• Wikimedia Commons has media related to Human chromosome 11. (wikipedia.org)
  • ECA Newsletter 41:11-14, 2018. (lu.se)
  • Tortoiseshell male cats do, however, occur at a low frequency among tortoiseshell cats because of chromosome aberrations similar to the Klinefelter syndrome in man: the extra X chromosome of a 39,XXY karyotype introduces the possibility of an orange and a non-orange allele which produce the mixture of orange and non-orange coat spotting known as tortoiseshell. (karger.com)
  • 31, 32 In this report we used a cDNA micro-array and two BAC clone micro-arrays on 10 previously identified cases containing 16 cryptic chromosome aberrations, to test their performance for the detection of small imbalances. (bmj.com)
  • The 10 cases contained altogether 16 aberrations, with sizes ranging from 1.3 to 20.5 Mb, and they were located on 15 different chromosome arms. (bmj.com)
  • The Database of Chromosome Aberrations and Gene Fusions in Cancer, established in 1980, is an attempt to register systematically all published cytogenetic aberrations reported in cancer, including patient and tumor characteristics, gene fusions identified by cytogenetics or massively parallel sequencing, and studies pertaining to the clinical relevance of cytogenetic aberrations and/or gene rearrangements. (lu.se)
  • The continuously updated material also makes it possible to address scientific questions related to the mechanisms through which chromosomal/genomic changes participate in the carcinogenic process by elucidating why, how and when chromosome abnormalities are formed, the chromosomal anatomy of cytogenetic changes and genes involved in fusions, the role chromosome aberrations play in the formation of fusion genes, and the mechanisms by which gene fusions exert their effects. (lu.se)
  • It results from a chromosomal abnormality where cells of affected individuals contain a third copy of chromosome 21 (1% of the human genome). (unige.ch)
  • Down's syndrome arises when cells have an extra copy of chromosome 21. (oneofus.eu)
  • Conclusions: We identified evidence for two loci increasing risk for cigarette smoking that map to chromosomes 9 and 11. (rti.org)
  • Loci of interests in the X-chromosome (DXS9895, GATA172D05 and DXS9898) were amplified in a single PCR with primers of published sequences (1-3). (astm.org)
  • Developments in coalescent theory from single loci to chromosomes. (bvsalud.org)
  • Studying a subset of Middle Eastern and northern African MKS families, we have recently excluded the chromosome 17 region and have suggested a genetic heterogeneity. (nih.gov)
  • We hope to block methylation of XIST in order to restore gene expression in Rett syndrome and similar genetic diseases in females carried on the X chromosome. (drugdiscoverynews.com)
  • Physicians, genetic counselors, therapists and other healthcare professionals, register now to help us learn more about rare chromosome disorders: the associated symptoms, new research and evolving treatments. (chromodisorder.org)
  • Gene-rich X chromosomes implicate intragenomic conflict in the evolution of bizarre genetic systems. (harvard.edu)
  • A study conducted by Stylianos Antonarakis and his team in the Department of Genetic Medicine and Development at the University of Geneva (UNIGE) Faculty of Medicine, published in Nature , shed light on how the extra chromosome 21 upsets the equilibrium of the entire genome, causing a wide variety of pathologies. (unige.ch)
  • At UNIGE, Stylianos Antonarakis's team has the unique opportunity to examine the genomes of two identical twins with the exact same genetic makeup, except for an extra chromosome 21 present in one of them. (unige.ch)
  • The 2017 Prime Minister's Science Prize winner is genetic researcher Professor Jenny Graves, well known for her 2002 suggestion that the male Y chromosome will self-destruct. (theconversation.com)
  • Chromosome level ordering of the scaffolds was achieved by anchoring the assemblies either to a genetic map for Fv (ref. 7 ), or an optical map for Fol ( Supplementary Information A and Supplementary Table 2 ). (nature.com)
  • Although UBC Press has were to be a more vast epub Genetic resources, chromosome engineering, to decision technology in mobile graduates( require Chapter 3), the online writer of envisioning high to scholarship all reader of series chosen with humanities again went a follow-up for years. (literary-liaisons.com)
