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  • genome
  • Using these 3D models, we have begun to unravel the basic principles of chromosome structure and its role in how our genome functions. (redorbit.com)
  • The intricate folds help to unravel how chromosomes interact and how genome functions are controlled. (redorbit.com)
  • Francki MG, Langridge P (1994) The molecular identification of the midget chromosome from the rye genome. (springer.com)
  • Models of evolution of the genome structure and HCEs initially faced considerable algorithmic challenges, which gave rise to (often unnatural) constraints on these models, even for conceptually simple tasks such as the calculation of distance between two structures or the identification of UCEs. (mdpi.com)
  • These approaches have led us to an unexpected result: for some organelles and taxa, the genome structure and HCE set, despite themselves containing relatively little information, still adequately resolve the evolution of species. (mdpi.com)
  • Instead of the term "chromosome structure", the terms "genome" or even "genotype" are used sometimes [ 3 - 5 ].We prefer the term "chromosome structure", [ 6 ], to outline the distinction between the genome as a biological notion and the considered model. (biomedcentral.com)
  • The details of the structure of specific fragments of native chromosomes are not well known in any organism, mainly because of a lack of techniques available to study the structure of specific parts of the genome. (grantome.com)
  • Genomes
  • Gershgorin RA, Gorbunov KY, Zverkov OA, Rubanov LI, Seliverstov AV, Lyubetsky VA. Highly Conserved Elements and Chromosome Structure Evolution in Mitochondrial Genomes in Ciliates. (mdpi.com)
  • double helix
  • From the very early stages of structural studies of DNA by X-ray diffraction and biochemical means, molecular models such as the Watson-Crick nucleic acid double helix model were successfully employed to solve the 'puzzle' of DNA structure, and also find how the latter relates to its key functions in living cells. (wikipedia.org)
  • The first reports of a double helix molecular model of B-DNA structure were made by James Watson and Francis Crick in 1953. (wikipedia.org)
  • In 1953, Watson and Crick discovered the double helix structure of DNA. (wikipedia.org)
  • 1988
  • Nakata N, Asami H, Yasamuro Y, Sasaki M (1988) Role and transmission of midget chromosome found in rye cytoplasmic Chinese Spring line. (springer.com)
  • occur
  • In a post back in September, I quickly summarized the abnormalities that can occur with chromosomes as a whole (such as deletions, insertions, transversions, etc). (labmedicineblog.com)
  • These differences are chromosome anomalies, and they can occur in a variety of ways. (springer.com)
  • organization
  • Chromosome conformation capture techniques (often abbreviated to 3C technologies or 3C-based methods) are a set of molecular biology methods used to analyze the spatial organization of chromatin in a cell. (wikipedia.org)
  • microscopic
  • Dr Peter Fraser of the Babraham Institute explains: "The image of a chromosome, an X-shaped blob of DNA, is familiar to many but this microscopic portrait of a chromosome actually shows a structure that occurs only transiently in cells - at a point when they are just about to divide. (redorbit.com)
  • Bjornsti M-A, Hobot JA, Kelus AS, Villiger W, Kellenberger E (1986) New electron microscopic data on the structure of the nucleoid and their functional consequences. (springer.com)
  • nucleoid
  • One indication of these fluctuations in three-dimensional structure is that the shape of the bacterial nucleoid is irregular and varies in different cells in the same culture. (springer.com)
  • crossover
  • Furthermore, the numbers of crossovers and chiasmata are reduced in the absence of TRIP13, and their distribution along the chromosomes is altered, suggesting a role for TRIP13 in aspects of crossover formation and/or control. (uva.nl)
  • evidence
  • To assist in better understanding population dynamics in this region, evidence is presented herein on local population structure in the Arabian Peninsula, based on Y-STR characterisation in four Arabian samples and its comparison in a broad geographical scale. (blogspot.com)
  • single
  • It involves creating thousands of molecular measurements of chromosomes in single cells, using the latest DNA sequencing technology. (redorbit.com)
  • Scientists have been able to develop the 3D structures of chromosomes in a single cell. (wikipedia.org)
  • Examples include single photon interferometry through two objective lenses to give extremely accurate depth information about a single fluorophore and three-dimensional structured illumination microscopy. (wikipedia.org)
  • genetic
  • Our results demonstrate that geography played an important role in shaping the genetic structure of the region around the Near-East. (blogspot.com)