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Chromatography, High Pressure LiquidChromatography, AffinityChromatography, GelChromatographyChromatography, Ion ExchangeChromatography, GasChromatography, Thin LayerChromatography, LiquidMolecular Sequence DataMolecular WeightAmino Acid SequenceChromatography, DEAE-CelluloseElectrophoresis, Polyacrylamide GelKineticsMass SpectrometryBiological ProductsChromatography, AgaroseGas Chromatography-Mass SpectrometryBase SequenceChromatography, Reverse-PhaseSubstrate SpecificityAmino AcidsEscherichia coliChromatography, PaperHydrogen-Ion ConcentrationCloning, MolecularCattleSpectrophotometry, UltravioletChemistryChemical PhenomenaTandem Mass SpectrometrySpectrometry, Mass, Electrospray IonizationSepharoseRecombinant ProteinsHydrolysisMagnetic Resonance SpectroscopyMolecular StructureBacterial ProteinsDairy ProductsCarbohydratesPeptide FragmentsStereoisomerismTemperatureProtein BindingIsoelectric FocusingRabbitsLiverSequence Homology, Amino AcidCarbohydrate SequenceCell LineDrug StabilityOligosaccharidesMutationOxidation-ReductionChemical FractionationPeptidesMethodsIsoelectric PointConsumer Product SafetyBinding SitesCountercurrent DistributionChromatography, Micellar Electrokinetic CapillaryMacromolecular SubstancesIndicators and ReagentsSolubilityTrypsinGlycosylation End Products, AdvancedDNAGenes, BacterialGlycoproteinsSpecies SpecificityPlasmidsPolymerase Chain ReactionReproducibility of ResultsTime FactorsRNA, MessengerReference StandardsMeat ProductsImmunodiffusionFatty AcidsProteinsCells, CulturedHot TemperatureSwinePolysaccharidesPlant ExtractsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationHydroxyapatitesCarrier ProteinsProduct LabelingIsoenzymesCalibrationGlycoside HydrolasesCatalysisBiological AssayFermentationRadioimmunoassayBiotransformationCarbohydrate ConformationIsomerism
HPLCThin-Layer ChromatoAffinity chromatographyPurificationPopularity of hyphenated chromatography techniquesFlash chromatographyExchange chromatographyResinsTandem mass spectroSupercritical Fluid Chromato2022Column chromatographyCapillary zone electrophoAnionMarket segmentationHydrolysisColumnsResinFiltrationDetectionLiquidConsumablesAgilentIonsReagentsSeparatesLaboratorySpectrometryApplicationsSeparationMassProteinPreparativePhasesCompoundsTechnique2019PurifyAnalysisForecastReproducibilityQuantitatively and qualitativelyRegulatorySizeProcedureExposureStationaryFormulationWidelyScopeParticlesHighTechniquesBiotherapeuticPharmaceutical industryInjectionChemicalsInsights
HPLC9
Thin-Layer Chromato1
Affinity chromatography1
  • Researchers have demonstrated ATR-FTIR as a tool to monitor affinity chromatography purification of monoclonal antibody, but the measurement requires repacking of the resin and so cannot be directly applied to perform continuous monitoring of process scale chromatography 6 . (nature.com)
Purification18
  • Prepacked columns for high-resolution purification of proteins and other biomolecules by ion exchange chromatography. (fishersci.com)
  • Sartorius experts represent extensive experience in chromatography and purification of biomolecules as well as analytical methods development. (sartorius.com)
  • Benefit from all the attributes of monolithic chromatography with a range of strong and weak anion and cation exchangers to meet the needs for purification of large biomolecules. (sartorius.com)
  • The first application demonstrates the monitoring of protein A ligand density and foulant concentration for assessing performance of protein A chromatography resin during purification of monoclonal antibodies. (nature.com)
  • The second application involves monitoring of foulant deposition during multimode cation exchange chromatography based purification of human serum albumin. (nature.com)
  • Chromatographic separation continues to be the mainstay for purification of biotherapeutic products. (nature.com)
  • The versatility of the approach has been demonstrated by successful implementation in three case studies that involve use of three different modes of process chromatography for purification of three different biotherapeutic products. (nature.com)
  • Home 1 / 2 / Chromatography 3 / Laboratory and Process Scale Purification Chromatography: A Driver and. (strategic-directions.com)
  • Purification chromatography is an indispensable tool for a variety of applications in pharma/biotech, petrochemicals and the food/beverage industry. (strategic-directions.com)
  • Purification chromatography is used in almost every biopharmaceutical production process, and is the go-to sample prep technique in the laboratory. (strategic-directions.com)
  • Its connection to the high-flying biopharmaceutical industry has helped to drive very strong growth in the purification chromatography market. (strategic-directions.com)
