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  • breakpoints
  • We and others have found that the breakpoints on chromosome 14, with one exception, fall within the switch region upstream of the immunoglobulin heavy chain C alpha 1 or C alpha 2 sequences. (nih.gov)
  • For example, RD does not depend on paired reads for finding SVs and is able to detect CNVs with mutated or rough breakpoints that may not be detectable with paired or split reads, but RD is unable to detect insertions, translocations, and inversions. (peerj.com)
  • cats
  • Although the term 'therapy cats' might sound like the name of some contemporary jazz band, in fact, it describes a group of animals that can have the same positive effects on humans that music can, and so much more besides. (kittywise.com)
  • In this article, we are going to define what a therapy cat is, the ways in which therapy cats can help humans, and what it takes for a cat to be regarded as suitable to be a therapy cat. (kittywise.com)
  • It's been long known by veterinarians that cats and humans are afflicted with similar diseases, such as some cancers and immunodeficiency viruses such as HIV, which is similar to the feline immunodeficiency virus, or FIV. (courant.com)
  • This discovery has led researchers to explore how certain diseases affect humans and cats. (courant.com)
  • African and North American cat species (and domestic cats, which originated from African Wildcats, Felis silvestris ), have 19 different kinds of chromosomes, with 2 of each kind (having 2 sets of chromosomes is referred to as 'diploid' by biologists). (sweetspotssavannahs.com)
  • In contrast to humans, most cats have 38 chromosomes (19 pairs). (everydayknow.com)
  • The cats that have 36 chromosomes are those in the Ocelot lineage. (everydayknow.com)
  • Cloning
  • Kekuda R, Prasad PD, Fei YJ, Torres-Zamorano V, Sinha S, Yang-Feng TL,Leibach FH, Ganapathy V. Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bofrom a human placental choriocarcinoma cell line.J Biol Chem. (tcdb.org)
  • In the present paper, we describe three additional patients with the t(14;19), one with lymphoma and two with CLL, and report the cloning and sequencing of the breakpoint junction in one of these patients as well as in a previously reported patient. (nih.gov)
  • diseases
  • This challenge is not based on faithfulness, courage or schmoozing with their owners, but on genetic links that may help in finding cures for some human diseases. (courant.com)
  • Genetic research may turn more to animals' natural genetic adaptations that they have acquired, which has allowed them to overcome some of the diseases now incurable in humans. (courant.com)
  • All they had was natural selection, so each surviving species has generated genetic adaptations allowing them to fight off some of the diseases humans are starting to see. (courant.com)
  • The immune system is considered to be tightly regulated by the balance between the activating and inhibitory signals through these paired receptors, and dysregulation of this balance often causes autoimmunity, allergy, and various infectious diseases. (frontiersin.org)
  • gene pairs
  • They then measured for each of the gene pairs synonymous nucleotide divergence-silent changes in the nucleotide sequence. (mit.edu)
  • Because they are therefore selectively neutral, synonymous substitutions serve as a molecular clock, providing a measure of the evolutionary time that has elapsed since the gene pairs began to differentiate. (mit.edu)
  • They wanted a dog with the most "homzygosity"- the least variation between maternal/paternal gene pairs. (massapequapost.com)
  • Cells
  • We have isolated a cDNA from a human placental choriocarcinoma cell cDNA library which, when expressed in HeLa cells, induces a Na+-dependent amino acid transport system with preference for zwitterionic amino acids. (tcdb.org)
  • During the formation of these reproductive cells, each cell gets only one copy of each chromosome. (lifelearn-cliented.com)
  • This will result in the offspring's cells again having paired sets of chromosomes, with two copies of each gene. (lifelearn-cliented.com)
  • The t(14;19)(q32.3;q13.1) is a recurring translocation found in the neoplastic cells of some patients with chronic lymphocytic leukemia (CLL) or other B-lymphocytic neoplasms. (nih.gov)
  • Evolution
  • Evidence for co-evolution between human microRNAs and Alu-repeats. (nih.gov)
  • In a study published in Friday's issue of Science, Dr. Page and Bruce Lahn, then a postdoctoral fellow at the Whitehead Institute, report that they have reconstructed the stages of sex chromosome evolution and the time course over which these chromosomes were built. (mit.edu)
  • subset
  • Base-pair complementarity could be demonstrated between the seed sequence of a subset of human microRNAs and Alu repeats that are integrated parallel (sense) in mRNAs. (nih.gov)
  • region
  • Haplotype data of six polymorphic markers in the DM gene region indicate that, in this latter case, two stretches of the affected chromosome had been exchanged with that region of the wild-type chromosome. (biomedsearch.com)
  • long
  • The rationale behind this arrangement has long perplexed scientists like David Page, a member of the Whitehead Institute and an expert on the Y chromosome, who wonder how these unique chromosomes first came about. (mit.edu)
  • therapy
  • The definition of a therapy cat is a cat which has been deemed suitable to interact with humans in such a way that it provides medical benefits. (kittywise.com)
  • scientists
  • Research done on the feline leukemia virus has already taught scientists more about how some cancers develop in humans. (courant.com)
  • several
  • Several of the breaks within chromosome 19 fall immediately upstream of the BCL3 gene, but several others are more than 16 kb 5' of the gene. (nih.gov)
  • In this review, we introduce several representative examples of paired receptors, focusing on two major structural superfamilies, the immunoglobulin-like and the C-type lectin-like receptors, and explain how these receptors distinguish self and non-self ligands to maintain homeostasis in the immune system. (frontiersin.org)
  • means
  • This research provides a glimpse back in time and a means to understand how sex chromosomes-one of nature's greatest experiments-first emerged. (mit.edu)