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  • moiety
  • One is a chelating moiety that interacts with the zinc ion and the other is a hydrophobic extension from the catalytic site that project into S1' pocket (P1' group) of the metalloproteinase. (wikipedia.org)
  • EDTA
  • EDTA, or ethylenediaminetetraacetate, ( - O 2 CH 2 ) 2 NCH 2 CH 2 N(CH 2 CO 2 - ) 2 , is a common hexadentate chelating agent. (encyclopedia.com)
  • In vitro, EDTA, 1,10-phenanthroline and other chelating compounds lower the concentration of metal to the point where the metal is removed from the enzyme active site. (wikipedia.org)
  • A most prominent derivative of ethylenediamine is the chelating agent EDTA, which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde. (wikipedia.org)
  • chelation
  • Macrocyclics, Inc., a manufacturer of customized chelating agents, is dedicated to leading-edge development of new chelation chemistry platforms critical for advancement of diagnostic and therapeutic medicine. (macrocyclics.com)
  • Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. (wikipedia.org)
  • Chelation is useful in applications such as providing nutritional supplements, in chelation therapy to remove toxic metals from the body, as contrast agents in MRI scanning, in manufacturing using homogeneous catalysts, in chemical water treatment to assist in the removal of metals, and in fertilizers. (wikipedia.org)
  • Chelation to the conjugate base of this ligand increases the solubility of the Gd3+ at the body's neutral pH and still allows for the paramagnetic effect required for an MRI contrast agent. (wikipedia.org)
  • forecast
  • This report studies the Formaldehyde Based Chelating Agent development status and future trend in China, focuses on top players in China, also splits Formaldehyde Based Chelating Agent by type and by applications, to fully and deeply research and reveal the market general situation and future forecast. (reportsnreports.com)
  • Pharmaceutical is anticipated to be a potential market for chelating agents over the forecast period on account of increasing government spending on providing primary healthcare facilities to its citizens. (cnbc.com)
  • DMSA
  • This agent cannot be considered a first-line drug, because DMSA is safer and more effective. (medscape.com)
  • The German Environmental Agency (Umweltbundesamt) listed DMSA and DMPS as the two most useful and safe chelating agents available. (wikipedia.org)
  • chemical
  • In September 2015, ChemPoint EMEA B.V, a company engaged in sales marketing and distribution of specialty chemicals announced that it was expanding its marketing and distribution relationship with The Dow Chemical Company by providing formulation, sales and order fulfillment support for the company's VERSENE which is food grade chelating agent and used in food applications. (cnbc.com)
  • carbon
  • It forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones. (wikipedia.org)
  • citation needed] Chelating agents, natural zeolite, activated carbon, resins, and liquid organics impregnated with chelating agents are all used to exchange cations or anions with the solution. (wikipedia.org)
  • iron
  • Ocular and ophthalmologic adverse effects may occur in patients with β-thalassemia major (BTM) treated regularly with blood transfusions and iron-chelating agents. (entjournal.com)
  • Olfactory dysfunction can occur in patients with BTM treated with iron-chelating agents. (entjournal.com)
  • There may be need to routinely provide iron chelating treatment and supplementation of vitamin A, B5 and E for transfusion-dependent subjects in the area to obviate the possible negative effect of iron overload among the subjects. (omicsonline.org)
  • In podsolisation, chelating agents break down clay and release minerals such as iron and aluminium. (wikipedia.org)
  • food
  • Chelating, or sequestering, agents protect food products from many enzymatic reactions that promote deterioration during processing and storage. (britannica.com)
  • water
  • Many microbial species produce water-soluble pigments that serve as chelating agents, termed siderophores. (wikipedia.org)
  • GdCl3∙6H2O can not be used as an MRI contrasting agent due to its low solubility in water at the body's near neutral pH. (wikipedia.org)