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  • linkage
  • Nonparametric analysis of chromosome 12 inheritance data collected with the MODY3-linked markers D12S349 and D12S86 provides evidence for linkage to NIDDM with P values of 0.04 and 0.006, respectively, in Caucasian sib pairs using similar analyses. (diabetesjournals.org)
  • No evidence for linkage of MODY1 and MODY3 markers to NIDDM in African-American sib pairs was observed. (diabetesjournals.org)
  • A maximum LOD score of 1.48 was calculated for linkage to MODYl-linked loci and 1.45 to MODY3-linked loci in Caucasian sib pairs. (diabetesjournals.org)
  • recombination
  • Recombination events were identified that narrow the PPCD1-disease interval from 20 to 16.44 cM. (nih.gov)
  • markers
  • Haplotype analysis was performed using highly informative markers on the pericentromeric region of chromosome 20. (nih.gov)
  • If two given DNA markers are far apart on the initial chromosome, then it is likely that they will appear in distinct fragments. (wikipedia.org)
  • citation
  • citation needed] All but about one in three thousand of the rare calico or tortoiseshell male cats are sterile because of the chromosome abnormality, and breeders reject any exceptions for stud purposes because they generally are of poor physical quality and fertility. (wikipedia.org)
  • Exons
  • C7orf43 encodes 2 isoforms, the longest being C7orf43 isoform 1, which is 2585 base pairs long and has with 11 exons and 10 introns. (wikipedia.org)
  • In oxen, the coding sequence consists of 17 exons and has a length of about 34,500 nucleotide pairs. (wikipedia.org)
  • The gene is composed of 37 gt-at introns/alternative introns with 57 exons expressed in 1 unspliced form of 4253 bp and 20 alternatively spliced forms of varying lengths. (wikipedia.org)
  • simultaneously
  • Simultaneously, Mary F. Lyon began investigating manipulations of X-linked traits that had phenotypically visible consequences, particularly in mice, whose fur color is a trait intimately linked to the X chromosome. (wikipedia.org)
  • Klinefelter
  • Among humans, some men have two Xs and a Y ("XXY", see Klinefelter syndrome), or one X and two Ys (see XYY syndrome), and some women have three Xs or a single X instead of a double X ("X0", see Turner syndrome). (wikipedia.org)
  • different
  • A frequent question asked of creationists is, "Where did the different human races come from? (creation.com)
  • To identify different mRNA classes transcribed from the VSX1 gene, a 3′RACE experiment was performed on human adult retinal total RNA. (nih.gov)
  • Human accelerated regions (HARs), first described in August 2006, are a set of 49 segments of the human genome that are conserved throughout vertebrate evolution but are strikingly different in humans. (wikipedia.org)
  • single gene
  • Autosomal traits are associated with a single gene on an autosome (non-sex chromosome)-they are called "dominant" because a single copy-inherited from either parent-is enough to cause this trait to appear. (wikipedia.org)
  • A single gene (SRY) present on the Y chromosome acts as a signal to set the developmental pathway towards maleness. (wikipedia.org)
  • researchers
  • Scientific American, May 2009 Scientists Identify Gene Difference Between Humans and Chimps, Scientific American, 17 August 2006 Researchers Identify Human DNA on the Fast Track, Howard Hughes Medical Institute website, 16 August 2006. (wikipedia.org)
  • Male
  • Chromosome 20 pair in human male karyogram . (wikipedia.org)
  • This comes about because of the fertilization of the female egg (with its 23 chromosomes, one of which is an X) with a sperm from the male (with its 23 chromosomes, one of which is either an X or a Y). (brighthub.com)
  • Such a combination of chromosomes could produce tortoiseshell or calico markings in the male, in the same way as XX chromosomes produce them in the female. (wikipedia.org)
  • In any event, because the genetic conditions for calico coloring are X linked, a fertile male calico's coloring would not have any determination in the coloring of any male offspring (who would receive the Y, not the X chromosome from their father). (wikipedia.org)
  • There are other exceptions in which SRY is damaged (leading to an XY female), or copied to the X (leading to an XX male). (wikipedia.org)
  • Offspring have two sex chromosomes: an offspring with two X chromosomes will develop female characteristics, and an offspring with an X and a Y chromosome will develop male characteristics. (wikipedia.org)