• The catalytic acid base, required to cleave the peroxide O-O bond, is glutamic acid rather than histidine as in horseradish peroxidase. (wikipedia.org)
  • A tight barrier against permeation of horseradish peroxidase into the corneal epithelium exists at the corneal surface adjacent to the tear film. (scite.ai)
  • Horseradish peroxidase is also capable of oxidizing these substrates, but its heme is not covalently bound and becomes damaged during turnover. (wikipedia.org)
  • Immobilization of horseradish peroxidase on PMMA nanofibers incorporated with nanodiamond. (sparrho.com)
  • In the present study, nanodiamond (ND) was blended with polymethyl methacrylate (PMMA) and then electrospun into nanofibers (nfPMMA-ND) for the immobilization of horseradish peroxidase (HRP). (sparrho.com)
  • Horseradish peroxidase and chitosan: activation, immobilization and comparative results. (sparrho.com)
  • The distribution of sodium, choline, sulfate, and chloride ions around two proteins, horseradish peroxidase (HRP) and bovine pancreatic trypsin inhibitor (BPTI), is investigated by means of molecular dynamics simulations with the aim to elucidate ion adsorption at the protein surface. (uni-regensburg.de)
  • Peroxidase-conjugated goat igg fraction to rabbit IgG (whole molecule) is the lyophilized powder of horseradish peroxidase (HRP)-conjugated goat IgG fraction to rabbit IgG (whole molecule) and buffer salts. (mpbio.com)
  • The heme-containing chloroperoxidase (CPO) exhibits peroxidase, catalase and cytochrome P450-like activities in addition to catalyzing halogenation reactions. (wikipedia.org)
  • The unusual Met-Tyr-Trp adduct composed of cross-linked side chains along with an associated mobile Arg is essential for catalase activity in catalase-peroxidases. (rcsb.org)
  • Muscle viability (evaluated by triphenyltetrazolium chloride dye method), malondialdehyde, superoxide dismutase, catalase, and glutathione peroxidase were assessed in muscle samples using a spectrophotometer. (readbyqxmd.com)
  • Glutathione peroxidase and catalase activities were enhanced, while superoxide dismutase activity was depressed in HgCl(2)-treated rats when compared to control and these effects were prevented by ASX. (unboundmedicine.com)
  • We measured the levels of Cd, lipid peroxidation (LPO), nitric oxide, glutathione (GSH), and oxidative enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase, and glutathione reductase (GR) in the whole brain homogenate. (bioscirep.org)
  • 12. The collagen composition of claim 1 wherein the composition is polymerizable by exposing to UV and an initiator selected from the group comprising sodium persulfate, sodium thiosulfate, ferrous chloride tetrahydrate, sodium bisulfite or a combination of the foregoing. (google.com.au)
  • Cystic fibrosis (CF) is caused by alterations in the CF transmembrane conductance regulator (CFTCR) gene that result in deranged sodium and chloride ion transport channels. (hmdb.ca)
  • Sulfate is always strongly attached to the proteins, choline shows a significant, but unspecific, propensity for the protein surfaces, and sodium ions have a weak surface affinity, while chloride has virtually no preference for the protein surface. (uni-regensburg.de)
  • In mixtures of all four ion species in protein solutions, the resulting distributions are almost a superposition of the distributions of sodium sulfate and choline chloride, except that sodium partially replaces choline close to the proteins. (uni-regensburg.de)
  • The product is dialyzed into 0.02M sodium phosphate, 0.14M sodium chloride, pH 7.3, adjusted to standard titer, filtered through a 0.22 µm filter, vialed and lyophilized. (mpbio.com)
  • sodium chloride salt concentration, the amount of green weight, dry weight increase ALW specific leaf weight and leaf area was increased as well. (gasemie-ilkhichi.ir)
  • Chloride peroxidase (EC 1.11.1.10) is a family of enzymes that catalyzes the chlorination of organic compounds. (wikipedia.org)
