindawi.com)
  • See also the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) information on schistosomiasis. (merckmanuals.com)
  • Mummies from along the Nile are revealing how age-old irrigation techniques may have boosted the plague of schistosomiasis, a water-borne parasitic disease that infects an estimated 200 million people today. (world.edu)
  • Advanced schistosomiasis is an infectious disease, endemic in some regions, with long-term implications for patient care. (thieme-connect.com)
  • Schistosomiasis is a neglected tropical disease affecting communities surrounded by water bodies where fishing activities take place or people go to swim, wash and cultivate crops. (itb.ac.id)
  • Instead, the burden of disease is related less to mortality than to the chronic and insidious effects on the hosts' health and nutritional status [ 16 17 ]. (ispub.com)
Schistosomes1
  • 13 Richter J. Evolution of schistosomiasis-induced pathology after therapy and interruption of exposure to schistosomes: a review of ultrasonographic studies. (thieme-connect.com)
Experimental2
Diseases1
  • We hope that understanding the impact of schistosomiasis in the past may help in finding ways to control what is one of the most prevalent parasitic diseases in the world today,\" Campbell Hibbs says. (world.edu)
Manifestations1
  • Le présent article décrit les manifestations cliniques, le diagnostic et la prise en charge de la schistosomiase médullaire chez cinq patients admis dans les hôpitaux Shaab et Ibn Khaldoun de Khartoum entre 1997 et 2007. (who.int)
Treatment3
  • The high seroprevalence of schistosomiasis and strongyloidiasis among Sudanese Lost Boys and Girls and Somali Bantu refugees supports presumptive treatment for these refugees. (qxmd.com)
  • Early treatment is essential, as chronic bladder inflammation can lead to squamous metaplasia and squamous cell carcinoma. (appliedradiology.com)
  • These compounds have known safety profiles and will serve as a promising starting point for the development of new treatment options against schistosomiasis. (experiment.com)