• Isolation of chikungunya virus from Aedes aegypti mosquitoes collected in the town of Yawat, Pune District, Maharashtra State, India. (ajtmh.org)
  • The southern saltmarsh mosquito (Aedes camptorhynchus), which is known to carry the Ross River virus, was discovered in Napier, New Zealand, in 1998. (wikipedia.org)
  • In recent years, mosquito species Aedes albopictus has expanded in the Indian Ocean region and was the principal vector of chikungunya outbreaks in La Reunion and neighbouring islands in 2005 and 2006. (datadryad.org)
  • Aedes albopictus is a mosquito that has taken advantage of human activities to extend its territory and be linked to the emergence of arbovirus of which it is the vector. (pasteur.fr)
  • The "Aedes Invasive Mosquitoes" (AIM) COST Action Program has received four years of funding to develop synergies between scientists and public health professionals to deal with invasive mosquitoes Aedes that can transmit diseases such as Dengue, Zika, the West Nile virus fever and the Chikungunya. (cresa.cat)
  • Best adapted of all are Aedes aegypti mosquitoes, the cosmopolitan vector of epidemic yellow fever, dengue, chikungunya, and Zika viruses. (cdc.gov)
  • Persistence of human yellow fever, the inexorable expanse of dengue, and the surprising, explosive spread and severity of first chikungunya virus and now Zika virus bear testament to the threat posed by habituated Aedes species. (cdc.gov)
  • The chikungunya pandemic that began 10 years ago was fueled in part by a single, nonsynonymous base change that enabled that alphavirus to replicate more efficiently in Aedes albopictus mosquitoes. (cdc.gov)
  • The virus has spread worldwide due to the ecology of its vectors ( Aedes aegypti and Aedes albopictus ). (news-medical.net)
  • High-Throughput Method for Detection of Arbovirus Infection of Saliva in Mosquitoes Aedes aegypti and Ae. (fiocruz.br)
  • Chikungunya disease is transmitted by the Aedes mosquito. (merckmanuals.com)
  • Tête de moustique femelle Aedes albopictus, vecteur du virus de la dengue et du chikungunya. (pasteur.fr)
  • Since 2005, cases of chikungunya (CHIK) were caused by an unusual vector, Aedes albopictus. (pasteur.fr)
  • The Fellow will participate in field investigations on establishing what are the minimum numbers of Aedes aegypti mosquitoes required to prevent rampant outbreaks of arboviruses such as dengue (DENVs), chikungunya (CHIKV), Zika (ZIKV), or yellow fever (YFV) viruses. (berkeley.edu)
  • Currently, the only way to control or prevent the transmission of the virus is the fight against Aedes aegypti, the main mosquito vector. (sanpedrosun.com)
  • Dengue is caused by dengue virus (DENV), a virus which can be transmitted by Aedes mosquitos. (pasteur-kh.org)
  • Evaluación de la resistencia a insecticidas en cepas de Aedes aegypti (Diptera: Culicidae) de la Región Caribe de Costa Rica. (una.ac.cr)
  • Perfil de resistencia a insecticidas en una cepa de Aedes aegypti (Linnaeus) de la región Caribe de Costa Rica. (una.ac.cr)
  • Vertical transmission in Aedes aegypti and Aedes albopictus is considered a maintenance mechanism for dengue virus (DENV) during unfavorable conditions and may be implicated in dengue outbreaks. (nature.com)
  • 2016. Differential susceptibilities of Aedes aegypti and Aedes albopictus from the Americas to Zika virus. (innspub.net)
  • 2017. Vertical transmission of Zika virus by Aedes aegypti and Ae. (innspub.net)
  • Quais as intervenções mais efetivas para o controle do vetor Aedes Aegypti no ambiente urbano nos diferentes contextos brasileiros, considerando o aumento da incidência de casos de microcefalia possivelmente relacionada ao Zika Virus. (bvsalud.org)
  • Arbovirus infection of Aedes aegypti salivary glands (SGs) determines transmission. (pasteur.fr)
  • The global distribution of the arbovirus vectors Aedes aegypti and Ae. (medscape.com)
  • Dengue and chikungunya in our backyard: preventing Aedes mosquito-borne diseases. (medscape.com)
  • The term "Chikungunya" often refers to both the virus (CHIKV) and the illness or fever (CHIKF) caused by this virus. (medscape.com)
  • Seroprevalence of Chikungunya Virus (CHIKV) Infection on Lamu Island, Kenya, October 2004. (ajtmh.org)
  • Mosquitoes transmit numerous arboviruses including dengue and chikungunya virus (CHIKV). (datadryad.org)
  • albopictus highlighting the co-ancestry of the different derived populations and the dissemination and transmission efficiencies for Chikungunya virus (CHIKV). (pasteur.fr)
  • Some arboviruses, like dengue (DENV), chikungunya (CHIKV) and Zika (ZIKV), have become fully adapted to urban cycles and no longer require NHPs, forest mosquitoes and a sylvatic cycle for their maintenance [ 7 ]. (biomedcentral.com)
  • Chikungunya (CHIKV) and Zika (ZIKV) viruses are two arboviruses which have recently broken their sylvatic isolation and gone into a rampant spreading among humans in some urban areas of the world, specially in Latin America. (biorxiv.org)
  • Given the huge burden that Chikungunya and Zika fevers impose to public health in the affected countries and the lack of effective interventions against them, the aim of this work was to evaluate the antiviral potential of bovine lactoferrin (bLf) - an iron-binding glycoprotein with broad-spectrum antimicrobial properties - in both CHIKV and ZIKV infections. (biorxiv.org)
  • Results obtained in this study suggest that the local transmission of four arboviruses - dengue (DENV), chikungunya (CHIKV), zika (ZIKV) and yellow fever (YFV) viruses - by Ae . (tghn.org)
  • In Brazil, the virus that stand out are the Dengue virus (DENV), Chikungunya virus (CHIKV) and Zika virus (ZIKV), the last two first identified in 2014 and 2015 respectively, causing severe Public Health problems, especially in the Northeast region of Brazil. (fapesp.br)
