Chronic or persistent manifestations. Medical search. Frequent questions

Trench fever, also known as five-day fever or quintan fever, is the initial manifestation of B. quintana infection. (wikipedia.org)
Clinical manifestations range from asymptomatic infection to severe illness. (wikipedia.org)
Chronic infection manifestations include attacks of fever and aching in some cases and persistent bacteremia in soldiers and homeless people. (wikipedia.org)
CHB infection is associated with several extrahepatic manifestations, some of which are systemic (e.g., serum sickness and polyarteritis nodosa) and some are localized, such as dermatologic manifestations (e.g., urticaria, leukocytoclastic vasculitis, and essential mixed cryoglobulinemia) [ 5 , 6 ]. (hindawi.com)
Patients who have recovered from coronavirus disease 2019 (COVID-19) infection may experience chronic fatigue when exercising, despite no obvious heart or lung abnormalities. (mdpi.com)
The rationale for a proposed randomised controlled trial (RCT) of suppressive antiviral treatment to reduce chronic eye disease and postherpetic neuralgia (PHN) includes evidence that zoster is followed by chronic active VZV infection and similarities between HZO and herpes simplex virus (HSV) eye infection, where this treatment is effective and is the standard of care. (bmj.com)
Experts regard HIV disease as beginning at the time of primary (acute) HIV infection and progressing through numerous stages of chronic infection. (medscape.com)
Chronic HIV infection begins after antibodies to the virus have fully developed and the initial immune response is complete. (medscape.com)
Some individuals develop symptoms or organ dysfunction during chronic infection due to direct effects of the virus rather than a defect in cell-mediated immunity. (medscape.com)
Acquired immunodeficiency syndrome (AIDS) is the condition that results from long-term (chronic) HIV infection and is defined by an absolute CD4 cell count of less than 200 cells/µL and specific opportunistic infections or malignancies. (medscape.com)
In many infected individuals, an opportunistic disease is the first manifestation of HIV infection. (medscape.com)
Human T-lymphotropic virus type I (HTLV-I) causes chronic infection for which there is no cure or neutralising vaccine. (ebi.ac.uk)
A key issue in current HTLV-I research is to better understand the dynamic interaction between persistent infection by HTLV-I and virus-specific host immunity. (ebi.ac.uk)
Examining the particular roles of viral expression and host immunity during the chronic phase of HTLV-I infection offers important insights regarding the evolution of viral persistence and proposes a hypothesis for pathogenesis. (ebi.ac.uk)
The present invention provides a simple and robust human liver cell-based system in which persistent hepatitis C infection, persistent hepatitis B infection or ethanol exposure induces a clinical Prognostic Liver Signature (PLS) high-risk gene signature. (sumobrain.com)
FGS is the chronic manifestation of a persistent infection with Schistosoma haematobium. (bvsalud.org)
Although early recognition and treatment lead to resolution of illness for many patients, there are many who live with persistent, debilitating symptoms, and persistent infection - which ILADS terms chronic Lyme disease. (txlymealliance.org)
What is the risk of B-cell non-Hodgkin's lymphoma in patients with chronic HCV infection? (nejm.org)
Unequivocal data support a causal relationship between chronic hepatitis C virus (HCV) infection and certain disorders, including cryoglobulinemic vasculitis, lymphoma, cardiovascular diseases, insulin resistance, and type 2 diabetes. (nejm.org)
Q: What is the risk of B-NHL in patients who have chronic HCV infection with cryoglobulinemia? (nejm.org)
The overall risk that B-NHL will develop in patients who have chronic HCV infection with cryoglobulinemia is about 35 times as high as the risk in the general population, or 12 times as high if nonaggressive lymphomas are excluded. (nejm.org)
Hepatitis C virus (HCV) establishes a persistent infection and causes chronic hepatitis. (go.jp)
The development of this pathological condition is linked to the persistent infection of the virus. (go.jp)
Understanding the molecular mechanism of HCV replication will help elucidate the pathogenic mechanism and develop preventive measures that inhibit disease manifestation by blocking persistent infection. (go.jp)
In adults, ongoing HBV transmission occurs primarily among unvaccinated persons with behavioral risks for HBV transmission (e.g., heterosexuals with multiple sex partners, injection-drug users [IDUs], and men who have sex with men [MSM]) and among household contacts and sex partners of persons with chronic HBV infection. (cdc.gov)
Persistent infection arises due to inability of host cells to clear primary infections completely. (bvsalud.org)
When persistent infections are cleared so that infection symptoms are under control they are often referred to as chronic infections. (bvsalud.org)
Chronic hepatitis B virus (HBV) infection affects more than 350 million people worldwide, with 75% living in the Asia-Pacific region [ 2 ]. (biomedcentral.com)
Moreover, chronic HBV infection continues to be a major health problem because it leads to the development of liver cirrhosis and hepatocellular carcinoma and increases the risk of hepatic disease-related death. (biomedcentral.com)
ABSTRACT In this study, endoscopy patients with and without chronic liver disease (CLD) were examined and tested for Helicobacter pylori infection by detecting the presence of serum and salivary anti-H. pylori antibody. (who.int)

