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Anatomy20

Cell Line, Tumor HCT116 Cells HeLa Cells Cell Line Blastula Centrosome Cell Nucleus Fibroblasts HEK293 Cells Chromatin Tumor Cells, Cultured HT29 Cells Cell Line, Transformed Spindle Apparatus Cells, Cultured Cell-Free System Embryo, Nonmammalian Telomere Sf9 Cells Cytoplasm

Organisms6

Schizosaccharomyces Xenopus Mice, Knockout Chickens Saccharomyces cerevisiae Xenopus laevis

Diseases10

Genomic Instability Ataxia Telangiectasia Li-Fraumeni Syndrome Chromosomal Instability Neoplasms Microcephaly Fanconi Anemia Breast Neoplasms Colonic Neoplasms Tetraploidy

Chemicals and Drugs129

Checkpoint Kinase 2 Protein Kinases Ataxia Telangiectasia Mutated Proteins Protein-Serine-Threonine Kinases Cell Cycle Proteins cdc25 Phosphatases Tumor Suppressor Proteins Hydroxyurea Tumor Suppressor Protein p53 Staurosporine DNA-Binding Proteins Protein Kinase Inhibitors RNA, Small Interfering Nuclear Proteins Carbanilides Naphthalimides Schizosaccharomyces pombe Proteins Serine 14-3-3 Proteins Caffeine CDC2 Protein Kinase Thiophenes Histones Aphidicolin Topoisomerase Inhibitors Proto-Oncogene Proteins pp60(c-src)Threonine Camptothecin Alkaloids Replication Protein A Phosphoserine Antineoplastic Agents Topoisomerase I Inhibitors Cyclin B BRCA1 Protein DNA-Activated Protein Kinase Xenopus Proteins Cyclin B1 Protein-Tyrosine Kinases Adaptor Proteins, Signal Transducing Enzyme Inhibitors Nucleic Acid Synthesis Inhibitors 1-Naphthylamine Poly(ADP-ribose) Polymerases DNA Cyclin-Dependent Kinase Inhibitor p21 Rad51 Recombinase Cyclin-Dependent Kinase 2 Radiation-Sensitizing Agents Chromatin Intracellular Signaling Peptides and Proteins Urea Oligoribonucleotides, Antisense Pyrazoles Nocodazole Phosphoprotein Phosphatases Methyl Methanesulfonate Pyrimidines Phosphothreonine ras-GRF1 Enediynes Recombinant Proteins Securin Quinuclidines Fanconi Anemia Complementation Group D2 Protein Deoxycytidine beta-Synuclein HSP90 Heat-Shock Proteins src-Family Kinases Proliferating Cell Nuclear Antigen Benzodioxoles Recombinant Fusion Proteins DNA Repair Enzymes Lactams, Macrocyclic Cisplatin Ubiquitin Chromosomal Proteins, Non-Histone Benzoquinones Fungal Proteins Biomarkers, Pharmacological E2F1 Transcription Factor beta-Transducin Repeat-Containing Proteins Benzodiazepinones Antimetabolites, Antineoplastic DNA Helicases SKP Cullin F-Box Protein Ligases Carbazoles Benzimidazoles Saccharomyces cerevisiae Proteins Thioguanine Etoposide Glutathione Transferase Caspase 2 Cyclin-Dependent Kinases Antineoplastic Agents, Alkylating Carrier Proteins Minichromosome Maintenance Complex Component 2 Ubiquitin-Protein Ligases Aurora Kinases Kinetin Telomeric Repeat Binding Protein 2 Antineoplastic Agents, Phytogenic Aurora Kinase B Allyl Compounds Topotecan Proto-Oncogene Proteins Heterocyclic Compounds, 3-Ring Protein Phosphatase 2 MAP Kinase Kinase 2 DNA, Fungal DNA, Single-Stranded MAP Kinase Kinase 1 Proto-Oncogene Proteins c-mdm2 Antibiotics, Antineoplastic Antigens, Nuclear Tyrosine 3-Monooxygenase Choline Kinase Cyclin A Doxorubicin Topoisomerase II Inhibitors Cyclin E Mutant Proteins Transcription Factors Zinostatin Mad2 Proteins Proteasome Endopeptidase Complex Caspase 7 Exonucleases Multiprotein Complexes