  • In this context, this study aims to understand the dynamics of urban spread of emerging and re-emerging arbovirus (DENV, ZIKV and CHIKV) in the Northeast and Southeast regions of Brazil (states of Sergipe and São Paulo), and identify the demographics and socioeconomic factors associated with the dynamics of viral movement that can provide new opportunities for control and intervention strategies. (fapesp.br)
  • Abstract Background The emerging chikungunya virus (CHIKV), is an arbovirus causing intense outbreaks in North America. (uanl.mx)
  • In addition to the clinical examination, real-time polymerase chain reaction (PCR) standardized for the Asian Chikungunya lineage and/or enzyme-linked immunosorbent assay for immunoglobulin M (IgM) were used to confirm CHIKV diagnosis. (uanl.mx)
  • Chikungunya virus infection has a clinical presentation that overlaps with that of Ross River virus infection (fever, rash, polyarthritis) and dengue fever transmitted by the same mosquitoes. (medscape.com)
  • Arthropod-borne viruses (arboviruses) are transmitted to humans primarily through the bites of infected mosquitoes or ticks, and in the continental United States, West Nile virus (WNV) is the leading cause of domestically acquired arboviral disease. (medscape.com)
  • In July and August 1956 and 1957, a virus recovered from mosquitoes collected near Tokyo, Japan, and was dubbed Sagiyama virus. (wikipedia.org)
  • Chikungunya: the specific interactions between the genotypes of mosquitoes and viruses have influenced Ae. (pasteur.fr)
  • Thus, the specific interactions between the genotypes of mosquitoes and viruses have influenced Ae. (pasteur.fr)
  • While the risk of importation is equally high in all countries in the Region, the risk of local transmission following introduction of the virus through a viraemic patient returning from countries with active Zika virus circulation remains high in areas where the mosquitoes that primarily transmit this virus exist. (who.int)
  • Arbovirus" is a descriptive term applied to hundreds of predominantly RNA viruses that are transmitted by arthropods, most notably through mosquitoes. (prnewswire.com)
  • Arboviruses infecting people primarily exist in urban transmission cycles involving urban mosquitoes in densely populated tropical regions. (biomedcentral.com)
  • For dengue, chikungunya, Zika and yellow fever viruses, sylvatic (forest) transmission cycles also exist in some regions and involve non-human primates and forest-dwelling mosquitoes. (biomedcentral.com)
  • In the natural forest habitats of the NHPs, arboreal mosquitoes transmit arboviruses from infected to naïve animals in what is termed a sylvatic transmission cycle (NHP-mosquito-NHP-mosquito, etc. (biomedcentral.com)
  • People can become infected if they encroach on forest habitat (either through deforestation, hunting, agriculture, or urbanization) and are fed upon by mosquitoes carrying arboviruses, or if infected forest mosquitoes move into areas of human habitation to obtain a blood meal. (biomedcentral.com)
  • When humans infected in the forest enter urban environments, arbovirus infections can rapidly spread amongst people transmitted by highly anthrophilic, urban mosquitoes. (biomedcentral.com)
  • Dengue and Zika viruses are transmitted by the same mosquitoes and have similar clinical features as chikungunya disease and should be considered ( Centers for Disease Control and Prevention (CDC): Chikungunya Virus ). (merckmanuals.com)
  • The Unit has also made progress towards understanding the dynamics of arboviruses in mosquito populations in the context of defining mosquito density thresholds that are necessary for arbovirus transmission and how incidence of arboviruses in mosquitoes relate to human infections. (berkeley.edu)
  • aegypti mosquitoes in urban communities by mass mosquito trapping and for long enough to be able to detect differences in arbovirus prevalence in mosquitoes. (berkeley.edu)
  • arthropod-borne virus) applies to any virus that is transmitted to humans and/or other vertebrates by certain species of blood-feeding arthropods, chiefly insects (flies and mosquitoes) and arachnids (ticks). (msdmanuals.com)
  • like disease transmitted by mosquitoes infected with Mayaro virus. (msdmanuals.com)
  • Although, both mosquitoes were highly susceptible to the virus, Ae. (monash.edu)
  • Humans contract West Nile when they are bitten by mosquitoes infected with the virus. (la.gov)
  • Mosquitoes are insects, feed on blood and transmit pathogenic viruses via biting the particular host. (innspub.net)
  • Chikungunya, Dengue fever, Zika fever and West Nile are most prevalent mosquitoes borne viral diseases in Pakistan. (innspub.net)
  • The microbiota associated with mosquitoes (comprised of viruses, bacteria, fungi and protozoa) can profoundly influence many host phenotypes including vector competence, which can either be enhanced or suppressed. (utmb.edu)
  • Hughes, Grant L. / The microbiome modulates arbovirus transmission in mosquitoes . (utmb.edu)
  • Arthropod-borne viruses (arboviruses) are transmitted to humans primarily through the bites of infected mosquitoes, ticks, sand flies, or midges. (cdc.gov)
  • Renault P , Solet JL , Sissoko D , Balleydier E , Larrieu S , Filleul L , A major epidemic of chikungunya virus infection on Reunion Island, France, 2005-2006. (cdc.gov)
  • Epidemiological alert: neurological syndrome, congenital malformations, and Zika virus infection. (cdc.gov)
  • The recent re-emergence and travel-related spread of Chikungunya infection to Europe and the United States has drawn global attention. (medscape.com)
  • Both natural and Chikungunya virus infection-induced specific antibodies were essential for controlling Chikungunya virus infections. (medscape.com)
  • Chikungunya virus infection elicited strong innate immunity with an abundant production of proinflammatory markers and cytokines, including high levels of alpha interferon, interleukin (IL)-4, IL10, and gamma interferon. (medscape.com)
  • A 2017 study reported that Chikungunya infection activates toll-like receptors (TLR), triggering the innate immune system. (medscape.com)
