Chemicals and drugs. Medical search. Frequent questions

Discussions of common classes of drugs and other poisonous substances can be found at Medscape Reference, as listed in the Further Reading section. (medscape.com)
Mandatory qualification for the recruitment of chemical analysts in Punjab's chemical laboratories is not commensurate with the advancements in science and coming up of new subjects for analysing, specifically, cases under the Narcotic Drugs and Psychotropic Substances (NDPS) Act. (hindustantimes.com)
Dangerous PFAS (per-and-poly-fluoroalkyl substances), also known as "forever chemicals," are in many food packages manufactured by large corporations who are more concerned about prolonging the "shelf life" of the food, all while compromising and shortening the life expectancy of the consumers of those food products. (newstarget.com)
Different resources use different naming conventions for chemical substances. (tufts.edu)
The Chemical Abstracts Service (CAS) of the American Chemical Society assigns unique identification numbers to chemical substances, e.g. 1007-32-5. (tufts.edu)
The Food, Drugs and Chemical Substances (Food Labelling, Additives and Standards) (Amendment) Regulations, 2012. (who.int)
Per- and polyfluoroalkyl substances (PFAS) are a large, complex group of synthetic chemicals that have been used in industry and consumer products worldwide since the 1940s. (cdc.gov)
These substances have been dubbed "forever chemicals" because they do not degrade and are ubiquitous in the environment. (medscape.com)
Ototoxicity occurs when chemical substances affect the auditory or hearing system. (cdc.gov)

Because endogenous chemicals bind and activate FXR, it is important to examine which xenobiotic compounds would disrupt normal receptor function. (nature.com)
These results provide important information to prioritize chemicals for further investigation and suggest possible modes of action of compounds in FXR signaling. (nature.com)
GC/MS analysis allows separation of compounds based on their retention time within a chromatography column and identification of each compound by the characteristic fragments into which a given chemical is broken following ionization of the compound. (medscape.com)
For more than a century, most catalysts were prepared using chemical compounds called phosphines," said Guy Bertrand, the lead author of the study and Distinguished Professor of chemistry. (innovations-report.com)
This review covers the basic chemistry of these novel psychoactive compounds and relates them to endogenous neurotransmitters and existing drugs of abuse. (erowid.org)
Trivial and systematic chemical compound names, for example methoxetamine, 4-methoxyphencycline, 4-fluorotropacocaine and ethyl phenidate were entered into PubMed to retrieve data on these compounds. (erowid.org)
Collection of interactive tables that provide physical, thermal and electrical properties of chemicals compounds and solvents. (tufts.edu)
Target-focused compound libraries have been a key enabling component of the tool kit opening up kinase drug discovery, consisting of collections of compounds designed to interact with a family of related kinase targets (4). (ddw-online.com)
Such libraries are used for screening against therapeutic targets in order to find hit compounds that may be further developed into drugs and/or used as research tools to better understand the underlying biology and its relevance to pharmacological intervention. (ddw-online.com)
However, computational methods for the selection of molecules for drug discovery are constantly evolving and new approaches are now available that can assist the medicinal chemist in selecting new compounds for library synthesis. (ddw-online.com)
One of the most critical steps in this process is the first one-identifying new chemical compounds that could be developed into new medicines. (phys.org)
To make things even more complicated, because PAINS react with targets much more strongly than most compounds that are true drug candidates, PAINS often appear as the most promising hits in screening. (phys.org)
An estimated 5% to 12% of compounds in the screening libraries academic institutions use for drug discovery consist of PAINS. (phys.org)
Scientists misled by a false positive can waste considerable time if they try to develop these compounds into usable drugs. (phys.org)
Taking steps to ensure that these types of compounds don't make it to the next stage of drug discovery can avoid wasted time and effort and ultimately lead to a more efficient and cost-effective drug discovery process. (phys.org)
The goal of this initiative is to support research aimed at (1) identification of targets and pathways by which transcriptional activity of HIV can be suppressed in HIV reservoirs including the CNS in people with SUD, and (2) application of emerging small molecule drug discovery approaches to identify novel compounds that can be utilized as pharmacological probes and as drugs to suppress HIV transcription in people with HIV-SUD comorbidity. (cdc.gov)

