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  • Biological
  • Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage. (springer.com)
  • Unlike any other title on the topic, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction is an invaluable addition to the literature and will serve as an indispensable resource for basic scientists with an interest in sperm biology and for urologists, gynecologists, reproductive endocrinologists, and embryologists working in the field of infertility. (springer.com)
  • cellular
  • This volume brings together a wide range of methods to explore the structure and function of bacterial chromatin from molecular to the cellular scale. (springer.com)
  • Likewise, chromatin structure is responsive to complicated manipulations by the cellular machinery that make the DNA more or less accessible for the transcriptional apparatus. (asbmb.org)
  • Structure
  • In pluripotent stem cells or multipotent stem/progenitor cells, lineage/cell-specific enhancers are silent by repressive chromatin structure. (nih.gov)
  • forms
  • While these changes are going on in the chromatin the Amphiaster forms. (dictionary.com)
  • A chromatin loop forms when an enhancer and a promoter, two widely separated elements in a DNA sequence, come into contact as they carry out gene activity. (eurekalert.org)
  • function
  • The work covers the fundamental principles of sperm chromatin architecture and function, the proposed modes of DNA damage and repair, the tests of sperm DNA damage, the clinical aspects of DNA damage and the impact of DNA damage on reproductive outcome. (springer.com)
  • IMAGE
  • Because they require toxic fluorescent dyes to enhance contrast, previous techniques could not image chromatin in living cells without killing or perturbing the cells. (eurekalert.org)
  • form
  • PHO5 chromatin in the transcriptionally repressed state was excised from yeast chromosomes in circular form by recombination and purified by affinity chromatography as described ( Fig. S1 A and B ) ( 10 , 11 ). (pnas.org)
  • study
  • Not only is the technique label-free, allowing researchers to study chromatin within unharmed, living cells, but it does so with high-throughput and at very low cost. (eurekalert.org)
  • light
  • Called live cell Partial Wave Spectroscopic (PWS) microscopy, the technique detects chromatin by using scattered light. (eurekalert.org)