OsteosarcomaBone NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, AdjuvantOsteosarcoma, JuxtacorticalFemoral NeoplasmsAntineoplastic AgentsDoxorubicinCisplatinCombined Modality TherapyCell Line, TumorTreatment OutcomeNeoadjuvant TherapyMethotrexateLung NeoplasmsPrognosisCyclophosphamideDisease-Free SurvivalIfosfamideNeoplasm Recurrence, LocalSurvival RateSurvival AnalysisNeoplasm MetastasisLeg BonesEtoposideNeoplasm StagingTumor Cells, CulturedOsteoblastomaDrug Resistance, NeoplasmSarcoma, EwingBreast NeoplasmsHumerusGene Expression Regulation, NeoplasticDrug Administration ScheduleCarboplatinApoptosisOsteoblastsChondrosarcomaDog DiseasesAntimetabolites, AntineoplasticCell ProliferationFollow-Up StudiesPaclitaxelNeoplasmsTumor Markers, BiologicalTime FactorsAntibiotics, AntineoplasticMice, NudeSarcomaInduction ChemotherapyVinblastineBleomycinKaplan-Meier EstimateDeoxycytidineTaxoidsSalvage TherapyAmputationFatal OutcomeImmunohistochemistryAntineoplastic Agents, AlkylatingAntineoplastic Agents, PhytogenicExtremities