• Sanofi and Regeneron ) as an add-on maintenance treatment in adult patients with inadequately controlled chronic rhinosinusitis with nasal polyposis (CRSwNP). (empr.com)
  • Data regarding the imbalance in follicular helper T (Tfh) and follicular regulatory T (Tfr) cell responses in patients having chronic rhinosinusitis with nasal polyps (CRSwNP) is so far limited. (tinnitusjournal.com)
  • Background: Polyps from patients with chronic rhinosinusitis with nasal polyps (CRSwNP) contain increased levels of autoreactive antibodies, B cells and fibrin deposition. (northwestern.edu)
  • Chronic rhinosinusitis (CRS) with nasal polyposis (CRSwNP) is a chronic inflammatory condition with significant patient morbidity and associated healthcare costs. (qxmd.com)
  • Patients with CRSwNP have higher disease burden and healthcare resource utilization than those with CRS without nasal polyposis. (qxmd.com)
  • CRSwNP is a chronic condition with high recurrence rates making it a challenge to manage over time. (qxmd.com)
  • Fifth Sense is pleased to be partnering with the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) to support the first ever global awareness day for Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) on 20th April. (fifthsense.org.uk)
  • Chronic rhinosinusitis with nasal polyps (CRSwNP) is a principal clinical entity confirmed by the existence of chronic sinonasal inflammation and is characterized by anterior or posterior rhinorrhea, nasal con-gestion, hyposmia and/or facial pressure or facial pain. (elsevierpure.com)
  • Chronic rhinosinusitis with nasal polyps (CRSwNP) is a multifactorial disease resulting from inflammation of the nasal cavity and paranasal sinuses. (j-rhinology.org)
  • Currently, this disease classified as subgroups of patients based on nasal endoscopic findings, either accompanied by nasal polyps (CRSwNP) or without nasal polyps (CRSsNP) [ 1 ]. (j-rhinology.org)
  • CRSwNP is a chronic disease of the upper airway that obstructs the sinuses and nasal passages and Dupixent, as an add-on therapy to intranasal corticosteroid, can help to control persistent, often debilitating symptoms such as nasal congestion, difficulty breathing and loss of smell that can severely impact quality of life. (galencentre.org)
  • Chronic rhinosinusitis (CRS) includes two main phenotypes: without nasal polyps (CRSsNP) and with nasal polyps (CRSwNP). (uniba.it)
  • Several controlled trials showed that dupilumab is effective and safe in patients with atopic dermatitis (AD), severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP), thus resulting in approval by regulatory agencies. (unisr.it)
  • Dupilumab is indicated for the treatment of moderate-to-severe atopic dermatitis, moderate-to-severe asthma, and for the treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP). (wikipedia.org)
  • They are invariably associated with chronic rhinosinusitis with the presentation correctly labelled as chronic rhinosinusitis with nasal polyps (CRSwNP). (bmj.com)
  • Transcriptional analysis of nasal polyps fibroblasts reveals a new source of pro-inflammatory signaling in CRSwNP. (amedeo.com)
  • Fig. (1) Evaluation of radiologic signs of nasal polyposis from sinus Computed Tomography (CT) scans. (benthamopen.com)
  • Knowledge of nasal polyposis extends to medical antiquity. (medscape.com)
  • Only 0.5% of individuals with atopic symptoms manifest nasal polyposis, and most patients with diffuse nasal polyposis do not demonstrate an immunoglobulin E (IgE)-mediated type 1 hypersensitivity reaction. (medscape.com)
  • Nasal polyposis in association with cystic fibrosis, sinobronchial syndrome, aspirin sensitivity, and Samter triad (asthma, aspirin allergy, nasal polyposis) indicates manifestation of nasal mucosal damage by many different possible disease processes. (medscape.com)
  • Results: In total, 82 patients with nasal polyposis were identified. (unisr.it)
  • Nasal polyposis is an inflammatory condition of unknown etiology. (medscape.com)
  • Nasal polyposis can impair a person's quality of life more than perennial allergic rhinitis. (medscape.com)
  • Coronal sinus computed tomography (CT) scanning is the imaging study of choice in the evaluation of patients with nasal polyposis. (medscape.com)
  • Patients with massive nasal polyposis typically present with increasing nasal congestion, hyposmia to anosmia, changes in sense of taste, and persistent postnasal drainage. (medscape.com)
  • On occasion, a patient with completely obstructing nasal polyposis presents with symptoms of obstructive sleep apnea. (medscape.com)
