• Chondrogenesis at the US National Library of Medicine Medical Subject Headings (MeSH) http://encyclopedia.farlex.com/chondrogenesis https://www.newscientist.com/article/dn16849-artificial-cartilage-performs-better-than-the-real-thing.html http://www.medicalnewstoday.com/articles/100359.php "BMPs Are Required at Two Steps of Limb Chondrogenesis: Formation of Prechondrogenic Condensations and Their Differentiation into Chondrocytes - ScienceDirect" (PDF). (wikipedia.org)
  • Trattnig, "Magnetic resonance observation of cartilage repair tissue (MOCART) forthe evaluation of autologous chondrocyte transplantation: determination of interobserver variability and correlation to clinical outcome after 2 years, " European Journal of Radiology, vol. (thefreedictionary.com)
  • The low level of superoxide anions O 2- produced by chondrocytes in comparison with neutrophils may be involved in signal transduction and may be implicated in the structural and functional alterations of cartilage matrix observed in arthritis and osteoarthritis. (springer.com)
  • Chondrification (also known as chondrogenesis) is the process by which cartilage is formed from condensed mesenchyme tissue, which differentiates into chondrocytes and begins secreting the molecules that form the extracellular matrix. (wikipedia.org)
  • We demonstrate that increasing ROS levels induce chondrocyte hypertrophy. (rupress.org)
  • L-Sox5 and Sox6 are thought to induce the activation of the Col2a1 and the Col11a2 genes, and to repress the expression of Cbfa1, a marker for late stage Chondrocytes. (wikipedia.org)
  • Light micrograph of hyaline cartilage showing its chondrocytes and organelles , lacunae and matrix . (wikipedia.org)
  • The chondroblast is now a mature chondrocyte that is usually inactive but can still secrete and degrade the matrix, depending on conditions. (wikipedia.org)
  • The matrix is removed enzymatically and the chondrocytes isolated. (wikipedia.org)
  • Fresh chondrocytes showed a high mitotic rate and abundant matrix was present up to 60 days of culture. (scielo.br)
  • Pluripotent hESc, are established as feeder-free cultures4 prior to DDP being carried out in monolayer culture on a sequence of matrix protein-coated surfaces with a chemicallydefined medium sequentially supplemented with growth factors to directdifferentiation through developmental intermediate cell populations of primitive streak/mesendoderm (Stage 1), mesoderm (Stage 2) and then chondrocytes (Stage 3) (Figure 1). (stembook.org)
  • Probable reason could be the deposition of iron in chondrocytes and matrix. (thefreedictionary.com)
  • We evidenced reduced chondrocyte nuclei, with hardly any lacunae present, surrounded by generous cartilaginous matrix with fibers (Figure 7). (thefreedictionary.com)
  • Several cell surface receptors that mediate cell/matrix interactions have been identified in growth plate chondrocytes. (pubmedcentralcanada.ca)
  • Chondrocalcin is internalized by chondrocytes and triggers cartilage destruction via an interleukin-1β-dependent pathway, Matrix Biology, November 2013. (wikipedia.org)
  • Chondrocytes sense and convert the mechanical signals they receive into biochemical signals, which subsequently direct and mediate both anabolic (matrix building) and catabolic (matrix degrading) processes. (wikipedia.org)
  • This study evaluated chondrogenesis within a nanofiber polymeric scaffold seeded with isolated untreated chondrocytes, isolated chondrocytes genetically engineered with adenoviral (Ad) bone morphogenetic protein (BMP)-2, or isolated chondrocytes genetically engineered with green fluorescent protein (Ad-GFP). (scirp.org)
  • This study demons- trated that chondrocytes can be driven to seed a polycaprolactone nanofiber scaffold by serum gradient and a polycaprolactone nanofiber scaffold containing Ad-BMP2 transduced chondrocytes resulted in grea- ter and accelerated chondrogenesis than controls. (scirp.org)
  • This work shows that three different human immortalized chondrocyte (HIC) cell lines (a gift from M Goldring) and native chondrocytes can generate superoxide anions (O 2- ) constitutively and after activation with PMA or ionomycin. (springer.com)
  • The present study showed important loss of chondrocyte viability under the freezing conditions. (scielo.br)
  • The three HIC cell lines and native chondrocytes contain phagocyte NADPH oxidase components, and Nox2 (gp91phox) analogs as Nox4 and Nox5. (springer.com)
  • This work evaluated the effect of freezing on chondrocytes maintained in culture, aiming the establishment of a cell bank for future application as heterologous implant. (scielo.br)
  • However, chondrocytes from one donor cell isolation out of five remained non-responsive. (diva-portal.org)
  • 17 β -estradiol reduces expression of MMP-1, -3, and -13 in human primary articular chondrocytes from female patients cultured in a three dimensional alginate system," Cell and Tissue Research , vol. 342, no. 2, pp. 283-293, 2010. (hindawi.com)
  • We offer everything you need for your chondrocyte cell culture application. (promocell.com)
  • as well as to mesodermal cell fates: cardiomyocytes, chondrocytes, T lymphocytes and myeloid precursors. (wikipedia.org)
  • T. Irie, T. Aizawa, and S. Kokubun, "The role of sex hormones in the kinetics of chondrocytes in the growth plate. (hindawi.com)
  • Transmission electron micrograph of a chondrocyte, stained for calcium, showing its nucleus (N) and mitochondria (M). (wikipedia.org)
  • Because inappropriate chondrocyte hypertrophy causes skeletal growth abnormalities such as dwarfism, control of hypertrophy is critical for normal longitudinal bone growth ( 4 - 6 ). (rupress.org)
  • Though some chondrocytes do manage to survive, growth is significantly reduced, resulting in the characteristically short limbs and seemingly unaffected face and torso of those inflicted with the disorder (OMIM 2008). (wikipedia.org)