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However, over the same period protein kinases have rapidly become one of the most significant classes of drug targets for the pharmaceutical industry, with the global market for kinase therapies being about US$15 billion per annum in 2010 and this value is predicted to double by 2020 (3). (ddw-online.com)

We used a cell-based human FXR β-lactamase ( Bla ) reporter gene assay to profile the Tox21 10K compound collection of environmental chemicals and drugs. (nature.com)
However, the effects and the mechanisms by which environmental chemicals interact with FXR to affect BA homeostasis are only emerging. (aspetjournals.org)
The National Report on Human Exposure to Environmental Chemicals (Report ) present biomonitoring data on the exposure of the U.S. population to environmental chemicals. (cdc.gov)
Advances in analytical methods allow us to measure lower and lower levels of environmental chemicals in people. (cdc.gov)
For more information about environmental chemicals, web links are provided below. (cdc.gov)
Synergistic activation of estrogen receptor with combinations of environmental chemicals. (cdc.gov)

Workers and employers should review chemical safety data sheets (SDSs) to identify the various ototoxic chemicals currently used in the workplace. (cdc.gov)
Consider the risks associated with ototoxic chemicals and determine if they are vital to the job site and the desired outcomes of the project. (cdc.gov)
Recent guidelines and legislative developments and alternative strategies for preventing auditory effects of exposure to ototoxic chemicals are examined. (cdc.gov)

Consequently, small-molecule drug discovery usually involves an iterative process of molecular design, chemical synthesis, biological assay and data analysis feeding directly into the next cycle, but this process always needs a chemical starting point. (ddw-online.com)

Launched in 1981, Speciality Chemicals Magazine has been the leading publication dedicated to the fine and speciality chemicals industry for over 40 years. (specchemonline.com)

The scientific programme will include over 25 plenary lectures by internationally well-known scientists, covering the main stages of modern drug discovery. (rsc.org)
The discovery of new drugs is a tedious process with many complicated steps, says lead investigator Milan Mrksich. (sciencenews.org)
Despite the growing interest in FXR ligands in drug discovery, little is known with regard to the roles of FXR in mediating or protecting xenobiotic-induced toxicity. (nature.com)
Stay connected with all of the latest from Drug Discovery News. (drugdiscoverynews.com)
Is novel chemistry the final frontier for ubiquitin system drug discovery? (ddw-online.com)
Although the widespread use of target-focused libraries has led to the rapid expansion of novel chemistry as research tools in drug discovery to exploit many classes of drug target, the ubiquitin system still remains a largely untapped medicinal chemistry opportunity. (ddw-online.com)
In this article, we propose that chemical libraries which target the ubiquitin system are the missing keys to unlock the therapeutic potential of ubiquitin system drug discovery. (ddw-online.com)
As James Black is quoted as saying: "The most fruitful basis for the discovery of a new drug is to start with an old drug (1). (ddw-online.com)
Research on protein kinases is now reported to account for approximately 30% of the drug discovery programmes in the pharmaceutical industry and more than 50% of cancer research and development (3). (ddw-online.com)
Drug discovery is an expensive process and only ~ 10% of all drugs in Phase 1 clinical trial gain regulatory approval by the US Food and Drug Administration (FDA), with oncology drugs having the lowest likelihood of success. (stanford.edu)
Modern drug discovery is an expensive and complicated process . (phys.org)
I am a medicinal chemist who has been working in the drug discovery field for over 26 years, and one of the greatest challenges I have faced in my research is selecting good candidates from drug screening tests. (phys.org)
Biological Activities, Chemical Profiles and In Silico Drug Discovery. (bvsalud.org)

The FDA's recent actions on chemical abortion drugs have harmed the health of countless women and girls and undermined the rule of law by illegally removing every meaningful safeguard from the chemical abortion drug regimen. (adfmedia.org)
Earlier this month, Family Research Council, along with the same thirteen other pro-life organizations, also sent letters addressed to the leadership of cvs health and walgreens boots alliance pharmacy chains asking them to stop dispensing the chemical abortion drug regimen. (menafn.com)

Gibbons S. "'Legal Highs' - novel and emerging psychoactive drugs: a chemical overview for the toxicologist" Clin Toxicol (Phila) . (erowid.org)
Although the socio-educational center doesn't work with this question, our proposal aims to consider this specific demand that related criminality and psychoactive drugs. (bvsalud.org)

