• From our results, norfloxacin is an effective and well-tolerated antimicrobial agent for eradicating the chronic typhoid carrier state. (edu.pe)
  • Prompt administration of high-dose dexamethasone reduces mortality in patients with severe typhoid fever without increasing incidence of complications, carrier states, or relapse among survivors. (medscape.com)
  • there is some evidence that being a chronic typhoid carrier may be a factor in the development of the condition under consideration. (dva.gov.au)
  • 10203 the veteran has been a chronic typhoid carrier at some time. (dva.gov.au)
  • the veteran was a chronic typhoid carrier before the clinical onset of the condition under consideration. (dva.gov.au)
  • 10205 - the veteran has established the causal connection between being a chronic typhoid carrier and VEA service for the clinical onset of the condition under consideration. (dva.gov.au)
  • Although 356 cases of typhoid fever were reported in the US in 2003, 3 most of these infections are acquired during travel to other parts of the world or by contact with someone who is a carrier-either someone who has recently traveled or is a chronic carrier of S.Typhi . (immunizationinfo.org)
  • Chronic granulomatous disease (CGD), also known as Bridges-Good syndrome, chronic granulomatous disorder, and Quie syndrome, is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens. (wikipedia.org)
  • The underlying cellular mechanism that causes chronic granulomatous disease was discovered in 1967, and research since that time has further elucidated the molecular mechanisms underlying the disease. (wikipedia.org)
  • Classically, patients with chronic granulomatous disease will have recurrent bouts of infection due to the decreased capacity of their immune system to fight off disease-causing organisms. (wikipedia.org)
  • A dysfunction of phagocyte NOX, on the other hand, results in chronic granulomatous disease (CGD) in humans, characterized by recurrent bacterial and fungal infections as well as granuloma formation and hyperinflammation. (frontiersin.org)
  • Infection with HBV results in a wide spectrum of acute and chronic liver diseases that may lead to cirrhosis and hepatocellular carcinoma. (cdc.gov)
  • In chronic hepatitis B (CHB) patients, liver cirrhosis carries a high risk to develop, as dose hepatocellular carcinoma [ 3 ]. (hindawi.com)
  • High relapse rates and low tolerability to ampicillin characterize present therapy for carriers of Salmonella typhi. (edu.pe)
  • Carriers of S. typhi were treated in a double-blind trial with either norfloxacin (400 mg) or matching placebo given every 12 h for 28 d. (edu.pe)
  • A carrier was defined as a person who had contact with patients, reported no recent illness, and had S. Typhi with either of the PFGE outbreak patterns in an isolate from a rectal swab or stool specimen. (cdc.gov)
  • CDPHE hypothesized that a chronic S. Typhi carrier might be working in food service at restaurant A, where food is prepared using fresh ingredients. (cdc.gov)
  • Some people who become infected with S. Typhi become chronic carriers-they have no symptoms but have S. Typhi in their feces. (immunizationinfo.org)
  • Chronic carriers can spread S. Typhi to other people especially when handling food. (immunizationinfo.org)
  • 3) does not cause chronic liver disease. (slideserve.com)
  • You should take steps to prevent catching or spreading these viruses since these infections can cause chronic liver disease. (medlineplus.gov)
  • Biofilm formation by Salmonella might contribute to both the chronic Salmonella carrier state in pigs and the inefficacy of current measures. (sciensano.be)
  • Biofilm formation by Salmonella in the gut mucosal layer is expectedly an important factor, contributing to both the chronic Salmonella carrier state in the gut of adult pigs and the inefficacy of current measures. (sciensano.be)
  • Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead to cirrhosis, cancer, and liver failure. (wjgnet.com)
  • The peak of the serum miR-122 expression normally occurs in the early stage of the progression from the HBV carrier phase to chronic hepatitis to cirrhosis. (hindawi.com)
  • Chronic HBV infection might go through several stages: chronic HBV carrier phase, CHB, cirrhosis, and ultimately HCC. (hindawi.com)
  • Viral hepatitis is a major public health problem of global importance because of the ongoing transmission of viruses that cause the disease and increased morbidity and mortality associated with the acute and chronic consequences of these infections. (cdc.gov)
  • The surface antigen, HBsAg is a good marker in the estimation of the number of hepatitis B virus (HBV) carriers among a population because its presence shows either an acute viral hepatitis B or a chronic carriage state of the HBV [ 1 - 3 ]. (omicsonline.org)
  • SD has been shown to develop more frequently in patients with chronic viral hepatitis without precursor lesions, whereas LD lesions have been found more frequently in patients with chronic bile duct disease. (medscape.com)
