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Chlamydophila pneumoniaeChlamydia InfectionsChlamydophila InfectionsChlamydiaChlamydia trachomatisMycoplasma pneumoniaeKlebsiella pneumoniaeStreptococcus pneumoniaeAntibodies, BacterialChlamydophila psittaciPneumonia, BacterialPneumonia, MycoplasmaAzithromycinDNA, BacterialChlamydia muridarumPolymerase Chain ReactionArteriosclerosisImmunoglobulin AAnti-Bacterial AgentsChaperonin 60Immunoglobulin GKlebsiella InfectionsPsittacosisPneumococcal InfectionsAntigens, BacterialSerologic TestsBacterial ProteinsPhascolarctidaeBacterial Outer Membrane ProteinsMicrobial Sensitivity TestsRespiratory Tract InfectionsChlamydiaceae InfectionsSeroepidemiologic StudiesRoxithromycinChlamydiaceaeChlamydial PneumoniaNasopharynxLymphogranuloma VenereumAnti-Infective AgentsInclusion BodiesErythromycinCommunity-Acquired InfectionsFluoroquinolonesMacrolidesKetolidesDEAE-DextranOfloxacinPneumonia, PneumococcalDoxycyclineFluorescent Antibody TechniqueGenes, BacterialFluorescent Antibody Technique, DirectMolecular Sequence DataGonorrheaGenital Diseases, FemaleBacteriological TechniquesFemale Urogenital DiseasesLungRisk FactorsPneumoniaSensitivity and SpecificityUterine CervicitisNaphthyridinesUrethritisPrevalenceMale Urogenital DiseasesPharynxQuinolonesImmunoglobulin MEnzyme-Linked Immunosorbent AssayAcute DiseasePelvic Inflammatory DiseaseChronic DiseaseDrug Resistance, BacterialCarotid Artery DiseasesCase-Control StudiesCoronary Artery DiseaseEvaluation Studies as Topicbeta-LactamasesRNA, BacterialSerotypingBase SequenceChlamydialesSpecies SpecificitySputumProspective StudiesAortitisC-Reactive ProteinLevofloxacinHeLa CellsTrachomaCoronary DiseaseSexually Transmitted Diseases, BacterialCarotid ArteriesAza CompoundsPenicillin ResistanceClarithromycinUrethraCervix UteriImmunoenzyme Techniques
ChlamydophilaMycoplasmaTrachomatisStreptococcusBacteriaIntracellularAtherosclerosisPathogenesisInfectionsPathogenInfection in patientsStrainsAtheroscleroticBacterialAcuteSeropositivityAntigensVitroConclusionsClinicalAntibodiesOrganismMonocytes2023PatientsAlzheimer'sProteinSerumGenomeInfluenzaeConjunctivitisAsthmatic bronchitisSputumAsthmaCommon
Chlamydophila1
Mycoplasma7
Trachomatis13
  • In vitro activities of BMS-284756 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae. (suny.edu)
  • Malay S, Roblin PM, Reznik T, Kutlin A, Hammerschlag MR. In vitro activities of BMS-284756 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae. (suny.edu)
  • The in vitro activities of BMS-284756 (a novel des-fluoroquinolone), levofloxacin, moxifloxacin, and clarithromycin were tested against 5 strains of Chlamydia trachomatis and 20 isolates of Chlamydia pneumoniae. (suny.edu)
  • The MIC at which 90% of the isolates were inhibited and the minimal bactericidal concentration at which 90% of the isolates were killed by BMS-284756 for all isolates of C. pneumoniae and C. trachomatis was 0.015 microg/ml (range, 0.015 to 0.03 microg/ml). (suny.edu)
  • In vitro activity of nemonoxacin, a novel nonfluorinated quinolone antibiotic, against Chlamydia trachomatis and Chlamydia pneumoniae. (suny.edu)
  • In-vitro activity of gatifloxacin against Chlamydia trachomatis and Chlamydia pneumoniae. (suny.edu)
  • Positive Serology for Chlamydia: Is It Always for Chlamydia trachomatis? (karger.com)
  • In this study we tried to determine the factual prevalence of Chlamydia trachomatis seropositive women. (karger.com)
  • The SPEIA test identified 41 (33.6%) of those as positive for C. trachomatis and 81 (66.4%) positive for C. pneumoniae . (karger.com)
  • We conclude that the currently used IPA method for chlamydia diagnosis overestimates C. trachomatis infection and its specificity for the diagnosis of C. trachomatis is limited. (karger.com)
  • By using the SPEIA test, it is possible to distinguish between C. trachomatis and C. pneumoniae seropositivity. (karger.com)
  • Trachoma Trachoma is a chronic conjunctivitis caused by Chlamydia trachomatis and is characterized by progressive exacerbations and remissions. (msdmanuals.com)
  • Lymphogranuloma Venereum (LGV) Lymphogranuloma venereum (LGV) is a disease caused by 3 unique strains of Chlamydia trachomatis and characterized by a small, often asymptomatic skin lesion, followed by regional lymphadenopathy. (msdmanuals.com)
Streptococcus4
Bacteria3
  • Check out relevant papers found by Labettor's AI that are relevant for performing Protein isolation Bacteria - Chlamydia pneumoniae using Trichloroacetic acid from Sigma-Aldrich. (labettor.com)
