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  • rearrangements
  • Inversions are balanced structural chromosome rearrangements, which can influence gene expression and the risk of unbalanced chromosome constitution in offspring. (biomedcentral.com)
  • These DNA rearrangements do not include the putative origin of DNA replication but move within the same replichore, i.e., the same replicating half of the chromosome (delimited by the replication origin and terminus). (jcvi.org)
  • Also, based on PCR amplification and sequence analysis of the DNA joints that are associated with the major rearrangements, the overall chromosome architecture was found to be conserved at most DNA joints for other strains of T. neapolitana. (jcvi.org)
  • Taken together, the results from this analysis suggest that the observed chromosomal rearrangements in the Thermotogales likely occurred by successive inversions after their divergence from a common ancestor and before strain diversification. (jcvi.org)
  • Bafna, V., Pevzner, P.A.: Sorting by reversals: genome rearrangements in plant organelles and evolutionary history of X chromosome. (springer.com)
  • I am using genomic sequence data from a clade of 13 grassfinch species, including subspecies for 8 of which, in order to 1) recover the phylogenetic relationships of this recalcitrant group, 2) examine the frequency of speciation with gene flow, and 3) characterize the history of chromosomal inversion evolution between taxa and the evolutionary context in which these rearrangements have occurred. (danielmarchooper.com)
  • pair
  • Its identification was aided by the repeated observation of the same pair of 150 kb long duplications present in cis on chromosome 21 in three Czech families subjected to microarray analysis. (biomedcentral.com)
  • The presence of the same pair of duplications in additional individuals reported in public databases indicates that the inversion may also be present in other populations. (biomedcentral.com)
  • When the chromosome carries large heterochromatic segments at its base, the distal heterochromatin many tend to pair with its own base in preference to pairing with the Y. Such pairing may occur in either direction, i.e., eucentrically or dyscentrically, as may pairing between the X and Y. Reversal of ordinary pairing relationships may result in the formation of dicentric bridges, and the evidence indicates that such bridges break at anaphase. (openthesis.org)
  • These species have typical avian karyotypes that consist of several pairs of relatively large macrochromosomes (chromosomes 1-10 and a pair of sex chromosomes, ZW in females and ZZ in males) and numerous tiny microchromosomes. (springer.com)
  • Karyotype
  • Using karyotype records for over 400 species from 59 families in the most species-rich group of birds (order Passeriformes ), I examine support for alternative theoretical models of inversion evolution that rest on contradictory predictions regarding the likelihood of inversion fixation and variance in the speciation history, demography, and ecology of species. (danielmarchooper.com)
  • To determine the origin of addition material on chromosome 14 we performed parental karyotype analysis. (biomedcentral.com)
  • segment
  • The finding prompted us to hypothesise that this co-occurrence of two remote duplications could be associated with an inversion of the intervening segment, and this speculation turned out to be right. (biomedcentral.com)
  • characterize
  • We genetically and phenotypically characterize a segregating inversion ( inv6 ) in the Iron Mountain (IM) population of Mimulus guttatus (yellow monkeyflower). (genetics.org)
  • divergence
  • To explore the nature of this divergence, we used high-resolution comparative fluorescent in situ hybridization mapping on giant lampbrush chromosomes (LBCs) from growing oocytes. (springer.com)
  • duplications
  • The inversion was confirmed in a series of FISH experiments which also showed that the second copy of each of the duplications was always located at the opposite end of the inversion. (biomedcentral.com)
  • Three out of the total of about 4000 chromosomes 21 examined in our sample carried the duplications and were inverted, corresponding to carrier frequency of about 1/660. (biomedcentral.com)
  • disorders
  • Our mission is to provide support to parents of children born with rare chromosome disorders, to gather & disseminate information, & to promote research & a positive community understanding of these disorders. (diseaseinfosearch.org)