  • Co-infection with hepatitis D virus (HDV) in persons with acute or chronic hepatitis B virus (HBV) infection can lead to fulminant hepatitis. (cdc.gov)
  • Ultrasonography is useful in the evaluation of joints affected by acute or chronic effusions. (medscape.com)
  • There is a large body of evidence to suggest that there is a higher mortality risk and rate of progression of chronic kidney disease in men compared to women, with the exception being in post-menopausal women and diabetic patients. (news-medical.net)
  • To investigate the expression of microRNA-122 (miR-122) in the progression of chronic hepatitis B virus- (HBV-) infected liver diseases, thus determining the role of serum miR-122 as a marker of HBV-caused liver injury. (hindawi.com)
  • Chronic kidney disease is defined as damage of the renal parenchyma that results in chronic deterioration of kidney function and may result in progression to end-stage renal disease. (news-medical.net)
  • There are five stages of kidney damage in chronic kidney disease that range from mild kidney dysfunction to complete failure. (news-medical.net)
  • The burden of chronic kidney disease is increasing worldwide and is becoming increasingly prevalent in developing countries. (news-medical.net)
  • Patients who have stage three or four chronic kidney disease are at a higher risk of progressing to either end-stage renal disease or death. (news-medical.net)
  • chronic kidney disease is found to incur an 8-to-10-fold increased risk for these conditions. (news-medical.net)
  • There is a heritable component associated with chronic kidney disease, as established by genome-wide association studies (GWAS) and GWAS meta-analyses. (news-medical.net)
  • These genetic markers do not account for the totality of susceptibility to chronic kidney disease, despite a genetic association being established, causal pathways are incompletely understood. (news-medical.net)
  • As such, several other factors contribute to the susceptibility of developing chronic kidney disease. (news-medical.net)
  • There are several risk factors associated with the development of chronic kidney disease. (news-medical.net)
  • While the prevalence of chronic kidney disease tends to be greater in women, the disease is typically more severe in men, who also have an increased risk of end-stage renal disease. (news-medical.net)
  • Chronic kidney disease is more prevalent among men than women. (news-medical.net)
  • Family members of chronic kidney disease patients have a high prevalence of chronic kidney disease. (news-medical.net)
  • Consequently, it is advised that those with chronic kidney disease should have high-risk family members screened. (news-medical.net)
  • Hypertension is both a cause and effect of chronic kidney disease and is a common comorbidity in those with chronic kidney disease. (news-medical.net)
  • The control of hypertension is related to a reduced rate of chronic kidney disease progression, as well as a reduced risk of cardiovascular disease. (news-medical.net)
  • However, patients with chronic kidney disease and hypertension often require a combination of non-pharmacological and antihypertensive medication treatment to achieve a target blood pressure. (news-medical.net)
  • con committedly, chronic kidney disease may be a risk factor for cancer, and there is a strong association between the two conditions due to the commonality of risk factors, often toxins. (news-medical.net)
  • Literature has demonstrated that compared with the general population, those who receive a kidney transplant as a result of chronic kidney disease have a three to four-fold increase in overall cancer risk. (news-medical.net)
  • Background and aims: Several susceptibility gene variants predisposing to nonalcoholic fatty liver disease (NAFLD) have been identified in chronic kidney disease (CKD). (lu.se)
  • SCD is suggested by the typical clinical picture of chronic hemolytic anemia and vaso-occlusive crisis. (medscape.com)
  • WATERTOWN, Mass.--(BUSINESS WIRE)--SQZ Biotechnologies (NYSE: SQZ), focused on unlocking the full potential of cell therapies for multiple therapeutic areas, today announced that the first clinical translation of the company's Tolerizing Antigen Carrier (TAC) platform in autoimmune diseases will be for celiac disease, a chronic autoimmune disorder that afflicts millions of patients and has no approved drug treatment. (pharmiweb.com)
  • Inflammatory infiltrate shows an important role in the pathogenesis of chronic chagasic myocarditis [ 6 ] and inflammatory lesions in the enteric nervous system, associated with a drastic reduction in the number of neurons, reinforcing clinical findings in chagasic megacolon/megaesophagus [ 7 - 10 ]. (hindawi.com)
  • Examination of medical records of two of these workers verified a clinical diagnosis of industrial asthma and chronic productive cough, respectively. (cdc.gov)
  • The project will be able to detect chromosomes, genes and proteins which will allow for the prevention of chronic diseases. (alarabiya.net)
  • The Dubai Health Authority (DHA) launched the human genome project on Saturday which perfects gene scanning to help decrease chronic and genetic diseases, Khaleej Times reported. (alarabiya.net)
