Chronic intestinal. Medical search. Frequent questions

The disorder also impairs the rhythmic muscle contractions that propel food through the intestines (peristalsis), causing a digestive condition called intestinal pseudo-obstruction . (medlineplus.gov)
In intestinal pseudo-obstruction, impairment of peristalsis leads to a buildup of partially digested food in the intestines, abdominal swelling (distention) and pain, nausea, vomiting, and constipation or diarrhea. (medlineplus.gov)
These symptoms resemble those caused by an intestinal blockage (obstruction) such as a tumor, but in intestinal pseudo-obstruction no such blockage is found. (medlineplus.gov)
Chronic intestinal pseudo-obstruction (CIPO) is a rare disorder characterized by an impairment of coordinated propulsive activity in the gastrointestinal (GI) tract, which clinically mimics mechanical intestinal obstruction. (nih.gov)
Intestinal pseudo-obstruction (IPO) is a clinical syndrome caused by severe impairment in the ability of the intestines to push food through. (wikipedia.org)
One retrospective study estimated mortality to be between 10 and 25% for chronic intestinal pseudo-obstruction (CIPO) and to vary greatly depending on the etiology of the condition. (wikipedia.org)
Mechanical causes of intestinal obstruction must be excluded to reach a diagnosis of pseudo-obstruction. (wikipedia.org)
The aim of this study was to report the presentation and outcome of 22 consecutive children (13 female) who presented with a syndrome of chronic intestinal pseudo-obstruction with or without urinary tract involvement. (elsevierpure.com)

Here, we report that during intestinal inflammation, multiple inflammatory cytokines promote the activity of a master regulator of cell proliferation and apoptosis, serine/threonine kinase CK2. (diva-portal.org)
These observations identify CK2 as a key regulator of homeostatic properties of the intestinal epithelium that serves to promote wound healing, in part through inhibition of apoptosis under conditions of inflammation. (diva-portal.org)
Additionally, when dietary emulsifiers cause changes in the gut microbiome, the protective mucosal lining of the gut may no longer be able to keep out bad microbes, potentially causing chronic intestinal inflammation. (medicalnewstoday.com)
Additionally, researchers discovered that flagellin immunization appeared to help protect the mice from chronic intestinal inflammation and metabolic dysregulations typically seen after ingesting dietary emulsifiers. (medicalnewstoday.com)
There are growing concerns that daily oral TiO 2 -NP intake is associated with an increased risk of chronic intestinal inflammation and carcinogenesis. (nature.com)
E171 or NM-105 for one week did not initiate intestinal inflammation, while a 100-day E171 treatment promoted colon microinflammation and initiated preneoplastic lesions while also fostering the growth of aberrant crypt foci in a chemically induced carcinogenesis model. (nature.com)
Life stress and mucosal inflammation may influence symptom onset and severity in certain gastrointestinal disorders, particularly irritable bowel syndrome (IBS), in connection with dysregulated intestinal barrier. (nih.gov)
Our aims were to prove that crowding stress induces mucosal inflammation and intestinal dysfunction, to characterize dynamics in time, and to evaluate the implication of stress-induced mast cell activation on intestinal dysfunction. (nih.gov)
Stress-induced intestinal chrono-pathobiology was determined by measuring intestinal inflammation, epithelial damage, mast cell activation and infiltration, and intestinal barrier function. (nih.gov)
IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells. (ox.ac.uk)
Here, we used two complementary models of chronic intestinal inflammation to address the role of IL-1β in driving innate and adaptive pathology in the intestine. (ox.ac.uk)
We show that IL-1β promotes innate immune pathology in Helicobacter hepaticus-triggered intestinal inflammation by augmenting the recruitment of granulocytes and the accumulation and activation of innate lymphoid cells (ILCs). (ox.ac.uk)