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Models, Biological Blotting, Western Immunoblotting Immunoprecipitation Flow Cytometry Transfection Gene Knockdown Techniques Laser Scanning Cytometry Comet Assay Dose-Response Relationship, Radiation Precipitin Tests Gene Targeting Xenograft Model Antitumor Assays Microscopy, Fluorescence Inhibitory Concentration 50 Amino Acid Substitution Mutagenesis, Site-Directed Fluorescent Antibody Technique Drug Screening Assays, Antitumor Fluorescence Polarization Immunoassay

Phenomena and Processes76

DNA Damage G2 Phase Phosphorylation Cell Cycle Radiation, Ionizing S Phase DNA Replication Cell Cycle Checkpoints Genes, cdc Mitosis DNA Repair G2 Phase Cell Cycle Checkpoints Enzyme Activation Signal Transduction Ultraviolet Rays Mutation Apoptosis Gamma Rays RNA Interference S Phase Cell Cycle Checkpoints DNA Breaks, Double-Stranded Protein Binding Radiation Tolerance Genomic Instability M Phase Cell Cycle Checkpoints Cell Survival Amino Acid Sequence Protein Structure, Tertiary G1 Phase Ubiquitination Catalytic Domain Drug Agonism Amino Acid Motifs Cell Death Chromosomal Instability Chromatin Down-Regulation Genes, p53 Cell Division Recombinational DNA Repair Transfection DNA Breaks Gene Deletion Cell Aging Cell Proliferation Dose-Response Relationship, Radiation Gene Expression Regulation, Neoplastic Drug Synergism Prometaphase X-Rays Time Factors Homologous Recombination DNA Mismatch Repair Gene Expression Regulation, Enzymologic Replication Origin Binding Sites Inhibitory Concentration 50 Amino Acid Substitution Radiation Stress, Physiological Anaphase DNA, Single-Stranded Dose-Response Relationship, Drug Gene Expression Regulation Sequence Homology, Amino Acid Protein Processing, Post-Translational Base Pair Mismatch Gene Silencing Gene Expression Regulation, Fungal Phenotype Tetraploidy src Homology Domains Base Sequence DNA Breaks, Single-Stranded Telomere Infrared Rays

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care3

Ultraviolet Rays Dose-Response Relationship, Radiation Infrared Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science Health Care

Checkpoint Kinase 2 Protein Kinases Ataxia Telangiectasia Mutated Proteins DNA Damage Protein-Serine-Threonine Kinases Cell Cycle Proteins cdc25 Phosphatases G2 Phase Phosphorylation Cell Cycle Radiation, Ionizing Tumor Suppressor Proteins S Phase DNA Replication Hydroxyurea Cell Cycle Checkpoints Tumor Suppressor Protein p53 Staurosporine DNA-Binding Proteins Cell Line, Tumor Genes, cdc Mitosis Protein Kinase Inhibitors DNA Repair RNA, Small Interfering G2 Phase Cell Cycle Checkpoints Nuclear Proteins HCT116 Cells Schizosaccharomyces Carbanilides HeLa Cells Enzyme Activation Naphthalimides Signal Transduction Ultraviolet Rays Mutation Schizosaccharomyces pombe Proteins Serine Apoptosis 14-3-3 Proteins Caffeine CDC2 Protein Kinase Thiophenes Gamma Rays RNA Interference S Phase Cell Cycle Checkpoints DNA Breaks, Double-Stranded Histones Cell Line Aphidicolin Blastula Topoisomerase Inhibitors Protein Binding Proto-Oncogene Proteins pp60(c-src)Threonine Camptothecin Radiation Tolerance Alkaloids Replication Protein A Phosphoserine Models, Biological Genomic Instability M Phase Cell Cycle Checkpoints Antineoplastic Agents Blotting, Western Topoisomerase I Inhibitors Cyclin B BRCA1 Protein Cell Survival Immunoblotting DNA-Activated Protein Kinase Molecular Sequence Data Amino Acid Sequence Protein Structure, Tertiary Xenopus Proteins Cyclin B1 Protein-Tyrosine Kinases Adaptor Proteins, Signal Transducing Centrosome Enzyme Inhibitors Cell Nucleus Nucleic Acid Synthesis Inhibitors 1-Naphthylamine Poly(ADP-ribose) Polymerases Ataxia Telangiectasia Fibroblasts G1 Phase DNA Ubiquitination Immunoprecipitation Catalytic Domain Drug Agonism Amino Acid Motifs Li-Fraumeni Syndrome Cyclin-Dependent Kinase Inhibitor p21 Cell Death HEK293 Cells Rad51 Recombinase Cyclin-Dependent Kinase 2 Chromosomal Instability

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