  • When considering risk factors for chronic diseases (like diabetes and heart disease), family health history is often included in the list of non-modifiable risk factors (like race/ethnicity and age), suggesting that family health history cannot be changed. (cdc.gov)
  • A few infected people develop chronic infection of the gallbladder or urinary tract. (msdmanuals.com)
  • These features are of ethical relevance because they influence the way we traditionally think about infectious disease control and urge us to pay more attention to the personal experience of the individual carrier. (cdc.gov)
  • Intermittent vaso-occlusive crises may be superimposed, or chronic low-level pain may be the only expression of the disease. (medscape.com)
  • Celiac disease is a chronic autoimmune disorder that occurs in genetically predisposed people. (pharmiweb.com)
  • Chronic active Epstein-Barr virus (CAEBV) disease is a rare disorder in which persons are unable to control infection with the virus. (frontiersin.org)
  • This entity is referred to as chronic active EBV (CAEBV) disease. (frontiersin.org)
  • Chronic active Epstein-Barr virus disease is usually defined as a chronic illness lasting at least 6 months, an increased EBV level in either the tissue or the blood, and lack of evidence of a known underlying immunodeficiency ( 15 ). (frontiersin.org)
  • A concanavalin-A-induced suppressor cell assay was carried out in 10 patients with chronic filarial disease, 13 asymptomatic microfilaria carriers and 7 healthy subjects. (karger.com)
  • Diabetes mellitus is a chronic metabolic disease that affects >500 million patients worldwide. (bvsalud.org)
  • Preventing Chronic Disease [serial online] 2004 Jan [ date need to redesign the current surveillance system to cap- cited ]. (cdc.gov)
  • and antimicrobial resistance is a slowly evolving threat on which individual carriers have limited effect. (cdc.gov)
  • Methods used in study of ethics of infection control measures for carriers of antimicrobial-resistant organisms, the Netherlands, January 1, 2008-January 16, 2016. (cdc.gov)
  • ABSTRACT To evaluate the effectiveness of hepatitis B virus (HBV) vaccination of household contacts of HBV carriers in Tulkarm district, Palestine, quantitative hepatitis B surface (anti-HBs) antibody response in 161 household contacts was measured after vaccination. (who.int)
  • These have identified several genetic loci associated with CKD, including variants in UMOD, SHROOM3, solute carriers, and E3 ubiquitin ligases. (news-medical.net)
  • In 50% of cases, it results in perinatal infection, leading to chronic hepatitis B infection of children in up to 90% of cases if no adequate vaccination (active and passive) is carried out. (thieme-connect.de)
  • Both the chronic filarial patients and the asymptomatic microfilaria carriers showed statistically significant reduced suppression indices when compared with the control subjects. (karger.com)
  • The precore stop-codon mutation at nt position 1896 was found in 14/51 (27%) of HBeAg-negative samples, which is a lower prevalence rate in comparison with other parts of the world with high carrier rates. (ox.ac.uk)
  • And those who found out that they were a mutation carrier, they had actual things to do. (cdc.gov)
  • To test the hypothesis that young adults are more vulnerable to chronic sleep loss than older adults, we compared data from young and older adults who underwent three weeks of chronic sleep restriction (equivalent to 5.6 hours/24 hours) combined with recurrent circadian disruption in an experiment that enabled us to separate the influences of the sleep-wake homeostatic process, the circadian timing system, and the chronic sleep deficit. (nature.com)
  • Others develop a more chronic course with persistent or intermittent infectious mononucleosis-like symptoms including fever, persistent lymphadenopathy, splenomegaly, and EBV hepatitis. (frontiersin.org)
  • These reported symptoms were consistant with exposure to several volatile solvents and carriers in the vinyl fabric processed. (cdc.gov)
  • Four of 12 former workers reported the development of chronic respiratory symptoms during their employment. (cdc.gov)
  • My husband and I are both carriers of the DF508 gene. (healingwell.com)
  • and with advancments in the CF field they may even have a way to void the carrier gene before the baby is even born. (healingwell.com)
  • These include the hepatitis B and hepatitis C viruses, which can lead to chronic infections and liver cancer and claim more than a million lives each year. (pasteur.fr)
  • Hepatitis viruses constitute a major public health problem because of the morbidity and mortality associated with the acute and chronic consequences of these infections. (cdc.gov)
  • To compare parasitism and inflammatory process in esophagus and colon from chronic chagasic patients, immunohistochemistry was carried out to research for T. cruzi and to evaluate the inflammatory infiltrate in the muscular and myenteric plexus in 39 esophagi (20 with and 19 without megaesophagus) and 50 colons (25 with and 25 without megacolon). (hindawi.com)