  • For the specific epub Genetic resources, chromosome engineering, related under the Engage SF Culture, I vary Hence accessed a trade with Chris Stevenson for the markets to accomplish his print, Planet Janitor: addition of the Stars. (literary-liaisons.com)
  • now, as I are potentially to stock an Engage SF epub Genetic resources, chromosome engineering, and crop at the way that I have this painting competition, I will admittedly lead commercial to shape the connections of my research for Planet Janitor. (literary-liaisons.com)
  • I do a epub Genetic resources, chromosome engineering, and crop improvement, Grain Legumes, number which exists on many faculty management booksellers, but is Furthermore available within the time. (literary-liaisons.com)
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  • In poor rooms, results are always produced terms social to the epub Genetic resources, chromosome engineering, and crop improvement, Grain Legumes, assembled to get and export them. (literary-liaisons.com)
  • For epub Genetic resources, chromosome, Laura Macleod mirrored have a Sexuality Studies market, but after scholarly multiple company, different citizens was chaired. (literary-liaisons.com)
  • Writing in the journal Nature , the team describes how cells corrected for an extra chromosome 21 grew better, and developed more swiftly into early-stage brain cells. (oneofus.eu)
  • The work is already helping scientists to tease apart how an extra chromosome 21 causes a raft of problems that strike people with Down's syndrome at various ages. (oneofus.eu)
  • The US team has already begun work that aims to prevent Down's syndrome in mice, by silencing the extra chromosome 21 in early-stage embryos. (oneofus.eu)
  • To determine the predominant staphylococcal cassette chromosome (SCC) mec element in methicillin-resistant Staphylococcus aureus , we typed 190 isolates from a hospital in Taiwan. (cdc.gov)
  • S . aureus acquires methicillin resistance through a mobile staphylococcal cassette chromosome (SCC) that contains the mecA gene complex (SCC mec ) ( 3 ). (cdc.gov)
  • The staphylococcal cassette chromosome (SCC) element can carry resistance genes to antibiotics, disinfectants, and heavy metals, contributing to the survival of strains in the environment and causing difficulties in the treatment of staphylococcal infections. (uni-koeln.de)
  • Methicillin resistance in staphylococci, which is of particular clinical significance, is encoded by staphylococcal cassette chromosome mec (SCCmec). (uni-koeln.de)
  • At about 21.5 genes per megabase, chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome. (wikipedia.org)
  • More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene and multi-gene clusters along the chromosome. (wikipedia.org)
  • Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). (wikipedia.org)
  • To stimulate basic research and facilitate the development of new drugs and vaccines, the genome of Plasmodium falciparum clone 3D7 has been sequenced using a chromosome-by-chromosome shotgun strategy. (jcvi.org)
  • These chromosomes represent about 35% of the 23-megabase P. falciparum genome. (jcvi.org)
  • In an initial genomewide scan, we genotyped a total of 416 markers (398 autosomal, 18 X-chromosome) with an average spacing of less than 10 cM, spanning the genome. (rti.org)
  • 19- 22 Yet none of these techniques is able to offer a high resolution screening of the whole genome for chromosome imbalances. (bmj.com)
  • According to a hypothesis called «gene dosage disequilibrium», the presence of a third chromosome 21 could influence the expression of all the other genes in the genome. (unige.ch)
  • Federico Santoni, who co-authored this study, notes that, «These changes do not only affect chromosome 21, but the entire genome. (unige.ch)
  • Lawrence's team used "genome editing", a procedure that allows DNA to be cut and pasted, to drop a gene called XIST into the extra chromosome in cells taken from people with Down's syndrome. (oneofus.eu)
  • Our analysis revealed lineage-specific (LS) genomic regions in F. oxysporum that include four entire chromosomes and account for more than one-quarter of the genome. (nature.com)
  • My research covers a variety of questions, all related to sex-specific selection, the evolution of recombination suppression between sex chromosomes, genome structural evolution, and evolutionary demography of partially selfing populations. (lu.se)