  • It differs from EC 1.11.1.10 chloride peroxidase in its preference for formation of hypochlorite over the chlorination of organic substrates under physiological conditions (pH 5-8). (qmul.ac.uk)
  • In recent years, the synergistic relationship between NADPH oxidase (NOX)/dual oxidase (DUOX) enzymes and peroxidases has received increased attention. (genetics.org)
  • These enzymes generate the H 2 O 2 required as substrate for the peroxidases. (genetics.org)
  • Thus, glutathione peroxidase (GPx) is one of the enzymes, selenium-dependent type, which is involved on the transformation of reactive oxygen species, catalyzing the reduction of hydrogen peroxide (H 2 O 2 ) or lipoperoxide (L-OOH), using GSH as a reducing agent 5, 6 . (scielo.cl)
  • While the expression of brain SOD2 , CAT, glutathione peroxidase 1, and GR was down-regulated in the Cd-treated group, the expression of these enzymes was up-regulated in rats pretreated with SME. (bioscirep.org)
  • This enzyme combines the inorganic substrates chloride and hydrogen peroxide to produce the equivalent of Cl+, which replaces a proton in hydrocarbon substrate: R-H + Cl− + H2O2 + H+ → R-Cl + 2 H2O In fact the source of "Cl+" is hypochlorous acid (HOCl). (wikipedia.org)
  • This enzyme belongs to the family of oxidoreductases, specifically those acting on a peroxide as acceptors (peroxidases). (wikipedia.org)
  • The systematic name of this enzyme class is chloride:hydrogen-peroxide oxidoreductase. (wikipedia.org)
  • A process for the preparation of a phenolic resin which comprises reacting a phenol with a peroxidase or an oxidase enzyme and a peroxide in an organic solvent containing medium to generate phenolic radicals which react to form a phenolic resin. (freepatentsonline.com)
  • 3. The process of claim 2 wherein said enzyme is a peroxidase enzyme. (freepatentsonline.com)
  • Glucose electrodes were coated with an oxidizing enzyme (peroxidase) which allows hydrogen peroxide to selectively oxidize ascorbate, urate, bilirubin, and acetaminophenol in the presence of glucose. (google.com.au)
  • 3. The biosensor of claim 2, wherein the enzyme is peroxidase. (google.com.au)
  • An enzyme that catalyzes the chlorination of a range of organic molecules, forming stable carbon-chloride bonds. (bvsalud.org)
  • Peroxidase-conjugated goat IgG fraction to rabbit IgG (whole molecule) product is suitable for use as a reagent in enzyme immunoassays (EIA), cell and tissue staining (for light microscopy), cell and tissue labeling (for electron microscopy), and blot immunostaining. (mpbio.com)
  • We postulated that one or more peroxidases produced by Caenorhabditis elegans would act in host defense, possibly in conjunction with BLI-3 , the only NOX/DUOX enzyme encoded by the genome that is expressed. (genetics.org)
  • This study investigated the effect of curcumin on aluminium-induced alterations in ageing-related parameters: lipid peroxidation, superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione-s-transferase (GST), protein kinase C (PKC), Na(+), K(+)-adenosine triphosphatase (Na(+), K(+)-ATPase) and acetylcholinesterase (AChE) in the cerebral cortex and hippocampus of the brain of 10- and 24-month-old rats. (nih.gov)
  • The aim of the present study is to evaluate the effect of Zn excess on the non-enzymatic (anthocyanin and ß-ecdysone) and enzymatic (superoxide dismutase-SOD and guaiacol peroxidase-GPX) antioxidant system of two P. glomerata accessions (JB and GD) grown in hydroponic system and soil, under short- and long-term exposure times. (bvsalud.org)
  • The present light and transmission electron microscopic study reveals that the cationic surfactant, benzalkonium chloride, which is commonly added to eye drops as a preservative, breaks down this barrier. (scite.ai)
  • Symptoms are exacerbated by the preservative benzalkonium chloride (BKC) in the nasal preparations. (springer.com)
  • Another commonly used FQ, levofloxacin (LEV), and the most commonly used preservatives, benzalkonium chloride (BAC), were also used for comparison with MOX. (arvojournals.org)