Often their first and only manifestations are symptoms of sleep disorders. (azlawhelp.org)
In the Patient-Reported Outcomes with LASIK (PROWL) studies, excellent visual acuity was routinely achieved, with few highly bothersome, persistent symptoms and very rare vision-threatening complications. (aafp.org)
Caution individuals with chronic pain syndromes (e.g., fibromyalgia, irritable bowel syndrome, migraine) or contact lens intolerance that patients with these conditions report more dry eye symptoms following LASIK. (aafp.org)
Dry eye symptoms are multifactorial, but some may be manifestations of corneal neuropathy. (aafp.org)
Chronic pancreatitis, a condition marked by persistent inflammation of the pancreas, brings with it a series of symptoms that can significantly alter an individual's life. (localquoter.net)
In delving into the ten most common symptoms, this article aims to arm individuals with the knowledge they need to navigate through the turbulent waters of chronic pancreatitis. (localquoter.net)
Its clinical expression is very variable: from acute and sporadic symptoms to chronic, from seasonal or appearing in relation to exercise, to a serious and persistent disease. (pap.es)
Chronic Fatigue Syndrome (CFS), previously known as Chronic Epstein-Barr Virus Syndrome, and also currently called Chronic Fatigue and Immune Dysfunction Syndrome, is a systemic disorder consisting of a complex of variable signs and symptoms which may vary in duration and severity. (theatlantasocialsecurityattorney.com)
CFS is characterized by the presence of persistent unexplained fatigue and by the chronicity of other symptoms. (theatlantasocialsecurityattorney.com)
LATENT INFECTIONS are infections in which manifestation of clinical symptoms appear later. (bvsalud.org)
Persistent depressive disorder symptoms usually last for at least 2 years and occur in episodes of several months with varying intensity. (easyhealthylive.com)
Symptoms of AS include those related to inflammatory back pain, peripheral enthesitis and arthritis, and constitutional and organ-specific extra-articular manifestations. (medscape.com)
Later manifestations include gastrointestinal symptoms: hepatomegaly/hepatosplenomegaly, esophageal outlet, pyloric, and/or urethral obstruction, persistent diarrhea - granulomatous colitis, perianal abscesses or rectal fistulous tracts. (lu.se)

In addition to recurrent acute arthritis, subcutaneous tophi and chronic painful arthritis, 1 it also has an impact on morbidity 2- , 4 and premature mortality. (bmj.com)
Periodontitis is a highly prevalent, chronic multifactorial infectious disease, induced by the dysbiotic biofilm that triggers a persistent systemic inflammation and recurrent bacteremia. (intechopen.com)
It is characterised by persistent or recurrent debilitating fatigue. (vardaan.net)
There are 4 clinically distinct stages of VKH syndrome: (1) prodromal, (2) acute uveitic, (3) convalescent, and (4) chronic recurrent. (aao.org)
The chronic recurrent stage is characterized by granulomatous choroiditis with damage to the choriocapillaris. (aao.org)
The patient is a 30 years-old woman that referred since the 21 months of age persistent fever, chronic polyarthritis, skin rash, and ocular manifestations including recurrent bilateral uveitis. (biomedcentral.com)
Early manifestations include chronic and recurrent pyogenic infections during first 2 years of life, lymphadenopathy, recurrent enlargement of lymph nodes of neck. (lu.se)