Whereas historically drugs such as heroin and cocaine have been considered the "dangerous" drugs, in the past decade or longer, prescription drug abuse has far surpassed "illegal" drugs as agents of lethal drug toxicity. (medscape.com)
The majority (39%) of those that failed to get approval were due to a poor understanding of pharmacokinetics which has an impact on a drug compound's efficacy, safety and toxicity due to under- and over-dosing of drugs. (stanford.edu)
Whereas historically drugs such as heroin and cocaine have been considered the "dangerous" drugs, in recent years, prescription drug abuse has far surpassed "illegal" drugs as agents of lethal drug toxicity. (medscape.com)

Pervasive 'Forever Chemicals' Linked to Thyroid Cancer? (medscape.com)
New evidence points to an association between exposure to "forever chemicals" and an increased risk for thyroid cancer . (medscape.com)
Dangerous 'Forever Chemicals' in Your Everyday Items Are Causing Cancer ," Newsweek reported. (medscape.com)

Hemolytic anemia caused by chemicals and toxins is a lack of red blood cells that occurs when red blood cells are excessively damaged by certain chemicals or toxins. (medlineplus.gov)
The onset, site, mechanism and extent of ototoxic damage caused by these toxins vary according to risk factors that include type of chemical, interactions, exposure level and duration of exposure as is the case with therapeutic drugs. (cdc.gov)

Drug and Chemical Toxicology is a bimonthly peer-reviewed medical journal that publishes full-length research papers, review articles, and short communications that encompass a broad spectrum of toxicological data surrounding risk assessment and harmful exposure. (wikipedia.org)
Environmental chemical exposure could affect liver disease development. (aspetjournals.org)
SIGNIFICANCE STATEMENT Environmental chemical exposure significantly contributes to the development of cholestasis and nonalcoholic steatohepatitis (NASH). (aspetjournals.org)
Exposure to endocrine-disrupting chemicals, including PFAS, has been identified as a potential risk factor for thyroid cancer, with some research linking PFAS exposure to thyroid dysfunction and carcinogenesis . (medscape.com)
Hazardous chemicals are not only dangerous to our health from inhalation, ingestion, and skin contact, but they can also cause hearing loss when combined with sound levels that are lower than the NIOSH recommended 85 decibel time weighted average exposure limit for noise. (cdc.gov)
To prevent hearing loss, chemicals that have ototoxic characteristics should be identified prior to exposure. (cdc.gov)
[vii] If ototoxicant chemicals are present, the ACGIH suggests noise exposure reduction using engineering, administrative, and PPE controls. (cdc.gov)

This Chemical Abstracts Service (CAS) database offers property data on organic and inorganic molecules, proteins and polymers as well as experimental procedures, conditions, yields and solvents for chemical reactions. (tufts.edu)

This will increase its chemical synthesis capacity for intermediates and APIs by 45%, particularly for products in high demand where Olon is already the market leader. (specchemonline.com)
bulk drugs, dyes, intermediates etc. (indiacatalog.com)
Be the first person to write a business review for Aarti Group of Industries, Mumbai - bulk drugs, dyes, intermediates etc. (indiacatalog.com)

Mumbai based Aarti group, comprising of Aarti Industries Ltd., Alchemie International, Valiant Chemicals Corporation and Aarti Drugs Limited, caters to leading manufacturers of dyes, pigments, pharmaceuticals, rubber and agrochemicals worldwide. (indiacatalog.com)
Provides technical services in setting up and maintenance of petrochemical, chemical, pharmaceuticals, agrochemicals and polymer processing plants, hazardous / non-hazardous bulk liquid handling terminals. (indiacatalog.com)
His work cuts across disciplines to deliver advances in pharmaceuticals, chemical engineering and medical devices. (rdworldonline.com)

Kitchen counter with paraphernalia used in intravenous drug use. (medscape.com)
Miller is charged with chemical endangerment of a child, possession of a controlled substance, obstruction of justice by using a false identity, possession of drug paraphernalia, second-degree possession of marijuana and third-degree promoting prison contraband. (whnt.com)
Marshall is charged with chemical endangerment of a child, possession of a controlled substance, possession of drug paraphernalia and second-degree possession of marijuana. (whnt.com)