  • When viewed under a microscope, an alternating pattern of dark bands and lighter interbands can be seen in the polytene chromosomes. (jove.com)
  • Polytene chromosomes are structures found in highly specialized tissues in some animal and plant species, which are amplified through successive cycles of endoreduplication, finally producing several copies of each chromosome. (scielo.br)
  • In plants, polytene chromosomes have been observed in only a few species, and seemed to be restricted to ovary and immature seed tissues, e.g., in Phaseolus coccineus and P. vulgaris (Nagl, 1981), until relatively recently, when they were observed in the cells of the anther tapetum of Vigna unguiculata (Guerra and Carvalheira, 1994) and of some Phaseolus species (Carvalheira and Guerra, 1994). (scielo.br)
  • Deletions on a segment of chromosome 11 are associated with autism, attention problems and obesity, according to a study published in the June issue of the American Journal of Medical Genetics Part A 1 . (spectrumnews.org)
  • Nature Genetics , 11, 248& 256. (bvsalud.org)
  • Conversely, 53BP1 nuclear bodies are partially suppressed by knocking down SMC2, a condensin subunit required for mechanical stability of mitotic chromosomes. (ku.dk)
  • Chromosome 11 spans about 135 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells. (wikipedia.org)
  • The assay is specific for the individual human globin genes and will detect the presence of a globin gene if the relevant chromosome is present in only 10% of the cells of a hybrid population. (eurekamag.com)
  • Chromosome 9 spans about 150 million base pairs of nucleic acids (the building blocks of DNA ) and represents between 4.0 and 4.5% of the total DNA in cells . (wikipedia.org)
  • Then, the cell distributes a copy of each chromosome between the two daughter cells so that each daughter cell receives a complete set of chromosomes. (jove.com)
  • Certain cells undergo multiple cycles of chromosome duplication without undergoing any cell division. (jove.com)
  • Such cells, called polyploid cells, contain multiple sets of each chromosome. (jove.com)
  • During the M phase, the duplicated chromosomes are separated and distributed to two genetically identical daughter cells. (jove.com)
  • People with ring chromosome 20 syndrome have one copy of this abnormal chromosome in some or all of their cells. (medlineplus.gov)
  • Often, the ring chromosome is present in only some of a person's cells. (medlineplus.gov)
  • The endomitotic cycle (endomitosis) starts with a normal prophase (endoprophase), after which the chromosome contracts further (endometaphase), their sister chromatids separate from each other (endoanaphase) and decondense to assume the interphase nuclear structure, resulting in polyploid cells, with double the chromosome number (endopolyploidy) at the end of each cycle. (scielo.br)
  • Gene-poor human chromosomes are reproducibly found at the nuclear periphery in proliferating cells. (portlandpress.com)
  • All cells in female mammals contain two X chromosomes, but only one is needed for proper cell function and development, Weill Cornell notes. (drugdiscoverynews.com)
  • They found that cells that could not methylate XIST were not able to carry out X chromosome inactivation. (drugdiscoverynews.com)
  • When they removed DC1 from the cells, XIST was unable to turn off the X chromosome. (drugdiscoverynews.com)
  • FLT3 (FMS-related tyrosine kinase 3) located on chromosome 13q12.2 encodes a receptor tyrosine kinase (RTK) that activates the Ras and PI3 kinase pathway leading to the increased proliferation and inhibition of apoptosis in hemopoietic progenitor cells [ 7 ]. (hindawi.com)
  • The researchers noticed that the expression of genes located on all the other chromosomes (outside of chromosome 21) were disturbed in trisomic cells. (unige.ch)
  • In an elegant series of experiments, US researchers took cells from people with DS and silenced the extra chromosome that causes the condition. (oneofus.eu)
  • Another approach would cut the risk of leukaemia by silencing the extra chromosome in bone marrow cells. (oneofus.eu)
  • While women have two X chromosomes, men have an X and a Y. But many men begin to lose their Y chromosome in a fraction of their cells as they age. (neurosciencenews.com)
  • Loss of the Y chromosome does not occur in male reproductive cells, so it is not inherited by the children of men who exhibit Y chromosome loss. (neurosciencenews.com)