Targeting specific proteins could help bolster the gut microbiome against some chronic conditions. (medicalnewstoday.com)
Fusobacteria and Verrucomicrobia at phylum level were increased in lung microbiome by air pollution, whereas increased alpha diversity, Bacteroidetes and Proteobacteria and decreased Firmicutes at phylum level were occurred in intestinal microbiome. (nycu.edu.tw)
Lung function decline was correlated with increasing antibiotics, drugs, and metals in lungs as well as lung and intestinal microbiome dysbiosis. (nycu.edu.tw)
The lung microbiome was correlated with intestinal microbiome at several phylum and family levels after air pollution exposure. (nycu.edu.tw)
Our results revealed that antibiotics, drugs, and metals in the lung caused lung and intestinal microbiome dysbiosis in ageing rats exposed to air pollution, which may lead to lung function decline. (nycu.edu.tw)

The diagnostic approach includes the need for investigations to exclude mechanical GI obstruction, screening for causes of secondary CIPO and the identification of the disease phenotype as well as the prompt recognition and treatment of complications such as malnutrition and small intestinal bacterial overgrowth. (nih.gov)
They are at such risk that they need small intestinal transplantation as well. (cincinnatichildrens.org)
Human small intestinal juice was chosen as incubation medium. (karger.com)

It is characterized by the signs and symptoms of intestinal obstruction without any lesion in the intestinal lumen. (wikipedia.org)
A diagnostic work-up may include: Gastric motility studies Imaging studies: X-rays - may show intestinal air fluid levels (seen with true mechanical intestinal obstruction) CT scans Barium enema Blood tests Upper and lower endoscopies Manometry - used to measure pressure of esophagus and stomach Treatment for IPO (acute or chronic) is aimed at removing the disease process and/or managing the complications present. (wikipedia.org)
Ten patients had signs of intestinal obstruction at birth, in which 6 presented antenatally with megacystis on ultrasound. (elsevierpure.com)

Our findings suggest that targeting flagellated bacteria within the intestinal tract could offer innovative ways to beneficially modulate the intestinal microbiota in order to protect against an array of microbiota-related chronic inflammatory diseases, such as inflammatory bowel diseases and metabolic disorders . (medicalnewstoday.com)
which acts principally in the bowel lumen for the treatment of diarrhea and intestinal amebiasis, particularty for cyst passers.Streptomycin sulfate is poorly absorbed from the gastro-intestinal tract and may be of value in the treatment of diarrhea caused by E. coli, Proteus vulgaris and other susceptible organisms. (medicinep.com)
Clinical features mimic those seen with mechanical intestinal obstructions and can include abdominal pain, nausea, abdominal distension, vomiting, dysphagia and constipation depending upon the part of the gastrointestinal tract involved. (wikipedia.org)
Thus, this article reviews the involvement of the cannabinoid system in chronic inflammatory diseases that affect the gastrointestinal tract and highlights possible therapeutic approaches related to the use of cannabinoids. (irjournal.org)
Because some patients have disorders of the nerves or muscles of the gastrointestinal tract, the movement of food down the gastrointestinal tract may be so disorganized that they develop intestinal failure needing intravenous nutrition. (cincinnatichildrens.org)
Intestinal lymphangiectasia (IL), a rare form of protein losing enteropathy, is a benign condition characterized by focal or diffuse dilation of the mucosal, submucosal, and subserosal lymphatics causing loss of lymph fluid into the gastrointestinal tract, leading to edema, hypoproteinemia, lymphocytopenia, hypogammaglobulinemia, and immunological abnormalities. (wjwch.com)
In this test, a small camera, attached to a tube, will be passed through your dog's mouth or anus into the intestines so that the walls of the stomach and intestinal tract can be closely inspected for ulcers, tissue masses (tumors), or abnormalities in the wall or cell structure. (petmd.com)
The immune system's attempt to eliminate Salmonella bacteria from the gastrointestinal (GI) tract instead facilitates colonization of the intestinal tract and fecal shedding, according to scientists. (sciencedaily.com)
One of the first lines of defense in the GI tract is the physical barrier provided by a single layer of intestinal epithelial cells. (sciencedaily.com)
Then they infected laboratory mice with the self-destructing Salmonella bacteria and found that replication in the cytosol of mouse intestinal epithelial cells is important for colonization of the GI tract and fuels fecal shedding. (sciencedaily.com)

