Neurodegenerative DiseasesDisease SusceptibilityChronic DiseaseGenetic Predisposition to DiseaseNerve DegenerationPolymorphism, Single NucleotideGenotypeAlzheimer DiseaseBrainAllelesAmyotrophic Lateral SclerosisNeuronsDisease Models, AnimalHaplotypestau ProteinsHuntington DiseaseParkinson DiseasePolymorphism, Geneticalpha-SynucleinMutationGenome-Wide Association StudyGene FrequencyCase-Control StudiesNerve Tissue ProteinsPrionsMice, TransgenicPhenotypeNeuroprotective AgentsTauopathiesPrion DiseasesGenetic VariationMice, Inbred C57BLLinkage DisequilibriumInclusion BodiesHeredodegenerative Disorders, Nervous SystemProteostasis DeficienciesGenetic LinkageMolecular Sequence DataChromosome MappingAgingMicrogliaMicrobial Sensitivity TestsOxidative StressGenetic MarkersSynucleinsCells, CulturedCell DeathAmyloid beta-PeptidesGenome, HumanSpinocerebellar AtaxiasGene Expression RegulationFrontotemporal Lobar DegenerationSignal TransductionModels, BiologicalMitochondriaTrinucleotide Repeat ExpansionImmunity, InnateAmino Acid SequenceRisk FactorsModels, GeneticFrontotemporal DementiaFriedreich AtaxiaHLA-DQ AntigensMice, KnockoutCrohn DiseaseGenetic Association StudiesEpistasis, GeneticNod2 Signaling Adaptor ProteinTime FactorsAutophagyHLA-DRB1 ChainsGuamAmyloidHLA-DR3 AntigenHLA-DQ beta-ChainsNeuronal Ceroid-LipofuscinosesAnti-Bacterial AgentsComplement C4aPlant DiseasesDementiaHLA-DR AntigensGenetic LociCell LinePedigreePeptidesBase SequenceInflammationProtein FoldingAge of OnsetDiseaseGenetic Diseases, InbornSpecies SpecificitySuperoxide DismutaseNeurofibrillary TanglesAstrocytesNeurotoxinsLewy Body DiseaseParkinsonian DisordersPolymerase Chain ReactionApoptosis