Chronic fatigue symptom complex of unknown aetiology has received considerable attention recently as well as in the past. (vardaan.net)
In addition, it is possible that episodes of major depression may occur before or during persistent depressive disorder, a symptom known as double depression. (easyhealthylive.com)
Inflammatory back pain is the most common symptom and the first manifestation in approximately 75% of patients. (medscape.com)
In Western countries, pain in the a symptom or a manifestation of a painful muscular neck is reported as a major cause of long-term sick disorder1. (bvsalud.org)

Asthma, a chronic respiratory disease, is notably characterized by reversible airway obstruction, persistent lung inflammation, and airway hyperresponsiveness (AHR). (cdc.gov)
Mild episodic asthma is mainly due to bronchial smooth muscle contraction whereas moderate to severe sustained asthma is largely due to chronic inflammation of the bronchi with the presence of white cells such as eosinophils , neutrophils and mononuclear cells that are part of an inflammatory response . (diagnose-me.com)
Chronic inflammation is associated with an increased number of leukocytes in the spleen, which are then redirected to the site of inflammation. (hindawi.com)
Herein, chronic inflammation was induced by intraperitoneal injection of pristane into mice. (hindawi.com)
These data provide insight into the development of chronic inflammation induced by noninfectious substances. (hindawi.com)
Noninfectious inflammation can be induced by persistent indigestible substances. (hindawi.com)
Pristane-induced chronic inflammation has been characterized by the continuous recruitment of leukocytes, including lymphocytes, neutrophils, and macrophages, to the peritoneal cavity and the spleen [ 6 - 8 ]. (hindawi.com)
However, children and adolescents with COVID-19 may have persistent inflammation, with isolated or concomitant lesions on various organs. (fapesp.br)
4) chronic tissue and organ damage characterized by thrombotic endothelialitis, endothelial inflammation, hyperactivated platelets, and fibrinaloid microclots. (cdc.gov)
Many acute and chronic lung disorders with variable degrees of pulmonary inflammation and fibrosis are collectively referred to as interstitial lung diseases (ILDs) or diffuse parenchymal lung diseases. (atsjournals.org)

Some infected persons who are otherwise asymptomatic develop persistent generalized lymphadenopathy (PGL) during this time. (medscape.com)

In addition to well-recognized contraindications (e.g., unstable refraction, pregnancy and lactation, chronic eye disease, systemic illness, corneal abnormalities), there are other conditions that warrant caution (e.g., excessively dry eyes, contact lens intolerance, chronic pain syndromes). (aafp.org)
Depending on the genetic background of the model, pristane injection can trigger a local inflammatory response (lipogranuloma), erosive arthritis that resembles rheumatoid arthritis, and systemic lupus erythematosus, followed by autoantibody formation and many clinical manifestations [ 3 - 5 ]. (hindawi.com)
Systemic AA amyloidosis is a life-threatening complication of different chronic infectious and inflammatory diseases. (biomedcentral.com)

Because of this evolving etiology of diarrhea in children, it is necessary to clarify the spectrum of clinical manifestations of diarrhea to better inform interventions and surveillance systems, particularly in low- and middle-income countries (LMICs), where the burden of diarrhea is highest ( 1 - 4 ). (cdc.gov)
Gout is the most common inflammatory arthritis with a diverse spectrum of clinical manifestations. (bmj.com)

Vogt-Koyanagi-Harada syndrome is a multisystem disease of presumed autoimmune etiology that is characterized by chronic, bilateral, diffuse, granulomatous panuveitis with accompanying integumentary, neurologic, and auditory involvement. (aao.org)

Rosacea is a common chronic cutaneous disorder of unknown etiology which occurs most commonly in middle-aged individuals. (karger.com)
Cutaneous manifestations include transient or persistent facial erythema, telangiectasia, edema, papules and pustules that are usually confined to the central portion of the face. (karger.com)
Cutaneous manifestations of cirrhosis include jaundice, spider angiomata, skin telangiectasias ("paper money skin"), palmar erythema, white nails, disappearance of lunulae, and finger clubbing, especially in the setting of hepatopulmonary syndrome. (medscape.com)