  • The Chlamydia pneumoniae IgM test is used to detect the presence of antibodies against chlamydia bacteria indicating active or previous infection. (redcliffelabs.com)
  • Chlamydiae are nonmotile, obligate intracellular bacteria. (msdmanuals.com)
Intracellular3
  • Chlamydia pneumoniae is a species of Chlamydia, an obligate intracellular bacterium that infects humans and is a major cause of pneumonia. (wikipedia.org)
  • C. pneumoniae is an obligate intracellular Gram-negative bacterium. (hopkinsguides.com)
  • Objectives: Our laboratory has been studying the role of infection with the obligate intracellular bacterium Chlamydia pneumoniae in sporadic late-onset Alzheimer disease (LOAD). (pcom.edu)
Atherosclerosis3
  • In research into the association between C. pneumoniae infection and atherosclerosis and coronary artery disease, serological testing, direct pathologic analysis of plaques, and in vitro testing suggest infection with C. pneumoniae is a significant risk factor for development of atherosclerotic plaques and atherosclerosis. (wikipedia.org)
  • We are sure that the original observations of C. pneumoniae in atherosclerosis were received skeptically, but this organism is now being fully investigated for its role in that disease. (alzforum.org)
  • Chlamydia pneumoniae is a chronic infection that can lead to severe health conditions such as arthritis, asthma, and atherosclerosis. (redcliffelabs.com)
Pathogenesis4
  • The fundamental question is what role C. pneumoniae plays in the pathogenesis of Alzheimer's disease. (alzforum.org)
  • The role of Chlamydia pneumoniae infection in pathogenesis and prognostic stratification of patients with acute coronary syndromes is still unclear. (unich.it)
  • These gene changes appear to correlate with pathologic changes previously reported in AD and further support the contention that infection with Chlamydia pneumoniae plays a role in LOAD pathogenesis. (pcom.edu)
  • This investigation was aimed at dissecting the mechanisms of C. pneumoniae pathogenesis by multivariate analysis of challenge experiments in a mouse model of C. pneumoniae lung infection. (auburn.edu)
Infections5
  • Quarterly rates of M. pneumoniae -positive samples ranged from 1.5% to 27.3%, showing a strong epidemic peak for these infections, but of Chlamydia spp. (cdc.gov)
  • Reports from Europe and Asia have shown a notable increase in the frequency of infections caused by M. pneumoniae during 2011-2012 ( 5 - 12 ). (cdc.gov)
  • The chlamydia-pneumonia-IgM-antibodies detect the presence of respiratory tract infections like pneumonia. (redcliffelabs.com)
  • Chlamydial infections, proceedings of the ninth international symposium on human chlamydia infection (pp. 17-17). (eur.nl)
  • Three species of Chlamydia cause human disease, including sexually transmitted infections and respiratory infections. (msdmanuals.com)
Pathogen3
  • The most common bacterial pathogen overall is S pneumoniae , although, in some settings, including in the United States, its incidence is decreasing, possibly owing to vaccination. (medscape.com)
  • Infection with Chlamydia pneumoniae , a common human respiratory pathogen, has recently been associated with cardiovascular syndromes, such as AAA, myocardial infarction and stroke. (viamedica.pl)
  • S. pneumoniae is the most common bacterial pathogen of community acquired pneumonia in childhood. (nature.com)
Infection in patients1
  • One meta-analysis of serological data comparing prior C. pneumoniae infection in patients with and without lung cancer found results suggesting prior infection was associated with an increased risk of developing lung cancer. (wikipedia.org)
Strains2
  • For clarification of the epidemiology of M. pneumoniae infection and identification of the relevant periods of incidence peaks, molecular typing of the prevalent strains can be an efficient tool. (cdc.gov)
  • M. pneumoniae strains can be divided into subtypes and variants according to sequence differences in the gene coding for the immunodominant main adhesin P1. (cdc.gov)
Atherosclerotic1
  • However, most current research and data are insufficient and do not define how often C. pneumoniae is found in atherosclerotic or normal vascular tissue. (wikipedia.org)
Bacterial1
  • The term "typical" CAP refers to a bacterial pneumonia caused by pathogens such as S pneumoniae , H influenzae , and M catarrhalis . (medscape.com)
