• BubR1
  • Figure: Localization of BubR1 (red) on chromosomes (blue) during cell division. (ku.dk)
  • This work provides a novel unifying model for the function of BubR1 in chromosome segregation that can explain previous seemingly conflicting results in the field", says Jakob Nilsson. (ku.dk)
  • The researches now aim to use this novel model to better understand other aspects of chromosome segregation and investigate if BubR1 function is affected in human diseases such as cancer. (ku.dk)
  • tumors
  • As most solid tumors are aneuploid it has been hypothesized that chromosome missegregation drives or supports the cancer transformation process. (ieo.it)