Bartonellosis is an infectious disease produced by bacteria of the genus Bartonella.Bartonella species cause diseases such as Carrión's disease, trench fever, cat-scratch disease, bacillary angiomatosis, peliosis hepatis, chronic bacteremia, endocarditis, chronic lymphadenopathy, and neurological disorders. (wikipedia.org)
However, it is known that sleep disturbance can be one of the manifestations of various diseases, physiological and pathological conditions, as well as a consequence of medication. (azlawhelp.org)
They may be confused with diseases such as chronic fatigue syndrome, rheumatoid arthritis, multiple sclerosis, depression, and even Alzheimer's disease . (sharecare.com)
The morbidity and mortality profile changes in an older population and contributes to a higher occurrence of chronic diseases, which are more prevalent among women 4-6 . (rrh.org.au)
Although diseases and disabilities are not necessarily correlated with the aging process, chronic degenerative diseases have a higher incidence among the elderly. (rrh.org.au)
Chronic non-communicable diseases are one of the biggest public health problems worldwide 7 . (rrh.org.au)
Among the diseases that affect the osteoarticular system - musculoskeletal disorders with or without tissue damage - many of them cause chronic pain 8 , which negatively affects the health of the elderly 9 . (rrh.org.au)

Bartonella species also have a tropism for endothelial cells, observed in the chronic phase of Carrion's disease (also known as verruga Peruana) and bacillary angiomatosis. (wikipedia.org)
Chronic hepatitis B (CHB) is a viral disease, common across the world, and associated with several extraintestinal manifestations including vasculitis. (hindawi.com)
And contrary to popular belief, chronic Lyme disease isn't a recognized medical diagnosis, according to Danial Kaswan, MD, an infectious disease specialist affiliated with Aventura Hospital and Medical Center in Aventura, Florida. (sharecare.com)
These discoveries have prompted research interest in SU and xanthine oxidoreductase (XOR), an enzyme that produces both urate and ROSs, as status or progression biomarkers of chronic kidney disease and cardiovascular disease. (researchgate.net)
Asthma is considered a syndrome that groups different forms of disease, in which genetic and environmental factors interact and generate manifestations of the disease. (pap.es)
Asthma is a chronic lung disease which causes wheezing, coughing, and breathing difficulty . (diagnose-me.com)
6 Although postherpetic neuralgia (PHN), defined as chronic, often incapacitating, dermatomal pain persisting more than 90 days, affects primarily people with HZ onset age 60 years and older, younger-onset patients suffer from acute pain with a mean duration of approximately 1 month, and are at risk for other complications, including, but not limited to, vision-threatening chronic eye disease. (bmj.com)
Moreover, the identification of determinants to disease manifestation has thus far been elusive. (ebi.ac.uk)
In alignment with the targets of the NTD roadmap, addressing schistosomiasis requires a paradigm shift for its control and management including a greater focus on chronic forms of the disease. (bvsalud.org)
This is especially true for patients with chronic Lyme disease or multiple infections. (txlymealliance.org)
The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (edu.au)
Most patients have mild chronic disease or intermittent flares with periods of remission. (medscape.com)
The hallmark of disease are infections with catalase-positive organisms, especially deep-seated abscesses, osteomyelitis, and chronic granulomata. (lu.se)
Chronic liver disease (CLD) patients, including those with viral hepatitis, autoimmune hepatic disease and schistosomiasis, have an impact on dental practice. (who.int)
This is because patients with chronic liver disease may ultimately develop serious liver dysfunction and this poses problems in performing non-invasive and invasive dental treatment procedures. (who.int)

Chronic hepatitis patients often develop hepatic cirrhosis and progress to liver cancer. (go.jp)
For more than 50% of patients, HCV develops into chronic hepatitis and has become the principal cause of cirrhosis of the liver and hepatocellular carcinomas. (rapidtest.com)

The aim of this study is to clarify clinical features of ADV-related HO in Chinese chronic hepatitis B patients with long-term ADV treatment in Chinese and non-Chinese comparative case series. (biomedcentral.com)
To further determine the clinical features of ADV-induced HO in Chinese chronic hepatitis B patients, we investigated the demographics, clinical spectrum, laboratory tests, treatment and prognosis of ADV-induced HO through a comparison of Chinese and non-Chinese case series. (biomedcentral.com)

Prospective registry study for children and young adults with severe immune cytopenias (persisting/chronic immune thrombocytopenia, autoimmune hemolytic anemia, and Evans syndrome) to improve the management, facilitate the differential diagnostic work-up, and document the clinical course under various treatments. (centerwatch.com)