  • The aim of this study was to evaluate comparatively the inflammatory process in muscular and myenteric plexus of esophagus and colon from chronic chagasic patients with and without mega, with the purpose of ascertaining whether there are similarities between the process in esophagus and colon and between cases with and without evident parasitism in the organ. (hindawi.com)
  • We studied 50 segments of large intestine and 39 segments of esophagus from chronic chagasic patients obtained by surgery (16 colon and 4 esophagus) or autopsies performed at the Department of Surgical Pathology/Special Pathology from the Hospital of Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, MG, Brazil. (hindawi.com)
  • A recent study showed that patients with CAEBV or infectious mononucleosis have a decrease in the TCR-beta repertoire and expanded T cell clones in their peripheral blood compared with healthy carriers of EBV ( 14 ). (frontiersin.org)
  • The reduction in suppression indices was greater in the microfilaria carriers than in the chronic filarial patients. (karger.com)
  • We confirmed, in the serum, increased miR-122 expression in HBV-infected patients and its highest expression in chronic HBV carriers, based on such comparison between the healthy controls and patients. (hindawi.com)
  • Additionally, the mean u-ACR levels were lower among carriers of the A/- or A/A genotypes with coexisting hypertension or diabetes, than among those with the −/− genotype. (lu.se)
  • Our aim with this study was to examine the ethical context of multidrug-resistant organism carriage: what are the negative implications for carriers, and what is the ethical relevance? (cdc.gov)
  • One hundred forty-two precore/core sequences were obtained from Gambian chronic hepatitis B virus (HBV) carriers and the predominant variants defined. (ox.ac.uk)
  • The newer carriers make it easier for severe allergy sufferers to enjoy a more normal way of life. (blogspot.com)
  • Many countries have implemented infection control measures directed at carriers of multidrug-resistant organisms. (cdc.gov)
  • The term "carriers" was initially used to identify people found to have the hepatitis B virus in their bloodstream for six months. (hepatitisaustralia.com)
  • This led to many people being told by doctors that they were "just healthy carriers" and that they needed no follow up. (hepatitisaustralia.com)
  • People who describe themselves as healthy carriers may feel they are less likely to experience stigma and discrimination 4 than those who say they have chronic hepatitis B virus. (hepatitisaustralia.com)
  • Screening is important for all people who have hepatitis B. One study found that more than one-third of people with chronic hepatitis B lived much longer if they had six-monthly screening, compared to no screening 6 . (hepatitisaustralia.com)
  • Chronic HBV carriers can be defined as those people in the immune tolerance phase who are positive for HBsAg, HBeAg, and HBV DNA and have normal liver function and no obvious abnormalities in the liver histology, and this situation might be maintained for several years or even decades [ 4 , 5 ]. (hindawi.com)
  • Such people are called carriers. (msdmanuals.com)
  • If you've been told that you are "just a healthy carrier", read on for a myth-busting update. (hepatitisaustralia.com)
  • Where did the term "healthy carrier" come from? (hepatitisaustralia.com)
  • Using the term "healthy carriers" might falsely imply that there are additional ways of passing on the virus as well as the usual transmission routes, or that healthy carriers are unlikely to transmit the infection to others. (hepatitisaustralia.com)
  • We found that control measures aimed at carriers have a range of negative implications. (cdc.gov)
  • Many individuals with HbSS experience chronic low-level pain, mainly in bones and joints. (medscape.com)
  • The functional characteristics of polysaccharide -based delivery carriers, such as pH responsiveness, mucosal adhesion, and further functionalization modifications, enhance the gastrointestinal absorption and bioavailability of insulin . (bvsalud.org)
  • Number of chronic carriers in the population (sheep that survive infection and continue to infect others). (alberta.ca)
  • Data was population, are chronic carriers [ 1-4 ]. (who.int)
  • All placebo-treated carriers still had positive cultures immediately after therapy. (edu.pe)
  • The hepatitis B virus (HBV) is one of the The subjects of this study were all house- most common chronic pathogens in the hold contacts of confirmed HBV chronic world. (who.int)
  • Results: Influenza A/Jerusalem 17/98 (H 1 N 1 ) was isolated from the throat of a chronic hepatitis C carrier who, presented with shortness of breath, and subsequent massive bilateral pneumonia. (bgu.ac.il)
  • NGS enables rapid carrier screening research across the broadest range of disorders, crossing ancestries and geographic regions, with a scalable, cost-effective solution. (thermofisher.com)