Advances in the medical and surgical treatments of intestinal failure have led to a decrease in the number of transplants over the past decade. (medscape.com)
Nevertheless, intestine transplant still plays an important role in the treatment of intestinal failure. (medscape.com)
Clinical, Economic, and Humanistic Impact of Short-Bowel Syndrome/Chronic Intestinal Failure in Portugal (PARENTERAL Study). (bvsalud.org)
Symptoms indicative of advanced disease and possible intestinal failure include diarrhea, loss of appetite, sepsis, bloating, fatigue, signs of low volume status, and malabsorption including nutritional deficiencies and foul-smelling stools. (wikipedia.org)
When liver failure complicates intestinal failure, we transplant the liver along with the intestine. (cincinnatichildrens.org)
Children with this disorder usually present in the first 3 years of life, [ 1 ] initially with chronic diarrhea causing failure to thrive, and later with features of malabsorption, micronutrient deficiency, hypoproteinemia, and generalized edema. (wjwch.com)
12th Annual Salford ESPEN-endorsed Workshop on Acute and Chronic Intestinal Failure The 12th Annual ESPEN Intestinal Failure Workshop will take place as in-person event next year on the 22nd and 23rd of March 2024. (espen.org)

Therefore, cannabinoids are interesting pharmacological compounds for the treatment of several acute intestinal disorders, such as dysmotility, emesis, and abdominal pain. (irjournal.org)
It can be acute, lasting only days or chronic, lasting weeks or months. (vetinfo.com)
The particles reduced acute colitis and prevented chronic colitis and colitis-associated cancer. (scienceblog.com)

Different patterns of intestinal transit time and anorectal motility in painful and painless chronic constipation. (bmj.com)
Treatment targets nutritional support, improving intestinal motility, and minimizing surgical intervention. (wikipedia.org)

However, in previous studies, NIAID scientists had observed that some Salmonella replicate rapidly in the cytosol -- the fluid portion -- of intestinal epithelial cells. (sciencedaily.com)
Ancillary tests included aerobic bacterial culture of liver, spleen, and lung tissue and real-time PCR for Salmonella species in intestinal contents, for avian influenza virus and avian paramyxovirus-1 on an oropharyngeal swab sample, and for West Nile virus in kidney tissue. (cdc.gov)

Five cases of intestinal toxemia botulism in adults were identified within an 18-month period in or near Toronto, Ontario, Canada. (cdc.gov)

Detect chronic intestinal disorders? (bloodtesting.nl)
The notable resemblance of these findings with those in some IBS patients, support the potential interest and translational validity of this experimental model for the research of stress-sensitive intestinal disorders, particularly IBS. (nih.gov)
In concert with chronic visceral pain, there is a high comorbidity with stress-related psychiatric disorders including anxiety and depression. (frontiersin.org)
Evidence suggests that long term stress facilitates pain perception and sensitizes pain pathways, leading to a feed-forward cycle promoting chronic visceral pain disorders such as irritable bowel syndrome (IBS). (frontiersin.org)
Protein hydrolysates have been used successfully to treat cats with psychogenic alopecia and chronic gastrointestinal disorders. (entirelypets.com)

This instability is thought to cause early aging (senescence) of cells in the intestinal muscle and in the SA node, resulting in problems maintaining proper rhythmic movements of the heart and intestines and leading to the signs and symptoms of CAID. (medlineplus.gov)
Gastro-intestinal symptoms, headache and allergic skin reactions rnay occur rarely. (medicinep.com)
What Are The Signs & Symptoms of Chronic Intestinal Yeast? (planetayurveda.net)
The condition can cause several symptoms, including chronic pelvic pain , painful periods , and infertility . (medicalnewstoday.com)
The most common symptoms are chronic pelvic pain and painful periods. (medicalnewstoday.com)

This poster presents a quantitative risk assessment based on a NTP chronic bioassay, in which rats and mice were exposed to 125-500 or 62.5-250 ppm 1-BP, respectively, for up to 2 years. (cdc.gov)
The aim of the study was to examine the influence of prebiotic - gum acacia (GA) on the intestinal microbiota in rats with adenine-induced CKD. (elsevierpure.com)