  • Nasal polyposis results from chronic inflammation of the nasal and sinus mucous membranes. (medscape.com)
  • Nasal obstruction due to polyposis can also lead to hyposmia or even anosmia. (medscape.com)
  • The pathogenesis of nasal polyposis is unknown. (medscape.com)
  • (3, 13) Another study in 2015 has shown that patients suffering from chronic rhinosinusitis with nasal polyps may also have a history of asthma and allergies. (epainassist.com)
  • Nasal polyps are also associated with asthma, aspirin sensitivity, cystic fibrosis and allergic fungal rhinosinusitis (AFS). (johnshopkins.edu)
  • The trial was conducted to examine the impact of dupilumab on blood and nasal type 2 inflammatory biomarkers in patients with chronic rhinosinusitis with nasal polyps, with and without comorbid asthma. (medpagetoday.com)
  • Influence of omalizumab on treatment costs for chronic rhinosinusitis with nasal polyps and asthma: an insurance claims analysis. (bvsalud.org)
  • Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. (wikipedia.org)
  • Endoscopic sinus surgery (ESS) has no significant impact on asthma symptoms for patients with chronic rhinosinusitis up to a year after the procedure, a study of 64 patients shows. (medscape.com)
  • Although ESS is effective in relieving chronic rhinosinusitis, whether it leads to improvement of asthma severity for patients with both conditions remains unclear, said Anyull Dayanna Bohorquez Caballero in a presentation at the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) 2023 Annual Meeting. (medscape.com)
  • Under the leadership of senior author Angela Donaldson, MD, Bohorquez Caballero and colleagues at the Mayo Clinic in Jacksonville analyzed data from 185 adults with both asthma and chronic rhinosinusitis who underwent ESS at the Mayo Clinic in Florida between 2013 and 2023. (medscape.com)
  • In addition, "Our study also identified crucial opportunities to reinforce interdisciplinary follow-up after ESS," she noted, and it provides a comprehensive depiction of the outcomes experienced by patients with chronic rhinosinusitis and asthma who undergo ESS. (medscape.com)
  • The current study is important because of the frequency of comorbid asthma among patients with chronic rhinosinusitis, said Megan Durr, MD, of the University of California, San Francisco, in an interview. (medscape.com)
  • Physiological consequences associated with eosinophil-driven remodeling include impaired lung function and reduced bronchodilator reversibility in asthma, and obstructed airflow in chronic rhinosinusitis with nasal polyps. (lu.se)
  • This review provides an overview of tissue remodeling in both health and airway disease with a particular focus on eosinophilic asthma and chronic rhinosinusitis with nasal polyps, as well as the role of eosinophils in these processes and the implications for therapeutic interventions. (lu.se)
  • Common respiratory disorders like chronic rhinosinusitis and asthma have recently been linked to elevated levels of IL-25, but the cellular source of it in the respiratory system was unknown until now. (sciencedaily.com)
  • Furthermore, treating these cells in a petri dish with the inflammatory molecule Interleukin-13 (IL-13), which has been implicated in driving nasal polyp formation and asthma, stimulated expansion of the SCCs and increased production of IL-25. (sciencedaily.com)
  • We can measure levels of IL-25 in the mucus, so it's possible this can be an indicator of who will develop conditions like polyps or asthma," said the study's lead author Michael Kohanski, MD, PhD, a Rhinology Fellow at Penn. (sciencedaily.com)
  • Chronic rhinosinusitis with nasal polyps is strongly associated with asthma. (bmj.com)
  • Chronic bronchitis (49.1%) and asthma (36.1%) were the most common clinical diagnoses. (who.int)
  • Sinusitis is another term used for rhinosinusitis, or inflammation of the nasal passageways. (healthline.com)
  • Sinusitis is nothing but rhinosinusitis, which is inflammation of the nasal passage. (epainassist.com)
  • Certain allergy nasal sprays - including fluticasone (Flonase, Xhance) - may help reduce inflammation and improve symptoms such as congestion and runny nose. (healthline.com)
  • Results showed that compared with placebo, patients treated with Dupixent had a statistically significant reduction in nasal polyp size (33% and 27% reduction with Dupixent vs 7% and 4% increase with placebo in SINUS-24 and SINUS-52, respectively) and nasal congestion (57% and 51% improvement in nasal congestion/obstruction severity vs 19% and 15% improvement with placebo in SINUS-24 and SINUS-52, respectively). (empr.com)
