Checkpoint Kinase 2Cell CycleCell Cycle ProteinsGenes, cdcDNA DamageProtein-Serine-Threonine KinasesProtein KinasesG2 PhaseCell Cycle CheckpointsMitosisAtaxia Telangiectasia Mutated ProteinsS PhaseM Phase Cell Cycle CheckpointsHydroxyureaSpindle ApparatusG2 Phase Cell Cycle CheckpointsDNA RepairDNA ReplicationDNA-Binding ProteinsNuclear ProteinsSaccharomyces cerevisiae ProteinsPhosphorylationSchizosaccharomycescdc25 PhosphatasesSchizosaccharomyces pombe ProteinsG1 PhaseMutationTumor Suppressor ProteinsTumor Suppressor Protein p53CDC2 Protein KinaseSaccharomyces cerevisiaeGamma RaysFungal ProteinsRadiation, IonizingIntracellular Signaling Peptides and ProteinsUltraviolet RaysS Phase Cell Cycle CheckpointsCyclin BApoptosisMad2 ProteinsChromosomal InstabilityCyclin-Dependent Kinase Inhibitor p21Ataxia TelangiectasiaSignal TransductionCell Line, TumorGenomic InstabilityCell DivisionNocodazoleCyclinsKinetochoresMolecular Sequence DataHeLa CellsProtein Kinase InhibitorsGenes, FungalRadiation ToleranceDNA, FungalDNA Breaks, Double-StrandedCell LineModels, BiologicalPhosphatidylinositol 3-KinasesHistonesCyclin-Dependent KinasesG1 Phase Cell Cycle CheckpointsMethyl MethanesulfonateCyclin B1Gene DeletionProtein BindingFibroblastsRNA, Small InterferingBase SequenceBRCA1 ProteinAmino Acid SequenceMAP Kinase Signaling SystemCyclin-Dependent Kinase 2Cell NucleusCdc20 ProteinsFlow CytometryCell SurvivalEnzyme ActivationCell ProliferationRepressor ProteinsDNATumor Cells, CulturedCDC2-CDC28 KinasesRetinoblastoma ProteinCDC28 Protein Kinase, S cerevisiaeAneuploidyProtein-Tyrosine KinasesChromosome SegregationRNA InterferenceBlotting, WesternCaffeinePhenotypeNucleic Acid Synthesis InhibitorsCells, CulturedAurora KinasesAphidicolinHCT116 CellsCalcium-Binding ProteinsTransfection