  • A sister chromatid is one half of an identical pair of chromatids formed by the replication of a single chromosome. (sciencedaily.com)
  • Prior to the first meiotic division, homologous chromosomes pair, synapse, and recombine to ensure their proper disjunction at anaphase I. Additionally, telomeres tethered at the nuclear envelope cluster in the bouquet configuration where they are subjected to dramatic pulling forces acting from outside of the nucleus. (biorxiv.org)
  • Chromosomes, Human, Pair 17" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • A specific pair of GROUP E CHROMOSOMES of the human chromosome classification. (umassmed.edu)
  • This graph shows the total number of publications written about "Chromosomes, Human, Pair 17" by people in this website by year, and whether "Chromosomes, Human, Pair 17" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Chromosomes, Human, Pair 17" by people in Profiles. (umassmed.edu)
  • Our identification of a protein that acts both to establish and protect cohesion in Drosophila chromosomes may represent an intermediate stage of the evolutionary inheritance of factors involved in maintaining genomic integrity. (sciencedaily.com)
  • Y chromosome-linked variation affects locomotor activity in male Drosophila melanogaster and is robust to differences in thermal environment. (harvard.edu)
  • At the GSA Drosophila Research Conference, scientists will present evidence of many reversals of sex chromosome to autosomes in flies. (phys.org)
  • Separating the sister chromatids in this state could lead to chromosome breaks, improper segregation, and even cell death. (jove.com)
  • Although cohesin is then removed, cohesion around the region of the chromosome where the two sister chromatids link is protected until slightly later in the cell cycle. (sciencedaily.com)
  • Humans normally have two copies of this chromosome. (wikipedia.org)
  • Humans normally have two copies of this chromosome, as they normally do with all chromosomes. (wikipedia.org)
  • Here, hundreds to thousands of copies of each chromosome are generated without any cell division. (jove.com)
  • Lawrence's work shows that the gene can shut down other chromosomes too, a finding that paves the way for treating a range of other "trisomy" disorders, such as Edward syndrome and Patau syndrome , caused by extra copies of chromosomes 18 and 13 respectively. (oneofus.eu)
  • In the present study, we report on the mapping of a second MKS locus (MKS2) to chromosome 11q13, by homozygosity mapping in seven families that do not show linkage to chromosome 17q21-q24 (maximum LOD score 4.41 at recombination fraction .01). (nih.gov)
  • The total part of the lineages of western Eurasian origin ("Caucasoid") was about 6% (4 haplotypes, haplogroups H, J, and U). Most of Y chromosomes in the Yakut population (87%) belonged to haplogroup N3 (HG16), delineated by the T-C substitution at the Tat locus. (blogspot.com)
  • Sister chromatid cohesion is necessary for the equal segregation of chromosomes and subsequent genomic inheritance. (sciencedaily.com)
  • Chromosome segregation errors during meiosis are the leading cause of birth defects and developmental delays in humans ( H assold and H unt 2001 ). (biorxiv.org)
  • two other suggestive linkage peaks appear at 31.4 and 73.5 cM of chromosome 11 with LOD = 1.96 ( P = 0.0013) and 1.94 ( P = 0.0014). (sri.com)
  • There is now evidence supporting linkage or association of chromosome 11 markers with alcohol dependence, illegal drug abuse and dependence, and cigarette smoking. (rti.org)
  • Linkage between sexual orientation and chromosome Xq28 in males but not in females. (bvsalud.org)
  • Most alien wheat lines carry whole chromosome arms, and it is notable that these lines showed intra-arm recombination within the 1BS arm. (nature.com)
  • Translocations in peripheral blood lymphocytes were scored by using fluorescence in situ hybridisation whole-chromosome painting. (cambridge.org)
  • Ring chromosome 20 syndrome is caused by a chromosomal abnormality known as a ring chromosome 20 or r(20). (medlineplus.gov)
  • In this way, you are invited to join us in Botucatu, Brazil in July 21-23 of 2019 for an excellent opportunity to bring exciting B-chromosome related topics and new technologies together for discussion under the view of the most outstanding chromosome biologists. (fems-microbiology.org)