Likewise, the role of cannabinoids in the treatment of chronic intestinal diseases, such as irritable bowel syndrome and inflammatory bowel disease, is also under investigation. (irjournal.org)

[ 5 ] The first intestinal transplant in humans was performed by Deterling in Boston in 1964 (unpublished data). (medscape.com)

As genetic susceptibility contributes to a large proportion of chronic inflammatory intestinal diseases, we hypothesize that the genomic regions surrounding established genome-wide associated variants for these chronic inflammatory diseases are associated with PDAC. (upf.edu)
This could offer a potential new way to train the mucosal immune system to help protect against chronic inflammatory diseases such as type 2 diabetes and obesity. (medicalnewstoday.com)
Patients with chronic intestinal inflammatory diseases present impaired quality of life, and mental health issues are commonly associated with long-term chronic diseases. (irjournal.org)

This is most often caused by chronic Helicobacter pylori infection. (medscape.com)
One of these infections is Chronic Intestinal yeast Infection. (planetayurveda.net)
This is at number one for causing overgrowth of yeast infection and one of the studies have shown that 58 percent of the people suffer from intestinal infection. (planetayurveda.net)

Enhanced mucosal CK2 protein expression and activity were observed in animal models of chronic colitis, particularly within intestinal epithelial cells (IECs). (diva-portal.org)

These bacteria, also called intestinal flora, have a healthy impact on your health. (healthline.com)

Chronic kidney disease (CKD) is a globally common and important disease and there are evidence for a bidirectional relationship between microbiota and CKD. (elsevierpure.com)

Today, I want to talk about the management of gastric intestinal metaplasia (GIM). (medscape.com)
There are two instruments used for histopathologic assessment that can portend greater risk for progression: the operative link on gastritis assessment (OLGA) and the operative link on gastric intestinal metaplasia assessment (OLGIM) staging systems. (medscape.com)
This can be a key step in the development of intestinal metaplasia often observed in esophagus-cardia junction. (silverchair.com)

SIGNIFICANCE: The joint effects of common variants in genomic regions containing susceptibility loci for inflammatory bowel disease and chronic pancreatitis are associated with PDAC and may provide insights to understanding pancreatic cancer etiology. (upf.edu)
Despite careful histological study pointing to 2 main forms, myopathy and neuropathy, the etiology of primary intestinal pseudoobstruction syndromes remains unknown. (elsevierpure.com)

To explore mechanisms whereby Malpighian keratinocytes can transdifferentiate into an intestinal-like epithelium, as observed in the early steps of Barrett's esophagus (BE) development, long-standing cultures of esophageal keratinocytes derived from normal mouse esophageal explants were developed. (silverchair.com)

In the United States, surveys have shown that more than half of American adults suffer from chronic gut and stomach discomfort. (iherb.com)
When an isolated intestinal transplant is considered, the native stomach, small bowel, and liver are maintained and the only organ transplanted is the small intestine. (cincinnatichildrens.org)

Registry-based epidemiologic studies suggest associations between chronic inflammatory intestinal diseases and pancreatic ductal adenocarcinoma (PDAC). (upf.edu)
Our results support the hypothesis that genomic regions surrounding variants associated with inflammatory intestinal diseases, particularly, ulcerative colitis, Crohn disease, inflammatory bowel disease, and chronic pancreatitis are associated with PDAC. (upf.edu)
Detecting chronic intestinal diseases? (bloodtesting.nl)
Although very high levels of interleukin (IL)-1β are present in the intestines of patients suffering from inflammatory bowel diseases (IBD), little is known about the contribution of IL-1β to intestinal pathology. (ox.ac.uk)
Chronic restrictive diseases: classification of various types of histological patterns in interstitial lung disease (usual interstitial pneumonia, nonspecific interstitial pneumonia). (unibo.it)