  • The purpose of this report is to provide a strategic perspective on the current state of the market and the potential demand for purification chromatography techniques. (strategic-directions.com)
  • This report includes a survey of 174 scientists and engineers that provide opinions of their use of process and lab-scale purification chromatography. (strategic-directions.com)
  • Byrne, P. A., Rajendran, K. V., Muldoon, J. and Gilheany, D. G. (2012) 'A convenient and mild chromatography-free method for the purification of the products of Wittig and Appel reactions', Organic & Biomolecular Chemistry, 10(17), pp. 3531-3537. (ucc.ie)
  • Generally, in biochemical protein purification applications, size exclusion chromatography (SEC) is the last step used. (goldbio.com)
  • Plain agarose beads are used in gel filtration chromatography (or molecular exclusion chromatography) as well as for activating beads for biomolecule purification or immobilization. (goldbio.com)
  • Cross-linked agarose beads are used in gel filtration chromatography (or molecular exclusion chromatography) as well as for activating beads for biomolecule purification or immobilization. (goldbio.com)
  • An overview of services and support offered by Bio-Rad Chromatography Scientists, including the development and optimization of purification platforms to meet today's manufacturing demands. (bio-rad.com)
Popularity of hyphenated chromatography techniques1
Flash chromatography2
Exchange chromatography10
  • Ion chromatography (or ion-exchange chromatography) is a form of chromatography that separates ions and ionizable polar molecules based on their affinity to the ion exchanger. (wikipedia.org)
  • Cation-exchange chromatography is used when the molecule of interest is positively charged. (wikipedia.org)
  • Anion-exchange chromatography is when the stationary phase is positively charged and negatively charged molecules (meaning that pH for chromatography is greater than the pI) are loaded to be attracted to it. (wikipedia.org)
  • Cation exchange chromatography is used when the desired molecules to separate are cations and anion exchange chromatography is used to separate anions. (wikipedia.org)
  • For example, when cation exchange chromatography is used, certain cations will elute out first and others later. (wikipedia.org)
  • However, there are also disadvantages involved when performing ion-exchange chromatography, such as constant evolution with the technique which leads to the inconsistency from column to column. (wikipedia.org)
  • Starting from 1947, Spedding and Powell used displacement ion-exchange chromatography for the separation of the rare earths. (wikipedia.org)
  • The boom of Ion exchange chromatography primarily began between 1935-1950 during World War II and it was through the "Manhattan project" that applications and IC were significantly extended. (wikipedia.org)
  • The monitoring system used, both in the on- and off-line mode, was based on continuous flow microdialysis sampling (CFMS) coupled to anion exchange chromatography and integrated pulsed electrochemical detection (IPED). (lu.se)
  • A microdialysis probe equipped with a 5-mm polysulfone (SPS 4005) membrane, with a molecular-weight cut-off of 5 kDa, was used to sample the hydrolysis products of native wheat starch at 90 degrees C. Characteristic fingerprint separations were achieved by anion exchange chromatography after enzymatic hydrolysis. (lu.se)
Resins3
  • We can develop customized products to suit your specific needs, including custom bonding of Grace's or your chromatography resins. (grace.com)
  • In order to improve process economics, it is common practice to reuse chromatography resins. (nature.com)
  • Bio-Rad manufactures a wide range of chromatography resins for process separations, providing process developers with great flexibility and high productivity. (bio-rad.com)
Tandem mass spectro2
Supercritical Fluid Chromato1
20223
  • Dublin, Oct. 06, 2022 (GLOBE NEWSWIRE) -- The "Gas Chromatography Market By Product, By End User: Global Opportunity Analysis and Industry Forecast, 2021-2031" report has been added to ResearchAndMarkets.com's offering. (globenewswire.com)
  • According to this report the gas chromatography market was valued at $1.7 billion in 2021, and is estimated to reach $3.2 billion by 2031, growing at a CAGR of 6.1% from 2022 to 2031. (globenewswire.com)
  • Data Bridge Market Research analyses that the chromatography equipment market which was USD 10839.10 million in 2021, would rocket up to USD 16888.58 million by 2029, and is expected to undergo a CAGR of 5.70% during the forecast period 2022 to 2029. (databridgemarketresearch.com)
Column chromatography1
  • Irrespective of the interactions that are being brought, liquid column chromatography is taken up in six steps: Column equilibration, Sample loading, Washing, Elution, Final column washing and Column regeneration. (futuremarketinsights.com)