Several medical examiners' offices that routinely test for alcohol and drugs of abuse report finding some substance on toxicologic analysis in at least 50% of their cases. (medscape.com)
The company will henceforth prioritise its drug substance and analytical testing businesses, which are based across 13 sites worldwide, including the recently acquired Snapdragon Chemistry and Q1 Scientific. (specchemonline.com)
Thus, searching by substance name is the least efficient way to find chemical information. (tufts.edu)
The specific absorption frequencies of a chemical substance are shown in Fig. 1 [1]. (ntt-review.jp)

Bioassays involve placing a chemical compound together with the target of interest and measuring the strength of their interaction. (phys.org)

CDMO Hovione has acquired its Portuguese compatriot ExtremoChem, a chemical synthesis start-up focused on bio-inspired synthetic sugars. (specchemonline.com)

ARMACO is an international process engineering firm providing specialized engineering services to industries related to Phosphates, Oleochemicals, Soaps & Detergents and Specialty chemicals. (indiacatalog.com)
Chem Consultants provides turnkey projects for Agrochemical, Pharmaceutical and Specialty Chemical Industries.Our objective is to commence the production as per optimum yield and capacity today possible by technology. (indiacatalog.com)

Laboratory Networks (ICLN) requires these laboratories maintain testing capabilities for exposures to the following high threat chemical agents: mustard agents, nerve agents, and toxic industrial chemicals. (cdc.gov)
Advanced Research and terrorism agents such as cyanide, toxic metals, and toxic industrial chemicals. (cdc.gov)

Entire textbooks have been written on forensic toxicology and individual drugs and chemicals that can cause death. (medscape.com)
Legal highs' from the phenylethylamine, cocaine, tryptamine and phencyclidine classes are increasingly being marketed and, in the majority of cases, little is cited in the literature on their true chemical identity, pharmacology or toxicology. (erowid.org)

PFAS are a class of widely used synthetic chemicals found in many consumer and industrial products, including nonstick cookware, stain-repellent carpets, waterproof rain gear, microwave popcorn bags, and firefighting foam. (medscape.com)

Ann Thayer, C&EN senior correspondent, explains that in 1905, the nonprofit standards-setting U.S. Pharmacopeial Convention (USP) first introduced a method for checking medicines for arsenic, mercury and other heavy metals, which can be harmful to health. (acs.org)

Chemists at the University of California, Riverside have synthesized a new class of carbenes - molecules that have unusual carbon atoms - that is expected to have wide applications in the pharmaceutical industry, ultimately resulting in a reduction in the price of drugs. (innovations-report.com)
Called cyclic alkyl amino carbenes or CAACs, the molecules attach themselves to metals, such as palladium, to form highly efficient catalysts that allow chemical transformations otherwise considered impossible. (innovations-report.com)
Molecular clusters may contain pharmaceutical drug molecules and hydrogen molecules, amongst others. (ntt-review.jp)
Terahertz spectroscopy is a useful tool that can identify hydrogen bonds present in molecules that comprise various bio-specimens, including organic acids, amino acids, sugars, drugs, polypeptides, DNA, and proteins as well as macrostructures such as cancer cells. (ntt-review.jp)
Since most amino acids and pharmaceutical drug molecules contain hydrogen bonds, quantitative analysis from terahertz spectrum peaks is possible. (ntt-review.jp)
In contrast to X-ray imaging, terahertz chemical imaging (TCI) can identify molecules by their molecular network spectrum. (ntt-review.jp)
Bioavailability, rather than describing physiochemical properties of pharmaceutical drug molecules, describes the way in which chemicals are absorbed in the human body and is important in determining the effective dosages of particular medications. (ntt-review.jp)

Pharmaceutical and biotech firms, which spend billions of dollars every year searching for new drugs, keep an eye open for technologies to make their drug screening more fruitful. (sciencenews.org)
James Bruno, president of the consulting firm Chemical and Pharmaceutical Solutions, notes that travel restrictions are already interrupting business with Chinese suppliers. (acs.org)
All of this can dramatically reduce the cost of manufacturing drugs, given that pharmaceutical companies are increasingly using carbene-supported catalysts for their chemical reactions. (innovations-report.com)
P rotein kinases, on the other hand, have become one of the most important classes of drug targets for the pharmaceutical industry over the last decade, following on from the exploitation of kinase-focused libraries for at least the last two decades. (ddw-online.com)
Prices Current of Drugs and Druggists' Articles, Chemical and Pharmaceutical Preparations, Proprietary Medicines & Perfu. (pbagalleries.com)
I have a question regarding full chemical testing for drug excipient in pharmaceutical industry. (acs.org)
In this article, we explain terahertz time-domain spectroscopy, the principles of terahertz chemical imaging, and a multicomponent quantitative analysis method for amino acids that can visualize pharmaceutical crystalline polymorphs as an example of this technology. (ntt-review.jp)