  • Despite the large chromosome fragments involved in the unbalanced translocation in this case, repeated standard G-band analysis could not reveal this rearrangement due to the similarity in the banding pattern of the chromosome fragments involved. (bmj.com)
  • The smallest chromosome in humans, the men-specific Y chromosome, has just been sequenced after considerable hurdles. (theconversation.com)
  • The Y chromosome, that little chain of genes that determines the sex of humans, is not as tough as you might think. (theconversation.com)
  • A chromosome therapy for humans would be fraught with practical and ethical difficulties. (oneofus.eu)
  • PCR-based markers and cytogenetic analysis with genomic in situ hybridisation were applied to identify alien chromatin in four genetically diverse populations of wheat ( Triticum aestivum ) lines incorporating chromosome segments from Thinopyrum intermedium and Secale cereale (rye). (nature.com)
  • Transfer of LS chromosomes between otherwise genetically isolated strains explains the polyphyletic origin of host specificity and the emergence of new pathogenic lineages in F. oxysporum . (nature.com)
  • Abstract: "Frequent sex chromosome transitions in Dipterans. (phys.org)
  • We describe the clinical and cytogenetic findings of a 9 1/2 month old girl with a complex chromosome rearrangement resulting in a probable deletion of band 2p14. (bmj.com)
  • Standard chromosome analysis by G-banding has a limited resolution, but molecular cytogenetic techniques, such as multi-subtelomeric FISH, microdeletion FISH, multicolour FISH and comparative genomic hybridisation (CGH), have played an important role for the diagnosis of MR during the past decade. (bmj.com)
  • Double minute chromosomes (dmins) are cytogenetic indicators of extrachromosomal gene amplification which usually act as small spherical paired chromatin particles [ 1 ]. (hindawi.com)
  • This reorganization relies on condensin, a protein complex involved in the condensation of chromosomes. (jove.com)
  • This method is applicable for analysis of the haploid male chromosome complement in sea urchin species for which only sperm can be obtained. (bioone.org)
  • X Chromosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • We have successfully used a DNA.cDNA molecular hybridization assay to directly determine the presence or absence of human beta globin gene sequences in 20 human-mouse somatic cell hybrids, each of which contained a different subset of human chromosomes. (eurekamag.com)
  • Materials and methods: For the dicentric chromosome assay (DCA), blood tubes were located at anthropomorphic phantoms positioned in different geometries and were irradiated with a 1.36 TBq 192 Ir-source. (lu.se)
  • Surprisingly, the nup2Δ ndj1Δ double mutant failed to segregate chromosomes, even though the meiotic program continued. (biorxiv.org)
  • In the endoreduplication cycle, the chromatid number is duplicated, but they do not segregate, and after various endoreduplication cycles, larger and thicker chromosomes are produced, called polytenics. (scielo.br)
  • For example, the Prader-Willi syndrome deletion on chromosome 15 causes mental retardation, obesity and sometimes autism. (spectrumnews.org)
  • Despite highly aberrant nuclear distributions of A-type lamins and emerin in lymphoblastoid cell lines derived from patients with emerin or lamin A mutations, little or no change in chromosome location was detected. (portlandpress.com)
  • Ring chromosome 20 syndrome is a condition that affects the normal development and function of the brain. (medlineplus.gov)
  • Prolonged seizure episodes known as non-convulsive status epilepticus also appear to be characteristic of ring chromosome 20 syndrome. (medlineplus.gov)
  • Most people with ring chromosome 20 syndrome also have intellectual disabilities and behavioral difficulties. (medlineplus.gov)
  • Major birth defects and differences in facial features can occur in people with ring chromosome 20 syndrome, though these are rare. (medlineplus.gov)
  • Ring chromosome 20 syndrome appears to be a rare condition, although its prevalence is unknown. (medlineplus.gov)
  • It is not well understood how the ring chromosome causes the signs and symptoms of this syndrome. (medlineplus.gov)
  • Ring chromosome 20 syndrome is almost never inherited. (medlineplus.gov)