Moreover, it is important to determine whether HBV stimulates ANCA formation without triggering vasculitis or other immune related manifestations. (hindawi.com)
Autoimmunity affects the cerebellum, leading to the manifestations of the cerebellar ataxias (CAs), termed immune-mediated cerebellar ataxia (IMCAs). (springer.com)

Online Facebook group "Chronic Spontaneous Urticaria After COVID-19 Vaccine Support Group, " 6k members. (researchgate.net)

Persistent cryoglobulinemia after treatment with direct-acting antiviral agents is not uncommon in daily practice. (nejm.org)
In order to gauge the extent of progressive liver impairment and in aiding antiviral treatment, it is vitally important and useful for the chronic hepatitis C patients to know the detectable amounts of HCV IgM that are present. (rapidtest.com)

The multisystemic inflammatory syndrome in children (MIS-C) temporarily associated with COVID-19 is even more severe and presents important cardiac manifestations. (fapesp.br)
BACKGROUND: We evaluated clinical and laboratory findings among patients with non-severe or severe dengue in Puerto Rico to examine whether clinical manifestations vary by age. (cdc.gov)

Notably, the mechanisms that link synaptic dysfunction with the manifestations of CAs can be explained by disruption of the "internal models. (springer.com)
Various studies have reported that adefovir dipivoxil (ADV) can cause proximal renal tubular complex dysfunction, hypophosphatemic osteomalacia (HO) and even Fanconi syndrome since it was first used in the long-term treatment of chronic hepatitis B in 2002 [ 3 ]. (biomedcentral.com)

Other less common chronic manifestations involve the pulmonary, cardiac, and gastrointestinal systems. (medscape.com)

Psychiatric causes can be the manifestations of anxiety, depression, anger and chronic conflicts apart from drug abuse including alcohol. (vardaan.net)
Persistent depressive disorder can be understood as a state of frequent depression, chronic depression. (easyhealthylive.com)
Persistent depressive disorder is also known by other names such as chronic depression, chronic depression. (easyhealthylive.com)
Brain chemicals: The effects of neurotransmitters in the brain are also one of the causes of depression as well as persistent depressive disorder. (easyhealthylive.com)
External influences: Most people with persistent depression have experienced an event that is beyond their normal tolerance. (easyhealthylive.com)
For example, work, debt, loss of loved ones, being cheated on… These situations, if not quickly resolved, will make the patient's spirit always in a state of melancholy and stress, leading to persistent depression. (easyhealthylive.com)

This phase lasts weeks to months and is followed by a chronic phase characterized by sclerodermoid skin changes, neuropathy, neurocognitive deficits, continued myalgia, and muscle cramps. (medscape.com)
however, persistent deficits may remain. (aao.org)

inadequate warning for acute and chronic exposures. (cdc.gov)

Understanding the causes of your teeth grinding can help you identify triggers and take steps to manage it before it becomes a chronic problem that affects your overall health and well-being. (royaldentalcentre.com)

Modern life in USA is associated with chronic persistent stress, unfavorable ecology, disruption of diet, sleep and rest. (azlawhelp.org)

Persistent and clinical aspects, since it may involve individual risk debilitating neck pain resulting from car accidents factors (either physical or emotional characteristics), are also common3 , 8. (bvsalud.org)

Patients can develop two clinical phases: an acute septic phase and a chronic eruptive phase associated with skin lesions. (wikipedia.org)
In considering the nature of chronic fatigue syndrome, the First Circuit noted that chronic fatigue syndrome is diagnosed partially through a process of elimination and an "extended medical history of 'nothing-wrong' diagnoses" is not unusual for CFS patients. (theatlantasocialsecurityattorney.com)
Chronic pain and stiffness are the most common complaints of patients with AS. (medscape.com)
Il est nécessaire de veiller à l'adéquation des prescriptions de médicaments et d'effectuer un suivi plus vigilant des patients dans le cadre clinique et en laboratoire. (who.int)
The first life-threatening or results in persistent or was filled in for all admitted patients, cover- significant disability [ 7 ]. (who.int)

Specifically, this guide urges physicians and other health care the most common clinical manifestations of foodborne ill- professionals to nesses. (cdc.gov)
One of the common physical manifestations of stress is teeth grinding or bruxism. (royaldentalcentre.com)