Acute8
  • C. pneumoniae infection triggers acute wheezing, if it becomes chronic then it is diagnosed as asthma. (wikipedia.org)
  • These observations suggest that acute C. pneumoniae infection is capable of causing protean manifestations of chronic respiratory illness which lead to asthma. (wikipedia.org)
  • Association of acute C pneumoniae infection with signs and symptoms of respiratory illness and the relationship of C pneumoniae antibody titer with wheezing at the time of enrollment in the study, and with the diagnosis of asthmatic bronchitis. (nih.gov)
  • Nine (47%) of 19 patients with acute C pneumoniae infection had bronchospasm during respiratory illness, and there was a strong quantitative association of C pneumoniae titer with wheezing at the time of enrollment in the study (P = .01). (nih.gov)
  • Some C pneumoniae antibody titers, although not diagnostic of chlamydial infection by present criteria, probably represent acute reinfection or ongoing chronic infection. (nih.gov)
  • Acute Chlamydia pneumoniae infection causes coronary endothelial dysfunction in pigs. (lu.se)
  • Dive into the research topics of 'Acute Chlamydia pneumoniae infection causes coronary endothelial dysfunction in pigs. (lu.se)
  • Our data indicate that elevated titers of C. pneumoniae antibodies, even with a serial 1-year evaluation, are not a predictor of future coronary events in patients with acute myocardial infarction or unstable angina. (unich.it)
Seropositivity1
  • No strong associations were observed of these factors with Helicobacter pylori seropositivity, Chlamydia pneumoniae IgG titres, or plasma total homocysteine concentrations. (bmj.com)
Antigens1
  • We are confident that organisms containing genetic sequences and expressing C. pneumoniae -related antigens were present in the samples examined by our group. (alzforum.org)
Vitro5
  • C. pneumoniae infection increases adherence of macrophages to endothelial cells in vitro and aortas ex vivo. (wikipedia.org)
  • In vitro activity of garenoxacin against recent clinical isolates of Chlamydia pneumoniae. (suny.edu)
  • Comparative in vitro activity of garenoxacin against Chlamydia spp. (suny.edu)
  • In vitro activities of gemifloxacin (SB 265805, LB20304) against recent clinical isolates of Chlamydia pneumoniae. (suny.edu)
  • Methods: Human SKNMC neuronal cells and THP1 monocytes were infected in vitro for 24-72 hrs with a laboratory strain of Chlamydia pneumoniae followed by RNA extraction, cDNA synthesis and analysis using Real-Time PCR microarrays for autophagy and inflammasome genes. (pcom.edu)
Conclusions1
  • Conclusions: Our data suggest that Chlamydia pneumoniae-infected human SKNMC neuronal cells and THP1 monocytes exhibit specific changes in gene regulation for both autophagy and inflammasome pathways. (pcom.edu)
Clinical3
  • This letter is in response to the recent article in Journal of Clinical Microbiology (38[2]:881-882, 2000) entitled 'Failure to detect Chlamydia pneumoniae in brain sections of Alzheimer's Disease Patients' by Gieffers et al. (alzforum.org)
  • For this reason and because of the body of literature from hundreds of different Chlamydia studies that demonstrate a tremendous variability in diagnosing, identifying, and localizing Chlamydia in clinical specimens, we went to the extreme in our investigations by using a large variety of techniques on different clinical specimens. (alzforum.org)
  • OBJECTIVE--To study the clinical characteristics of respiratory tract illness caused by Chlamydia pneumoniae. (nih.gov)
Antibodies3
  • The Chlamydia Pneumoniae IgM Antibodies test is used to detect the Chlamydia pneumoniae infection in the blood. (redcliffelabs.com)
  • The microimmunofluorescence test was used to detect C. pneumoniae specific antibodies. (unich.it)
  • No significant difference was found between patients with (n = 35) or without (n = 79) new coronary events (N.C.E.) regarding baseline and serial values of C. pneumoniae antibodies. (unich.it)
Organism1
  • Subsequent studies of bronchoalveolar lavage fluid from pediatric patients with asthma and also other severe chronic respiratory illnesses have demonstrated that over 50 percent had evidence of C. pneumoniae by direct organism identification. (wikipedia.org)
Monocytes1
20231
  • 2023. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540117/all/Chlamydia_pneumoniae. (hopkinsguides.com)
Patients8