  • We investigated the therapeutic effects and underlying mechanisms of topical doxycycline in a benzalkonium chloride (BAC)-induced mouse dry eye model. (arvojournals.org)
  • For example, although eosinophil peroxidase is able to oxidize chloride, it preferentially oxidizes bromide. (wikipedia.org)
  • The eosinophil number in blood and eosinophil protein levels in serum (serum eosinophil cationic protein [ECP] and serum eosinophil peroxidase [EPO]) increased significantly in the withdrawal group, and the difference between the groups was significant (P =.02 for all). (nih.gov)
  • Chloride-transporting proteins (CLC) play fundamental roles in many tissues in the plasma membrane as well as in intracellular membranes. (hmdb.ca)
  • In other words, the proteins are trapped between glycine and chloride ion. (ipl.org)
  • Peroxidases form a complex family of proteins that catalyze the oxidoreduction of various substrates using H 2 O 2 . (plantphysiol.org)
  • Many of these peroxidases are functionally associated with members of the NADPH oxidase (NOX)/dual oxidase (DUOX) family of proteins. (genetics.org)
  • therefore, the present study aimed to examine the ameliorative effects of grape seed extract (GSE) on cadmium chloride (CdCl2)‑induced testicular dysfunction of Wistar rats. (spandidos-publications.com)
  • Within 24 h of intramuscular administration of cadmium chloride 15 mg.kg-1 body weight (bw) and mercury chloride 20 mg.kg-1 bw, thyroid peroxidase activity increased significantly over the control with a concomitant rise in the triiodothyronine (T3) titre. (ithyroid.com)
  • The present study evaluated the protective effects of Fragaria ananassa methanolic extract (SME) on cadmium chloride (CdCl 2 )-induced neuronal toxicity in rats. (bioscirep.org)
  • Haloperoxidases are peroxidases that are able to mediate the oxidation of halides by hydrogen peroxide. (wikipedia.org)
  • The Nernst equation shows that hydrogen peroxide can oxidize chloride (E°= 1.36 V), bromide (E°= 1.09 V) and iodide (E°= 0.536 V) from a thermodynamic perspective under natural conditions, i.e., a temperature range of about 0-30 °C and a pH ranging from about 3 (humic soil layer) to about 8 (sea water). (wikipedia.org)
  • For example, myeloperoxidase (MPO) of neutrophils employs chloride as a substrate and forms hypochlorous acid as the main product ( Klebanoff, 2005 ). (frontiersin.org)
  • Lactoperoxidase (LPO) of milk and salivary peroxidase (SPO) of saliva readily oxidize thiocyanate (SCN − ) and generate hypothiocyanous acid or its conjugate base hypothiocyanite (OSCN − ), the latest being predominant in most physiological fluids ( Chandler and Day, 2012 ). (frontiersin.org)
  • 7. The enzymatic material of claim 5 wherein the peroxidatic peroxidase is lactoperoxidase. (google.com)
  • Glutathione Peroxidase antibody LS-C194677 is an unconjugated mouse monoclonal antibody to human Glutathione Peroxidase (GPX1). (lsbio.com)
  • By using tissue-specific skpo-1 RNAi and immunohistochemical localization with an anti- SKPO-1 antibody, it was determined that the peroxidase is functionally and physically present in the hypodermis. (genetics.org)
  • Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. (drugbank.ca)
  • However, a peroxidase exerts an antimicrobial effect indirectly by catalyzing the transformation of a substrate with low antimicrobial properties into one with high antimicrobial effects ( Klebanoff, 1967 ). (frontiersin.org)
  • In contrast to trospium chloride, brain penetration of oxybutynin is not restricted by the drug efflux carrier P-glycoprotein because oxybutynin is not a P-glycoprotein substrate in vivo . (urotoday.com)
  • Peroxidase-catalyzed oxidation of (pseudo)halides yields reactive agents which oxidize microorganisms, damaging essential structural and functional components and causing inhibition of microbial metabolism and growth ( Thomas and Fishman, 1986 ). (frontiersin.org)