  • Over 2 million adults in the United States have hepatitis C virus (HCV) infection, and new infections have continued to rise. (cdc.gov)
  • In the US, the most common types of viral hepatitis are hepatitis A, B, and C. While each can produce similar symptoms, each hepatitis virus affects the liver differently, has different routes of transmission and infection, and typically affects different populations. (cdc.gov)
  • Dengue and chikungunya virus infection in man in Thailand, 1962-1964. (ajtmh.org)
  • Chikungunya infection-an emerging disease in Malaysia. (ajtmh.org)
  • Seroprevalence of Chikungunya Virus Infection on Grande Comore Island, Union of the Comoros, 2005. (ajtmh.org)
  • 1) describe the epidemiology, clinical manifestation, management and prevention of Zika virus disease, 2) discuss diagnostic testing for Zika virus infection and interpretation of test results, 3) articulate the importance of early recognition and reporting of cases, 4) state the recommendations for pregnant women and possible Zika virus exposure, and 5) discuss evaluation of infants with microcephaly and relationship of Zika in microcephaly. (cdc.gov)
  • Following this declaration, the WHO Office for the Eastern Mediterranean Region (EMR) conducted two rounds of emergency meetings with a view of enhancing preparedness and readiness for Zika virus infection and associated conditions, in conjunction with representatives of the ministries of health of 12 countries. (who.int)
  • agree upon priority activities to be implemented by Member States and WHO to enhance preparedness and response capacities to Zika virus infection. (who.int)
  • No human infection from Zika virus has so far been reported from any country in the EMR. (who.int)
  • The current situation does not rule out the possibility of occurrence of Zika virus infection, as travel is likely to contribute to the risk of importation of cases to any country in the Region. (who.int)
  • These molecular based assays are without a doubt the most sensitive and specific ways to identify and monitor a Zika Virus infection. (prweb.com)
  • Researchers have linked Zika virus infection with Guillain-Barre syndrome, a severe neurological disorder that can cause paralysis. (prnewswire.com)
  • Beyond Zika, Dengue, Chikungunya and West Nile virus, the Hemopurifier has also been validated to capture Monkey pox, which serves as models for human Smallpox infection. (prnewswire.com)
  • Many medically important and emergent arboviruses (arthropod-borne viruses) originated in non-human primates (NHPs), which typically show no clinical signs of infection but become viraemic and help maintain the virus in nature [ 1 ]. (biomedcentral.com)
  • Survivors of Ebola virus infection may present late with a spectrum of ocular manifestations, ranging from mild retinal scarring to complete bilateral blindness resulting from tractional retinal detachment, cataract and glaucoma secondary to intraocular inflammation. (cehjournal.org)
  • 2 Moreover, in previous outbreaks, Ebola virus infection had been noted to precipitate uveitis in a minority of survivors. (cehjournal.org)
  • The role of antiviral drugs in eliminating intraocular infection with Ebola virus is currently being evaluated. (cehjournal.org)
  • Our data show that bLf exerts a dose-dependent strong inhibitory effect on the infection of Vero cells by the aforementioned arboviruses, reducing their infection efficiency in up to nearly 80%, with no significant cytotoxicity, and such antiviral activity occurs at the levels of binding and replication of the virus particles. (biorxiv.org)
  • It is important to rule out dengue virus infection, because proper clinical management of dengue can improve outcome. (merckmanuals.com)
  • My group apply the techniques of elecrton-cryomicroscopy and image analysis to the study of viruses, providing an exciting opportunity to visualise the process of virus infection at cellular scale and at macromoleculr resolution. (gla.ac.uk)
  • Many human viruses utilise or suppress ubiquitin and ubiquitin-like pathways during infection, enhancing their replication. (gla.ac.uk)
  • We explore the intricate structural interactions between viruses and host complexes during virus infection and immune response, which is crucial for exploiting them and uncovering new avenues for the development of therapeutics. (gla.ac.uk)
  • Additionally, they found evidence for infection by heterologous viruses eliciting cross-reactive antibodies. (tghn.org)
  • Among these viruses, we could highlight those belonging to the Flaviviridae and Togaviridae families, which may cause clinical manifestations ranging from asymptomatic infection, acute febrile to disease viral haemorrhagic fever and encephalitis. (fapesp.br)
  • This section also performs primary diagnostic testing for Q fever, a zoonotic infection endemic in Canada, and serology for the detection of antibodies to rabies virus in humans. (canada.ca)
  • Since DENV infection dynamics vary among wild-type viruses and vector populations, vertical transmission rates can also vary between regions. (nature.com)
  • In a study in the journal Nature Communications [1] last year, Lee's team used cryo-ET to reveal how the chikungunya virus invades and delivers its genetic cargo into human cells to initiate a new infection. (nih.gov)
  • While Lee's cryo-ET data revealed stages of the virus entry process and fine structural details of changes to the virus as it enters a cell and starts an infection, it still represented a series of snapshots with missing steps in between. (nih.gov)
  • This basic research continues to make progress, and so do ongoing efforts to develop a chikungunya vaccine [2] and specific treatments that would help give millions of people relief from the aches, pains, and rashes associated with this still-untreatable infection. (nih.gov)
  • The establishment of a virus infection is the result of the pathogen's ability to replicate in a hostile environment generated by the host's immune system. (bvsalud.org)