When it becomes inflamed over an extended period, it leads to chronic pancreatitis, a condition that can be both painful and debilitating. (localquoter.net)

are responsible for an increasing proportion of diarrhea, and these pathogens might have different clinical manifestations ( 5 - 7 ). (cdc.gov)

In response to the growing class of Social Security disability claimants diagnosed with chronic fatigue syndrome (CFS), the Social Security Administration (SSA) issued SSR 99-2p setting forth the SSA's position on CFS. (theatlantasocialsecurityattorney.com)

There are also specific biomarkers for rheumatoid arthritis that are used to diagnose this chronic inflammatory condition. (sharecare.com)

citation needed] The chronic manifestation consists of a benign skin eruption with raised, reddish-purple nodules (angiomatous tumours). (wikipedia.org)
Some people have no skin manifestations. (sharecare.com)

This long-lasting ailment necessitates a thorough understanding of its manifestations to ensure timely intervention and proper care. (localquoter.net)

The present study aimed to estimate the prevalence of self-reported chronic low back pain and to identify the associated factors in elderly people living in rural riverside areas in the Amazon. (rrh.org.au)
The outcome was self-reported chronic back pain or problem. (rrh.org.au)
The prevalence of chronic back pain among the elderly residents was 57.5% (63.3% among men and 50.0% among women). (rrh.org.au)
The chronic low back pain was also associated with worse self-perceived health (OR=10.3, 95%CI=1.6-67.5). (rrh.org.au)
The high prevalence of chronic low back pain in elderly people living in rural riverside areas, along with limited access to treatment and the different impacts on the performance of daily activities and the quality of life, reveals the relevance of this condition as a public health problem. (rrh.org.au)
Pain management becomes a critical component of living with chronic pancreatitis, necessitating a strong partnership between patient and healthcare provider. (localquoter.net)
From medications to lifestyle adjustments, each element plays a role in mitigating the impact of this persistent upper abdominal pain. (localquoter.net)
But with the right support and management strategies, this persistent upper abdominal pain, while intrusive, can be tamed, allowing individuals to reclaim a sense of normalcy in their lives. (localquoter.net)
While occasional teeth grinding is not harmful, persistent bruxism can cause dental problems like worn-down teeth and jaw pain. (royaldentalcentre.com)
Therefore it is difficult to define accurately, The different dimensions of chronic spinal pain at a single stroke, the prevalence of cervical pain. (bvsalud.org)

If you have fatigue on a frequent and chronic basis, develop the evidence regarding your functional limitations. (theatlantasocialsecurityattorney.com)

There is no specific treatment, and manifestations of the syndrome are treated symptomatically. (theatlantasocialsecurityattorney.com)
Despite the variety of clinical and laboratory manifestations, female endocrine infertility is always associated with a violation of the ovulation process: anovulation, luteal phase insufficiency, luteinization syndrome of a non-ovulating follicle. (clomid-info.com)

Nevertheless, the contribution of IL-11Ra1 to the manifestation of phenotypic features of non-atopic asthma are not presently known. (cdc.gov)
Some of those agents are highly poisonous and chronic, features that may render a site uninhabitable and require pricey and doubtlessly hazardous decontamination and remediation. (atpobtvs.com)

Comparisons involving demographics, clinical manifestations, tests, treatment and prognosis were conducted between the two groups. (biomedcentral.com)

Anatomy6

Organisms1

Diseases179

Chemicals and Drugs19

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Psychiatry and Psychology1

Phenomena and Processes14

Disciplines and Occupations1

Information Science5

Named Groups1

Health Care15

Geographicals3

Infection30

Symptoms13

Recurrent7

Symptom4

Inflammation10

Asymptomatic1

Systemic3

Spectrum of clinical manifestations2

Granulomatous1

Cutaneous3

Diseases7

Disease15

Cirrhosis2

Clinical features2

Autoimmune1

Immune2

Urticaria1

Antiviral2

Severe2

Dysfunction2

Cardiac1

Depression6

Deficits2

Acute and chronic1

Affects1

Disruption1

Involve1

Patients5

Common2

Painful1

Diarrhea1

Fatigue syndrome1

Arthritis1

Skin2

Timely1

Pain10

Frequent1

Syndrome2

Features2

Treatment1