  • The peroxidase-catalyzed oxidation of I − yields molecular iodine (I 2 ) and, depending on I − concentration and pH, hypoiodous acid and hypoiodite (OI − ), or else, other iodine species may be present ( Kussendrager and van Hooijdonk, 2000 ). (frontiersin.org)
  • 13. The enzymatic material of claim 5 which also contains, per gram of material, from about 0.0001to about 0.01 millimole of a metal salt of an oxygen accepting anion selected from the group consisting of thiocyanate, chloride and iodine or mixtures of such salts. (google.com)
  • This study was conducted to investigate the effect of Zinc Chloride on streptozotocin-induced diabetic nephropathy in rats compared to Gliclazide, a reference antidiabetic agent. (scirp.org)
  • Effects of Berberine chloride on the liver of streptozotocin-induced diabetes in albino Wistar rats. (greenmedinfo.com)
  • Finally, Zinc Chloride was able to boost the antioxidant defenses of the kidney by increasing the reduced glutathione content and decreasing lipid peroxides content in addition to significantly decreasing kidney nitric oxide content compared to diabetic control rats. (scirp.org)
  • The administration of berberine chloride notably recovered the liver from hyperglycemia induced antioxidant imbalance, inflammation and apoptosis. (greenmedinfo.com)
  • The SKPO-1 protein contains the critical catalytic residues necessary for peroxidase activity, and in a whole animal assay, more H 2 O 2 was detected from the mutant compared to the wild type, consistent with the loss of an H 2 O 2 sink. (genetics.org)
  • Chloride ions have important physiological roles. (hmdb.ca)
  • The following study showed that the administration of mercury in the form of mercuric chloride causes significant alterations in copper and zinc metabolism, but does not seem to affect iron metabolism. (ithyroid.com)
  • Effect of astaxanthin on kidney function impairment and oxidative stress induced by mercuric chloride in rats. (unboundmedicine.com)
  • Mercuric chloride (HgCl2), additionally, is known to debilitate the function of other organelles such as lysosomes that hold transmembrane proton gradient. (naturalnews.com)
  • The amount of chloride in the blood is carefully controlled by the kidneys. (hmdb.ca)
  • 5. The enzymatic material of claim 1 which also contains from about 0.1 to about 10,000 International Units of peroxidatic peroxidase per gram of material. (google.com)
  • CAT also acts as a peroxidase, but its 'peroxidatic' activity also called 'peroxidatic' reaction is relatively slow and noticeable at low H 2 O 2 concentration. (media.pl)
  • This study was performed to compare tissue distribution and brain penetration of the anticholinergic drugs trospium chloride and oxybutynin in a mouse model. (urotoday.com)
  • The purposes of the present study were to: (1) compare tissue distribution of trospium chloride versus oxybutynin, and (2) analyze brain penetration and drug excretion of oxybutynin in P-gp deficient knockout mice. (urotoday.com)
  • Peroxidase-conjugated goat IgG fraction to human IgG Fc is used in immunostaining of acetone-fixed frozen and formalin-fixed, paraffin-embedded tissue sections. (mpbio.com)
  • As a model, we used human SH-SY5Y neuroblastoma cells after treatment with the hypoxia-mimetic cobalt chloride and analyzed differences in the gene expression profiles in comparison to untreated cells. (thisisms.com)
  • Five genes were found to be strongly up-regulated in SH-SY5Y cells after treatment with cobalt chloride: clusterin, glutathione peroxidase 3, insulin-like growth factor 2, solute carrier family 7 member 11, and neural precursor cell expressed developmentally down-regulated protein 9. (thisisms.com)
  • The chloride ion is an essential anion that the body needs for many critical functions. (hmdb.ca)
  • In addition to the data part, the report also provides overview of 4-ethoxybenzoyl chloride market, including classification, application, manufacturing technology, industry chain analysis and latest market dynamics. (absolutereports.com)