  • tiredness from lack of sleep due to nasal congestion and tenderness surrounding the cheeks, forehead and nose. (epainassist.com)
  • Patients with nasal polyps often present with complaints including nasal obstruction, congestion, rhinorrhea or altered sense of smell. (johnshopkins.edu)
  • Chronic rhinosinusitis (CRS) is recognized when the four most common symptoms such as cough, rhinorrhea, nasal congestion and post-nasal drip with a slightly higher predominance of chronic cough are present for over 12 weeks and influence the quality of life. (edu.pl)
  • Corticosteroid pills or liquid may also shrink polyps, and can reduce swelling and nasal congestion. (medlineplus.gov)
  • they include nasal congestion and blockage, rhinorrhea, posterior nasal drip, and decreased sense of smell. (bmj.com)
  • Some treatments can help shrink nasal polyps to prevent further obstruction of your nasal cavity. (healthline.com)
  • It is associated with two or more symptoms of either nasal obstruction or nasal discharge (anterior/posterior nasal drip), facial pain/pressure, and/or reduction/loss of smell. (j-rhinology.org)
  • Patients usually present with nasal obstruction, persistent nasal discharge (rhinorrhea), sinus infection, and loss of the sense of smell (anosmia) of prolonged duration. (medscape.com)
  • Mepolizumab added to standard-of-care treatments also met both study primary endpoints, showing statistically significant improvements in size of nasal polys and nasal obstruction versus placebo, she reported at the virtual European Respiratory Society (ERS) International Congress . (medpagetoday.com)
  • All patients recruited for the trial were non-smokers or former smokers, were biologic- and immunosuppressant treatment-naive, had nasal obstruction visual analog scale (VAS) scores of 5 or greater, and were judged to be in need of repeat polyp surgery. (medpagetoday.com)
  • Changes in total endoscopic nasal polyp score at week 52 and nasal obstruction VAS score at weeks 49 to 52 were the study's primary endpoints. (medpagetoday.com)
  • Olfaction and nasal obstruction are the most important considerations in terms of symptoms. (medscape.com)
  • Patients with solitary polyps frequently present with only symptoms of nasal obstruction, which may change with a shift in position. (medscape.com)
  • Obstruction of the sinus ostia frequently occurs and may lead to acute or chronic sinus conditions. (medscape.com)
  • Large polyps can block your sinuses or nasal airway. (medlineplus.gov)
  • However, nasal sprays, antihistamines, and allergy shots may help prevent polyps that block your airway. (medlineplus.gov)
  • The association between allergic rhinitis and airway dysfunction and nasal endothelial damage and oxidative stress. (amedeo.com)
  • Bronchiectasis is best considered the common end-point of various disorders that cause chronic airway inflammation. (msdmanuals.com)
  • Chronic rhinosinusitis is a long term chronic irritation of the nasal cavity and sinuses with inflammation lasting for a minimum of 12 weeks. (epainassist.com)
  • Recently, the presence of local allergy in the nasal cavity was found in a number of patients diagnosed previously with non-allergic rhinitis [ 6 - 8 ]. (j-rhinology.org)
  • They often grow where the sinuses open into the nasal cavity. (medlineplus.gov)
  • Polyps look like a grayish grape-shaped growth in the nasal cavity. (medlineplus.gov)
  • Nasal polyps are the most common tumors of the nasal cavity. (medscape.com)
  • therefore, conditions leading to chronic inflammation in the nasal cavity can lead to nasal polyps. (medscape.com)
  • During descent, the air pressure on the ostia may increase from the nasal to the sinus side, while during ascent, the sinus cavity may expand against the ostia. (medscape.com)
  • In March of 2023, Sanofi announced the results of a Phase 3 trial examining the efficacy of dupilumab in the treatment of chronic obstructive pulmonary disease (COPD). (wikipedia.org)
  • EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023. (amedeo.com)
  • Objective: To compare APA levels (anti-cardiolipin, anti-phosphatidylethanolamine (anti-PE), and anti-β 2 -glycoprotein (anti-B2GP)) in nasal polyp (NP) tissue with tissue from control and CRS without nasal polyp (CRSsNP) patients, we tested whether NP antibodies affect coagulation, and correlate APAs with anti-dsDNA IgG and markers of coagulation. (northwestern.edu)