As of February 2021, the Organ Procurement and Transplant Network (OPTN) listed 214 patients awaiting intestinal transplantation. (medscape.com)
The Intestinal Transplant Program at Cincinnati Children's provides comprehensive, innovative care for patients with short bowel syndrome , congenital enteropathies and pseudo-obstructions. (cincinnatichildrens.org)
Some patients are able to avoid it by participating in our Intestinal Rehabilitation Program, which offers extensive treatment options and training to help patients manage their long-term medical needs. (cincinnatichildrens.org)
Other patients have the option of undergoing autologous intestinal reconstructive surgery (e.g., bowel lengthening and tapering) in order to preserve bowel function and avoid transplant. (cincinnatichildrens.org)
Patients with chronic pan- at 56 ºC overnight. (who.int)
Evans M, Carrero JJ, Bellocco R, Barany P, Qureshi AR, Seeberger A, Jacobson SH, Hylander-Rössner B, Rotnitzky A, Sjölander A. Initiation of erythropoiesis-stimulating agents and outcomes: a nationwide observational cohort study in anaemic chronic kidney disease patients. (janusinfo.se)

The in vitro treatment of intestinal epithelial cell lines with cytokines resulted in increased CK2 expression and nuclear translocation of its catalytic alpha subunit. (diva-portal.org)

As with the transplantation of other organs, the history of intestinal transplantation begins with Carrel and his description of a method of performing vascular anastomosis. (medscape.com)
[ 3 , 4 ] In 1959, the first canine model of intestinal transplantation was reported by Lillihei and coworkers at the University of Minnesota. (medscape.com)

The first reported human intestinal transplant was performed by Lillihei and coworkers in 19677. (medscape.com)
In 1988 Deltz and coworkers in Kiel, Germany, performed what is considered to be the first successful intestinal transplant. (medscape.com)
[ 7 ] and Grant and coworkers in London, Canada, who had established the first intestinal transplant programs. (medscape.com)

Bacterial overgrowth of the small intestine can occur in chronic cases - presenting as malabsorption, diarrhea, and nutrient deficiencies - which may require the use of antibiotics. (wikipedia.org)

Dhuri BR, Rao S, Shah I, Shah D, Tetarbe S. Chronic diarrhea in a toddler - A case of intestinal lymphangiectasia. (wjwch.com)

Assess the clinical presentation of adult intestinal toxemia botulism. (cdc.gov)
Clinical samples contained Clostridium botulinum spores and botulinum neurotoxins (types A and B) for extended periods (range 41-61 days), indicative of intestinal toxemia botulism. (cdc.gov)

We examined the association between PDAC and genomic regions (±500 kb) surrounding established common susceptibility variants for ulcerative colitis, Crohn's disease, inflammatory bowel disease, celiac disease, chronic pancreatitis, and primary sclerosing cholangitis. (upf.edu)

Your veterinarian will order stool (fecal) tests to check for intestinal parasites, intestinal infections, and other indicators that your dog is losing protein from its intestines. (petmd.com)

3- Diarrnea caused by other intestinal infections and associated with intestinal colic. (medicinep.com)
Title : Study of intestinal helminth infections in a coastal South Carolina area Personal Author(s) : Jeffery, Geoffrey M.;Phifer, Kenneth O.;Gatch, Donald E.;Harrison, Andrew J.;Skinner, Jimmie C. (cdc.gov)

Although the science of the epigenetics of human pain management is in its early stages with relatively few studies that have examined epigenetically mediated mechanisms involved in nociception in human subjects, a key aspect of the review will be to highlight the latest insights into epigenetic processes, including DNA methylation, histone modifications and microRNAs, and describe their involvement in the pathophysiology of chronic visceral pain. (frontiersin.org)

Evaluate the epidemiology and microbiology of adult intestinal toxemia botulism. (cdc.gov)

These noncardia intestinal-type gastric cancers follow a stepwise progression known as the Correa cascade. (medscape.com)

In primary CIPO (the majority of chronic cases) the condition results from disruption of the intestine's ability to move food. (wikipedia.org)

The molecular mechanisms that restore intestinal epithelial homeostasis during colitis are incompletely understood. (diva-portal.org)