  • Compared to SARS-CoV-2 interactors, ZIKV-interacting host RNAs tend to be downregulated upon virus infection. (bvsalud.org)
  • We also identify a conserved set of host RNAs that interacts with DENV, ZIKV, and SARS-CoV-2, suggesting that these RNAs are broadly important for RNA virus infection. (bvsalud.org)
  • However, silencing of the Toll and IMD pathway components showed variable effects on SG infection by each virus. (pasteur.fr)
  • Infection by the three viruses increased with depletion of the activator Kayak and decreased with depletion of the negative regulator Puckered. (pasteur.fr)
  • ZIKV infection diagnosis relies on serology-which is challenging due to cross-reactions with other flaviviruses and/or absence or low titer of IgM and IgG antibodies at early phase of infection- virus isolation, which is labor intensive, time consuming and requires appropriate containment. (biomedcentral.com)
  • This assay is a useful tool for detection of ZIKV infection in regions where a number of other clinically indistinguishable arboviruses like dengue or chikungunya co-circulate. (biomedcentral.com)
  • The non-specific clinical presentation can be confused with most other arboviruses particularly dengue and chikungunya virus infection. (biomedcentral.com)
  • Zika virus (ZIKV) infection was a public health emergency of Brazilian national interest until May 2017, due to the sudden increase in newborns with microcephaly and other neurological alterations during the epidemic started in Brazil in November 2015. (bvsalud.org)
  • Yellow fever (YF) is a mosquito-borne infection that is caused by the YF virus and is endemic to Africa and South America. (medscape.com)
  • YF is a mosquito-borne infection that is caused by the YF virus. (medscape.com)
  • Zika virus (ZIKV) is an arbovirus (mosquito-borne), first detected in Uganda in the 1940s. (news-medical.net)
  • RESULTS: Here, we use proximity ligation sequencing to identify virus-host RNA interactions for four strains of Zika virus (ZIKV) and one strain of dengue virus (DENV-1) in human cells. (bvsalud.org)
  • We find hundreds of coding and non-coding RNAs that bind to DENV and ZIKV viruses. (bvsalud.org)
  • In addition, the 3'UTR of DYNLT1 mRNA acts as a virus-restrictive factor by binding to the conserved dumbbell region on DENV and ZIKV 3'UTR to decrease virus replication. (bvsalud.org)
  • Zika virus (ZIKV), a mosquito borne flavivirus is a pathogen affecting humans in Asia and Africa. (biomedcentral.com)
  • Like all flaviviruses, ZIKV is a single-stranded RNA virus with a positive-polarity RNA genome of approximately 11 kb. (biomedcentral.com)
  • ZIKV, an emerging neglected virus, was first documented in 1947 when it was isolated from a sentinel rhesus monkey stationed on a tree platform in the Zika forest, Uganda [ 12 ]. (biomedcentral.com)
  • Between 1968 and 2002, 606 strains including 10 human ZIKV strains were isolated in Central and West Africa countries and reported by the WHO Collaborating Center for Arbovirus and Viral Hemorrhagic Fever of Pasteur Institute in Dakar [ 20 ]. (biomedcentral.com)
  • The recent increase in reported cases of microcephaly and Guillain-Barre Syndrome potentially associated with Zika virus (ZIKV) has highlighted the urgent need to identify individuals infected with ZIKV. (who.int)
  • Forty-nine states and the District of Columbia reported 3,035 cases of domestic arboviral disease, including those caused by West Nile (2,911), La Crosse (40), Jamestown Canyon (32), Powassan (24), St. Louis encephalitis (17), unspecified California serogroup (six), and eastern equine encephalitis (five) viruses. (medscape.com)
  • Within the continental United States, West Nile virus (WNV) is the leading cause of domestically acquired disease caused by arthropod-borne viruses (arboviruses). (medscape.com)
  • Among the 42 West Nile virus disease cases with AFP, 12 (29%) also had encephalitis or meningitis. (medscape.com)
  • Zika virus is a single-stranded RNA virus in the genus flavivirus, family flaviviridae that is closely related to dengue, yellow fever, Japanese encephalitis and West Nile viruses. (cdc.gov)
  • Zika, dengue, West Nile, and yellow fever viruses can co-circulate, not only among themselves, but possibly with unidentified or poorly characterized flaviviruses. (cdc.gov)
  • Fewer than 20 of the 86 known pathogenic arboviruses can be considered major causes of human disease, and 3 of these, West Nile, chikungunya, and Zika viruses, have emerged from relative obscurity within only the past 20 years. (cdc.gov)
  • 3 In addition, Flaviviridae such as Zika, Dengue and West Nile viruses, and Togaviridae such as Chikungunya also cause intraocular inflammation. (cehjournal.org)
  • x Baton Rouge, La.- The Louisiana Department of Health (DHH) is asking caregivers in Louisiana to take extra precautions to protect their loved ones from contracting West Nile virus. (la.gov)
  • This week's cases can be found in the weekly West Nile virus Surveillance report by clicking here . (la.gov)
  • News coverage has been dominated by concern for Eboa, but it is so important to remember that West Nile virus is a very present threat in Louisiana, especially for our loved ones who may have weak immune systems because of an existing medical condition or because of age," said LDH State Epidemiologist Dr. Raoult Ratard. (la.gov)
  • When people are infected with West Nile, the virus will affect them one of three ways. (la.gov)
  • Last year, Louisiana saw 34 cases of West Nile virus neuroinvasive disease in the state, which was down from 2002's high of 204 cases of West Nile virus neuroinvasive disease. (la.gov)
  • DHF), and West Nile virus (WNV) and chikungunya vi- camps. (who.int)
  • Prevalence of chronic comorbidities in dengue fever and West Nile virus: A systematic review and meta-analysis. (innspub.net)