The definitive documentary on psychotropic drugging this is the story of the high-income partnership between drug companies and psychiatry which has created an $80 billion profit from the peddling of psychotropic drugs to an unsuspecting public. (godlikeproductions.com)

GABA and glutamate are both neurotransmitters - chemical messengers that help nerve cells in the brain communicate. (scienceblog.com)

US Food and Drug Administration, August 2019. (acs.org)
A Texas judge heard arguments from both sides Wednesday in a case questioning the legality of the Food and Drug Administration's (FDA) 2000 approval of the chemical abortion drug mifepristone. (catholicvote.org)
The Food and Drug Administration has given its full approval to Leqembi, the first drug shown to slow down Alzheimer's disease. (wutc.org)
The following quote may be attributed to Alliance Defending Freedom Senior Counsel Erin Hawley , vice president of the Center for Life and regulatory practice, regarding a conditional cross-petition ADF attorneys filed with the U.S. Supreme Court Thursday in Alliance for Hippocratic Medicine v. U.S. Food and Drug Administration . (adfmedia.org)
Concerns over potential health risks of BPA have led to restrictions on the use of BPA in certain baby and children products (U.S. Food and Drug Administration 2014). (cdc.gov)
In comparison, only recently has the ototoxicity of chemicals found in the environment from contaminants in air, food or water, and in the workplace become a concern for audiologists and other health professionals. (cdc.gov)

We anticipate that expanding our TMFS method to the more than 27,000 clinically active agents available worldwide across all targets will be most useful in the repositioning of existing drugs for new therapeutic targets," they said. (acs.org)
L ike protein phosphorylation by kinases, protein ubiquitylation regulates many aspects of cell function and provides a wealth of drug target opportunities across many therapeutic areas including cancer, cardiovascular, metabolism, inflammation, neurodegeneration and infectious diseases. (ddw-online.com)
The ototoxicity of therapeutic drugs has been a concern in the field of audiology for many years. (cdc.gov)

LRN-C laboratories assist CDC in testing samples for chemical sures to toxic chemical agents exposures and serve as front line communication among the CDC such as cyanide, nerve agents, and local health officials, hospitals, and poison control centers. (cdc.gov)
Early detection and accurate identification of chemical threat agents are critical for effec- tive treatment and minimizing additional exposures. (cdc.gov)
and 4) Evaluation of Chemical Exposures at a Vape Shop. (cdc.gov)

He argued that the FDA has been putting pregnant mothers in increasingly dangerous situations since 2000 as safeguard after safeguard surrounding chemical abortion has been eradicated. (catholicvote.org)
The FDA's unprecedented actions did not reflect scientific judgment but rather revealed politically driven decisions to push a dangerous drug regimen without regard to women's health. (adfmedia.org)
Chemical abortion drugs are extremely dangerous--they take the life of an unborn child, and they can put the life of that child's mother in jeopardy. (menafn.com)

The technique for repurposing existing medicines could cut drug development costs and make new medicine available to patients faster, they report in ACS' Journal of Medicinal Chemistry . (acs.org)
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. (drugs.com)

They describe using TMFS to discover evidence that Celebrex, the popular prescription medicine for pain and inflammation, has a chemical signature and architecture suggesting that it may work against a difficult-to-treat form of cancer. (acs.org)
Feodoroff M, Mikkonen P, Turunen L, Hassinen A, Paasonen L, Paavolainen L, Potdar S, Murumägi A, Kallioniemi O, Pietiäinen V. Comparison of two supporting matrices for patient-derived cancer cells in 3D drug sensitivity and resistance testing assay (3D-DSRT). (helsinki.fi)
Feodoroff M, Mikkonen P, Arjama M, Murumägi A, Kallioniemi O, Potdar S, Turunen L, Pietiäinen V. Protocol for 3D Drug Sensitivity and Resistance Testing of Patient-Derived Cancer Cells in 384-Well Plates. (helsinki.fi)