Capillary zone electropho2
  • Two original products, Eprex (epoetin alfa) and Dynepo (epoetin delta), and two biosimilar products, Binocrit (epoetin alfa) and Retacrit (epoetin zeta), were compared using (1) high performance size exclusion chromatography, (2) ELISA, (3) SDS-PAGE, (4) capillary zone electrophoresis and (5) in-vivo potency. (springer.com)
  • Because a limited amount of EPO products was available, we were restricted to the common assays used for quality control: high performance size exclusion chromatography (HP-SEC) to assess monomer and aggregate content, ELISA to determine EPO protein content, SDS-PAGE under non-reducing conditions to detect possible fragmentation and covalent protein aggregates, capillary zone electrophoresis (CZE) for isoform profiling and a normocythemic mouse assay to test for potency. (springer.com)
Anion3
  • The two types of ion chromatography are anion-exchange and cation-exchange. (wikipedia.org)
  • At the start of the 1950s, Kraus and Nelson demonstrated the use of many analytical methods for metal ions dependent on their separation of their chloride, fluoride, nitrate or sulfate complexes by anion chromatography. (wikipedia.org)
  • In 1979, a method for anion chromatography with non-suppressed conductivity detection was introduced by Gjerde et al. (wikipedia.org)
Market segmentation1
Hydrolysis1
  • Data from the monitoring of the hydrolysis of wheat starch indicated that, after 1 h, glucose and maltooligosaccharides up to DP 7 were the main hydrolysis products and thus enabled optimization of a liquefication step during the production of L-lactic acid. (lu.se)
Columns3
  • Pre-configured product packs are also available, a combination of columns and a protocol to suit specific needs. (sartorius.com)
  • In contrast, advancement in gas chromatography columns for petrochemical applications, adoption of gas chromatography in R&D for cancer detection are some of the factors expected to offer lucrative growth opportunities for players in the chromatography market. (globenewswire.com)
  • As chromatography columns are used to purify the product in downstream processing for drug development, the rise in various illnesses and chronic diseases is expected to increase demand for chromatography equipment. (databridgemarketresearch.com)
Resin4
  • Resin reuse, however, is known to impact product yield and in some cases even product quality. (nature.com)
  • Resin fouling is a complex problem that can be influenced by several factors such as impurities or residual product deposition on pores which may either block pores and/or block binding sites on the surface of resin. (nature.com)
  • In contrast, fluorescence spectroscopy is particularly well suited to monitor fouling of chromatography resin. (nature.com)
  • In this communication, we propose a robust fluorescence based approach to monitor fouling in process chromatography resin by presenting its use in three independent studies 7 . (nature.com)
Filtration1
  • VYKING™ superparamagnetic silica features a novel particle design that clads a superparamagnetic core with silica to eliminate the need for chromatography, centrifugation, or vacuum filtration steps required in typical biomolecule purifications. (grace.com)
Detection2
  • However, some components may have weak UV chromophores if UV detection is being used or be completely retained on the liquid chromatography column. (europeanpharmaceuticalreview.com)
  • Mixtures of neutralizing anti- detection of the unique peptide products by mass spec- bodies are given to mice in conjunction with the sample. (cdc.gov)
Liquid21
Consumables1
  • By product, the market is segmented into instruments and consumables & accessories. (globenewswire.com)
Agilent1
  • The Agilent Essential Chromatography and Spectroscopy Catalog Series is a set of quick-reference catalogs and mini-catalogs, conveniently arranged by subject-such as GC, LC, spectroscopy, and sample preparation. (agilent.com)
Ions5
  • A handful measures and protocols for 1960s and 1970s (Parascandola, of countries and jurisdictions have evaluation, so that the impact of 20 5), and it to k decades before already adopted legislation requirng future regulations can be as es ed. epidemiologic studies provided reporting and testing of tobac o In 19 9, a WHO Conference on the definitve evidence that changes in product contents and emis ions. (who.int)
  • We now know that much of product contents and emis ions, as benefits, minimize unintended con- the ap arent decline was due to the wel as manufacturers' disclosures sequences, and thereby foster use of filter ventilation, which about he product (Figure 5.6). (who.int)