  • This distinguishes the presentation from chronic rhinosinusitis without nasal polyps (CRSsNP), which is covered in a separate topic. (bmj.com)
  • NICE is unable to make a recommendation on omalizumab (Xolair) for treating chronic rhinosinusitis with nasal polyps in adults because Novartis Pharmaceuticals did not provide an evidence submission. (nice.org.uk)
  • Dupilumab, Omalizumab, and Mepolizumab are types of approved biologic monoclonal antibodies that block the inflammatory response and treat moderate to severe CRS with nasal polyps, and give the patient complete improvement. (entspecialistdubai.com)
  • Novartis' anti-IgE drug omalizumab (Xolair) won European approval in August as add-on therapy for adults with poorly controlled severe chronic rhinosinusitis and nasal polyps. (medpagetoday.com)
  • Current standard-of-care therapies for chronic rhinosinusitis and nasal polyps include intranasal corticosteroids, saline irrigation, short-term oral steroids, and surgery. (medpagetoday.com)
  • Oral corticosteroids are the most effective short-term medical treatment for nasal polyps. (medscape.com)
  • Patients whose polyps respond to oral corticosteroids may be re-treated safely 3-4 times a year, especially if they are not candidates for surgery. (medscape.com)
  • Nasal polyps are benign growths of soft tissue within the nose. (epainassist.com)
  • The differential diagnosis ranges from benign masses such as schneiderian papilloma, antrochoanal polyp, angiofibroma and encephalocele to malignant neoplasms such as squamous cell carcinoma (SCC), esthesioneuroblastoma, nasal lymphoma and rhabdomyosarcoma. (johnshopkins.edu)
  • Nasal polyps (NP) are benign swellings of the mucosal lining of the paranasal sinuses. (bmj.com)
  • Pediatric rhinosinusitis in children is defined as a presence of two or more symptoms with one of them either being nasal blockage or nasal discharge and headache/facial pain or cough. (edu.pl)
  • Chronic inflammation causes a reactive hyperplasia of the intranasal mucosal membrane, which results in the formation of polyps. (medscape.com)
  • In case of any weird or chronic sinus symptoms, it is important to seek medical attention for the right diagnosis and treatment. (epainassist.com)
  • These lesions may have a similar appearance as nasal polyps and particular attention to an alternative diagnosis for nasal polyps should be entertained if the mass is unilateral or congenital in nature. (johnshopkins.edu)
  • Here, we review the disease etiology of nasal polyps and describe the approach to the patient with nasal polyps with emphasis on differential diagnosis and workup. (johnshopkins.edu)
  • London, NR & Reh, DD 2016, ' Differential Diagnosis of Chronic Rhinosinusitis with Nasal Polyps ', Advances in oto-rhino-laryngology , vol. 79, pp. 1-12. (johnshopkins.edu)
  • In a study of 10,336 US adults, Palmer et al found that 11.5% of these individuals reported symptoms of chronic rhinosinusitis, with about 10% of this subgroup indicating that they had received a previous diagnosis of nasal polyps. (medscape.com)
  • Nasal masses that do not have the classic appearance of nasal polyps (translucent to gray, fleshy and pedunculated) or that do not respond to conservative medical treatment should be biopsied for confirmatory diagnosis. (medscape.com)
  • These growths can also worsen rhinosinusitis symptoms by blocking normal mucus flow. (healthline.com)
  • Nasal polyps refer to growths that line the nasal passageways. (healthline.com)
  • Nasal polyps are non-cancerous growths, which develop in the nasal passage and in some cases can also grow into the sinuses. (epainassist.com)
  • Nasal polyps are non-cancerous soft growths varying in size and number in the lining of the nasal canal or sinuses. (entspecialistdubai.com)
  • Nasal polyps are soft, sac-like growths on the lining of the nose or sinuses. (medlineplus.gov)
  • Chronic rhinosinusitis (CRS) is defined as an inflammatory condition involving the paranasal sinuses, which persists for 12 weeks or longer. (j-rhinology.org)
  • Hopkins noted that chronic rhinosinusitis with nasal polyps is an inflammatory condition that affects approximately 4% of adults, and has a significant impact on quality of life. (medpagetoday.com)
  • Because lupus is a chronic, complex and potentially isolating disease, we have a shared ambition with lupus advocacy organizations and patient groups to address unmet needs of people with this immuno-inflammatory condition. (gsk.com)
  • Treatment for CRwNP is focused on decreasing inflammation in your sinuses and nasal passages to reduce your symptoms. (healthline.com)
