- Smooth muscle cells in human atherosclerotic plaques express the fractalkine receptor CX3CR1 and undergo chemotaxis to the CX3C chemokine fractalkine (CX3CL1). (prosci-inc.com)
- The term chemokine refers to a specific class of cytokines that mediates chemoattraction ( chemotaxis ) between cells. (wikidoc.org)
- The receptor on the monocyte or other phagocyte for the CX3CL1 signal has been shown to be CX3CR1 in vivo. (wikipedia.org)
- Ligands of CX3CR1 (Cx3cl1) and CCR2 (Ccl2, Ccl7, Ccl12) were significantly overexpressed in the left ventricle at the early stages after mechanical pressure overload. (bvsalud.org)
- These findings strongly suggest the involvement of the CX3CR1/CX3CL1 pathway in the pathogenesis of left-ventricular hypertrophy. (bvsalud.org)
- Cytokine cocktail -induced expression by a factor of >30 was observed for CCL5, CCL8, CCL22, CX3CL1, CXCL9, and CXCL10 (asterisks indicate significant differences between control and cytokine-treated islets). (reprokine.com)
- and the proteins (or peptides): fractalkine (CX3CL1), interleukin-8 (IL-8), complement components C3a and C5a, split tyrosyl tRNA synthetase (mini TyrRS), dimerized ribosomal protein S19 (RP S19), endothelial monocyte-activating polypeptide II (EMAP II) and formyl peptides (including N-formylmethionine-leucyl-phenylalanine, fMLP). (wikipedia.org)
- Four types of find-me signals released from apoptotic cells have been discovered: Lipid lysophosphatidylcholine (LPC) Sphingosine 1-phosphate (S1P) Fractalkine CX3CL1 Nucleotides ATP and UTP All of these molecules are linked to monocyte or macrophage recruitment towards dying cells. (wikipedia.org)
- However, chemotaxis of both CCR5-transfected cells and primary macrophages was inhibited by more than 90% by plasma from Ad35K-infected animals compared with control plasma from animals injected with AdGFP. (ox.ac.uk)
- juega un papel crítico en la PLASTICIDAD SINÁPTICA mediada por el receptor NMDA. (bvsalud.org)
- In vitro , PDGF-BB, PDGF dimer, promotes chemotaxis in white blood cells as well as proliferation of vascular smooth muscle cells, fibroblasts and capillary endothelial cells. (fujifilm.com)
- The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 5.0-10 ng/ml. (watson-bio.com)
- Recombinant Human CX3CL1 which is a single non-glycosylated polypeptide chains contains 76 amino acids and it shares approximately 78 % and 83 % amino acid sequence homology with the murine and rat protein. (watson-bio.com)