• In the present report, we describe a rare case of primary signet ring cell carcinoma of the appendix with ovarian metastasesand unresectable peritoneal dissemination occurring in a 45-year-old female patient. (wjgnet.com)
  • The first recommendation would have been to biopsy 1 of these nodules at the time of surgery to rule out a disseminated peritoneal adenomucinosis or pseudomyxoma peritonei. (medscape.com)
  • Complete cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is the only curative treatment for pseudomyxoma peritonei (PMP) arising from the appendix. (biomedcentral.com)
  • 4. Pseudomyxoma peritonei: clinical pathological and biological prognostic factors in patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). (nih.gov)
  • 6. Hyperthermic intraperitoneal chemotherapy with oxaliplatin as treatment for peritoneal carcinomatosis arising from the appendix and pseudomyxoma peritonei: a survival analysis. (nih.gov)
  • 7. Patients with pseudomyxoma peritonei associated with disseminated peritoneal adenomucinosis have a significantly more favorable prognosis than patients with peritoneal mucinous carcinomatosis. (nih.gov)
  • 9. Validation of the Recent PSOGI Pathological Classification of Pseudomyxoma Peritonei in a Single-Center Series of 265 Patients Treated by Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy. (nih.gov)
  • 10. Management of pseudomyxoma peritonei by cytoreduction+HIPEC (hyperthermic intraperitoneal chemotherapy): results analysis of a twelve-year experience. (nih.gov)
  • 11. Recurrence and outcome after complete tumour removal and hyperthermic intraperitoneal chemotherapy in 512 patients with pseudomyxoma peritonei from perforated appendiceal mucinous tumours. (nih.gov)
  • 12. Early- and long-term outcome data of patients with pseudomyxoma peritonei from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. (nih.gov)
  • 14. Evaluation of complete cytoreductive surgery and two intraperitoneal chemotherapy techniques in Pseudomyxoma peritonei. (nih.gov)
  • 3. Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis. (nih.gov)
  • 15. The 7th Edition of the AJCC Staging Classification Correlates with Biologic Behavior of Mucinous Appendiceal Tumor with Peritoneal Metastases Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC). (nih.gov)
  • Treatment included staged therapeutic tumor debulking and right salpingo-oophorectomy followed by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). (bvsalud.org)
  • At the time of surgery to close a colostomy, a disseminated peritoneal carcinomatosis was noted with no evidence of disseminated disease to other organs. (medscape.com)
  • High peritoneal carcinomatosis index (PCI) is associated with an increased risk of surgical complications. (biomedcentral.com)
  • 8. Predictive and prognostic survival factors in peritoneal carcinomatosis from appendiceal cancer after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. (nih.gov)
  • Diffuse peritoneal adenomucinosis (DPAM) variant of PMP arising from a ruptured ovarian primary MCT after malignant transformation to a low-grade appendiceal-like mucinous neoplasm was ultimately confirmed. (bvsalud.org)
  • The introduction of complete cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) has dramatically improved outcomes for patients with PMP [ 5 ]. (biomedcentral.com)
  • I would recommend 6 cycles of oxaliplatin, leucovorin, and infusional 5-FU (FOLFOX) chemotherapy and periodic (eg, every 2-3 months) follow-up with CT scan and CEA levels until evidence of progressive disease. (medscape.com)
  • The peritoneal cancer index (PCI) [ 8 ] is a quantitative measure that describes the extent of peritoneal disease at surgery. (biomedcentral.com)
  • In addition, the fact that chemotherapy has demonstrated increased survival and quality of life in this disease would favor commencement of treatment at this time. (medscape.com)
  • Two of 4 lymph nodes were positive, there was serosal extension, and approximately 6 peritoneal implants were noted locally in the sigmoid peritoneum. (medscape.com)
  • Tumor nodules in the peritoneum were resected and the patient was treated with several cycles of irinotecan-based and capecitabine chemotherapy. (medscape.com)
  • However, during surgery to reanastomose his colostomy, several hundred small peritoneal implants were noted (95% were 2-3 mm in size), mostly in the upper abdominal quadrants. (medscape.com)
  • It is clear that the patient has developed progressive disease while on chemotherapy even though the CEA levels had normalized. (medscape.com)
  • Due to the more indolent nature of low-grade PMP compared to other peritoneal malignancies, our group has developed a two-step surgical approach for the curative treatment of patients with very high PCI in order to decrease the morbidity and mortality associated with the procedure and to offer a better alternative than debulking alone to patients with unresectable disease. (biomedcentral.com)