Loading...
  • 2001
  • Alonso, S, Armour, JA 2001 A highly variable segment of human subterminal 16p reveals a history of population growth for modern humans outside Africa. (springer.com)
  • 1991
  • Badcock, C 1991 Evolution and individual behavior: An introduction to human sociobiology. (springer.com)
  • 1995
  • Bertorelle, G, Slatkin, M 1995 The number of segregating sites in expanding human populations, with implications for estimates of demographic parameters. (springer.com)
  • mutation
  • In this paper, we show that mismatch distributions and tests of mutation/drift equilibrium based on up to 166 Y-chromosome SNPs, in 46 samples from all continents, also fail to support an increase of the male effective population size. (springer.com)
  • These unique properties of the Y have important consequences for its mutation processes, its genes, and its population genetics: Y chromosomes pass down from father to son largely unchanged, except by the gradual accumulation of mutations. (le.ac.uk)
  • mutation analysis at MSY1 provides a tool which should allow us to estimate ages for the most recent common ancestors of groups of chromosomes, as an alternative to microsatellites (7). (le.ac.uk)
  • mice
  • RODENTS and people may not appear to be closely related, but consider this the next time you look in a mirror: the genes of human beings and mice are 85 percent identical. (llnl.gov)
  • The Mta3 is localized on chromosome 12p in mice and MTA3 on 2p21 in human. (wikipedia.org)
  • region
  • Three region-specific libraries for the entire human chromosome 18 were constructed using microdissection and MboI linker-adaptor microcloning techniques. (springer.com)
  • Clinical
  • Nonhuman antibodies from, for instance, birds and primates, have been safely administered to people in the past, so human antibodies are expected to prove safe in phase 1 clinical trials, says reproductive physiologist Eddie Sullivan of SAB Biotherapeutics, who headed the project to develop the transchromosomal cows. (sciencemag.org)
  • In order to really finish the proof-of-concept, clinical studies in humans showing safety need to be performed," Hooper says. (sciencemag.org)
  • populations
  • Evidence of prehistoric demographic expansions has been detected in the mitochondrial diversity of most human populations and in a Y-chromosome STR analysis, but not in a previous study of 11 Y-chromosome SNPs in Europeans. (springer.com)
  • We have coordinated a large collaborative study to test hypotheses for the origins of modern European populations from a Y chromosome perspective (9, 10), interpreting patterns of diversity in terms of both the impact of the arrival of agriculture in Europe, and of linguistic and geographical barriers to gene flow. (le.ac.uk)
  • mutant
  • They label a gene from a normal chromosome 2 with the fluorescent dye and add it to a slide containing the mutant mouse chromosomes. (llnl.gov)
  • A heat-sensitive (hs) leucyl-tRNA synthetase (leuRS) deficient CHO mutant, ts025Cl, was fused with human leukocytes and hybrids isolated in HAT medium at the nonpermissive temperature. (springer.com)