  • The Conference of the Parties, in consultation with competent international bodies, shal propose guidelines for testing and measuring the contents and emis ions of tobac o products, and for the regulation of these contents and emis ions. (who.int)
  • Each Party shal, in ac ordance with its national aw, adopt and implement efective legislative, executive, administrative or other measures requirng manufacturers and importers of tobac o products to disclose to governmental authorites information about he contents and emis ions of tobac o products. (who.int)
  • Each Party shal further adopt and implement efective measures for public disclosure of information about he toxic constiuents of the tobac o products and the emis ions that hey may produce. (who.int)
Reagents6
  • The global market for chromatography reagents will grow from $8.3 billion in 2014 to nearly $11 billion by 2019 at a compound annual growth rate (CAGR) of 5.2% between 2014 and 2019. (bccresearch.com)
  • An overview of the global market for reagents for chromatography. (bccresearch.com)
  • Analysis on the market size, market leaders, and factors affecting the market of chromatography reagents from the perspective of its end users, which includes the pharma and biotech, food and beverages, environmental agencies and other sectors. (bccresearch.com)
  • Comparisons, usage statistics, and the advantages and disadvantages of different types of chromatography products and reagents. (bccresearch.com)
  • The scope of this study encompasses multiple technologies and procedures related to chromatography reagents. (bccresearch.com)
  • The report examines the overall chromatography reagents industry and the types of technologies currently in use as well as future technological developments, end-user markets and regional distribution, in addition to regulatory influences, patents filed and pipeline products that affect product distribution. (bccresearch.com)
Separates1
Laboratory2
  • Those who have purchased the products described are entitled to print a copy for their use, or use by their research laboratory. (basinc.com)
  • Laboratory-based product esting on the population, in order to However, it can take decades for remains vitaly important, despite its determine whether regulations are some ef ects, such as changes in limitations for predicting human risk. (who.int)
Spectrometry6
  • Gaseous products from the discharge exhaust were analysed by Gas Chromatography with Mass Spectrometry (GC-MS). The experimental results revealed C 2 H 2 , HCN, and CH 3 CN as the major products. (open.ac.uk)
  • The Department also has an associated flavour analytical suite, including proton transfer reaction mass spectrometry ( PTR-MS ) and gas chromatography ( GC ) suite. (otago.ac.nz)
  • The product peptides derived from the endopeptidase injection containing a sample with more than a minimum activities of BoNTs are detected by matrix-assisted laser- lethal dose show symptoms of botulinum intoxication and desorption ionization time-of-flight mass spectrometry. (cdc.gov)
  • Mice receiving the appropriate anti-BoNT serotype anti- a unique cleavage site on a unique peptide, the mass-spe- body are asymptomatic and survive, while mice treated cific product peptides detected by mass spectrometry dif- with the other serotype antibodies show symptoms of botu- ferentiate active BoNT serotypes. (cdc.gov)
  • Characterization of volatile organic compounds of different pigmented rice after puffing based on gas chromatography-ion migration spectrometry and chemometrics. (bvsalud.org)
  • The distinctness in volatile profiles of pigmented rice with various colors (black, green, purple , red, and yellow) after puffing were assayed through gas chromatography -ion migration spectrometry (GC-IMS) to explore their odor characteristics. (bvsalud.org)
Applications5
  • The TempLog Plus Series Glass Door Chromatography Refrigerators are purpose built for scientific and medical applications requiring superior temperature management and state of the art product security and data logging. (labresprod.com)
  • The Plus Series Chromatography Refrigerators are purpose built for critical cold storage applications, but where built-in data logging functionality may not be a necessity. (labresprod.com)
  • The Basic Series Chromatography Refrigerators can help meet the demand of scientific and medical applications at budget-easing price points or satisfy any general purpose cold storage needs. (labresprod.com)
  • The main driving factors that foster growth of the gas chromatography market are rise in applications of gas chromatography in various fields such as pharmaceutical industries, chemical industry, food industry, environmental testing laboratories, and forensic science. (globenewswire.com)
  • The expansion of chromatography applications across numerous sectors of the food and beverage and pharmaceutical industries is the main factor fuelling the market for chromatograpy equipment. (databridgemarketresearch.com)