The former has complex vascular permeability, heterogeneous interstitial fluid pressure and disorganized lymphatic drainage which collectively impair diffusion of drugs into tumour tissues and even drug distribution in the same tumor tissue. (stanford.edu)
However, it is difficult to extrapolate overall drug penetration in the heterogeneous tumor tissue environment from a single sampling site, and this in turn leads to inaccurate PK assessment,' says Seo. (stanford.edu)

these include both intoxication from abuse of illicit drugs and deaths resulting from a consequence of medication taken as medical therapy. (medscape.com)
The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. (drugs.com)
Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. (drugs.com)
Recognizing that a drug or medication is causing gastroenteritis can be difficult. (msdmanuals.com)
In mild cases, a doctor can have a person stop taking the drug or medication and later start taking it again. (msdmanuals.com)
If the symptoms subside when the person stops taking the drug or medication and resume when the person starts taking it again, it may be the cause of the gastrointestinal symptoms. (msdmanuals.com)
In severe cases of gastroenteritis, a doctor may instruct the person to stop taking the drug or medication permanently. (msdmanuals.com)

Database of references to chemical journals, books, conference proceedings and patents. (tufts.edu)

Now that you know a little about how to search for chemical information, you need to know where search. (tufts.edu)

Have you been listening to those drug dealers (MDs) and disease spreaders (Centers for Disease Continuation - CDC) again? (newstarget.com)

C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society. (acs.org)
We start this off with nicotine, the world's third-most addictive drug, used by every sixth person in the world, daily. (newstarget.com)

The small-molecule drug voriconazole (VRC) shows a complex and not yet fully understood metabolism. (mdpi.com)

The carbene-based catalysts we report can simplify complex chemical preparations. (innovations-report.com)

SciFinder also provides references to the chemical, biochemical and chemical engineering literature from the CAplus and MEDLINE databases. (tufts.edu)

Sivanesan Dakshanamurthy and colleagues explain that drug companies must limit efforts to market new drugs because the current approach is so expensive, time-consuming and prone to failure. (acs.org)
Using an inorganic salt as the glue sticking together two different APIs in a "drug-bridge-drug" approach, we successfully created and characterized three different ternary ionic cocrystals (TICCs). (rsc.org)

Some chemical and herbal drugs are used to prevention and treatment of these lesions. (vin.com)

As noted earlier, drugs are found in 50% of forensic autopsies (when tested) and that drugs or medications are responsible for causing or contributing to death in over 20% of deaths unrelated to natural causes in the United States. (medscape.com)
Same goes for blood thinners (rat poison), deadly statin drugs , and other cholesterol medications that feature side effects that are worse than the condition being treated. (newstarget.com)
Pharmacies across the country should recognize that distributing these drugs is antithetical to their mission of providing medications that allow life to flourish,' Szoch concluded. (menafn.com)
Although it is usually caused by infection with a microorganism, it can also be caused by ingesting drugs, medications, or chemicals. (msdmanuals.com)
Nausea, vomiting, and diarrhea are common side effects of many drugs and medications. (msdmanuals.com)

We've developed a method for chemical processing that combines all the benefits of flow chemistry with a much simpler way of using metal catalysts in them, reducing the number of steps that need to be taken. (www.csiro.au)
I want to get the latest chemistry news from C&EN in my inbox every week. (acs.org)
Rather than just recruiting the persons as chemical analysts with basic qualification of MSc chemistry, justice Singh said the court was of the opinion that other qualifications, such as MSc in pharmacy, pharmacology, biotechnology or other advanced sciences which are presently developing, could be added as qualification so that persons equipped with required knowledge are available and a proper analysis could be carried out. (hindustantimes.com)

Before now, making catalytic chemical reactions faster and more scalable has been a challenge, but this smarter process, that gives a better result in a short period, lends itself to more efficient scale up," Dr Gardiner said. (www.csiro.au)
In their paper, the UCR chemists discuss a set of chemical reactions involving the use of catalysts other than those that are CAAC-based. (innovations-report.com)
Allergic reactions to drugs and chemicals are mediated by an adaptive immune response involving specific T cells. (frontiersin.org)
Adverse drug reactions (ADRs) are a major public health problem. (frontiersin.org)
On one hand, drug-specific T cells provide the necessary help for mounting an effective B-cell response observed in immediate-type hypersensitivity reactions. (frontiersin.org)
In the course of your research, you may need information about chemical properties, structures and reactions, and articles from the chemical, biochemical and drug literature. (tufts.edu)