  • Mosquito-transmitted arthropod-borne viruses (arboviruses) such as dengue virus, chikungunya virus, and West Nile virus constitute a major public health burden and are increasing in severity and frequency worldwide. (utmb.edu)
  • Type specific antibodies by neutralization test for Chikungunya virus, Mayaro, Zika and West Nile (consult for other antibodies). (ivami.com)
  • Caraballo H, King K. Emergency department management of mosquito-borne illness: malaria, dengue, and West Nile virus. (medscape.com)
  • Chikungunya fever is a self-remitting febrile viral illness that has been associated with frequent outbreaks in tropical countries of Africa and Southeast Asia. (medscape.com)
  • Other arboviruses cause sporadic cases of disease as well as occasional outbreaks. (medscape.com)
  • Below we review the methods used to investigate sylvatic cycles and available epidemiological data on sylvatic cycles of arboviruses in NHPs, primarily focusing on the most recent and largest arbovirus outbreaks in people (Fig. 1 ). (biomedcentral.com)
  • To assess if given vector density levels are protective against local arbovirus outbreaks, we first need to be able to keep mosquito densities at various but steady levels for long enough for arboviruses to show up in the various observational sites in nature. (berkeley.edu)
  • Author Manuscript questions or to monitoring vectors during outbreaks, such as the O'nyong-nyong virus(ONNV) outbreak in 1996 [19, 20]. (cdc.gov)
  • Darfur in Western Sudan has the most volatile camps of internally displaced persons (IDPs) and has expe- rienced several outbreaks of dengue, chikungunya and yellow fever. (who.int)
  • It was hypothesized that the aggressive vector control measures in Singapore has led to a very low mosquito population that could have selected for the circulation of a virus lineage with better fitness or population of vectors that are highly competent to transmit DENV. (monash.edu)
  • Dengue virus (DENV) is one of the most important and widespread arthropod-borne viruses, causing millions of infections over the years. (bvsalud.org)
  • 2018. Chikungunya virus: an emerging arbovirus in Pakistan. (innspub.net)
  • Epidemiological trend of chikungunya outbreak in Pakistan: 2016-2018. (innspub.net)
  • Musso D , Nhan T , Robin E , Roche C , Bierlaire D , Zisou K , Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014. (cdc.gov)
  • The largest-ever outbreak of the virus was in 1979-1980 and occurred in the western Pacific. (wikipedia.org)
  • Our level of concern with the Zika Virus outbreak is extremely high," Dr. Gregory R. Chiklis, President and CEO of ZeptoMetrix, relayed to his Executive Team. (prweb.com)
  • Nipah virus (NiV) was first isolated after an outbreak in Malaysia in 1999. (news-medical.net)
  • The first chikungunya outbreak in 2008 attests to these possibilities. (monash.edu)
  • town during an outbreak of DF and chikungunya. (who.int)
  • Vectors of chikungunya virus in Senegal: current data and transmission cycles. (ajtmh.org)
  • Because RRV is transmitted by mosquitos, it is considered an arbovirus, a non-taxonomic term for viruses borne by arthropod vectors. (wikipedia.org)
  • Preventing or limiting the transmission of dengue, chikungunya and Zika viruses is completely dependent on the control of mosquito vectors and reduction of person-mosquito contact. (who.int)
  • Ross River virus (RRV) is a small encapsulated single-strand RNA Alphavirus endemic to Australia, Papua New Guinea and other islands in the South Pacific. (wikipedia.org)
  • Review and update the detection guidelines and methodologies for laboratory surveillance of endemic, emerging, reemerging, and neuroinvasive Arboviruses. (paho.org)
  • Pathogenicity and transmission dynamics will be factors in determining where Zika virus will become endemic and what will be the most suitable methods of control. (cdc.gov)
  • Three zoonotic arboviruses endemic to Grenada include Zika virus, Chikungunya, and dengue (2). (researchsquare.com)
  • Chikungunya disease is suspected in patients who live in or have traveled to endemic areas if they develop sudden fever and arthralgias. (merckmanuals.com)
  • the report excludes chikungunya, dengue, yellow fever, and Zika virus disease cases, because these infections were acquired primarily through travel during 2021. (medscape.com)
  • Our ability to serologically diagnose infections with emerging arboviruses is often compromised by close antigenic relationships within virus families. (cdc.gov)
  • NETs are typically activated by bacterial infections, he added, as well as some viruses, including chikungunya, the arbovirus that causes the most tissue injury. (eurekalert.org)
  • The objective of this study was to estimate the number of homes in Grenada that have a bat infestation, and to determine whether there is a correlation between the number of bat infested homes with the type of roofing or the presence of arbovirus infections of human inhabitants. (researchsquare.com)
  • Results determined the percentage of individuals that had bat roosts in their households, whether this was of concern to them, whether they had taken any steps to keep bats out of their residence, and whether they had confirmed or suspected cases of dengue, Zika or Chikungunya virus infections. (researchsquare.com)
  • Recurrent recent arbovirus infections suggested by serologic data and unspecific symptoms highlight the need for exhaustive virologic testing. (tghn.org)
  • The animation illustrates large amounts of research data to show how the chikungunya virus infects our cells and uses its specialized machinery to release its genetic material into the cell and seed future infections. (nih.gov)
  • An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952-53. (ajtmh.org)
  • Tracking the re-emergence of epidemic chikungunya virus in Indonesia. (ajtmh.org)
  • Epidemic resurgence of Chikungunya virus in democratic Republic of the Congo: identification of a new central African strain. (ajtmh.org)
  • In 1956, an epidemic occurred in the Murray Valley which was compared to "acute viral polyarthritis" caused by Chikungunya virus. (wikipedia.org)
