• BCL10 nuclear expression was observed in 7 of 8 t(11;18)(q21;q21)-positive cases and 4 of 7 t(11;18)(q21;q21)-negative cases, including one case suspicious for a BCL10-involved chromosomal translocation. (biomedsearch.com)
  • A genomic analysis indicated that NPC1-MELK arose from a complex interchromosomal translocation event involving chromosomes 18, 3, and 9 with 3 rearrangement points, and this was consistent with chromoplexy. (elsevier.com)
  • Expression of the bcl-2 oncogene product and chromosomal translocation t(14;18) in Hodgkin's disease. (ox.ac.uk)
  • The reciprocal chromosomal translocation t(14;18), leading to overexpression of this oncogene, can be found in the majority of follicular lymphomas and much less frequently in B-cell leukemias and diffuse lymphomas. (ox.ac.uk)
  • We have studied the expression of this protein in different subtypes of Hodgkin's disease using monoclonal antibodies directed against a formalin-resistant epitope of the bcl-2 protein and also have investigated these cases by polymerase chain reaction for evidence of the t(14;18) translocation. (ox.ac.uk)
  • In a smaller number of cases this expression of bcl-2 could be explained by the presence of the translocation t(14;18). (ox.ac.uk)
  • The translocation t(11;18)(q21;q21) characteristic of MALT lymphoma is recognized as a marker for H. pylori independency, but this marker is found in only a half of the MALT lymphomas resistant to H. pylori eradication. (nih.gov)
  • Mehrabi, R, Taga, M & Kema, GHJ 2007, ' Electrophoretic and cytological karyotyping of the foliar wheat pathogen Mycosphaerella graminicola reveals many chromosomes with a large size range ', Mycologia , vol. 99, no. 6, pp. 868-876. (elsevier.com)
  • Definitive diagnosis is achieved through karyotyping, which involves drawing the baby's blood for a microscopic examination of the chromosomes. (healthofchildren.com)
  • High incidence of t(11;18)(q21;q21) in Helicobacter pylori-negative gastric MALT lymphoma. (biomedsearch.com)
  • Chromosomal imbalances are associated with outcome of Helicobacter pylori eradication in t(11;18)(q21;q21) negative gastric mucosa-associated lymph. (nih.gov)
  • Chromosomal imbalances are associated with outcome of Helicobacter pylori eradication in t(11;18)(q21;q21) negative gastric mucosa-associated lymphoid tissue lymphomas. (nih.gov)
  • Ninety-five percent of the children are full trisomies, 2 percent are due to translocations, where only part of an extra chromosome is present (this may be hereditary), while 3 percent are mosaic trisomies, where the extra chromosome is present in some but not all of the cells. (healthofchildren.com)
  • To assess the performance of screening for fetal trisomies 21, 18 and 13 by cell-free (cf) DNA analysis of maternal blood using a new method based on paired-end massively parallel shotgun sequencing (MPSS). (unboundmedicine.com)
  • This was a blinded study of plasma samples (1mL) obtained from 1000 women undergoing screening for fetal trisomies 21, 18 and 13 at 11-13 weeks' gestation. (unboundmedicine.com)
  • Each sample was classified as trisomic or unaffected using chromosome-specific cut-offs set at t-score values of 1.5 for trisomy 21 and 3.0 for trisomies 18 and 13. (unboundmedicine.com)
  • These cytokine response changes were consistent with those seen in S. aureus-challenged peritoneal macrophages from CSS 18 mice (which contain A/J chromosome 18 but are otherwise C57BL/6J), but not C57BL/6J mice. (elsevier.com)
  • We reviewed the clinical data and histology, and we examined t(11;18)(q21;q21) and BCL10 expression pattern in 17 such cases. (biomedsearch.com)
  • rs4331426, located in a gene-poor region on chromosome 18q11.2, was associated with disease (combined P = 6.8 x 10(-9), odds ratio = 1.19, 95% CI = 1.13-1.27). (ox.ac.uk)
  • Reverse transcription-polymerase chain reaction (RT-PCR) showed t(11;18)(q21;q21) in 9 (53%) of 17 cases, more frequent in lymphomas at stage II(E) or above (5 of 6) than those at stage I(E) (3 of 10). (biomedsearch.com)
  • Two t(11;18)(q21;q21)-positive lymphomas were treated by partial gastrectomy and more than 16 years later showed lymphoma relapse in the gastric stump with dissemination to other mucosal sites, poorly responsive to therapy. (biomedsearch.com)
  • Our results show that t(11;18)(q21;q21) occurs at a high frequency in H pylori-negative gastric MALT lymphomas. (biomedsearch.com)
  • Genomic imbalances are associated with H. pylori independency in t(11;18) negative gastric MALT lymphomas. (nih.gov)
  • These comprised ten cases of t(11;18) positive MALT, nine cases of t(11;18) negative MALT with H. pylori dependency, and ten cases of t(11;18) negative MALT with H. pylori independency. (nih.gov)
  • Within the t(11;18) negative MALT lymphoma without large cell components group, genomic imbalances occurred more frequently in the H. pylori independent than in the H. pylori dependent group (P = 0.02). (nih.gov)
  • Paired-end MPSS with the neoBona® test allowed simultaneous assessment of fetal fraction, cfDNA fragment size distribution and chromosome counting, which were integrated into a new analysis algorithm to calculate trisomy likelihood ratios (t-score) for each chromosome of interest. (unboundmedicine.com)