In addition, organization's procurement departments and related personnel should be trained to identify chemicals that are potential ototoxicants so that the hazard can be identified before the hazardous product is purchased. (cdc.gov)

Most studies have focused on the identification of memory T cells that recognize drugs/chemicals and the insights obtained have led to the development of allergy diagnostic tests ( 7 - 21 ). (frontiersin.org)
After three lots of full chemical testings are met, is identification analysis being performed only upon receipt? (acs.org)
Terahertz spectroscopy allows the detection and identification of various molecular networks of chemical bond interactions, including those of hydrogen bonds. (ntt-review.jp)
Because the technique can reveal the molecular network rather than only the molecular distribution, we believe that TCI can provide a new method for both drug identification and pathological examination. (ntt-review.jp)

Researchers rely heavily on bioassays to identify potential drug candidates. (phys.org)
In conclusion, cratoxanthone E and morellic acid are promising anti-COVID-19 drug candidates that warrant further detailed in vivo experimental estimation and clinical assessment. (bvsalud.org)

This observation has come from the Punjab and Haryana high court in an ongoing case raising questions over the authenticity of chemical analysts' reports, especially of the Kharar chemical laboratory, that play a crucial role in deciding a large number of NDPS cases pending before several courts. (hindustantimes.com)
As of now, there are only two agencies in Punjab for analysing chemical or NDPS samples of thousands of cases pending in courts across the state and these agencies are reeling under pressure due to shortage of manpower. (hindustantimes.com)

Typically, pharmacokinetics data are derived from blood measurements of circulating drug concentrations, but such method does not capture drug absorption within tumors. (stanford.edu)
Specific chemical absorption frequencies. (ntt-review.jp)

American Chemical Society ) Robert S. Langer, Sc.D., the David H. Koch Institute Professor at Massachusetts Institute of Technology, has been named winner of the 2012 Priestley Medal by the American Chemical Society (ACS). (rdworldonline.com)

On the other hand, a large T-cell repertoire found in multiple donors would underline the potential of a drug/chemical to be recognized by many donors. (frontiersin.org)
Understanding this role has the potential to reveal efficient strategies not only for allergy diagnosis but also for prediction of the immunogenic potential of new chemicals. (frontiersin.org)
Enhance brand visibility and showcase your business potential with the help of our Chemical-Drug Dependency Counselors Email list. (hyenafox.com)
Below is the toxicological section of a sample SDS that shows where a chemical is identified as a potential neurotoxicant (ototoxicants are often called neurotoxicants). (cdc.gov)

Ron Brusven is a licensed Alcohol and Drug Counselor with over thirty years of recovery and work in. (brainerd.com)
Meridian Behavioral Health Outpatient alcohol and drug treatment serving Crow Wing County and surrou. (brainerd.com)

The consequences of drug and chemical allergy can be severe, including systemic adverse effects ( 1 - 3 ). (frontiersin.org)

For two decades or more, the rate at which drugs against new targets are launched has been relatively constant but the rate of developing drugs against completely new classes of drug target has been significantly lower (2). (ddw-online.com)
These methods may also incorporate simple calculated properties, for example the so-called 'Rule of 5' (5) to ensure libraries stay within sufficiently druglike areas of chemical space as well as existing structure activity relationship data describing the interaction of the chemical matter with the principle biological target, as well as related targets. (ddw-online.com)

These observations may also suggest that in the case of drug/chemical allergy, the T-cell repertoire results from particular properties of certain TCR to recognize hapten-modified peptides without need for previous thymic selection. (frontiersin.org)

Anatomy8

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Chemicals and Drugs104

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Psychiatry and Psychology2

Phenomena and Processes54

Disciplines and Occupations11

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Substances9

Compounds16

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20201

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Ototoxic chemicals3

Small-molecule drug discovery1

Speciality chemicals1

Discovery13

Abortion drug regimen2

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Toxicity3

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Toxins2

Exposure7

Solvents1

Intermediates3

Pharmaceuticals3

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Substance4

Compound1

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Specialty2

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PFAS1

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Molecules7

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Candidates2

Punjab2

Absorption2

American Chemica1

Potential4

Alcohol2

Systemic1

Targets2

Recognize1