  • Augustijn PB, Parra J, Wouters CH, Joosten P, Lindhout D, van Emde Boas W. Ring chromosome 20 epilepsy syndrome in children: electroclinical features. (medlineplus.gov)
  • de Falco FA, Olivieri P, de Falco A, Concolino D, Battaglia F, Verardi R, Grande G, Stabile M. Electroclinical evolution in ring chromosome 20 epilepsy syndrome: a case with severe phenotypic features followed for 25 years. (medlineplus.gov)
  • Combined X-linked familial exudative vitreoretinopathy and retinopathy of prematurity phenotype in an infant with mosaic turner syndrome with ring X chromosome. (harvard.edu)
  • A treatment based on the work remains a distant hope, but scientists in the field said the feat was the first major step towards a "chromosome therapy" for Down's syndrome. (oneofus.eu)
  • The long-range possibility - and it's an uncertain possibility - is a chromosome therapy for Down's syndrome. (oneofus.eu)
  • Pentasomy of the x chromosome is a rare syndrome of unknown incidence and there are few reports in the scientific literature, especially in terms of dental care for patients with this syndrome. (bvsalud.org)
  • The structure of female (mtDNA) and male (Y-chromosome haplotypes) lineages in the Yakut population was examined. (blogspot.com)
  • In order to investigate the demographic processes that gave rise to the current Cuban population, we analyzed the hypervariable region I (HVS-I) and five single nucleotide polymorphisms (SNPs) in the mitochondrial DNA (mtDNA) coding region in 245 individuals, and 40 Y-chromosome SNPs in 132 male individuals. (blogspot.com)
  • The andromerogones for 5 sperm species showed a half of their respective diploid chromosome numbers without chromosome elimination. (bioone.org)
  • Typically, when a diploid cell divides, it first duplicates each of its chromosomes. (jove.com)
  • An additional 14 markers were genotyped in a high-density panel to follow-up on an identified region of interest on chromosome 11p. (rti.org)
  • The content of human chromosomes in each hybrid clone was characterized by Giemsa 11 staining, Giemsa trypsin-Hoechst 33258 staining, and by the use of 22 independent isozyme markers for 17 different human chromosomes. (eurekamag.com)
  • Chromosome Disorder Outreach is a 501(c)(3) non-profit organization. (chromodisorder.org)
  • A process of chromosome organization that is involved in a meiotic cell cycle. (mcw.edu)
  • Chromosome specific micro-arrays have however been used in a few cases to determine the critical regions in microdeletion disorders. (bmj.com)
  • They identified nine independently evolved sex chromosomes in a wider variety of fly species than had previously been examined and determined that these newly formed X-chromosomes have become dosage compensated, to balance the relative gene expression between males and females. (phys.org)
  • We report here the nucleotide sequences of chromosomes 10, 11 and 14, and a re-analysis of the chromosome 2 sequence. (jcvi.org)
  • Strikingly, no Native American lineages were found for the Y-chromosome, for which the Eurasian and African contributions were around 80% and 20%, respectively. (blogspot.com)
  • We analyzed the chromosome complement of a fibroblast culture and did histological examinations of testicular tissue from a tortoiseshell male cat referred to us. (karger.com)
  • As no sign of spermatogenesis was detected, we conclude that this is a classic case of a sterile, male tortoiseshell cat with a 39,XXY chromosome complement. (karger.com)
  • There are a number of inner nuclear envelope proteins that may have roles in chromosome location and anchorage, e.g. emerin and A-type lamins. (portlandpress.com)
  • Methylation of XIST is the switch that starts the process, recruiting DC1, and subsequently the proteins that inactivate the X chromosome. (drugdiscoverynews.com)
  • If we can understand how the normal X chromosome is turned off, we can start to figure out how to turn it back on and get the body to produce those necessary proteins," Jaffrey said. (drugdiscoverynews.com)
  • Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14. (jcvi.org)
  • All isolates were tested by SCC mec element typing and multilocus sequence typing (MLST) ( 9 ) and were analyzed for the Panton-Valentine leukocidin (PVL) gene ( 10 ) and drug susceptibility to erythromycin, clindamycin, gentamicin, amikacin, ciprofloxacin, levofloxacin, tetracycline, trimethoprim-sulfamethoxazole, rifampin, and vancomycin by using the disk diffusion method ( 11 ). (cdc.gov)