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  • trisomy
  • These changes include an extra copy of part of chromosome 7 in each cell (partial trisomy 7) or a missing segment of the chromosome in each cell (partial monosomy 7). (wikipedia.org)
  • We have identified distinct gene expression profiles and deregulated gene pathways in patients with del(5q), trisomy 8 or -7/del(7q). (ox.ac.uk)
  • Patients with trisomy 8 are characterized by deregulation of pathways involved in the immune response, patients with -7/del(7q) by pathways involved in cell survival, whereas patients with del(5q) show deregulation of integrin signaling and cell cycle regulation pathways. (ox.ac.uk)
  • Trisomy 7 in nonneoplastic cells. (naver.com)
  • cytogenetic
  • Twenty to forty percent of people with CMML have chromosomes that are abnormal in structure or number (called cytogenetic abnormalities). (lls.org)
  • POLD1 is also known as CDC2, MDPL, POLD, and CRCS10), is ~34 kb long and its cytogenetic location is chromosome 19 q13.33. (wikipedia.org)
  • UniGene
  • The human expression profile from NCBI UniGene suggests that this gene has widespread expression in many different tissues in the body. (wikipedia.org)
  • receptor
  • Human chorionic gonadotropin interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. (wikipedia.org)
  • cells
  • Following its purification from various sources including calf thymus, human placenta, and HeLa cells, its activity was implicated in DNA repair. (wikipedia.org)
  • Assays
  • We then performed quantitative real-time PCR analyses with 6 unique PCR assays to investigate 4 imprinting control regions on chromosomes 7 and 11 in individuals with uniparental disomy of chromosome 7 (UPD7) and in control individuals. (ox.ac.uk)
  • Translocation
  • About 1 to 4 percent of CMML patients have an abnormality called a "translocation" (a piece of one chromosome breaks off and attaches to another chromosome, which can lead to the development of an "oncogene" (cancer-causing gene). (lls.org)