• When expressed in COS- 1 cells, hVLCS-H2 exhibited cholate:CoA ligase (choloyl-CoA synthetase) activity with both nonisotopic and radioactive assays. (missouristate.edu)
  • 19. Polyethylenimine and sodium cholate-modified ethosomes complex as multidrug carriers for the treatment of melanoma through transdermal delivery. (nih.gov)
  • The double emulsion was then poured drip into a 0.3% (w/v) sodium cholate aqueous solution, and stirred at 37°C for 1 h. (medscape.com)
  • Cholic acid and its derivatives exist in bile as the major component as conjugates of glycine and taurine. (hihnf-stl.com)
  • The typical histopathologic features of hepatocellular cholestasis include the presence of bile within hepatocytes and canalicular spaces, in association with generalized cholate injury. (medscape.com)
  • Typical of obstructive cholestasis is bile plugging of the interlobular bile ducts, portal expansion, and bile duct proliferation in association with centrilobular cholate injury. (medscape.com)
  • [ 13 , 14 ] Fluorescein derivative- (F-PLGA) and rhodamine 6G derivative-grafted poly( D , L -lactic- co -glycolide) (R-PLGA) polymers were synthesized as described by Freichels et al . (medscape.com)
  • Currently, degradation of sterols (such as cholesterol, or phytosterols) by actinobacteria is in the focus of intensive researches due to its exclusive role in pathogenicity of Mycobacterium tuberculosis , and established applications of the non-pathogenic species and their engineered derivatives in biotechnology for production of high-value steroids for the pharmaceutical industry. (biomedcentral.com)