  • Further serological testing showed that patients who had suffered "epidemic polyarthritis" in Queensland had antibodies to the virus. (wikipedia.org)
  • This information is essential to better estimate the risks of chikungunya emergence, specifying the strong genetic proximity of the mosquito in South-East France with that of La Reunion Island, where the largest chikungunya epidemic ever occurred in France, and more generally in Europe. (pasteur.fr)
  • Since its arrival in the Western Hemisphere about 1 year ago, Zika virus, which had previously been associated with a clinically mild and inconsequential illness, is now increasingly suspected of being the cause of an alarming epidemic of neurologic birth defects and Guillain-Barré syndrome in tropical regions. (cdc.gov)
  • The oropouche virus has been moving closer to major cities in Brazil, and some public health officials think that the virus has major epidemic potential throughout the area in which it occurs. (msdmanuals.com)
  • The high-throughput screening method here presented can be proposed as a novel epidemiological surveillance tool to identify circulating arboviruses and to support preparedness to an epidemic in animals and humans. (tghn.org)
  • In 2015-2016 in the Recife Metropolitan Region, the authors of this study detected the tail end of a Zika epidemic, which was displaced by a chikungunya epidemic. (tghn.org)
  • We also present current putative data that Mayaro, o'nyong'nyong, Oropouche, Spondweni and Lumbo viruses exist in sylvatic cycles. (biomedcentral.com)
  • Informe de vigilancia de Arbovirus basada en laboratorio: Análisis de datos de virus Zika, dengue, chikungunya, mayaro y fiebre amarilla. (una.ac.cr)
  • Several murine models with Chikungunya virus-related joint and neurological diseases are being investigated. (medscape.com)
  • Since 2008, RELDA has supported the strengthening of laboratory networks and capabilities for timely detection of Dengue and other Arboviruses, strengthening surveillance and control programs for these diseases in the Americas Region. (paho.org)
  • Zika virus, the subject of several articles in the Emerging Infectious Diseases journal, reminds us of some of the impediments to responding to emerging vectorborne pathogens. (cdc.gov)
  • As an Honorary Consultant in Infectious Diseases, my research focuses on the epidemiology of influenza and other respiratory viruses in the UK and sub-Saharan Africa including COVID-19. (gla.ac.uk)
  • PAHO also requests that countries ensure that health professionals are trained in the diagnosis of dengue and other arboviruses, as well as in the adequate management of patients with these diseases. (sanpedrosun.com)
  • However, despite the introduction of these new arboviruses, dengue is the one that presents the highest number of diseases. (sanpedrosun.com)
  • Viruses transmitted by arthropods (arboviruses) are responsible for emerging and reemerging infectious diseases in different areas of the world, especially in tropical and subtropical regions. (fapesp.br)
  • Pakistan bears the poor living standards therefore, morbidity and mortality rates are much higher with respect to other countries due to these arboviruses diseases. (innspub.net)
  • Other state-of-the-art in vivo imaging techniques using bioluminescence imaging with luciferase-tagged pathogens and intravital 2-photon imaging systems are being evaluated for study of Chikungunya infection's chronic phase. (medscape.com)
  • First, Zika virus belongs to the most prevalent class of emerging pathogens, the zoonotic single- stranded RNA viruses, which have mutation rates as high as 1 base per 10 to the 4th power bases, each replication. (cdc.gov)
  • Recent studies documented that Grenadian bats can be infected with Zika, dengue and Chikungunya viruses and Leptospira bacteria among other pathogens. (researchsquare.com)
  • Introduction and establishment of exotic arboviruses in Singapore is highly plausible, especially with a population that is immunologically naïve to these pathogens. (monash.edu)
  • Like dengue virus, another flavivirus, Zika virus was likely originally a pathogen of subhuman primates. (cdc.gov)
  • Chikungunya is a virus of the Togaviridae family which has affected different parts of the world on several occasions: 2004 in the Indian Ocean, 2007 in Africa, 2007 in Europe, 2011 in the Pacific region, and 2013 in the Americas. (pasteur.fr)
  • It might seem as if Zika virus sprang from nowhere, but almost certainly it must have been infecting many more humans in Africa and Asia than we had been aware. (cdc.gov)
  • Here we review the investigation methods and available data on sylvatic cycles involving non-human primates and dengue, chikungunya, Zika and yellow fever viruses in Africa, dengue viruses in Asia and yellow fever virus in the Americas. (biomedcentral.com)
  • I was also involved in other projects regarding SARS-CoV-2 variants and disease severity in infants (DOI 10.3389/fmed.2022.896352), Rift Valley fever virus epidemiology in humans and animals in Kenya (DOI 10.1371/journal.pgph.0000505), and dengue virus evolution in Africa (ongoing Ph.D. candidate mentorship). (stanford.edu)
  • This research animation features the chikungunya virus , a sometimes debilitating, mosquito-borne pathogen transmitted mainly in developing countries in Africa, Asia and the Americas. (nih.gov)
  • After this first report, the virus circulated silently for more than 50 years in Africa and Asia, and few cases were described in isolation and without evidence of serious complications 2-5 . (bvsalud.org)
  • This observation supports the supposition that YF virus originated in West Africa. (medscape.com)
  • The virus is suspected to be enzootic in populations of various native Australian mammals, and has been found on occasion in horses. (wikipedia.org)