  • Chlamydia pneumoniae has also been found in the cerebrospinal fluid of patients diagnosed with multiple sclerosis. (wikipedia.org)
  • M. pneumoniae -positive patients were younger and more frequently female, had fewer co-occurring conditions, and experienced milder disease than did patients who tested negative. (cdc.gov)
  • Secondarily, a matched comparison of patients with and without evidence of C pneumoniae infection (serologic titers greater than or equal to 1:64 and less than 1:16, respectively). (nih.gov)
  • According to the literature data, a significantly high percentage of patients with cardiovascular diseases exhibited serological markers of chronic C. pneumoniae infection. (viamedica.pl)
  • The aim of our study was to evaluate the frequency of C. pneumoniae infection in CHD, CAD and AAA patients by measuring specific serum IgG, IgM and IgA levels. (viamedica.pl)
  • Serological markers of chronic C. pneumoniae infection were detected in 37/47 (80.9%) CHD patients, in 12/17 (70.6%) CAD patients, in 25/28 (89.3%) AAA patients and in 6/20 (30%) healthy controls. (viamedica.pl)
  • Serological signs of chronic C. pneumoniae infection occur statistically more frequently in CHD, CAD and AAA patients in comparison with healthy controls. (viamedica.pl)
  • In some patients with C. pneumoniae , pneumonia, hoarseness, and sore throat may precede coughing, which may be persistent and complicated by bronchospasm. (msdmanuals.com)
Alzheimer's2
  • Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain. (alzforum.org)
  • used similar protocols as did Gieffers et al and also failed to detect C. pneumoniae in the Alzheimer's brain. (alzforum.org)
Protein1
  • Researchers designed and evaluated a multi-epitope vaccine targeting the main outer membrane protein of Chlamydia pneumoniae using immunoinformatics. (news-medical.net)
Serum4
  • Description Chlamydia pneumoniae IgG Control Serum (C1371G) are positive controls for immunoassays of the SERION ELISA classic product line and are obtained from the material of individual human donors. (qedbio.com)
  • We stated that serum vitamin A levels in neonatal S. pneumoniae pneumonia mice were lower than 0.7µmol/L from day 2-7 post infection, while pulmonary vitamin A productions were significantly lower than those in the control mice from day 7-28 post infection. (nature.com)
  • Our data suggest that neonatal S. pneumoniae pneumonia induce serum vitamin A deficiency and long-time lung vitamin A reduction, vitamin A supplement after neonatal S. pneumoniae pneumonia inhibit the progression of asthma by altering CD4 + T cell subsets. (nature.com)
  • In this study, we established a neonatal non-lethal S. pneumoniae pneumonia mice model and monitored vitamin A levels in lung, serum and liver until early adulthood. (nature.com)
Genome1
  • The full genome sequence for C. pneumoniae was published in 1999. (wikipedia.org)
Influenzae1
  • Second-generation cephalosporin maintains the gram-positive activity of first-generation cephalosporins and adds activity against Proteus mirabilis, H influenzae, E coli, K pneumoniae, and M catarrhalis . (medscape.com)
Conjunctivitis1
Asthmatic bronchitis2
  • Chlamydia pneumoniae infection was first associated with wheezing, asthmatic bronchitis, and adult-onset asthma in 1991. (wikipedia.org)
  • Repeated or prolonged exposure to C pneumoniae may have a causal association with wheezing, asthmatic bronchitis, and asthma. (nih.gov)
Sputum1
  • Rhinovirus, C pneumoniae , and B pertussis are found in the sputum or pharyngeal swab specimens of asthmatic subjects without concurrent symptoms of infection or asthma exacerbation, as well as in some healthy controls. (bmj.com)
Asthma5
  • Whether neonatal S. pneumoniae pneumonia induced asthma was associated with vitamin A levels remains unclear. (nature.com)
  • The aim of this study was to investigate the effects of neonatal S. pneumoniae pneumonia on vitamin A expressions, to explore the effects of vitamin A supplement after neonatal S. pneumoniae pneumonia on adulthood asthma development. (nature.com)
  • The prevention and treatment of asthma induced by S. pneumoniae pneumonia is crucial, while it remains indistinctly. (nature.com)
  • Whether neonatal S. pneumoniae pneumonia promoted adulthood allergic asthma was associated with vitamin A levels remains unclear. (nature.com)
  • We also explored the effects of vitamin A supplement after neonatal S. pneumoniae pneumonia on the development of adulthood allergic asthma. (nature.com)
Common1