  • Your doctor may prescribe these periodically to treat severe inflammation in your sinuses and nasal passages. (healthline.com)
  • Doctors also recommend regularly using a saline nasal spray to rinse your nasal passages. (healthline.com)
  • If polyps block nasal passages, a sinus infection can develop. (medlineplus.gov)
  • They help clear blocked nasal passages and runny nose. (medlineplus.gov)
  • The tube is inserted into your nasal passages and your surgeon removes the polyps. (medlineplus.gov)
  • The exact etiology of polyp formation is unknown. (medscape.com)
  • Evidences for local allergy are supported by clinical symptoms, local production of allergen-specific immunoglobulin E (sIgE), a type 2 helper T cell inflammatory pattern in nasal secretions during natural exposure to aeroallergens, and a positive response to nasal allergen provocation with local nasal production of slgE to aeroallergens, tryptase, and eosinophil cationic protein (ECP) [ 9 ]. (j-rhinology.org)
  • Allergy medicines can help prevent polyps from growing back. (medlineplus.gov)
  • Nasal polyps are associated more strongly with conditions and diseases that do not have an allergy component than with those that do. (medscape.com)
  • In June 2019, the IL-4 inhibitor dupilumab (Dupixent) became the first FDA-approved treatment for poorly controlled chronic rhinosinusitis with nasal polyps. (medpagetoday.com)
  • The study found that consistent with the drug's mechanism of action, dupilumab reduced both blood and nasal secretion biomarkers of type 2 inflammation in these patients. (medpagetoday.com)
  • Dupilumab for chronic rhinosinusitis with nasal polyps: real-life retrospective 12-month effectiveness data. (amedeo.com)
  • This article will explore nasal polyps treatment without surgery, non-surgical sinus treatments, and medications for nasal polyps. (entspecialistdubai.com)
  • In patients with chronic rhinosinusitis with nasal polyps, add-on mepolizumab (Nucala) reduced both polyp size and the need for surgery in the SYNAPSE study, a researcher reported. (medpagetoday.com)
  • In the 52-week, phase III, multicenter trial, treatment with the IL-5 inhibitor biologic was associated with a 57% reduction in the need for surgery versus placebo in patients with a history of one or more surgeries to reduce polyps, according to Claire Hopkins, MD, of King's College London. (medpagetoday.com)
  • SYNAPSE was conducted to examine the efficacy and safety of 4-weekly injections of 100 mg of mepolizumab in the treatment of adults with chronic rhinosinusitis and nasal polyps considered to be candidates for repeat surgery. (medpagetoday.com)
  • In an earlier trial involving a 750-mg intravenous dosage of mepolizumab given every 4 weeks for a total of six doses, treatment was associated with reductions in nasal polyp size, improved symptoms, and reduced need for nasal surgery. (medpagetoday.com)
  • Secondary endpoints included time to nasal polyp surgery during the study, overall VAS symptom score, Sinonasal Outcome Test-22 score, systemic corticosteroid (SCS) use, composite and loss of smell VAS scores. (medpagetoday.com)
  • Mepolizumab reduced nasal polyp surgery by 57% (hazard ratio 0.43, 95% CI 0.25-0.76, P =0.003), improved SNOT-22, VAS (overall, composite, loss of smell), and systemic corticosteroid use. (medpagetoday.com)
  • If medicines don't work, or you have very large polyps, you may need surgery to remove them. (medlineplus.gov)
  • Endoscopic sinus surgery is often used to treat polyps. (medlineplus.gov)
  • Sometimes polyps come back, even after surgery. (medlineplus.gov)
  • Removing polyps with surgery often makes it easier to breathe through your nose. (medlineplus.gov)
  • Tissue eosinophilia and computed tomography features in paediatric chronic rhinosinusitis with nasal polyps requiring revision surgery. (amedeo.com)
  • The mucus Fluid can get trapped in the sinus cavities, resulting in acute infection and the development of chronic rhinosinusitis type that grows nasal polyps. (entspecialistdubai.com)
  • NP antibodies have in vitro anti-coagulant activity similar to those observed in anti-phospholipid syndrome, suggesting that they may have pro-coagulant effects in polyp tissue. (northwestern.edu)
  • The majority of nasal polyps are bilateral and characterized by tissue edema and eosinophil infiltration. (johnshopkins.edu)
  • Eosinophilic esophagitis is a chronic inflammatory disorder in which eosinophils, a type of white blood cell, are found in the tissue of the esophagus. (wikipedia.org)