  • However there has been no systematic evaluation of the diversity of the entire bacterial populations within mosquito individuals particularly in relation to virus invasion. (datadryad.org)
  • Areas affected by dengue, chikungunya, and Zika viruses, worldwide, 2005, 2010, and 2015, illustrating the evolution of the geographic distribution of these viruses over the past decade ( 1 - 5 , 7 ). (cdc.gov)
  • aegypti specimens will be analyzed for the presence of dengue, chikungunya, and Zika viruses. (berkeley.edu)
  • In addition, this blocking ability is extended to chikungunya and zika viruses. (monash.edu)
  • Here, we found that ISG15 restricts Dengue and Zika viruses' replication through the stabilization of its binding partner USP18. (bvsalud.org)
  • Epidemiological Alert:Chikungunya increase in the Region of the Americas. (merckmanuals.com)
  • The new virus was named Ross River virus, and the disease Ross River fever. (wikipedia.org)
  • Other arboviruses from the ZeptoMetrix collection, such as Dengue Virus, Yellow Fever, and Chikungunya can be used to test that an assay is specific for the Zika Virus. (prweb.com)
  • Chikungunya disease usually presents with acute fever. (merckmanuals.com)
  • The first round only included dengue virus, while the latest round additionally included chikungunya, Zika and yellow fever viruses. (who.int)
  • Methodology/Principal findings We collected blood samples from patients suspected of having chikungunya fever (CHIKF) who presented to Clinical Hospital ISSSTE Dr. Roberto Nettel in Tapachula, Chiapas, Mexico. (uanl.mx)
  • [ 1 ] Arboviruses are maintained in transmission cycles between arthropods and vertebrate hosts, including humans and other animals. (medscape.com)
  • These studies provide evidence that local bat species are being infected with zoonotic viruses and indicate the possibility of Grenada's bat population viruses could spill over to humans. (researchsquare.com)
  • The oropouche virus is transmitted to humans by Culicoides paraensis , a species of biting midges (small flying insects) present in South and Central America and the Caribbean. (msdmanuals.com)
  • In humans, YF virus is transmitted to the mosquito from an ill human only during the initial 3-4 days of illness. (medscape.com)
  • Present the current situation and challenges faced in laboratory surveillance of the main Arboviruses in the region. (paho.org)
  • This study is a first step toward surveillance for arboviruses of public health and veterinary importance in Mpigi District. (cdc.gov)
  • LDH issues a weekly Arbovirus Surveillance Report that details cases detected thus far by parish. (la.gov)
  • Gallian P , de Lamballerie X , Salez N , Piorkowski G , Richard P , Paturel L , Prospective detection of chikungunya virus in blood donors, Caribbean 2014. (cdc.gov)
  • Proficiency for molecular detection of dengue virus remained high (83-94%) over the four-year period. (who.int)
  • Many arboviruses cause neuroinvasive disease such as aseptic meningitis, encephalitis, or acute flaccid paralysis (AFP). (cdc.gov)
  • As stated by Kuno & Chang [ 15 ], "The three commonly used data for identifying vertebrate reservoirs for arboviruses have been (i) virus isolation from suspected animals, (ii) relatively high antibody prevalence in the animals captured in the field and (iii) demonstration of viraemia (of higher virus titre and duration) in the suspected animals typically obtained under laboratory conditions" [ 15 ]. (biomedcentral.com)
  • 1 On becoming severely ill with signs of having contracted Ebola virus disease (EVD), the doctor was evacuated to an isolation facility in the United States for supportive care, where he eventually recovered. (cehjournal.org)
  • For clinical laboratory use, ZeptoMetrix has treated Zika Virus with its proprietary NATtrol™ inactivation process to manufacture non-infectious, molecular testing controls and an assay range validation panel. (prweb.com)
  • Developing high throughput methods for generating and analysing virus genomic sequences from clinical samples. (gla.ac.uk)
  • If a physician is not sure whether a patient is presenting with dengue, chikungunya or Zika, PAHO recommends that the clinical management and treatment of dengue begins immediately, without waiting for a laboratory diagnosis. (sanpedrosun.com)
  • Some viruses also can cause more characteristic clinical manifestations, such as severe polyarthralgia or arthritis due to Chikungunya virus or other alphaviruses (e.g. (cdc.gov)
  • The absence of microcephaly in infants exposed to the zika virus is not indicative of changes in ophthalmology, and it is essential that the ophthalmologist perform the investigations that are relevant to the clinical case. (bvsalud.org)
  • Buffalo, NY (PRWEB) February 03, 2016 -- ZeptoMetrix™ Corporation (ZMC), announced today the release of several new products to aid in the rapid development and ongoing quality control of molecular assays targeting the Zika Virus. (prweb.com)
  • The test performance of the 25 laboratories in the Region in 2016 was high with 23 (92%) reporting correct results in all specimens for dengue and chikungunya viruses. (who.int)
  • The observed proficiency for arbovirus diagnostics between 2013 and 2016 is an indicator of laboratory quality improvement in the Region. (who.int)
  • Dr. Espinal explained that the timely diagnosis of the disease has become more complex with the arrival of two new arboviruses: The Chikungunya virus in 2013 and the Zika virus in 2015, which present similar symptomatology. (sanpedrosun.com)
  • Chikungunya disease is an acute febrile illness followed by more chronic polyarthritis that can persist for months or years and be severe and disabling. (merckmanuals.com)
  • Most arboviruses are capable of causing an acute systemic febrile illness (e.g. (cdc.gov)
  • Using a murine model, Lum et al showed that anti-Chikungunya virus antibodies were elicited early in the course of the illness and were directed against the C-terminus of the viral E2 glycoprotein. (medscape.com)