Separation1
  • Join us on a journey through the monolith matrix to discover how convective chromatography supports the robust separation of large biomolecules. (sartorius.com)
Mass4
  • The combination of chromatography with mass spectroscopy is a very useful technique which is being increasingly used by polymer chemists to improve existing polymers and to discover new ones with specific physical properties such as thermal stability and retention of properties over a long service life. (chemtec.org)
  • This technique is extremely powerful for the analysis and characterisation of polymers and is often based on the use of controlled chromatography - mass spectroscopy to measure a polymer's decomposition with techniques such as pyrolysis, followed by chromatography to separate any breakdown product, and, finally, mass spectroscopy, to achieve an unequivocal identification of the pyrolysis products obtained. (chemtec.org)
  • Pyrolysis chromatography-mass spectroscopy is a method of studying the structure of polymers which involves subjecting the polymer pyrolysis products to a chromatographic technique to simplify subsequent analysis and, finally mass spectroscopy to identify the pyrolysis products with the possibility of deducing finer details of polymer structure than were previously attainable by classical methods (Chapters 9-11). (chemtec.org)
  • Urinary VOC concentrations were measured using gas chromatography-mass spectroscopy. (cdc.gov)
Protein2
  • However, ion chromatography must be done in conditions that are one unit away from the isoelectric point of a protein. (wikipedia.org)
  • Biosimilars are attempted copies of the original product, but due to the complex structure and intricate manufacturing processes of protein drugs, they are only similar to the original product ( 1 , 2 ). (springer.com)
Preparative1
  • This opportunity is perfectly aligned with our strategy to invest in preparative chromatography and complete our portfolio of solutions for drug discovery and development. (foodnavigator.com)
Phases1
  • DAVISIL ® silica products come in a granular form and are offered in a wide range of particle and pore sizes and in many phases from small to multi-ton quantities. (grace.com)
Compounds5
  • Gas chromatography is a chromatography technique that can separate and analyze volatile compounds in gas phase. (globenewswire.com)
  • Chromatography methods are used to organic and inorganic compounds such as separate proteins, nucleic acids, or small molecules in complex mixtures and others. (futuremarketinsights.com)
  • Feminine hygiene products and volatile organic compounds in reproductive-aged women across the menstrual cycle: a longitudinal pilot study. (cdc.gov)
  • Background: Volatile organic compounds (VOCs) have been detected in feminine hygiene products (FHPs), especially in tampons and sanitary pads. (cdc.gov)
  • The routes of human exposure to these compounds include industrial pollution, pesticide use, food consumption, and use of personal care products. (cdc.gov)
Technique1
20191
  • It provides a breakdown of demand by product, region and industry segments, all of which are forecast through 2019. (strategic-directions.com)
Purify1
Analysis3
  • Which type of chromatography is best for cannabis analysis? (news-medical.net)
  • This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the gas chromatography market analysis from 2021 to 2031 to identify the prevailing gas chromatography market opportunities. (globenewswire.com)
  • The report includes the analysis of the regional as well as global gas chromatography market trends, key players, market segments, application areas, and market growth strategies. (globenewswire.com)
Forecast1
  • Moreover, technologically advanced products such as temperature-programmed chip-based GC, GCxGC, and new GC phase including nanoparticles, ionic liquids, and co-polymers are expected to propel the demand for gas chromatography procedures during the forecast period. (globenewswire.com)
Reproducibility1
Quantitatively and qualitatively1
  • The results can be used to analyse finished drug products and their ingredients quantitatively and qualitatively during the manufacturing process. (europeanpharmaceuticalreview.com)
Regulatory4
  • The FDA writes in its FAERS information that after evaluation, "the FDA may take regulatory action(s) to improve product safety and protect the public health, such as updating a product's labeling information, restricting the use of the drug, communicating new safety information to the public, or, in rare cases, removing a product from the market. (medscape.com)
  • WHO establishes and publishes specifications2 for technical material and related formulations of public health pesticides with the objective that these specifications may be used to provide an international point of reference against which products can be judged either for regulatory purposes or in commercial dealings. (who.int)