  • Investigators aim to compare the percentage of ILC2 and tuft cells present in nasal tissue and secretions between those who present with nasal polyp. (ucsfhealth.org)
  • However, when Penn researchers looked at human nasal polyps, the number of SCCs lining the polyp tissue was massively increased. (sciencedaily.com)
  • Polyp tissue comprises a mixture of loose connective tissue, edema, inflammatory cells (mostly eosinophils), glandular cells, and capillaries. (bmj.com)
  • Diseases impacting sinuses and nasal function include CF, primary ciliary dyskinesia (PCD) and a variety of normal immune deficiencies, including the still-developing immature immunity of healthy young children. (edu.pl)
  • Anti-phospholipid antibodies (APA) are autoantibodies known to cause thrombosis but have not been implicated in chronic rhinosinusitis (CRS). (northwestern.edu)
  • Newer treatments such as injection therapy with anti-IGE antibodies may help prevent polyps from coming back. (medlineplus.gov)
  • Systemic lupus erythematosus (SLE), or lupus, is a chronic disease that involves the immune system and can damage any part of the body.iv Normally, the immune system works to fight off invaders, such as viruses and bacteria, by making antibodies. (gsk.com)
  • Today, the standard surgical therapy is endoscopically guided removal of diseased tissues with preservation of maximal amount of normal nasal mucosa. (medscape.com)
  • Ongoing work explores how epithelial cells of the sinuses and olfactory mucosa participate in the immune response and contribute to chronic inflammation. (hopkinsmedicine.org)
  • The UCSF Advanced COPD Clinic cares for patients with severe chronic obstructive pulmonary disease and emphysema. (ucsfhealth.org)
  • Biologicals in severe chronic rhinosinusitis with nasal polyps: translation to clinical practice while waiting for head-to-head studies. (amedeo.com)
  • Biologic treatment for severe chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis. (amedeo.com)
  • In addition, polyps can sometimes arise from inflammation caused by malignant or premalignant nasal lesions. (medscape.com)
  • It is important to distinguish nasal polyps from neoplastic lesions, particularly if symptoms are unilateral. (bmj.com)
  • They may also recommend a full medical workup to look for other health conditions that often occur with nasal polyps. (healthline.com)
  • Efficacy and safety of switching between biologics in chronic rhinosinusitis with nasal polyps or N-ERD. (amedeo.com)
  • Rheumatoid Arthritis (RA) Rheumatoid arthritis is a chronic systemic autoimmune disease that primarily involves the joints. (msdmanuals.com)
  • Sjögren Syndrome Sjögren syndrome is a relatively common chronic, autoimmune, systemic, inflammatory disorder of unknown cause. (msdmanuals.com)
  • Your doctor may diagnose you with chronic rhinosinusitis if your symptoms last for at least 12 weeks even with treatment. (healthline.com)
  • Nasal polyps treatment goal is often to manage symptoms and reduce their size rather than achieving a permanent cure. (entspecialistdubai.com)
  • The presentation of the SYNAPSE study findings was one of several discussions addressing the growing role of biologic therapies in the treatment of nasal polyps at ERS. (medpagetoday.com)
  • Type 2 inflammation plays a very central role in the pathophysiology of nasal polyps and treatment of type 2 inflammation has shown promise. (medpagetoday.com)
  • In an ERS session sponsored by drugmaker Novartis, Philippe Gevaert, MD, PhD, of Ghent University in Belgium, presented an overview of the data evaluating anti-IgE biologic therapies as add-on therapies for the treatment of nasal polyps. (medpagetoday.com)
  • Surgical intervention for rhinosinusitis is usually considered for patients with CRS who have failed maximal pharmacological treatment. (edu.pl)
  • Chronic rhinosinusitis: outcomes of medical and surgical treatment. (medlineplus.gov)
  • Treatment modalities are depending on the clinical phenotypes of NH and they will embrace for each patient: the avoidance of culprit NSAID, the finding of well-tolerated NSAID and in certain cases, desensitization procedures when the NSAID treatment was absolutely needed as well as the control of associated diseases such as spontaneous chronic urticarial or allergic respiratory diseases. (intechopen.com)
  • Blood eosinophils to direct oral corticosteroid treatment for patients with nasal polyps aeuro" an open label, non-inferiority, randomized control trial. (amedeo.com)