  • Antibodies to Ross River virus have been found in a wide variety of placental and marsupial mammals, and also in a few bird species. (wikipedia.org)
  • Virus-specific IgM antibodies in CSF or serum. (cdc.gov)
  • Virus-specific IgM antibodies in CSF or serum but with no other testing. (cdc.gov)
  • In an immune response, viral neutralizing antibodies are present by the end of the first week, and the virus is rapidly cleared. (medscape.com)
  • A recent study discovered that 8% Grenadian bats are serologically positive to Chikungunya virus (5) and another showed 15% seroprevalence to rabies (6). (researchsquare.com)
  • Seroprevalence and antibody titers were low for both viruses. (tghn.org)
  • He noted that the causal relationship between the increase in incidence of microcephaly and neurological disorders and the circulating Zika virus was currently being investigated. (who.int)
  • Six unspecified California serogroup virus cases were also reported. (medscape.com)
  • This information is essential to better estimate the risks of chikungunya emergence in Europe. (pasteur.fr)
  • Since 2004, date of the well-known chikungunya emergence on La Reunion Island, the community of entomologists has focused a lot of efforts on the study of this species. (pasteur.fr)
  • They may act as refugia for arboviruses which enable re-emergence once human epidemics have passed and immunity in the population (herd immunity) has waned. (biomedcentral.com)
  • Because of these investigations, Uganda is currently a known hotspot for emergence of arboviruses of public health and veterinary importance [3, 4]. (cdc.gov)
  • To complement its current Tropical Disease microorganism offerings, ZeptoMetrix has added 3 strains of Zika Virus for the development and verification of molecular diagnostic assays. (prweb.com)
  • Further, they might provide selective environments where new strains of arboviruses can develop with increased (or decreased) virulence for people. (biomedcentral.com)
  • We used two strains of each virus, CHIK AND DEN: one strain was isolated from an imported case, and one from an autochthonous case. (pasteur.fr)
  • albopictus vector competence for chikungunya virus through an adaptive co-evolution process. (pasteur.fr)
  • albopictus in the transmission of both viruses. (pasteur.fr)
  • albopictus were also found to be highly susceptible to Zika and Ross River viruses. (monash.edu)
  • Mpox, previously known as monkeypox, is a zoonotic disease caused by the mpox virus. (news-medical.net)
  • Chikungunya virus-vector interactions. (cdc.gov)
  • Our work focusses on developing understanding of virus-host interactions by visualising them in a frozen-hydrated state at macromolecular resolution using cryo-electron tomography (cryo-ET). (gla.ac.uk)
  • Weaver SC , Lecuit M . Chikungunya virus and the global spread of a mosquito-borne disease. (cdc.gov)
  • OBJECTIVES: To estimate change in chronic hepatitis C virus (HCV) disease and the economic burden associated with comprehensive treatment of the chronic HCV-infected Medicaid population. (cdc.gov)
  • Questions are limited to clinicians who would like information related to Zika virus disease. (cdc.gov)
  • Ocular complications form part of post-Ebola virus disease syndrome, which also includes symptoms of joint and muscle pain and sometimes neurological problems. (cehjournal.org)
  • Prevention of chikungunya disease involves avoiding mosquito bites. (merckmanuals.com)
  • Zika virus disease is a mosquito-borne disease caused by Zika virus. (europa.eu)
  • Zika virus disease vocabulary is based upon the ONC Meaningful Use standards. (cdc.gov)
  • More than 130 arboviruses are known to cause human disease. (cdc.gov)
  • Urban transmission cycles of arboviruses in densely populated tropical regions can result in explosive epidemics and pandemics, although there can also be low levels of transmission only sufficient to maintain the viruses in the population. (biomedcentral.com)
  • For instance, Wolbachia modulates the replication of viruses or parasites. (datadryad.org)
  • Our results add a novel layer of complexity in the virus/host interaction interface and suggest that NS5 has a narrow window of opportunity to degrade STAT2, therefore suppressing host's IFN-I mediated response and promoting virus replication. (bvsalud.org)
  • Besides proteins, RNAs can interact with virus genomes to impact replication. (bvsalud.org)
  • Knockdown of several short non-coding RNAs, including miR19a-3p, and 7SK RNA results in a decrease in viral replication, suggesting that they act as virus-permissive factors. (bvsalud.org)
  • CONCLUSIONS: This study demonstrates that host RNAs can impact virus replication in permissive and restrictive ways, expanding our understanding of host factors and RNA-based gene regulation during viral pathogenesis. (bvsalud.org)
  • After the virus enters the bloodstream, hematogenous spread to the bone marrow, kidney (probable), liver (the main target), myocardium, and spleen ensues, and further replication occurs. (medscape.com)
  • Reverse genetic systems are a powerful tool for investigating virus-host interaction, for vaccine development, and for high-throughput screening of antiviral compounds. (bvsalud.org)
  • Here, we characterized SG immune response to dengue, Zika and chikungunya viruses using high-throughput transcriptomics. (pasteur.fr)
  • Of the 46 species identified, arboviruses had previously been isolated from 28 (60.9%) suggesting a high potential for arboviral transmission and/or maintenance in Mpigi District. (cdc.gov)
  • Other modes of transmission for some arboviruses include blood transfusion, organ transplantation, perinatal transmission, breast feeding, and laboratory exposures. (cdc.gov)
  • Arboviruses continue to pose serious public health threats in the World Health Organization (WHO) Western Pacific Region. (who.int)
  • YF virus, an arbovirus, is the type species for the family Flaviviridae and is a single, positive-stranded, enveloped RNA virus. (medscape.com)