  • The Expert Committee on Specifications for Pharmaceutical Preparations advises the Director-General in the area of medicines' quality assurance and provides regulatory tools for medical products. (who.int)
  • A European Union gens becomes a greater regulatory issue within ban on in vivo testing of cosmetic and toiletry industry when they could be present in consumer ingredients will come into force in 2013 for the products, for example, personal care products that end-point of skin sensitization (9). (cdc.gov)
Size2
  • Our actionable insights support assessing the size and attractiveness of markets, optimizing product configurations and pricing, validating corporate acquisitions, measuring of customers' brand loyalty, and evaluating of your brand strength and positioning. (strategic-directions.com)
  • GoldBio offers a large selection of agarose beads for size exclusion chromatography, which are excellent for your unique research needs. (goldbio.com)
Procedure1
  • WHO specifications under the New Procedure do not necessarily apply to nominally similar products of other manufacturer(s), nor to those where the active ingredient is produced by other routes of manufacture. (who.int)
Exposure2
  • However, little is known about whether menstrual products can contribute to VOC exposure in women. (cdc.gov)
  • The introduction of Clopidogrel/Acetylsalicylic acid Mylan manufactured by Mylan S.A.S is considered unlikely to result in any significant increase in the combined sales volumes for all clopidogrel/acetylsalicylic acid containing products and the exposure of the environment to the active substance. (janusinfo.se)
Stationary1
  • The molecule is positively charged because the pH for chromatography is less than the pI (a/k/a pH(I)). In this type of chromatography, the stationary phase is negatively charged and positively charged molecules are loaded to be attracted to it. (wikipedia.org)
Formulation1
  • In 1998, the formulation of the first EPO product Eprex was changed. (springer.com)
Widely2
  • Chiral chromatography is widely used to make the first few grams of enantiomers, when the compound is needed pure and quickly, without considering future manufacturing. (outsourcing-pharma.com)
  • Parabens, a group of alkyl (e.g., methyl, ethyl, propyl, butyl) esters of p-hydroxybenzoic acid, are widely used as antimicrobial preservatives in personal care products, and can also be used in pharmaceuticals, as well as in food and beverage processing. (cdc.gov)
Scope1
  • WHO has the possibility to extend the scope of the specifications to similar products but only when the JMPS has been satisfied that the additional products are equivalent to that which formed the basis of the reference specification. (who.int)
Particles1
  • Large molecules are used commonly in modern gene therapy and vaccines products, and include virus particles, vesicles, RNA, plasmids, and other forms of DNA. (sartorius.com)
High2
  • However, high cost of gas chromatography equipment and lack of adequate skilled professionals to operate gas chromatography instruments and perform the techniques in the pharmaceutical industry may hamper the growth of the market. (globenewswire.com)
  • and their products play an important role in A total of 257 samples of ultra-high the food supply, job generation and income for temperature (UHT) treated milk (n=125), society. (bvsalud.org)
Techniques2
  • Values of average conversion rates and chemical content of the obtained products (GC, TG and GPC techniques) were compared. (springer.com)
  • Careful donor selection, vigilant screening, lookback programs, inactivation of pathogens, and continuous efforts to develop new techniques for screening and inactivation will be required to make blood products, and thus blood transfusions, continually safe. (medscape.com)
Biotherapeutic1
  • Although ubiquitous in biopharmaceutical processes, chromatographic steps are major contributors to the overall cost of raw material in the manufacture of biotherapeutic products. (nature.com)
Pharmaceutical industry1
  • In the pharmaceutical industry, all manufactured products need to be of the highest quality to ensure the least risk to patients. (europeanpharmaceuticalreview.com)
Injection1
Chemicals1
  • Beginning in NHANES 2013-2014, the Environmental Phenols and Parabens dataset (formerly EPH) was combined with the Pesticides - Environmental - Urine dataset (formerly PP) and renamed Personal Care and Consumer Product Chemicals and Metabolites (EPHPP_H). (cdc.gov)
Insights1
  • The survey also provides valuable insights into the way they perceive vendors, offering areas for improvement and ideas for further product development. (strategic-directions.com)