ELS models such as maternal separation, limited nesting, or odor-shock conditioning, which attempt to model early childhood experiences such as neglect, poverty, or an abusive caregiver, can produce chronic, sexually dimorphic increases in visceral sensitivity in adulthood. (frontiersin.org)
Chronic visceral pain is a classic example of gene × environment interaction which results from maladaptive changes in neuronal circuitry leading to neuroplasticity and aberrant neuronal activity-induced signaling. (frontiersin.org)
This review will discuss the potential neuronal pathways and mechanisms responsible for stress-induced exacerbation of chronic visceral pain. (frontiersin.org)
Chronic visceral pain describes persistent pain emanating from the thoracic, pelvic, or abdominal organs that is poorly localized with regard to the specific organ affected. (frontiersin.org)
We will explain the unique aspects of these models that allows for a carefully crafted investigation of the female vulnerability to stress-induced chronic visceral pain. (frontiersin.org)

Primary intestinal lymphangiectasia (PIL) or Waldmann's disease was first described by Waldmann in 1961. (wjwch.com)
Ischemic heart disease: pathogenesis and morphological features of angina pectoris, chronic ischemic heart disease, myocardial infarction (timing of the progression of ischemic necrosis in myocardial infarction: evaluation methods). (unibo.it)
Non-neoplastic smoke-related lung disease: chronic obstructive pulmonary disease, small airways disease/respiratory bronchiolitis, Langerhans cell histiocytosis of the lung. (unibo.it)
Association Between Proton Pump Inhibitor Use and Risk of Progression of Chronic Kidney Disease. (janusinfo.se)

These findings demonstrate that chronic exposure of esophageal keratinocytes to acid pH induces transcription of cdx 2, an intestinal specific homeobox gene known to play a critical role in the differentiation and maintenance of intestinal epithelial functions. (silverchair.com)

We will provide an evidenced-based argument for the use of specific experimental models to advance the understanding of stress-induced chronic pain. (frontiersin.org)

These data identify multiple mechanisms through which IL-1β promotes intestinal pathology and suggest that targeting IL-1β may represent a useful therapeutic approach in IBD. (ox.ac.uk)

The physiologic effects of truncal vagotomy on acid secretion had been known since the early 19th century, and this approach was introduced to the treatment of chronic duodenal ulcer in the 1940s. (medscape.com)

Furthermore, external acid environment triggered expression of the GFP reporter gene fused downstream of the cdx 2 intestinal homeogene regulatory sequences in P3E6 transfected cells. (silverchair.com)

Get your gut tested and find the cause of chronic conditions and get nutritional and supplementation recommendations to restore your gut flora with one of our gut tests. (bloodtesting.nl)

Because chronic exposure to acid pH is known to be a critical factor for BE development,culture medium at pH 3.5 was added into the apical chamber of cell cultures. (silverchair.com)
The results suggest that chronic acid exposure can modify the fate of P3E6 esophageal keratinocytes towards an intestinal program. (silverchair.com)

Analyze risk factors for adult intestinal toxemia botulism. (cdc.gov)

however, it is also found in cardiovascular, intestinal, and reproductive systems, as well as bones and adipocytes, being largely expressed in immune cells [ 8 ]. (irjournal.org)

Chronic, progressive GI issues are common, but also swallowing muscles oral pharyngeal muscles can be affected, and that's an important risk in a surgical procedure, any procedure. (umdf.org)

Diseases1

Technology, Industry, Agriculture4

Humanities1

Information Science1

Pseudo-obstruction8

Inflammation12

Microbiome5

Small intestinal3

Obstruction3

Tract10

Failure7

Acute3

Motility2

Salmonella2

Cases of intestinal1

Disorders5

Symptoms5

Rats2

Irritable bowel sy1

Humans1

Inflammatory diseases3

Infection3

Epithelial Cells1

Bacteria1

Microbiota1

Metaplasia3

Etiology2

Epithelium1

Stomach2

Diseases5

Patients6

Cytokines1

Transplantation2

Transplant3

Overgrowth1

Diarrhea1

Clinical2

Ulcerative colitis1

Fecal1

Infections2

Pathophysiology1

Microbiology1

Gastric1

CIPO1

Homeostasis1

Visceral5

Disease4

Induces1

Stress-induced1

Mechanisms1

Treatment1

Gene1

Restore1

Exposure2

Adult1

Immune1

Risk1